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Actuate Therapeutics Inc stock is traded at $2.07, with a volume of 99,894. It is up +0.98% in the last 24 hours and down -14.81% over the past month. Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.
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Previous Close:
$2.05
Open:
$2.11
24h Volume:
99,894
Relative Volume:
0.63
Market Cap:
$49.53M
Revenue:
-
Net Income/Loss:
$-21.54M
P/E Ratio:
-2.0901
EPS:
-0.9904
Net Cash Flow:
$-19.60M
1W Performance:
+4.02%
1M Performance:
-14.81%
6M Performance:
-70.51%
1Y Performance:
-72.36%
1-Day Range:
Value
$1.95
$2.15
1-Week Range:
Value
$1.9111
$2.78
52-Week Range:
Value
$1.58
$9.22

Actuate Therapeutics Inc Stock (ACTU) Company Profile

Name
Name
Actuate Therapeutics Inc
Name
Phone
847-986-4190
Name
Address
1751 RIVER RUN, FORT WORTH
Name
Employee
12
Name
Twitter
Name
Next Earnings Date
2026-05-21
Name
Latest SEC Filings
Name
ACTU's Discussions on Twitter

Compare ACTU vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ACTU icon
ACTU
Actuate Therapeutics Inc
2.07 49.53M 0 -21.54M -19.60M -0.9904
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
451.63 114.63B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
609.94 63.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.72 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
278.09 37.13B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
162.99 34.65B 742.00K -1.37B -1.07B -7.0731

Actuate Therapeutics Inc Stock (ACTU) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-26-25 Initiated B. Riley Securities Buy
Apr-22-25 Initiated Craig Hallum Buy
Mar-17-25 Initiated H.C. Wainwright Buy

Actuate Therapeutics Inc Stock (ACTU) Latest News

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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 18, 2026
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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 18, 2026
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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 18, 2026
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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Institutional Confidence - TradingKey

Jun 18, 2026
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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 18, 2026
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Jun 18, 2026

Actuate Therapeutics Inc (ACTU) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 18, 2026
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Jun 16, 2026

Actuate Therapeutics Inc (ACTU) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 16, 2026
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Jun 14, 2026

ACTU Q1 2026 Earnings: Wider-than-Expected Loss Despite Positive Stock ReactionFinancial Health Score - newsline.com

Jun 14, 2026
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Jun 13, 2026

Actuate Therapeutics, Inc. Financial Disclosures & SEC Filings - TradingView

Jun 13, 2026
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Jun 11, 2026

ACTU Q1 2026 Earnings: Wider-Than-Expected Loss as Clinical-Stage Biotech Advances PipelineEarnings Volatility Report - newsline.com

Jun 11, 2026
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Jun 10, 2026

Buy Rating Reaffirmed on Elraglusib Momentum and External Validation; $15 ACTU Price Target Maintained - TipRanks

Jun 10, 2026
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Jun 10, 2026

H.C. Wainwright reiterates Actuate Therapeutics stock rating on trial inclusion - Investing.com

Jun 10, 2026
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Jun 10, 2026

H.C. Wainwright reiterates Actuate Therapeutics stock rating on trial inclusion By Investing.com - Investing.com Canada

Jun 10, 2026
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Jun 09, 2026

12 Health Care Stocks Moving In Tuesday's After-Market Session - Benzinga

Jun 09, 2026
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Jun 09, 2026

Actuate’s elraglusib to be evaluated in BEACON2 neuroblastoma trial - Investing.com

Jun 09, 2026
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Jun 09, 2026

Actuate’s elraglusib to be evaluated in BEACON2 neuroblastoma trial By Investing.com - Investing.com South Africa

Jun 09, 2026
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Jun 09, 2026

Actuate Therapeutics to Evaluate Elraglusib in BEACON2 Clinical Trial for Relapsed Neuroblastoma in Partnership with Cancer Research UK Clinical Trials Unit - Quiver Quantitative

Jun 09, 2026
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Jun 09, 2026

Experimental cancer drug elraglusib joins landmark pediatric neuroblastoma trial - Stock Titan

Jun 09, 2026
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Jun 04, 2026

Actuate Therapeutics (ACTU) Surges 6.59% as Biotech Momentum Builds Above Key SupportSystematic Flow - newsline.com

Jun 04, 2026
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Jun 01, 2026

Elraglusib shows significant survival benefits in metastatic pancreatic cancer combined with standard chemo. - Pluang

Jun 01, 2026
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Jun 01, 2026

Actuate presents elraglusib trial data at ASCO meeting By Investing.com - Investing.com South Africa

Jun 01, 2026
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Jun 01, 2026

Actuate presents elraglusib trial data at ASCO meeting - Investing.com

Jun 01, 2026
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Jun 01, 2026

Actuate Therapeutics Reports Positive Survival Outcomes for Elraglusib in Combination with Standard Chemotherapies for Metastatic Pancreatic Ductal Adenocarcinoma at ASCO 2026 - Quiver Quantitative

Jun 01, 2026
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Jun 01, 2026

Actuate Therapeutics Announces ASCO Poster Presentations - GlobeNewswire

Jun 01, 2026
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May 29, 2026

Actuate Therapeutics (ACTU) Declines 2.88% as Stock Nears Key Support ZoneEarnings Beat Stocks - The Legal Advocate

May 29, 2026
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May 27, 2026

Actuate Therapeutics (ACTU) Holds Near Support Amid Low VolatilityVolume Spike Alerts - The Legal Advocate

May 27, 2026
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May 27, 2026

Actuate Therapeutics (ACTU) Drops 4.09% as Shares Test Critical $2.00 Support LevelFlat Correction - newsline.com

May 27, 2026
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May 26, 2026

ACTU Q1 2026 Earnings: EPS Misses Estimates Amid Pre-Revenue PhaseGuidance vs Actual - Newser

May 26, 2026
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May 23, 2026

Actuate Therapeutics elects directors and ratifies auditor at annual meeting By Investing.com - Investing.com India

May 23, 2026
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May 23, 2026

Actuate Therapeutics, Inc. Files Form 8-K Current Report with SEC Detailing Company Information and Nasdaq Listing - Minichart

May 23, 2026
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May 22, 2026

Actuate Therapeutics Stockholders Elect Directors, Ratify Auditor - TipRanks

May 22, 2026
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May 22, 2026

Actuate Therapeutics elects directors and ratifies auditor at annual meeting - Investing.com

May 22, 2026
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May 22, 2026

Actuate Therapeutics, Inc.Common stock (NQ: ACTU - The Chronicle-Journal

May 22, 2026
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May 22, 2026

Actuate Therapeutics (ACTU) Holds Near Support After Modest UptickCrowd Breakout Signals - Newser

May 22, 2026
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May 19, 2026

Analysts Offer Insights on Healthcare Companies: Pyxis Oncology (PYXS) and Actuate Therapeutics, Inc. (ACTU) - The Globe and Mail

May 19, 2026
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May 19, 2026

ACTU Reiterated by HC Wainwright & Co. -- Price Target Maintained at $15 - GuruFocus

May 19, 2026
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May 18, 2026

Actuate Therapeutics Price Target Maintained With a $15.00/Share by HC Wainwright & Co. - Moomoo

May 18, 2026
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May 18, 2026

H.C. Wainwright Maintains Actuate Therapeutics(ACTU.US) With Buy Rating, Maintains Target Price $15 - Moomoo

May 18, 2026
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May 15, 2026

Actuate Therapeutics Inc reports results for the quarter ended March 31Earnings Summary - TradingView

May 15, 2026
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May 14, 2026

Actuate Therapeutics, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026 - marketscreener.com

May 14, 2026
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May 14, 2026

Analysts Are Bullish on These Healthcare Stocks: Actuate Therapeutics, Inc. (ACTU), Agios Pharma (AGIO) - The Globe and Mail

May 14, 2026
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May 13, 2026

Actuate Therapeutics Inc expected to post a loss of 22 cents a shareEarnings Preview - TradingView

May 13, 2026
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May 13, 2026

Craig-Hallum Remains a Buy on Actuate Therapeutics, Inc. (ACTU) - The Globe and Mail

May 13, 2026
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May 12, 2026

TradingKey - TradingKey

May 12, 2026
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May 12, 2026

Craig-Hallum Maintains Actuate Therapeutics(ACTU.US) With Buy Rating, Cuts Target Price to $12 - Moomoo

May 12, 2026
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May 11, 2026

Actuate Wins FDA Clearance for Oral Elraglusib Trial - TipRanks

May 11, 2026
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May 11, 2026

Actuate Therapeutics (NASDAQ: ACTU) gets FDA IND ok but flags cash risk - Stock Titan

May 11, 2026
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May 11, 2026

Actuate Therapeutics Announces FDA Clearance of IND for - GlobeNewswire

May 11, 2026
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May 11, 2026

Pancreatic cancer drug elraglusib moves to pill form after survival gains - Stock Titan

May 11, 2026
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May 06, 2026

Actuate Therapeutics Adds Oncology Expert to Board Leadership - TipRanks

May 06, 2026
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May 06, 2026

Actuate Therapeutics Adds Oncology Veteran Martin Huber to Board as Elraglusib Advances - citybiz

May 06, 2026

Actuate Therapeutics Inc Stock (ACTU) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$31.43
price up icon 0.74%
$90.89
price down icon 1.44%
$52.96
price down icon 1.38%
$63.96
price up icon 3.50%
ONC ONC
$270.15
price up icon 2.84%
$162.99
price up icon 3.31%
Cap:     |  Volume (24h):