451.24
price down icon0.61%   -2.765
pre-market  Pre-market:  451.00   -0.235   -0.05%
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Vertex Pharmaceuticals Inc stock is traded at $451.24, with a volume of 1.15M. It is down -0.61% in the last 24 hours and down -6.19% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$454.00
Open:
$458.42
24h Volume:
1.15M
Relative Volume:
0.79
Market Cap:
$114.63B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
29.43
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
-3.19%
1M Performance:
-6.19%
6M Performance:
+18.83%
1Y Performance:
-10.33%
1-Day Range:
Value
$450.97
$463.78
1-Week Range:
Value
$449.75
$468.45
52-Week Range:
Value
$362.50
$513.98

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-02-12
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
451.24 115.33B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
736.53 77.48B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
681.85 41.09B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
306.66 41.40B 3.71B 313.75M 465.38M 2.2571
INSM icon
INSM
Insmed Inc
143.98 29.32B 606.42M -1.28B -997.58M -6.403

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Mar 23, 2026

CRISPR Therapeutics Stock: Is It a Bargain Buy Right Now? - The Motley Fool

Mar 23, 2026
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Mar 23, 2026

Westview Management dba Westview Investment Advisors Invests $2.85 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 23, 2026
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Mar 23, 2026

Gradient Investments LLC Has $19.76 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 23, 2026
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Mar 23, 2026

Nordea Investment Management AB Has $202.61 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 23, 2026
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Mar 23, 2026

Vertex Pharmaceuticals Tokenized Stock (Ondo) price today, VRTXon to USD live price, marketcap and chart - CoinMarketCap

Mar 23, 2026
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Mar 22, 2026

How Vertex’s IgA Nephropathy Data and Accelerated FDA Pathway At Vertex Pharmaceuticals (VRTX) Has Changed Its Investment Story - Yahoo Finance

Mar 22, 2026
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Mar 22, 2026

Best Growth Stock to Buy Right Now: Eli Lilly vs. Vertex Pharmaceuticals - AOL.com

Mar 22, 2026
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Mar 22, 2026

Cooper Financial Group Acquires 3,021 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 22, 2026
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Mar 21, 2026

Vertex Pharma stock faces pressure amid CF dominance and pipeline uncertainties in 2026 - AD HOC NEWS

Mar 21, 2026
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Mar 20, 2026

Vertex Pharmaceuticals Analyst Ratings and Price Targets | NASDAQ:VRTX - Benzinga

Mar 20, 2026
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Mar 20, 2026

Form 144 VERTEX PHARMACEUTICALS INC / MA For: 4 March - Investing.com

Mar 20, 2026
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Mar 20, 2026

Oppenheimer upgrades Vertex Pharmaceuticals (VRTX) - MSN

Mar 20, 2026
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Mar 20, 2026

Promising Biotech Stocks To Follow TodayMarch 20th - MarketBeat

Mar 20, 2026
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Mar 20, 2026

Vertex Pharma stock faces pressure amid CF growth and pipeline uncertainties - AD HOC NEWS

Mar 20, 2026
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Mar 20, 2026

Is CRISPR Therapeutics Stock a Buy Now? - AOL.com

Mar 20, 2026
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Mar 20, 2026

Vertex Stock Falls 4.8% in a Month: Buying Opportunity or Red Flag? - TradingView

Mar 20, 2026
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Mar 20, 2026

CIBC Bancorp USA Inc. Makes New Investment in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 20, 2026
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Mar 20, 2026

Is Vertex Pharmaceuticals (VRTX) Offering Value After Recent Share Price Pullback? - simplywall.st

Mar 20, 2026
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Mar 19, 2026

Assessing Vertex Pharmaceuticals (VRTX) Valuation After Positive RAINIER Trial Update And Accelerated IgAN Filing - Yahoo Finance

Mar 19, 2026
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Mar 19, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Mar 19, 2026
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Mar 19, 2026

RBC Capital reiterates Vertex stock rating on competitive concerns - Investing.com

Mar 19, 2026
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Mar 19, 2026

Swiss Life Asset Management Ltd Buys 6,045 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 19, 2026
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Mar 19, 2026

Groupama Asset Management Trims Stake in Vertex Pharmaceuticals - National Today

Mar 19, 2026
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Mar 19, 2026

Wells Fargo Adjusts PT on Vertex Pharmaceuticals to $550 From $515, Maintains Overweight Rating - marketscreener.com

Mar 19, 2026
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Mar 19, 2026

Argus Adjusts PT on Vertex Pharmaceuticals to $520 From $475, Maintains Buy Rating - marketscreener.com

Mar 19, 2026
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Mar 19, 2026

Mirabella Financial Services LLP Raises Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 19, 2026
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Mar 19, 2026

Argus raises Vertex stock price target to $520 on CF franchise - Investing.com

Mar 19, 2026
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Mar 19, 2026

VRTX SEC FilingsVertex Pharmaceuticals Inc 10-K, 10-Q, 8-K Forms - Stock Titan

Mar 19, 2026
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Mar 19, 2026

Groupama Asset Managment Sells 17,916 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 19, 2026
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Mar 19, 2026

Vertex Pharmaceuticals Stock In Shambles: Down 9.5% With 6-Day Losing Streak - Trefis

Mar 19, 2026
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Mar 19, 2026

Vertex Pharmaceuticals Stock 6-Day Losing Spree: Stock Falls -9.5% - Trefis

Mar 19, 2026
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Mar 19, 2026

Danske Bank A S Makes New $64.42 Million Investment in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 19, 2026
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Mar 19, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by AIA Group Ltd - MarketBeat

Mar 19, 2026
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Mar 18, 2026

Vertex Pharmaceuticals (VRTX) Upgraded to Buy by Maxim Group | V - GuruFocus

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals (VRTX) Sees a More Significant Dip Than Broader Market: Some Facts to Know - Yahoo Finance

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors despite losses on the day - MarketWatch

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals (VRTX) Gains Amid Optimistic Outlook and Upgrade - GuruFocus

Mar 18, 2026
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Mar 18, 2026

Q4 Earnings Outperformers: Vertex Pharmaceuticals (NASDAQ:VRTX) And The Rest Of The Therapeutics Stocks - Yahoo Finance

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) Upgraded to "Buy" at Maxim Group - MarketBeat

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals Stock Slides 7.3% With A 5-Day Losing Spree - Trefis

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals Stock Plummets -7.3% With 5-Day Losing Streak - Trefis

Mar 18, 2026
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Mar 18, 2026

Vertex Pharmaceuticals Incorporated $VRTX is Provident Investment Management Inc.'s 4th Largest Position - MarketBeat

Mar 18, 2026
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Mar 18, 2026

Fierce Biotech Layoff Tracker 2026: Gossamer lays off 48%; Bicycle deflates - Fierce Biotech

Mar 18, 2026
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Mar 17, 2026

Physician Views Preview: How clinically meaningful are Vertex's Phase III data for povetacicept? - FirstWord Pharma

Mar 17, 2026
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Mar 17, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Mar 17, 2026
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Mar 17, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) CMO Carmen Bozic Sells 2,329 Shares - MarketBeat

Mar 17, 2026
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Mar 17, 2026

Vertex Pharmaceuticals EVP and CMO Carmen Bozic Sells Shares - TradingView

Mar 17, 2026
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Mar 17, 2026

Vertex (VRTX) EVP and CMO Carmen Bozic sells 2,329 shares in pre-set 10b5-1 trade - Stock Titan

Mar 17, 2026
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Mar 17, 2026

Top Biotech Stocks To Follow TodayMarch 17th - MarketBeat

Mar 17, 2026
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Mar 17, 2026

Mirabella Financial Services LLP Has $2.10 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 17, 2026
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Mar 17, 2026

Focus Partners Wealth Trims Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 17, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$736.53
price up icon 0.50%
$681.85
price up icon 2.70%
$306.66
price down icon 1.77%
$143.98
price up icon 5.87%
ONC ONC
$274.73
price down icon 0.20%
Cap:     |  Volume (24h):