508.75
price up icon2.06%   10.25
after-market After Hours: 508.75
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Vertex Pharmaceuticals Inc stock is traded at $508.75, with a volume of 2.24M. It is up +2.06% in the last 24 hours and down -1.14% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$498.50
Open:
$514.91
24h Volume:
2.24M
Relative Volume:
1.74
Market Cap:
$128.95B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
30.16
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
+1.09%
1M Performance:
-1.14%
6M Performance:
+15.18%
1Y Performance:
+24.72%
1-Day Range:
Value
$507.21
$517.68
1-Week Range:
Value
$484.08
$517.68
52-Week Range:
Value
$403.16
$560.25

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-11-02
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
508.75 128.95B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
236.50 94.42B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
796.34 81.99B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
846.27 53.22B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
374.08 42.32B 5.76B 514.49M 1.10B 4.4813

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-21-26 Initiated Leerink Partners Outperform
Sep-02-26 Resumed Morgan Stanley Overweight
May-27-26 Resumed Truist Buy
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
Oct 13, 2026

Moderna vs. Vertex Pharmaceuticals: Which Healthcare Stock Is a Better Buy in 2026? - The Motley Fool

Oct 13, 2026
pulisher
Oct 11, 2026

Which iShares Healthcare ETF Is the Better Buy: Biotech-Focused IBB or Broad IYH? - The Motley Fool

Oct 11, 2026
pulisher
Oct 09, 2026

Vertex Pharmaceuticals (VRTX) Beats Stock Market Upswing: What Investors Need to Know - Zacks Investment Research

Oct 09, 2026
pulisher
Oct 09, 2026

Is Vertex Stock Worth More Than Its Competitors? - Trefis

Oct 09, 2026
pulisher
Oct 09, 2026

If You Invested $100 In Vertex Pharmaceuticals Stock 5 Years Ago, You Would Have This Much Today - Benzinga

Oct 09, 2026
pulisher
Oct 09, 2026

RBC raises target for Vertex Pharma stock from USD 570 to USD 576 - AD HOC NEWS

Oct 09, 2026
pulisher
Oct 08, 2026

RBC Lifts Price Target on Vertex Pharmaceuticals to $576 From $570, Keeps Outperform Rating - www.marketscreener.com

Oct 08, 2026
pulisher
Oct 07, 2026

Vertex to Announce Third Quarter 2026 Financial Results November 2nd - Business Wire

Oct 07, 2026
pulisher
Oct 06, 2026

Vertex Pharmaceuticals Incorpor (VRTX) Stock forecasts - Yahoo Finance UK

Oct 06, 2026
pulisher
Oct 06, 2026

Vertex Pharma stock after-hours at EUR 446.63: minus 0.62 percent versus prior close - AD HOC NEWS

Oct 06, 2026
pulisher
Oct 06, 2026

Vertex Pharmaceuticals Incorpor (VRTX) Stock Forecasts - Yahoo Finance

Oct 06, 2026
pulisher
Oct 06, 2026

Novavax (NVAX) Surges 20.1%: Is This an Indication of Further Gains? - Zacks Investment Research

Oct 06, 2026
pulisher
Oct 05, 2026

Healthcare Sector Highlights 16 A+ Growth Stocks Including Verte - GuruFocus

Oct 05, 2026
pulisher
Oct 05, 2026

Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know - Yahoo Finance

Oct 05, 2026
pulisher
Oct 04, 2026

Amgen vs. Vertex Pharmaceuticals: Which Biotech Stock Is a Better Buy in 2026? - The Motley Fool

Oct 04, 2026
pulisher
Oct 02, 2026

Vertex (VRTX) or Regeneron (REGN)? Two Biotech Moats, Two Very Different Bets - Yahoo Finance

Oct 02, 2026
pulisher
Oct 01, 2026

Vertex Pharmaceuticals And 2 Other Top Gene Therapy Stocks - Yahoo Finance

Oct 01, 2026
pulisher
Oct 01, 2026

Vertex Pharmaceuticals (VRTX) Stock Falls Amid Market Uptick: What Investors Need to Know - Zacks Investment Research

Oct 01, 2026
pulisher
Oct 01, 2026

Vertex Pharmaceuticals (VRTX) Stock Falls Amid Market Uptick: What Investors Need to Know - Yahoo Finance

Oct 01, 2026
pulisher
Oct 01, 2026

Vertex Pharmaceuticals Inc. stock underperforms Thursday when compared to competitors - MarketWatch

Oct 01, 2026
pulisher
Oct 01, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Moved Down by 3.21% on Oct 1: What Investors Need To Know - TradingKey

Oct 01, 2026
pulisher
Oct 01, 2026

M&A slows in Q3 but Vertex snags one of the year’s biggest in $10B Crinetics buy - BioSpace

Oct 01, 2026
pulisher
Sep 29, 2026

$100 Invested In Vertex Pharmaceuticals 10 Years Ago Would Be Worth This Much Today - Benzinga

Sep 29, 2026
pulisher
Sep 29, 2026

Vertex Pharmaceuticals- Still Too Much Emphasis On CF SupremacyI Foresee A Downgrade - Seeking Alpha

Sep 29, 2026
pulisher
Sep 29, 2026

2 Wall Street Analysts Think Vertex Pharmaceuticals Stock Can Soar Another 20% or More Over the Next 12 Months. Here's Why They're Right. - The Motley Fool

Sep 29, 2026
pulisher
Sep 29, 2026

UBS Raises Vertex Pharmaceuticals Price Target to $615 From $585, Maintains Buy Rating - Moomoo

Sep 29, 2026
pulisher
Sep 29, 2026

2 Wall Street Analysts Think Vertex Pharmaceuticals Stock Can Soar Another 20% or More Over the Next 12 Months. Here's Why They're Right. - Yahoo Finance

Sep 29, 2026
pulisher
Sep 28, 2026

Could Vertex Pharmaceuticals (VRTX)’s Kidney Breakthrough Unlock a New Opportunity for Maze Therapeutics (MAZE)? - Yahoo Finance

Sep 28, 2026
pulisher
Sep 28, 2026

Vertex Pharmaceuticals Incorpor (VRTX) Stock Forecasts - Yahoo Finance

Sep 28, 2026
pulisher
Sep 27, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Options ChainYahoo Finance - Yahoo! Finance Canada

Sep 27, 2026
pulisher
Sep 24, 2026

Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know - Yahoo Finance

Sep 24, 2026
pulisher
Sep 24, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Sep 24, 2026
pulisher
Sep 24, 2026

BMO Capital Remains a Buy on Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Sep 24, 2026
pulisher
Sep 24, 2026

Vertex Pharmaceuticals (VRTX) Gets a Hold from Canaccord Genuity - The Globe and Mail

Sep 24, 2026
pulisher
Sep 24, 2026

Analysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX) and Roivant Sciences (ROIV) - The Globe and Mail

Sep 24, 2026
pulisher
Sep 23, 2026

Vertex (VRTX) Stock Could Be 24% Undervalued As Kidney Trial Progress Continues - Yahoo Finance

Sep 23, 2026
pulisher
Sep 23, 2026

Vertex Pharma options analysis: heavy put activity signals near-term caution - Investing.com

Sep 23, 2026
pulisher
Sep 23, 2026

Vertex Posts Positive Phase II Data on Kidney Disease Drug - Zacks Investment Research

Sep 23, 2026
pulisher
Sep 23, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Options ChainYahoo Finance - Yahoo! Finance Canada

Sep 23, 2026
pulisher
Sep 23, 2026

Vertex Pharmaceuticals (VRTX) Q2 2026 Earnings Call Transcript - fortune.com

Sep 23, 2026
pulisher
Sep 22, 2026

Better Healthcare ETF: Invesco's Biotech-Focused IBBQ vs. iShares' Broad IYH - The Motley Fool

Sep 22, 2026
pulisher
Sep 22, 2026

The Surprise That Sent Vertex — And Its Chief Rival — Soaring - Investor's Business Daily

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex Pharmaceuticals Stock Gains On Kidney Drug DataVertex Pharmaceuticals (NASDAQ:VRTX) - Benzinga

Sep 22, 2026
pulisher
Sep 22, 2026

Twin Moves: VRTX Rises On Kidney Disease Trial Results, MAZE Rallies Harder - Yahoo Finance

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex’s Kidney Drug Success Sparks a 22% Surge for This Rival Biotech - Barron's

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex Pharmaceuticals stock gains as inaxaplin data advance - AD HOC NEWS

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex Announces Positive Results From Phase 2b AMPLIFIED Study of Inaxaplin in Additional Populations of People With APOL1-Mediated Kidney Disease (AMKD) and Completion of Enrollment in the Phase 2/3 AMPLITUDE Trial - BioSpace

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex’s midstage data amplify kidney disease market opportunity - Fierce Biotech

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex Pharmaceuticals Reports Positive Results for Inaxaplin Kidney Disease Trial - marketscreener.com

Sep 22, 2026
pulisher
Sep 22, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It - Yahoo Finance

Sep 22, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Vertex Pharmaceuticals Inc Stock (VRTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Tatsis Ourania
EVP, Chief Reg. & Quality Off.
Jul 02 '26
Sale
524.99
1,500
787,485
45,321
McKechnie Duncan
EVP, Chief Commercial Officer
Jul 02 '26
Sale
519.00
1,541
799,779
11,001
Tatsis Ourania
Officer
Jul 02 '26
Proposed Sale
524.99
1,500
787,485
0
McKechnie Duncan
Officer
Jul 02 '26
Proposed Sale
519.00
1,541
799,779
0
Liu Joy
EVP and Chief Legal Officer
Jul 01 '26
Sale
502.71
828
416,244
19,131
Liu Joy
Officer
Jul 01 '26
Proposed Sale
502.71
828
416,244
0
Bozic Carmen
EVP and CMO
Jun 26 '26
Sale
482.50
596
287,570
15,337
Bozic Carmen
Officer
Jun 26 '26
Proposed Sale
482.50
596
287,570
0
Bozic Carmen
Officer
Jun 18 '26
Proposed Sale
462.17
1,020
471,413
0
Bozic Carmen
EVP and CMO
Jun 18 '26
Sale
462.17
1,020
471,413
15,933
$236.50
price up icon 4.51%
$796.34
price up icon 2.31%
$846.27
price up icon 3.42%
ONC ONC
$374.08
price up icon 6.43%
$189.26
price down icon 2.20%
$234.03
price up icon 4.26%
Cap:     |  Volume (24h):