370.00
price up icon1.24%   4.54
after-market After Hours: 370.00
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Alnylam Pharmaceuticals Inc stock is traded at $370.00, with a volume of 1.88M. It is up +1.24% in the last 24 hours and down -9.25% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$365.46
Open:
$365.5
24h Volume:
1.88M
Relative Volume:
1.40
Market Cap:
$48.88B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,538.46
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
+2.99%
1M Performance:
-9.25%
6M Performance:
+13.75%
1Y Performance:
+38.82%
1-Day Range:
Value
$363.36
$376.87
1-Week Range:
Value
$347.76
$376.87
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
370.00 48.28B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
467.35 117.00B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
755.51 78.75B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
827.02 50.52B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ONC
Beone Medicines Ltd Adr
338.81 37.81B 4.98B 69.59M 525.67M 0.5197

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
12:54 PM

Should Alnylam’s Aggressive 2026 Revenue Guidance Reframe the Risk‑Reward for Alnylam Pharmaceuticals (ALNY) Investors? - simplywall.st

12:54 PM
pulisher
07:17 AM

31,152 Shares in Alnylam Pharmaceuticals, Inc. $ALNY Bought by Rakuten Investment Management Inc. - MarketBeat

07:17 AM
pulisher
05:45 AM

Nanomedicine Market Reached USD 169.51 Billion in 2024, to Reach - openPR.com

05:45 AM
pulisher
Jan 21, 2026

Amyloidosis Therapeutic Market to Worth Over US$ 6.37 Billion by 2033 | Astute Analytica - GlobeNewswire Inc.

Jan 21, 2026
pulisher
Jan 20, 2026

Technical Reactions to ALNY Trends in Macro Strategies - Stock Traders Daily

Jan 20, 2026
pulisher
Jan 20, 2026

RBC Capital Maintains Rating but Lowers Alnylam Pharmaceuticals (ALNY) Price Target | ALNY Stock News - GuruFocus

Jan 20, 2026
pulisher
Jan 20, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Given New $376.00 Price Target at Wells Fargo & Company - MarketBeat

Jan 20, 2026
pulisher
Jan 20, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Lowered to $465.00 at Royal Bank Of Canada - MarketBeat

Jan 20, 2026
pulisher
Jan 20, 2026

356,529 Shares in Alnylam Pharmaceuticals, Inc. $ALNY Purchased by Massachusetts Financial Services Co. MA - MarketBeat

Jan 20, 2026
pulisher
Jan 20, 2026

Allstate Corp Acquires Shares of 4,571 Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 20, 2026
pulisher
Jan 19, 2026

Price Action: What analysts say about Alnylam Pharmaceuticals Inc stockWeekly Investment Summary & High Accuracy Investment Entry Signals - baoquankhu1.vn

Jan 19, 2026
pulisher
Jan 19, 2026

Alnylam Wins EC Nod for Label Expansion of Amvuttra for ATTR-CM - MSN

Jan 19, 2026
pulisher
Jan 19, 2026

4 Next-Gen Candidates That Could Form the Future of Alzheimer’s Treatment - BioSpace

Jan 19, 2026
pulisher
Jan 18, 2026

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Sees Significant Growth in Short Interest - MarketBeat

Jan 18, 2026
pulisher
Jan 17, 2026

Aug Volume: How does Alnylam Pharmaceuticals Inc perform in inflationary periodsJuly 2025 Opening Moves & Stock Portfolio Risk Management - baoquankhu1.vn

Jan 17, 2026
pulisher
Jan 17, 2026

Is It Time To Reassess Alnylam Pharmaceuticals (ALNY) After Recent RNAi Pipeline Progress? - simplywall.st

Jan 17, 2026
pulisher
Jan 17, 2026

Wolverine Asset Management LLC Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 17, 2026
pulisher
Jan 16, 2026

Campbell & CO Investment Adviser LLC Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 16, 2026
pulisher
Jan 16, 2026

A Look Into Alnylam Pharmaceuticals Inc's Price Over Earnings - Sahm

Jan 16, 2026
pulisher
Jan 15, 2026

Insider Selling: Jeffrey V Poulton Unloads $1.01M Of Alnylam Pharmaceuticals Stock - Benzinga

Jan 15, 2026
pulisher
Jan 15, 2026

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat

Jan 15, 2026
pulisher
Jan 14, 2026

How Does Geopolitics Affect the Life Sciences Industry? 3 Executives Weigh In - MedCity News

Jan 14, 2026
pulisher
Jan 14, 2026

Alnylam EVP Pushkal Garg sells $547k in stock By Investing.com - Investing.com South Africa

Jan 14, 2026
pulisher
Jan 14, 2026

Alnylam EVP Pushkal Garg sells $547k in stock - Investing.com

Jan 14, 2026
pulisher
Jan 14, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) EVP Sells $1,008,778.60 in Stock - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) EVP Sells $547,933.70 in Stock - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

Insider Selling: Alnylam Pharmaceuticals (NASDAQ:ALNY) EVP Sells 1,510 Shares of Stock - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

Insider Selling: Alnylam Pharmaceuticals (NASDAQ:ALNY) EVP Sells 2,290 Shares of Stock - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

JPM preannouncements: Why Alnylam and Sarepta lost, but Day One won - MSN

Jan 14, 2026
pulisher
Jan 14, 2026

Is It Time To Reassess Alnylam (ALNY) After Recent Share Price Pullback? - Yahoo Finance

Jan 14, 2026
pulisher
Jan 14, 2026

JPM26: 2025 a “breakout year” for rare disease biotechs - Yahoo Finance

Jan 14, 2026
pulisher
Jan 14, 2026

Aug Gainers: What is ORLYs book value per shareQuarterly Profit Summary & Technical Entry and Exit Alerts - baoquankhu1.vn

Jan 14, 2026
pulisher
Jan 14, 2026

A Look At Alnylam Pharmaceuticals (ALNY) Valuation After Unveiling Its Alnylam 2030 Growth Plan - Yahoo Finance

Jan 14, 2026
pulisher
Jan 13, 2026

Alnylam Pharmaceuticals (ALNY) Is Down 9.0% After Ambitious 2026 Guidance And 2030 Plan Reveal - Yahoo Finance

Jan 13, 2026
pulisher
Jan 13, 2026

Market Review: What dividend safety score for Alnylam Pharmaceuticals Inc stockIndex Update & Reliable Intraday Trade Alerts - moha.gov.vn

Jan 13, 2026
pulisher
Jan 13, 2026

H.C. Wainwright reiterates Buy rating on Alnylam stock with $570 price target - Investing.com UK

Jan 13, 2026
pulisher
Jan 13, 2026

Tokio Marine Asset Management Co. Ltd. Takes $2.03 Million Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 13, 2026
pulisher
Jan 13, 2026

Sumitomo Mitsui Trust Group Inc. Grows Stock Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 13, 2026
pulisher
Jan 13, 2026

Alnylam Pharmaceuticals CEO on Development Goals, Profitability - marketscreener.com

Jan 13, 2026
pulisher
Jan 12, 2026

Alnylam stock sinks nearly 7% after Amvuttra revenue miss; what to watch next for ALNY - TechStock²

Jan 12, 2026
pulisher
Jan 12, 2026

JPM preannouncements take their toll as Alnylam slides, Tempus, Day One pop - MSN

Jan 12, 2026
pulisher
Jan 12, 2026

Lobbying Update: $70,000 of ALNYLAM PHARMACEUTICALS INC. lobbying was just disclosed - Quiver Quantitative

Jan 12, 2026
pulisher
Jan 12, 2026

JPM 2026: Year kicks off with biopharma Q4 revenue and guidance - BioWorld MedTech

Jan 12, 2026
pulisher
Jan 12, 2026

Alnylam stock slides after “Alnylam 2030” plan, Amvuttra Q4 sales come up short - TechStock²

Jan 12, 2026
pulisher
Jan 12, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Shares Gap Down After Analyst Downgrade - MarketBeat

Jan 12, 2026
pulisher
Jan 12, 2026

Alnylam Pharmaceuticals Unveils “Alnylam 2030” as Amvuttra Drives Breakout Growth at JPMorgan Conf. - MarketBeat

Jan 12, 2026
pulisher
Jan 12, 2026

JPM Kicks Off With Alnylam In the Red; But Others Surge - Investor's Business Daily

Jan 12, 2026
pulisher
Jan 12, 2026

What's Going On With Alnylam Pharma Stock Monday?Alnylam Pharmaceuticals (NASDAQ:ALNY) - Benzinga

Jan 12, 2026
pulisher
Jan 12, 2026

Alnylam (ALNY) Projects Strong Revenue Growth for 2026 Amidst TT - GuruFocus

Jan 12, 2026
pulisher
Jan 12, 2026

AbbVie buys into PD-1/VEGF sweepstakes; Alnylam and Vertex set expectations - BioPharma Dive

Jan 12, 2026
pulisher
Jan 12, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Cut to $529.00 by Analysts at Bank of America - MarketBeat

Jan 12, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$827.02
price up icon 1.30%
biotechnology ONC
$338.81
price down icon 0.83%
$160.39
price up icon 2.60%
$118.47
price up icon 0.40%
$118.81
price up icon 1.09%
Cap:     |  Volume (24h):