474.27
price down icon2.42%   -11.76
after-market After Hours: 473.45 -0.82 -0.17%
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Vertex Pharmaceuticals Inc stock is traded at $474.27, with a volume of 1.06M. It is down -2.42% in the last 24 hours and up +1.86% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$486.03
Open:
$478.95
24h Volume:
1.06M
Relative Volume:
0.75
Market Cap:
$120.48B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
30.93
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
-2.70%
1M Performance:
+1.86%
6M Performance:
+19.58%
1Y Performance:
-1.87%
1-Day Range:
Value
$471.58
$484.10
1-Week Range:
Value
$471.58
$498.02
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-02-12
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
474.27 123.47B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
766.66 83.60B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
748.72 46.83B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
318.65 43.11B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
297.04 34.79B 4.98B 69.60M 525.67M 0.5198

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Mar 03, 2026

Vertex at TD Cowen Conference: Strategic Growth and Innovation By Investing.com - Investing.com India

Mar 03, 2026
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Mar 03, 2026

Vertex Pharma Stock: Why Wall Street Is Quietly Buying the Dip - AD HOC NEWS

Mar 03, 2026
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Mar 03, 2026

Victory Capital Management Inc. Buys 92,402 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 03, 2026
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Mar 03, 2026

Absci Strengthens Clinical Leadership with Appointment of Ransi Somaratne, M.D., FACC, MBA as Chief Medical Officer - GlobeNewswire Inc.

Mar 03, 2026
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Mar 03, 2026

VRTX Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

Mar 03, 2026
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Mar 03, 2026

American Century Companies Reduces Vertex Pharmaceuticals Stake - National Today

Mar 03, 2026
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Mar 02, 2026

BMO Maintains Outperform on VRTX, Vertex Pharmaceuticals Incorporated Mar 2026 - Meyka

Mar 02, 2026
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Mar 02, 2026

Joy Liu reports multiple share sales for VRTX (NASDAQ: VRTX) in Form 144 - Stock Titan

Mar 02, 2026
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Mar 02, 2026

Vertex Pharmaceuticals Inc. stock underperforms Monday when compared to competitors - MarketWatch

Mar 02, 2026
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Mar 02, 2026

Vertex (VRTX) SVP & Chief Accounting Officer sells 357 shares in open-market trade - Stock Titan

Mar 02, 2026
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Mar 02, 2026

Vertex Gets Rating Upgrade, Earnings Rose Every Quarter This Past Year - Investor's Business Daily

Mar 02, 2026
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Mar 02, 2026

Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know - Yahoo Finance

Mar 02, 2026
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Mar 02, 2026

111 Capital Invests $1.71 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 02, 2026
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Mar 02, 2026

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Mar 02, 2026
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Mar 01, 2026

Vertex Interest Renews CRISPR Therapeutics Takeover Talk And Investor Questions - simplywall.st

Mar 01, 2026
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Mar 01, 2026

Vertex Pharmaceuticals Incorporated $VRTX Stock Holdings Lessened by US Bancorp DE - MarketBeat

Mar 01, 2026
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Mar 01, 2026

Huntington National Bank Lowers Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 01, 2026
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Mar 01, 2026

American Century Companies Inc. Lowers Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 01, 2026
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Feb 28, 2026

CRISPR Therapeutics Takeover Chatter With Vertex Puts Investor Tradeoffs In Focus - simplywall.st

Feb 28, 2026
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Feb 28, 2026

A Look At Vertex Pharmaceuticals (VRTX) Valuation As Shares Trade Near Vestra Fair Value Estimate - Yahoo Finance

Feb 28, 2026
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Feb 28, 2026

Wealthedge Investment Advisors LLC Invests $965,000 in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 28, 2026
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Feb 28, 2026

Rafferty Asset Management LLC Purchases 6,020 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 28, 2026
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Feb 28, 2026

Vertex Pharmaceuticals Inc (NASDAQ:VRTX) Shows High Technical and Setup Ratings for Potential Breakout - ChartMill

Feb 28, 2026
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Feb 28, 2026

Andra AP fonden Acquires New Shares in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 28, 2026
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Feb 28, 2026

Here’s What Analysts Are Saying About Vertex Pharmaceuticals (VRTX) - Insider Monkey

Feb 28, 2026
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Feb 27, 2026

VRTX (NASDAQ: VRTX) files Form 144 to sell 40,000 common shares - Stock Titan

Feb 27, 2026
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Feb 27, 2026

Vertex Broadens Growth Story With Gene Editing And Non Opioid Pain Therapies - simplywall.st

Feb 27, 2026
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Feb 27, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Bought by Mitsubishi UFJ Asset Management Co. Ltd. - MarketBeat

Feb 27, 2026
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Feb 27, 2026

Intech Investment Management LLC Has $13.46 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 27, 2026
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Feb 27, 2026

TD Asset Management Inc Sells 247,634 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 27, 2026
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Feb 27, 2026

Erste Asset Management GmbH Has $26.69 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 27, 2026
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Feb 27, 2026

Insider Selling: Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Sells 58,613 Shares of Stock - MarketBeat

Feb 27, 2026
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Feb 27, 2026

Vertex Pharmaceuticals Incorporated $VRTX Holdings Raised by Banco Santander S.A. - MarketBeat

Feb 27, 2026
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Feb 26, 2026

Insider Selling: Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Sells 1,846 Shares of Stock - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Ourania Tatsis Sells 260 Shares - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) CAO Kristen Ambrose Sells 223 Shares - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Mark Bunnage Sells 620 Shares - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Insider Selling: Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Sells 4,910 Shares of Stock - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals EVP Sachdev sells $897k in shares By Investing.com - Investing.com Canada

Feb 26, 2026
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Feb 26, 2026

Vertex Pharma EVP McKechnie sells $2.39m in shares By Investing.com - Investing.com Nigeria

Feb 26, 2026
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Feb 26, 2026

Insider Sell: Jonathan Biller Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Feb 26, 2026
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Feb 26, 2026

Vertex Pharma EVP McKechnie sells $2.39m in shares - Investing.com

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals EVP Tatsis sells $126k in stock - Investing.com UK

Feb 26, 2026
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Feb 26, 2026

Vertex Pharmaceuticals Incorporated : Statement of Changes in Beneficial Ownership (Form 4) - marketscreener.com

Feb 26, 2026
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Feb 26, 2026

Vertex (VRTX) EVP Atkinson trades shares under Rule 10b5-1 plan - Stock Titan

Feb 26, 2026
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Feb 26, 2026

Daiwa Securities Adjusts Vertex Pharmaceuticals PT to $561 From $500, Maintains Buy Rating - marketscreener.com

Feb 26, 2026
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Feb 26, 2026

Vertex Pharma Stock: Is Wall Street Too Cautious After The Neuropathy Surprise? - AD HOC NEWS

Feb 26, 2026
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Feb 25, 2026

Vertex Pharmaceutical uses MicroStrategy as a one-stop shop for business intelligence. - Strategy

Feb 25, 2026
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Feb 25, 2026

Vertex Pharmaceuticals's Options: A Look at What the Big Money is Thinking - Benzinga

Feb 25, 2026
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Feb 25, 2026

Vertex Pharmaceuticals (VRTX) Form 144 lists insider sales and restricted vesting - Stock Titan

Feb 25, 2026
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Feb 24, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Feb 24, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$766.66
price down icon 3.05%
$748.72
price down icon 1.06%
$318.65
price down icon 1.97%
biotechnology ONC
$297.04
price down icon 5.51%
$147.00
price up icon 0.46%
Cap:     |  Volume (24h):