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Vertex Pharmaceuticals Inc stock is traded at $477.36, with a volume of 1.25M. It is up +0.90% in the last 24 hours and up +0.45% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$473.09
Open:
$476.05
24h Volume:
1.25M
Relative Volume:
0.85
Market Cap:
$121.16B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
28.30
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-1.71%
1M Performance:
+0.45%
6M Performance:
+1.91%
1Y Performance:
+1.08%
1-Day Range:
Value
$472.57
$484.00
1-Week Range:
Value
$465.00
$491.23
52-Week Range:
Value
$362.50
$533.67

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
477.36 121.16B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
656.01 68.78B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
918.22 57.44B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
189.23 40.23B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
271.77 36.28B 4.29B 577.22M 641.34M 4.2086

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
01:36 AM

Vertex Pharma stock trades near record levels as cystic fibrosis franchise drives earnings growth - AD HOC NEWS

01:36 AM
pulisher
Jul 24, 2026

Form 4 Vertex Pharmaceuticals Inc For: 24 July By Investing.com - Investing.com Nigeria

Jul 24, 2026
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Jul 24, 2026

Vertex Pharmaceuticals Inc (VRTX) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 24, 2026
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Jul 24, 2026

VRTX|Vertex Pharmaceuticals Inc|Price:473.090| - TradingKey

Jul 24, 2026
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Jul 24, 2026

Vertex Pharma stock trades near record territory as cystic fibrosis franchise drives earnings growth - AD HOC NEWS

Jul 24, 2026
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Jul 23, 2026

Vertex Pharmaceuticals (VRTX) EVP Amit Sachdev receives 8,251-share equity grant - Stock Titan

Jul 23, 2026
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Jul 23, 2026

iShares Global Healthcare ETF vs VanEck Biotech ETF: Which ETF Is Better for Profiting With Healthcare in 2026? - The Motley Fool

Jul 23, 2026
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Jul 23, 2026

Vertex stock consolidates after strong Q1 2026 revenue growth - Ad-hoc-news.de

Jul 23, 2026
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Jul 23, 2026

3 Healthcare Stocks with Competitive Advantages - Yahoo! Finance Canada

Jul 23, 2026
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Jul 23, 2026

Missed AI, Memory Bull Run? Biotech May Be The Next Breakout Trade — But Retail Sentiment Has Never Been Lower - Yahoo Finance

Jul 23, 2026
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Jul 23, 2026

Vertex Pharmaceuticals Inc (VRTX) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jul 23, 2026
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Jul 22, 2026

Vertex Pharmaceuticals (VRTX) Sees a More Significant Dip Than Broader Market: Some Facts to Know - Yahoo Finance

Jul 22, 2026
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Jul 22, 2026

Vertex was sole bidder in high-premium Crinetics acquisition - BioPharma Dive

Jul 22, 2026
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Jul 22, 2026

Vertex Pharmaceuticals Inc. stock underperforms Wednesday when compared to competitors - MarketWatch

Jul 22, 2026
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Jul 22, 2026

Vertex was only bidder for Crinetics in year’s second-highest M&A premium - Endpoints News

Jul 22, 2026
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Jul 22, 2026

Vertex-Crinetics Pharmaceuticals deal faces Australian review - MLex

Jul 22, 2026
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Jul 22, 2026

VRTX|Vertex Pharmaceuticals Inc|Price:473.290|Chg%:+0.720 - TradingKey

Jul 22, 2026
pulisher
Jul 21, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX): An Affordable Growth Stock Balancing Strong Fundamentals With Reasonable Valuation - ChartMill

Jul 21, 2026
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Jul 21, 2026

Morgan Stanley Downgrades Vertex Pharmaceuticals to Equalweight From Overweight, Adjusts PT to $15 From $19 - marketscreener.com

Jul 21, 2026
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Jul 20, 2026

Why Vertex Pharmaceuticals (VRTX) Dipped More Than Broader Market Today - Yahoo Finance

Jul 20, 2026
pulisher
Jul 20, 2026

Vertex Pharmaceuticals Inc. stock underperforms Monday when compared to competitors - MarketWatch

Jul 20, 2026
pulisher
Jul 20, 2026

Goldman Sachs Adjusts Price Target on Vertex Pharmaceuticals to $652 From $641, Maintains Buy Rating - Moomoo

Jul 20, 2026
pulisher
Jul 20, 2026

Vertex Pharma stock trades near highs as cystic fibrosis portfolio drives double digit revenue growt - Ad-hoc-news.de

Jul 20, 2026
pulisher
Jul 20, 2026

Vertex’s IgA nephropathy drug derisked after Novartis, Vera approvals - PharmaLive

Jul 20, 2026
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Jul 20, 2026

Vertex Pharmaceuticals (VRTX) Stock Analysis: A Healthcare Giant with 14% Upside Potential - DirectorsTalk Interviews

Jul 20, 2026
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Jul 20, 2026

How FDA’s Pediatric Expansion of Casgevy at Vertex Pharmaceuticals (VRTX) Has Changed Its Investment Story - Yahoo Finance

Jul 20, 2026
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Jul 20, 2026

Vertex Pharmaceuticals (VRTX) Wins FDA Nod To Treat Children As Young As 2 - Yahoo Finance Singapore

Jul 20, 2026
pulisher
Jul 19, 2026

Vertex Pharmaceuticals just made a $10 billion acquisition worth watching - MSN

Jul 19, 2026
pulisher
Jul 19, 2026

Vertex Pharmaceuticals Just Made a $10 Billion Acquisition Worth Watching - The Motley Fool

Jul 19, 2026
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Jul 19, 2026

Latigo preps IPO to fund non-opioid rival to Vertex’s Journax - Fierce Biotech

Jul 19, 2026
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Jul 18, 2026

Vertex Pharma stock steadies as cystic fibrosis franchise drives revenue and investors watch next da - ad-hoc-news.de

Jul 18, 2026
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Jul 18, 2026

Vertex Pharmaceuticals (VRTX) Q1 2026 Earnings Call Transcript - Fortune

Jul 18, 2026
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Jul 17, 2026

Vertex Pharmaceuticals (VRTX) awards 99.941 deferred stock units to director - Stock Titan

Jul 17, 2026
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Jul 17, 2026

5 Best Biotech Stocks for 2026 and How to Invest - The Motley Fool

Jul 17, 2026
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Jul 17, 2026

Parkinson’s in the Clinic, Insilico enters Phase III, Vertex Acquires Crinetics - Genetic Engineering and Biotechnology News

Jul 17, 2026
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Jul 16, 2026

Vertex Pharma stock trades near record highs as cystic fibrosis franchise drives earnings momentum - Ad Hoc News

Jul 16, 2026
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Jul 16, 2026

Vertex Pharmaceuticals Inc. stock underperforms Thursday when compared to competitors despite daily gains - MarketWatch

Jul 16, 2026
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Jul 16, 2026

Lobbying Update: $1,200,000 of VERTEX PHARMACEUTICALS INCORPORATED lobbying was just disclosed - Quiver Quantitative

Jul 16, 2026
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Jul 16, 2026

Is Vertex Pharmaceuticals Successfully Diversifying Beyond Cystic Fibrosis - Kavout | AI

Jul 16, 2026
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Jul 16, 2026

Vertex Pharmaceuticals Inc Stock Price Live, Charts & News - The Economic Times

Jul 16, 2026
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Jul 16, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It - Yahoo Finance

Jul 16, 2026
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Jul 16, 2026

Citi Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $585 - Moomoo

Jul 16, 2026
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Jul 16, 2026

Vertex Pharma stock steadies as analysts watch cystic fibrosis - ad-hoc-news.de

Jul 16, 2026
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Jul 15, 2026

Vertex Pharmaceuticals (Ondo Tokenized) price today, VRTXON to USD live price, marketcap and chart - CoinDesk

Jul 15, 2026
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Jul 15, 2026

Vertex Pharmaceuticals Currently Down Seven Consecutive Days, on Pace for Longest Losing Streak Since August 2021 -- Data Talk - Moomoo

Jul 15, 2026
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Jul 15, 2026

Vertex Pharmaceuticals Stock 6-Day Losing Spree: Stock Falls 10% - Trefis

Jul 15, 2026
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Jul 15, 2026

Vertex to Acquire Crinetics Pharmaceuticals (CRNX) in $85 Per Share Cash Deal - Yahoo Finance

Jul 15, 2026
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Jul 15, 2026

Vertex Pharmaceuticals Stock Slides 10% Over 6 Straight Down Days - Trefis

Jul 15, 2026
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Jul 15, 2026

Crinetics Pharmaceuticals (CRNX) Looks Fully Valued As Vertex Agrees $85 Per Share Deal - simplywall.st

Jul 15, 2026
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Jul 14, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by Calamos Advisors LLC - InsuranceNewsNet

Jul 14, 2026
pulisher
Jul 14, 2026

A Quick Look at Today's Ratings for Vertex Pharmaceuticals(VRTX.US), With a Forecast Between $550 to $600 - Moomoo

Jul 14, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Vertex Pharmaceuticals Inc Stock (VRTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
McKechnie Duncan
EVP, Chief Commercial Officer
Jul 02 '26
Sale
519.00
1,541
799,779
11,001
Liu Joy
EVP and Chief Legal Officer
Jul 01 '26
Sale
502.71
828
416,244
19,131
$656.01
price up icon 0.63%
$918.22
price down icon 0.69%
$189.23
price up icon 0.25%
$271.77
price up icon 1.13%
ONC ONC
$325.90
price down icon 0.27%
Cap:     |  Volume (24h):