448.40
price up icon1.45%   6.41
after-market After Hours: 448.40
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Vertex Pharmaceuticals Inc stock is traded at $448.40, with a volume of 1.38M. It is up +1.45% in the last 24 hours and up +2.22% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$441.99
Open:
$443.41
24h Volume:
1.38M
Relative Volume:
0.84
Market Cap:
$115.95B
Revenue:
$11.10B
Net Income/Loss:
$-988.90M
P/E Ratio:
-114.39
EPS:
-3.92
Net Cash Flow:
$-1.26B
1W Performance:
-0.89%
1M Performance:
+2.22%
6M Performance:
+0.20%
1Y Performance:
-4.04%
1-Day Range:
Value
$440.00
$451.63
1-Week Range:
Value
$440.00
$460.10
52-Week Range:
Value
$377.85
$519.88

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2025-02-10
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
448.40 115.95B 11.10B -988.90M -1.26B -3.92
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
513.58 56.52B 14.09B 4.50B 2.96B 39.28
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
312.32 39.44B 2.35B -269.70M -75.39M -2.09
Biotechnology icon
ARGX
Argen X Se Adr
537.92 35.14B 2.58B 1.06B -1.28B 16.33
Biotechnology icon
ONC
Beone Medicines Ltd Adr
252.78 28.51B 3.81B -644.79M -669.77M -6.24

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Jun 18, 2025

10 Biotech Stocks Screaming a Buy - Insider Monkey

Jun 18, 2025
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Jun 18, 2025

Vertex Pharmaceuticals (VRTX) Soared as Investors Back Strategic Initiatives - Insider Monkey

Jun 18, 2025
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Jun 18, 2025

RBC Capital Sticks to Their Hold Rating for Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Jun 18, 2025
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Jun 17, 2025

Vertex Pharmaceuticals (VRTX) Price Target Slightly Reduced by R - GuruFocus

Jun 17, 2025
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Jun 17, 2025

A Glimpse Into The Expert Outlook On Vertex Pharmaceuticals Through 10 Analysts - Nasdaq

Jun 17, 2025
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Jun 17, 2025

Vertex Pharmaceuticals price target lowered to $420 from $423 at RBC Capital - TipRanks

Jun 17, 2025
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Jun 17, 2025

Vertex Pharmaceuticals (VRTX) Price Target Lowered Amid Concerns - GuruFocus

Jun 17, 2025
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Jun 17, 2025

Vertex Pharmaceuticals (VRTX) Price Target Lowered Amid Concerns | VRTX Stock News - GuruFocus

Jun 17, 2025
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Jun 17, 2025

RBC Capital Adjusts PT on Vertex Pharmaceuticals to $420 From $423, Maintains Sector Perform Rating - MarketScreener

Jun 17, 2025
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Jun 16, 2025

Saudia Arabia Introduces Strategic Healthcare Vision and Global Partnerships at BIO 2025 - GlobeNewswire Inc.

Jun 16, 2025
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Jun 16, 2025

Aries Wealth Management Buys New Shares in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 16, 2025
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Jun 16, 2025

Everhart Financial Group Inc. Buys 553 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 16, 2025
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Jun 16, 2025

CCM Investment Advisers LLC Acquires 5,351 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 16, 2025
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Jun 16, 2025

Opinicus Capital Inc. Invests $397,000 in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 16, 2025
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Jun 16, 2025

Ferguson Wellman Capital Management Inc. Takes $391,000 Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 16, 2025
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Jun 15, 2025

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Acquired by RMR Wealth Builders - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Integrated Advisors Network LLC Has $1.05 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Optas LLC Has $864,000 Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Brighton Jones LLC Purchases 1,994 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Foster Victor Wealth Advisors LLC Sells 1,664 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Massachusetts Wealth Management Makes New Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Yousif Capital Management LLC Sells 664 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Simplicity Wealth LLC Has $630,000 Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 15, 2025

Redhawk Wealth Advisors Inc. Cuts Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 15, 2025
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Jun 14, 2025

Vertex Pharmaceuticals’ SWOT analysis: stock poised for growth amid pipeline expansion - Investing.com

Jun 14, 2025
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Jun 14, 2025

Compagnie Lombard Odier SCmA Raises Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

Simon Quick Advisors LLC Has $1.42 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

SG Americas Securities LLC Purchases 17,502 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

Greenwood Capital Associates LLC Sells 6,572 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

Stanley Laman Group Ltd. Buys New Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

UMB Bank n.a. Sells 1,666 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 14, 2025
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Jun 14, 2025

Vertex Pharma announces new share buybacks worth up to $4B - MSN

Jun 14, 2025
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Jun 13, 2025

Vertex Pharmaceuticals (VRTX) Stock Moves -1.00%: What You Should Know - Yahoo Finance

Jun 13, 2025
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Jun 13, 2025

Vertex Pharmaceuticals Stock Outlook: Is Wall Street Bullish or Bearish? - MSN

Jun 13, 2025
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Jun 13, 2025

Handelsbanken Fonder AB Trims Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 13, 2025
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Jun 12, 2025

Healey boosts life sciences tax incentives as 33 companies plan major expansions - The Business Journals

Jun 12, 2025
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Jun 12, 2025

Boston drug company laying off 125 employees in R.I. - Boston.com

Jun 12, 2025
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Jun 12, 2025

Boston probes misconduct claims against city official - Axios

Jun 12, 2025
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Jun 12, 2025

Portside Wealth Group LLC Has $1.43 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 12, 2025
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Jun 11, 2025

Vertex Presents New Data on the Benefits of ALYFTREK - Insider Monkey

Jun 11, 2025
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Jun 11, 2025

Vertex Pharmaceuticals lays off 125 workers in RI - WPRI.com

Jun 11, 2025
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Jun 11, 2025

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Stake Lifted by Wedmont Private Capital - MarketBeat

Jun 11, 2025
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Jun 11, 2025

Boston drugmaker Vertex slashes Providence workforce, shrinks real estate following trial failure - The Business Journals

Jun 11, 2025
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Jun 11, 2025

SeaCrest Wealth Management LLC Purchases New Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) - MarketBeat

Jun 11, 2025
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Jun 11, 2025

Vertex to lay off 125 employees in R.I., consolidate offices - The Boston Globe

Jun 11, 2025
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Jun 11, 2025

Vertex lays off 125 staffers, slims Rhode Island campus after ditching failed diabetes cell-device combo - Fierce Biotech

Jun 11, 2025
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Jun 11, 2025

Vertex lays off 125 staffers after halting work on diabetes 'cells plus device' therapy - FirstWord Pharma

Jun 11, 2025
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Jun 11, 2025

After axing diabetes asset, Vertex lays off 140 staff - PharmaLive

Jun 11, 2025
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Jun 11, 2025

After Axing Diabetes Asset, Vertex Lays Off 140 Staff - BioSpace

Jun 11, 2025
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Jun 11, 2025

Five things: The Newbury GM, Zoominfo cuts, Vertex, Boston Scientific and casino night - The Business Journals

Jun 11, 2025
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Jun 11, 2025

How Is Vertex Pharmaceuticals’ Stock Performance Compared to Other Biotech Stocks? - MSN

Jun 11, 2025

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$513.58
price up icon 0.93%
$312.32
price up icon 1.17%
$537.92
price down icon 0.52%
biotechnology ONC
$252.78
price down icon 0.52%
$104.40
price down icon 0.54%
Cap:     |  Volume (24h):