434.52
price up icon0.23%   0.98
after-market After Hours: 433.80 -0.72 -0.17%
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Vertex Pharmaceuticals Inc stock is traded at $434.52, with a volume of 1.75M. It is up +0.23% in the last 24 hours and down -0.72% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$433.54
Open:
$437.07
24h Volume:
1.75M
Relative Volume:
1.36
Market Cap:
$110.28B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
25.76
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-0.56%
1M Performance:
-0.72%
6M Performance:
+1.82%
1Y Performance:
+0.11%
1-Day Range:
Value
$432.96
$438.84
1-Week Range:
Value
$426.01
$444.32
52-Week Range:
Value
$362.50
$507.92

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-05-04
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.52 110.03B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
638.88 67.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
806.46 50.76B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
297.45 40.12B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
151.56 32.68B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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May 22, 2026

Vertex Pharma stock (US92532F1003): Health Canada review for new pain drug puts pipeline in focus - AD HOC NEWS

May 22, 2026
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May 21, 2026

VRTX: Vertex Pharmaceuticals Seeks Approval for New Pain Treatme - GuruFocus

May 21, 2026
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May 21, 2026

Vertex Announces New Drug Submission for Suzetrigine Has Been Accepted for Review by Health Canada for the Treatment of Moderate-to-Severe Acute Pain in Adults - PR Newswire Canada

May 21, 2026
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May 21, 2026

What Are Wall Street Analysts' Target Price for Vertex Pharmaceuticals Stock? - Yahoo Finance

May 21, 2026
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May 21, 2026

Assessing Vertex Pharmaceuticals (VRTX) Valuation After Recent Share Price Weakness - Yahoo Finance

May 21, 2026
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May 21, 2026

Vertex Pharmaceuticals Earnings Call Highlights New Growth Engines - TipRanks

May 21, 2026
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May 21, 2026

Is Vertex Pharmaceuticals Successfully Diversifying Beyond Cystic Fibrosis - Kavout

May 21, 2026
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May 21, 2026

VRTX Technical Analysis | Trend, Signals & Chart Patterns | VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX) - ChartMill

May 21, 2026
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May 21, 2026

Vertex Pharma stock (US92532F1003): cystic fibrosis leader eyes new growth drivers after latest pipe - AD HOC NEWS

May 21, 2026
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May 20, 2026

META_TITLE_QUOTE - Yahoo Finance

May 20, 2026
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May 20, 2026

Vertex Pharma stock (US92532F1003): cystic fibrosis leader eyes gene-editing future - AD HOC NEWS

May 20, 2026
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May 20, 2026

Vertex Pharmaceuticals’ SWOT analysis: kidney drug stock draws mixed views - Investing.com Australia

May 20, 2026
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May 20, 2026

VRTX News | VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX) - ChartMill

May 20, 2026
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May 20, 2026

J&J’s Duato makes 358 times his median employee; Vertex CEO makes just 80 times - BioSpace

May 20, 2026
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May 20, 2026

Vertex Pharma stock (US92532F1003): insider selling puts focus on biotech heavyweight - AD HOC NEWS

May 20, 2026
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May 19, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

May 19, 2026
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May 19, 2026

Vertex Pharmaceuticals Inc (VRTX) Stock Price, Trades & News - GuruFocus

May 19, 2026
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May 19, 2026

Vertex Pharmaceuticals Insider Sold Shares Worth $613,971, According to a Recent SEC Filing - Moomoo

May 19, 2026
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May 19, 2026

VRTX: CF and pipeline innovation drive growth, with JOURNAVX and Povi poised for major impact - TradingView

May 19, 2026
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May 19, 2026

Vertex (VRTX) CSO Mark Bunnage sells 33 shares in pre-set 10b5-1 trade - Stock Titan

May 19, 2026
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May 19, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It - Yahoo Finance

May 19, 2026
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May 19, 2026

Vertex Pharma stock (US92532F1003): cystic fibrosis leader after solid quarterly results - AD HOC NEWS

May 19, 2026
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May 18, 2026

North Dakota State Investment Board Buys Shares of 8,821 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 18, 2026
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May 18, 2026

Canada Post Corp Registered Pension Plan Has $2.94 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 18, 2026
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May 17, 2026

Vertex Pharma stock (US92532F1003): focus on cystic fibrosis and expanding pipeline - AD HOC NEWS

May 17, 2026
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May 17, 2026

Vertex Pharma stock (US92532F1003): institutional flows and pipeline keep focus on biotech heavyweig - AD HOC NEWS

May 17, 2026
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May 17, 2026

Vertex Pharmaceuticals stock (US92532F1003): gene-editing hopes meet kidney data buzz - AD HOC NEWS

May 17, 2026
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May 17, 2026

Leuthold Group LLC Boosts Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 17, 2026
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May 17, 2026

STF Management LP Lowers Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 17, 2026
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May 16, 2026

Vertex Pharmaceuticals Incorporated (VX1.DE) Stock Price, News, Quote & History - Yahoo Finance

May 16, 2026
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May 16, 2026

Vertex Pharmaceuticals Incorporated (VRTX.VI) Stock Price, News, Quote & History - Yahoo Finance

May 16, 2026
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May 16, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Purchased by DNB Asset Management AS - MarketBeat

May 16, 2026
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May 16, 2026

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Average Recommendation of "Moderate Buy" by Analysts - MarketBeat

May 16, 2026
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May 16, 2026

Allworth Financial LP Has $6.36 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 16, 2026
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May 15, 2026

Vertex Pharmaceuticals Inc. stock underperforms Friday when compared to competitors - MarketWatch

May 15, 2026
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May 15, 2026

Vertex Pharma stock (US92532F1003): Q1 numbers, ESOP shelf and gene-editing momentum draw investor f - AD HOC NEWS

May 15, 2026
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May 15, 2026

Vertex Pharmaceuticals (NASDAQ: VRTX) insider files Form 144 to sell vested shares - Stock Titan

May 15, 2026
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May 15, 2026

Mark Bunnage sells shares at VRTX (NASDAQ: VRTX) in Form 144 filing - Stock Titan

May 15, 2026
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May 15, 2026

FY2027 Earnings Forecast for VRTX Issued By Erste Group Bank - MarketBeat

May 15, 2026
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May 15, 2026

Daiwa Securities Adjusts PT on Vertex Pharmaceuticals to $555 From $561, Maintains Buy Rating - marketscreener.com

May 15, 2026
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May 15, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by Atria Investments Inc - MarketBeat

May 15, 2026
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May 14, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) CMO Carmen Bozic Sells 6,988 Shares - MarketBeat

May 14, 2026
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May 14, 2026

Vertex (VRTX) CMO Carmen Bozic sells 6,988 shares in planned 10b5-1 trade - Stock Titan

May 14, 2026
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May 14, 2026

Capital World Investors (NASDAQ: VRTX) reports 10.1% stake in Vertex - Stock Titan

May 14, 2026
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May 14, 2026

Vertex Pharmaceuticals stock (US92532F1003): Shareholder approval fuels biotech momentum - AD HOC NEWS

May 14, 2026
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May 14, 2026

Capital Research discloses 21.1M-share stake in Vertex (NASDAQ: VRTX) - Stock Titan

May 14, 2026
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May 14, 2026

Vertex Pharma stock (US92532F1003): Shares up 1.06% to $453 amid biotech strength - AD HOC NEWS

May 14, 2026
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May 14, 2026

Vertex Pharmaceuticals posts mixed Q1; investors focus on non-CF pipeline for growth - MSN

May 14, 2026
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May 14, 2026

Pacer Advisors Inc. Buys 9,641 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 14, 2026
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May 14, 2026

Bank Julius Baer & Co. Ltd Zurich Sells 10,154 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 14, 2026
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May 14, 2026

Baader Bank Aktiengesellschaft Purchases New Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

May 14, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$638.88
price down icon 0.58%
$806.46
price down icon 1.20%
$297.45
price down icon 1.02%
$151.56
price down icon 1.41%
ONC ONC
$310.25
price up icon 0.20%
Cap:     |  Volume (24h):