444.93
price down icon0.03%   -0.115
pre-market  Pre-market:  443.55   -1.375   -0.31%
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Vertex Pharmaceuticals Inc stock is traded at $444.93, with a volume of 924.13K. It is down -0.03% in the last 24 hours and down -0.75% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$445.04
Open:
$440.02
24h Volume:
924.13K
Relative Volume:
0.73
Market Cap:
$112.92B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
26.38
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-0.43%
1M Performance:
-0.75%
6M Performance:
-1.57%
1Y Performance:
-3.29%
1-Day Range:
Value
$440.02
$447.70
1-Week Range:
Value
$433.80
$449.50
52-Week Range:
Value
$362.50
$507.92

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
444.93 112.92B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
612.14 64.18B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
893.52 55.57B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
282.85 37.76B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
153.87 32.71B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Jun 14, 2026

Vertex Pharma Stock (US92532F1003): Analyst sentiment and ownership moves keep VRTX in focus - AD HOC NEWS

Jun 14, 2026
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Jun 13, 2026

Is It Time to Buy This Turnaround Pharma Stock? - NAI500

Jun 13, 2026
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Jun 12, 2026

Swiss National Bank Reduces Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
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Jun 12, 2026

Meiji Yasuda America Inc Invests $1.91 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
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Jun 12, 2026

Aviva PLC Buys 11,322 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
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Jun 12, 2026

Vertex Extends Pediatric Pipeline As Shares Trade Below Consensus Targets - Yahoo Finance

Jun 12, 2026
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Jun 11, 2026

Vertex Pharmaceuticals (VRTX) Rises Higher Than Market: Key Facts - Yahoo Finance Singapore

Jun 11, 2026
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Jun 11, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Jun 11, 2026
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Jun 11, 2026

Is Vertex Pharmaceuticals Incorporated (VRTX) A Good Stock To Buy Now? - Insider Monkey

Jun 11, 2026
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Jun 11, 2026

Vertex Says Pediatric CASGEVY Data Show Consistent Benefits In Rare Blood Disorders - Benzinga

Jun 11, 2026
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Jun 11, 2026

Goldman Sachs Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $641 - Moomoo

Jun 11, 2026
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Jun 11, 2026

Vertex CASGEVY pediatric data shows 100% success in CRISPR trials - grafa.com

Jun 11, 2026
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Jun 11, 2026

Zions Bancorporation National Association UT Grows Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

Vertex Pharmaceuticals (VRTX) Reports Positive Data for Casgevy in Pediatrics - GuruFocus

Jun 11, 2026
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Jun 11, 2026

Illinois Municipal Retirement Fund Reduces Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

LPL Financial LLC Has $125.53 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

Fierce Biotech Layoff Tracker 2026: Genentech trims R&D; Fulcrum shrinks headcount 85% - Fierce Biotech

Jun 11, 2026
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Jun 11, 2026

MFS Blended Research Core Equity Portfolio's Vertex Pharmaceuticals Inc(VRTX) Holding History - GuruFocus

Jun 11, 2026
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Jun 11, 2026

Vertex Presents New Data on CASGEVY®, Including First European Presentation of Data in Children Ages 5–11, at the European Hematology Association Congress and Announces Additional Global Regulatory Submissions - Business Wire

Jun 11, 2026
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Jun 10, 2026

Vertex Pharmaceuticals (VRTX) Declines More Than Market: Some Information for Investors - Yahoo Finance

Jun 10, 2026
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Jun 10, 2026

Vertex Pharmaceuticals Inc. stock underperforms Wednesday when compared to competitors - MarketWatch

Jun 10, 2026
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Jun 10, 2026

Vertex Pharmaceuticals stock (US92532F1003): Insider sale draws attention amid strong biotech pipeli - AD HOC NEWS

Jun 10, 2026
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Jun 10, 2026

VRTX: Pipeline momentum in CF, pain, and kidney disease drives innovation-led growth outlook - TradingView

Jun 10, 2026
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Jun 10, 2026

VRTX: Expanding CF, pain, and renal franchises with robust late-stage pipeline and innovation focus - TradingView

Jun 10, 2026
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Jun 10, 2026

Vertex Pharma stock (US92532F1003): focus on cystic fibrosis growth and pipeline potential - AD HOC NEWS

Jun 10, 2026
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Jun 10, 2026

Motley Fool Asset Management LLC Has $10.70 Million Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Motley Fool Wealth Management LLC Decreases Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Franklin Resources Inc. Increases Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Deutsche Bank AG Has $801.94 Million Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Receives Average Rating of "Moderate Buy" from Brokerages - MarketBeat

Jun 10, 2026
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Jun 09, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Jun 09, 2026
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Jun 09, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) CMO Carmen Bozic Sells 1,745 Shares - MarketBeat

Jun 09, 2026
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Jun 09, 2026

Vertex Pharmaceuticals Insider Sold Shares Worth $785,250, According to a Recent SEC Filing - marketscreener.com

Jun 09, 2026
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Jun 09, 2026

Vertex Pharmaceuticals (VRTX) EVP and CMO sells 1,745 shares in planned trade - Stock Titan

Jun 09, 2026
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Jun 09, 2026

Can Vertex Pharmaceuticals Deepen Its Cystic Fibrosis Edge? - Kalkine Media

Jun 09, 2026
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Jun 09, 2026

O Shaughnessy Asset Management LLC Buys 11,564 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 09, 2026
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Jun 09, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by Cerity Partners LLC - MarketBeat

Jun 09, 2026
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Jun 08, 2026

Kyverna vs. Vertex: Clinical-Stage Risk vs. Cash-Flow Stability in Biotech InvestingNews and Statistics - IndexBox

Jun 08, 2026
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Jun 08, 2026

Kyverna Therapeutics vs. Vertex Pharmaceuticals: Which Drug Developer Stock Is a Better Buy in 2026? - Yahoo Finance

Jun 08, 2026
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Jun 08, 2026

Membranous Nephropathy Market Emerging as a High-Growth Healthcare Investment Space Through 2036 – DelveInsight | Roche, BeOne Medicines, Biogen, Vertex Pharma, AstraZeneca, Alexion Pharma, Climb Bio - Barchart.com

Jun 08, 2026
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Jun 08, 2026

Vertex Pharmaceuticals (VRTX) Stock Analysis: Uncovering A 22.80% Potential Upside - DirectorsTalk Interviews

Jun 08, 2026
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Jun 07, 2026

News | Not built for eternity: Design technique looks to avoid permanence - CoStar

Jun 07, 2026
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Jun 07, 2026

Vertex Presents New Data on ALYFTREK® at European Cystic Fibrosis Conference - BioSpace

Jun 07, 2026
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Jun 07, 2026

WINTON GROUP Ltd Purchases New Shares in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026
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Jun 07, 2026

ING Groep NV Has $36.78 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Clearbridge Investments LLC Grows Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Vertex Pharmaceuticals Incorporated $VRTX is Capital World Investors' 10th Largest Position - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Capital International Investors Increases Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by Capital International Sarl - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Capital International Inc. CA Decreases Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026
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Jun 07, 2026

Capital Group Investment Management PTE. LTD. Sells 5,421 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 07, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$612.14
price up icon 0.11%
$893.52
price down icon 0.60%
$282.85
price down icon 2.26%
$153.87
price up icon 3.11%
ONC ONC
$264.48
price up icon 1.62%
Cap:     |  Volume (24h):