461.24
price down icon0.48%   -2.24
after-market After Hours: 462.00 0.76 +0.16%
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Vertex Pharmaceuticals Inc stock is traded at $461.24, with a volume of 1.85M. It is down -0.48% in the last 24 hours and down -0.56% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$463.48
Open:
$460.43
24h Volume:
1.85M
Relative Volume:
1.31
Market Cap:
$117.03B
Revenue:
$11.74B
Net Income/Loss:
$3.68B
P/E Ratio:
32.51
EPS:
14.1888
Net Cash Flow:
$3.34B
1W Performance:
-1.97%
1M Performance:
-0.56%
6M Performance:
+23.17%
1Y Performance:
+1.32%
1-Day Range:
Value
$454.40
$464.73
1-Week Range:
Value
$454.40
$478.54
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2025-02-10
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
461.24 117.59B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
778.97 79.81B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
834.55 51.56B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
322.28 42.67B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
351.27 39.11B 4.98B 69.60M 525.67M 0.5198

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
06:17 AM

Vertex Pharmaceuticals (VRTX) Q4 Earnings Preview: Key Expectati - GuruFocus

06:17 AM
pulisher
12:55 PM

Biotech Stocks To Add to Your WatchlistFebruary 11th - MarketBeat

12:55 PM
pulisher
09:01 AM

Vertex Pharmaceuticals's Earnings Outlook - Benzinga

09:01 AM
pulisher
08:39 AM

Wealthfront Advisers LLC Trims Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

08:39 AM
pulisher
05:40 AM

Caprock Group LLC Acquires Shares of 25,216 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

05:40 AM
pulisher
Feb 10, 2026

Vertex Pharmaceuticals (VRTX) Q4 Earnings: What To Expect - Finviz

Feb 10, 2026
pulisher
Feb 10, 2026

Vertex Pharmaceuticals (VRTX) Receives FDA Orphan Drug Status fo - GuruFocus

Feb 10, 2026
pulisher
Feb 10, 2026

1 Reason I'd Buy Vertex Pharmaceuticals Stock and Never Sell - Yahoo Finance

Feb 10, 2026
pulisher
Feb 10, 2026

1 Reason I'd Buy Vertex Pharmaceuticals Stock and Never Sell - The Motley Fool

Feb 10, 2026
pulisher
Feb 10, 2026

Vertex Pharmaceuticals at Turning Point Ahead of Phase 3 Kidney Drug Data, RBC Says - marketscreener.com

Feb 10, 2026
pulisher
Feb 10, 2026

Vertex Gears Up to Report Q4 Earnings: Is a Beat in the Cards? - TradingView

Feb 10, 2026
pulisher
Feb 10, 2026

Should You Buy Vertex Before Feb. 12? - Nasdaq

Feb 10, 2026
pulisher
Feb 10, 2026

Oppenheimer Asset Management Inc. Grows Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 10, 2026
pulisher
Feb 10, 2026

A Look At Vertex Pharmaceuticals (VRTX) Valuation After Recent Share Price Momentum - Yahoo Finance

Feb 10, 2026
pulisher
Feb 09, 2026

How Investors Are Reacting To Vertex (VRTX) Expanding Into Trispecific T-Cell Engagers For Autoimmune Diseases - Yahoo Finance UK

Feb 09, 2026
pulisher
Feb 09, 2026

2 Top Healthcare Stocks to Buy in February - AOL.com

Feb 09, 2026
pulisher
Feb 09, 2026

Should You Buy Vertex Pharmaceuticals Before Feb. 12? - The Globe and Mail

Feb 09, 2026
pulisher
Feb 09, 2026

Will These 5 Drug Bigwigs Surpass Q4 Earnings Forecasts? - The Globe and Mail

Feb 09, 2026
pulisher
Feb 09, 2026

Vertex Q4 Earnings Preview: What To Expect This Week (NASDAQ:VRTX) - Seeking Alpha

Feb 09, 2026
pulisher
Feb 09, 2026

Seeking Clues to Vertex (VRTX) Q4 Earnings? A Peek Into Wall Street Projections for Key Metrics - Yahoo Finance

Feb 09, 2026
pulisher
Feb 09, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by ProShare Advisors LLC - MarketBeat

Feb 09, 2026
pulisher
Feb 09, 2026

Stocks Generating Improved Relative Strength: Vertex Pharmaceuticals - Investor's Business Daily

Feb 09, 2026
pulisher
Feb 07, 2026

BI Asset Management Fondsmaeglerselskab A S Sells 3,075 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 07, 2026
pulisher
Feb 06, 2026

Assessing Vertex Pharmaceuticals (VRTX) Valuation After Autoimmune Pipeline Expansion With WuXi Biologics - simplywall.st

Feb 06, 2026
pulisher
Feb 06, 2026

Hantz Financial Services Inc. Purchases 4,864 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 06, 2026
pulisher
Feb 06, 2026

Envestnet Asset Management Inc. Has $184.37 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 06, 2026
pulisher
Feb 06, 2026

Five things for pharma marketers to know for Friday, February 6, 2026 - Medical Marketing and Media

Feb 06, 2026
pulisher
Feb 05, 2026

Best Biotech Stocks of 2026 and How to Invest in Them - The Motley Fool

Feb 05, 2026
pulisher
Feb 05, 2026

Vertex Pharmaceuticals (VRTX) Earnings Expected to Grow: What to Know Ahead of Next Week's Release - Finviz

Feb 05, 2026
pulisher
Feb 05, 2026

Does WuXi Trispecific T-cell Engager Deal Reshape the Bull Case for Vertex Pharmaceuticals (VRTX)? - simplywall.st

Feb 05, 2026
pulisher
Feb 05, 2026

Vertex’s CRISPR treatment for sickle cell disease hits unexpected roadblock - statnews.com

Feb 05, 2026
pulisher
Feb 05, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by AGF Management Ltd. - MarketBeat

Feb 05, 2026
pulisher
Feb 05, 2026

ABN AMRO Bank N.V. Increases Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 05, 2026
pulisher
Feb 05, 2026

Is Vertex Pharmaceuticals (VRTX) Pricing Reflect Long Term Cash Flow Potential After Recent Pullback - Yahoo Finance

Feb 05, 2026
pulisher
Feb 05, 2026

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Receives Consensus Rating of "Moderate Buy" from Analysts - MarketBeat

Feb 05, 2026
pulisher
Feb 05, 2026

Vertex Pharmaceuticals (VRTX) Projected to Post Earnings on Thursday - MarketBeat

Feb 05, 2026
pulisher
Feb 04, 2026

Vertex Pharma wins EU backing to expand label for Kaftrio cystic fibrosis drug - MSN

Feb 04, 2026
pulisher
Feb 04, 2026

The Truth About Vertex Pharma: Why Wall Street Suddenly Can’t Shut Up - AD HOC NEWS

Feb 04, 2026
pulisher
Feb 04, 2026

Callan Family Office LLC Has $4.39 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 04, 2026
pulisher
Feb 04, 2026

Machina Capital S.A.S. Acquires Shares of 11,167 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 04, 2026
pulisher
Feb 04, 2026

Analysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX) and Brookdale Senior Living (BKD) - The Globe and Mail

Feb 04, 2026
pulisher
Feb 04, 2026

Rep. David Taylor Sells Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Stock - MarketBeat

Feb 04, 2026
pulisher
Feb 03, 2026

WUXI BIO, Vertex Pharmaceuticals Sign License & Research Service Agreement for T-cell Engager - AASTOCKS.com

Feb 03, 2026
pulisher
Feb 03, 2026

Biopharma bites: Updated data for Ultragenyx's gene therapy, AI newco's $13.5M seed round, plus more from NMD, Vertex - FirstWord Pharma

Feb 03, 2026
pulisher
Feb 03, 2026

Is Trending Stock Vertex Pharmaceuticals Incorporated (VRTX) a Buy Now? - Yahoo Finance

Feb 03, 2026
pulisher
Feb 03, 2026

Here's How Much a $1000 Investment in Vertex Pharmaceuticals Made 10 Years Ago Would Be Worth Today - Yahoo Finance

Feb 03, 2026
pulisher
Feb 03, 2026

WuXi licenses trispecific immune engager to Vertex - The Pharma Letter

Feb 03, 2026
pulisher
Feb 03, 2026

Vertex (VRTX) Secures Exclusive Rights for Innovative Autoimmune Treatment - GuruFocus

Feb 03, 2026
pulisher
Feb 03, 2026

Thrivent Financial for Lutherans Sells 9,932 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 03, 2026
pulisher
Feb 03, 2026

Atlantic Union Bankshares Corp Purchases 5,741 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 03, 2026
pulisher
Feb 03, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by WCM Investment Management LLC - MarketBeat

Feb 03, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$778.97
price up icon 3.19%
$834.55
price up icon 0.17%
$322.28
price down icon 0.22%
biotechnology ONC
$351.27
price down icon 0.61%
$148.43
price down icon 0.08%
Cap:     |  Volume (24h):