390.76
price up icon0.23%   0.88
after-market After Hours: 390.19 -0.57 -0.15%
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Vertex Pharmaceuticals Inc stock is traded at $390.76, with a volume of 1.58M. It is up +0.23% in the last 24 hours and down -15.02% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$389.88
Open:
$389.66
24h Volume:
1.58M
Relative Volume:
0.99
Market Cap:
$100.19B
Revenue:
$11.39B
Net Income/Loss:
$3.64B
P/E Ratio:
27.93
EPS:
13.99
Net Cash Flow:
$3.50B
1W Performance:
+0.77%
1M Performance:
-15.02%
6M Performance:
-17.17%
1Y Performance:
-19.93%
1-Day Range:
Value
$388.93
$395.84
1-Week Range:
Value
$386.79
$396.72
52-Week Range:
Value
$362.50
$519.88

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2025-02-10
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
390.76 100.71B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
458.28 58.84B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
571.78 61.52B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ARGX
Argen X Se Adr
656.89 40.01B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
312.51 38.20B 3.81B -644.79M -669.77M -6.24

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
Aug 19, 2025

Vertex Says 20,000 Prescriptions Filled for Non-Opioid Pain Drug - MSN

Aug 19, 2025
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Aug 18, 2025

Stock Analysis | Vertex Pharmaceuticals OutlookA Bullish Setup with Strong Analyst Support - AInvest

Aug 18, 2025
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Aug 18, 2025

Goldman Sachs Reiterated a Buy Rating on Vertex Pharmaceuticals (VRTX), Kept the PT Unchanged - Yahoo Finance

Aug 18, 2025
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Aug 18, 2025

Living life with cystic fibrosis: The Circle of Care grant - Vertex Pharmaceuticals

Aug 18, 2025
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Aug 18, 2025

Undercovered Dozen: BrightSpire Capital, Vertex Pharmaceuticals, Adobe And More - Seeking Alpha

Aug 18, 2025
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Aug 18, 2025

Vertex Pharmaceuticals: Promising Growth with Successful Launch and Strong Pipeline - TipRanks

Aug 18, 2025
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Aug 17, 2025

Top 3 Growth Stocks to Buy in August: Eli Lilly, Summit Therapeutics, and Vertex Pharmaceuticals - AInvest

Aug 17, 2025
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Aug 16, 2025

Vertex Pharmaceuticals Inc: Financial Performance and Competitive Strengths - AInvest

Aug 16, 2025
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Aug 16, 2025

Vertex Pharmaceuticals and Netflix: High-Conviction Growth Buys in a Volatile Market - AInvest

Aug 16, 2025
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Aug 15, 2025

Vertex Pharma CEO Buys the Stock Dip - Barron's

Aug 15, 2025
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Aug 15, 2025

Up and down the ladder: The latest comings and goings - statnews.com

Aug 15, 2025
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Aug 15, 2025

Is This Beaten-Down Stock a Buy on the Dip? - AOL.com

Aug 15, 2025
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Aug 15, 2025

Vertex Inc. Downgrade: Near-Term Growth Expectations Reset - AInvest

Aug 15, 2025
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Aug 14, 2025

Joint Venture Receives $1B Refinancing for Vertex Pharmaceuticals Headquarters Facility in Boston - REBusinessOnline

Aug 14, 2025
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Aug 13, 2025

Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It - sharewise.com

Aug 13, 2025
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Aug 13, 2025

Daiwa Securities Adjusts Price Target on Vertex Pharmaceuticals to $430 From $530, Maintains Buy Rating - MarketScreener

Aug 13, 2025
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Aug 13, 2025

VRTX Q2 2025 Deep Dive: New Product Launches and Pipeline Update in a Volatile Market - Yahoo Finance

Aug 13, 2025
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Aug 13, 2025

The 5 Most Interesting Analyst Questions From Vertex Pharmaceuticals’s Q2 Earnings Call - Yahoo Finance

Aug 13, 2025
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Aug 12, 2025

Vertex Pharmaceuticals: Undervalued After Pain Drug Setbacks - AInvest

Aug 12, 2025
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Aug 12, 2025

Vertex Pharmaceuticals: The Stock Hasn't Dropped Enough Yet (NASDAQ:VRTX) - Seeking Alpha

Aug 12, 2025
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Aug 12, 2025

Vertex HQ refinanced for $1 billion - The Business Journals

Aug 12, 2025
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Aug 12, 2025

Vertex Pharmaceuticals Soars 3.44%—What’s Fueling This Biotech Breakout? - AInvest

Aug 12, 2025
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Aug 12, 2025

Analysts Are Bullish on Top Healthcare Stocks: Vertex Pharmaceuticals (VRTX), AMN Healthcare Services (AMN) - The Globe and Mail

Aug 12, 2025
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Aug 12, 2025

Vertex Pharmaceuticals' (NASDAQ:VRTX) Earnings May Just Be The Starting Point - Yahoo Finance

Aug 12, 2025
pulisher
Aug 11, 2025

Vertex Pharmaceuticals: A Biotech Powerhouse Poised for Rebound After Oversold Correction - AInvest

Aug 11, 2025
pulisher
Aug 11, 2025

Vertex Pharmaceuticals Is A Strong Buy After The Recent Pullback (Upgrade) (NASDAQ:VRTX) - Seeking Alpha

Aug 11, 2025
pulisher
Aug 11, 2025

Goldman Sachs reiterates Buy rating on Vertex stock, citing diversification By Investing.com - Investing.com South Africa

Aug 11, 2025
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Aug 11, 2025

Vertex Pharma announces new share buybacks worth up to $4B - MSN

Aug 11, 2025
pulisher
Aug 10, 2025

The week in pharma: action, reaction and insight – week to August 8 - The Pharma Letter

Aug 10, 2025
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Aug 10, 2025

Vertex Pharmaceuticals (VRTX) Hits New All-Time Low on Failed Clinical Trial - MSN

Aug 10, 2025
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Aug 10, 2025

Brazil’s Antitrust Watchdog Probes Soybean Traders Over Cartel Concerns - PYMNTS.com

Aug 10, 2025
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Aug 10, 2025

Vertex unveils positive study data for CF triple-combination regimens; shares jump - FirstWord Pharma

Aug 10, 2025
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Aug 09, 2025

KOL Views: Vertex's triplet data exceed expectations – implications for CF landscape - firstwordpharma.com

Aug 09, 2025
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Aug 09, 2025

Vertex Analyst Rating Lowered by B of A Securities; VERX Stock Price Target Cut to $34.00 - AInvest

Aug 09, 2025
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Aug 09, 2025

Moving Average Crossover Confirms Uptrend in Vertex Pharmaceuticals IncorporatedMarket Surge Signal for Swing Traders Triggered - beatles.ru

Aug 09, 2025
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Aug 09, 2025

Why Vertex Pharma Is Feeling The Pain Despite A Second-Quarter Beat - MSN

Aug 09, 2025
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Aug 09, 2025

South African Patient Groups Urge Antitrust Probe into Vertex Pharmaceuticals Over Cystic Fibrosis Drug Pricing - geneonline.com

Aug 09, 2025
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Aug 08, 2025

Hedge Fund and Insider Trading News: Ken Griffin, DE Shaw, Bobby Jain, Jim Cramer, Rokos Capital Management, Point72 Asset Management, Vertex Pharmaceuticals Inc (VRTX), Galaxy Digital Inc (GLXY), and More - Insider Monkey

Aug 08, 2025
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Aug 08, 2025

Vertex Pharmaceuticals shares fall 2.75% intraday after insider bought shares and $1.0 billion mortgage financing. - AInvest

Aug 08, 2025
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Aug 08, 2025

Vertex Pharmaceuticals Plunges 2.69%—Is This the Bottom for Vertex Pharmaceuticals? - AInvest

Aug 08, 2025
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Aug 08, 2025

Advocates urge South Africa to reopen antitrust probe into Vertex Pharmaceuticals - statnews.com

Aug 08, 2025
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Aug 08, 2025

The RMR Group Announces $1.0 Billion Refinancing of Vertex Pharmaceuticals' Headquarters in Boston Seaport District - MarketScreener

Aug 08, 2025
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Aug 07, 2025

Vertex Pharma CEO Kewalramani buys shares worth $3.89 million - Investing.com

Aug 07, 2025
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Aug 07, 2025

RMR Group secures $1 billion mortgage for Vertex Pharmaceuticals HQ By Investing.com - Investing.com Australia

Aug 07, 2025
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Aug 07, 2025

The RMR Group Announces $1.0 Billion Refinancing of Vertex Pharmaceuticals’ Headquarters in Boston Seaport District - MarketScreener

Aug 07, 2025
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Aug 07, 2025

Vertex Pharmaceuticals Executives Make Significant Stock Purchases - TradingView

Aug 07, 2025
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Aug 07, 2025

$1B Deal: RMR Group Refinances Vertex Pharma's Boston HQ with 15-Year Lease Extension - Stock Titan

Aug 07, 2025
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Aug 07, 2025

Vertex Pharmaceuticals Reports Q2 2025 Revenue Growth, Net Income Turns Positive Amidst Challenges - AInvest

Aug 07, 2025
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Aug 07, 2025

Vertex Pharmaceuticals (VRTX) Reports Strong Q2 2025 Revenue Growth with US$2,965 Million - Yahoo Finance

Aug 07, 2025
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Aug 06, 2025

Entrada (TRDA) Q2 Revenue Drops 98% - The Motley Fool

Aug 06, 2025
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Aug 06, 2025

Vertex Pharmaceuticals: Guggenheim maintains a 'Buy' Rating, The Target Price is $546 - AInvest

Aug 06, 2025

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Vertex Pharmaceuticals Inc Stock (VRTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
SACHS BRUCE I
Director
Aug 06 '25
Buy
389.68
5,000
1,948,416
45,000
$458.28
price up icon 0.31%
$571.78
price down icon 0.37%
$656.89
price down icon 0.67%
biotechnology ONC
$312.51
price down icon 2.13%
$127.21
price down icon 0.05%
Cap:     |  Volume (24h):