322.28
price down icon0.22%   -0.70
after-market After Hours: 322.00 -0.28 -0.09%
loading
Alnylam Pharmaceuticals Inc stock is traded at $322.28, with a volume of 1.58M. It is down -0.22% in the last 24 hours and down -19.08% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
See More
Previous Close:
$322.98
Open:
$322.14
24h Volume:
1.58M
Relative Volume:
1.10
Market Cap:
$42.58B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,340.04
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
-8.43%
1M Performance:
-19.08%
6M Performance:
-25.91%
1Y Performance:
+19.81%
1-Day Range:
Value
$317.80
$325.04
1-Week Range:
Value
$317.80
$350.50
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY vs VRTX, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
322.28 42.67B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
461.24 117.59B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
778.97 79.81B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
834.55 51.56B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ONC
Beone Medicines Ltd Adr
351.27 39.11B 4.98B 69.60M 525.67M 0.5198

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Resumed Barclays Overweight
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
11:16 AM

Alnylam earnings ahead: Can blockbuster TTR drug deliver? By Investing.com - Investing.com Canada

11:16 AM
pulisher
Feb 10, 2026

Envestnet Asset Management Inc. Has $54.25 Million Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Feb 10, 2026
pulisher
Feb 09, 2026

Countdown to Alnylam (ALNY) Q4 Earnings: A Look at Estimates Beyond Revenue and EPS - Yahoo Finance

Feb 09, 2026
pulisher
Feb 09, 2026

Does Alnylam Pharmaceuticals (NASDAQ:ALNY) Have A Healthy Balance Sheet? - Yahoo Finance

Feb 09, 2026
pulisher
Feb 09, 2026

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Receives Consensus Rating of "Moderate Buy" from Analysts - MarketBeat

Feb 09, 2026
pulisher
Feb 09, 2026

Down 34% From All-Time Highs, Can Alnylam Pharmaceuticals Stock Finally Recover In 2026? - TIKR.com

Feb 09, 2026
pulisher
Feb 09, 2026

Alnylam Pharmaceuticals (ALNY) Investor Outlook: Unpacking A 46.21% Potential Upside - DirectorsTalk Interviews

Feb 09, 2026
pulisher
Feb 08, 2026

Do options traders know something about Alnylam Pharmaceuticals stock we don't? - MSN

Feb 08, 2026
pulisher
Feb 07, 2026

Alnylam Heart Drug Approval Sets Up Challenge With Pfizer - MSN

Feb 07, 2026
pulisher
Feb 06, 2026

Insider Trends: Should value investors consider Alnylam Pharmaceuticals Inc2025 AllTime Highs & Risk Controlled Stock Pick Alerts - baoquankhu1.vn

Feb 06, 2026
pulisher
Feb 06, 2026

Do Options Traders Know Something About Alnylam Pharmaceuticals Stock We Don't? - TradingView

Feb 06, 2026
pulisher
Feb 05, 2026

Alnylam Pharmaceuticals (ALNY) Earnings Expected to Grow: Should You Buy? - Finviz

Feb 05, 2026
pulisher
Feb 05, 2026

Alnylam Pharmaceuticals, Inc. $ALNY Shares Acquired by Hantz Financial Services Inc. - MarketBeat

Feb 05, 2026
pulisher
Feb 04, 2026

Is There An Opportunity With Alnylam Pharmaceuticals, Inc.'s (NASDAQ:ALNY) 49% Undervaluation? - Yahoo Finance

Feb 04, 2026
pulisher
Feb 04, 2026

A Look At Alnylam Pharmaceuticals (ALNY) Valuation After New Revenue Outlook And Long Term Growth Targets - simplywall.st

Feb 04, 2026
pulisher
Feb 03, 2026

Alnylam Pharmaceuticals (BIT:1ALNY) Price Target Decreased by 11.40% to 411.81 - Nasdaq

Feb 03, 2026
pulisher
Feb 02, 2026

Alnylam Pharmaceuticals (ALNY): Investor Outlook with a 41% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Feb 02, 2026
pulisher
Feb 02, 2026

Should You Buy Alnylam Pharmaceuticals Before Feb. 12? - AOL.com

Feb 02, 2026
pulisher
Feb 02, 2026

25,451 Shares in Alnylam Pharmaceuticals, Inc. $ALNY Purchased by Mediolanum International Funds Ltd - MarketBeat

Feb 02, 2026
pulisher
Jan 31, 2026

Analyst Views Diverge as Alnylam Pharmaceuticals, Inc. (ALNY) Targets $5.1B Revenue and Long-Term Growth - Insider Monkey

Jan 31, 2026
pulisher
Jan 31, 2026

Alnylam Pharmaceuticals (ALNY) Valuation Check After Recent Share Price Weakness - Yahoo Finance

Jan 31, 2026
pulisher
Jan 31, 2026

Alnylam Pharmaceuticals (ALNY) Receives Analyst Rating Update fr - GuruFocus

Jan 31, 2026
pulisher
Jan 30, 2026

Has The Recent Pullback In Alnylam Pharmaceuticals (ALNY) Opened A Valuation Opportunity? - simplywall.st

Jan 30, 2026
pulisher
Jan 30, 2026

Morgan Stanley Issues Pessimistic Forecast for Alnylam Pharmaceuticals (NASDAQ:ALNY) Stock Price - MarketBeat

Jan 30, 2026
pulisher
Jan 30, 2026

ALNY: Morgan Stanley Adjusts Price Target Amidst Equal-Weight Ra - GuruFocus

Jan 30, 2026
pulisher
Jan 30, 2026

H.C. Wainwright raises Alnylam Pharmaceuticals stock price target on TTR franchise potential - Investing.com Canada

Jan 30, 2026
pulisher
Jan 30, 2026

Bank of America Issues Pessimistic Forecast for Alnylam Pharmaceuticals (NASDAQ:ALNY) Stock Price - MarketBeat

Jan 30, 2026
pulisher
Jan 30, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Given New $510.00 Price Target at HC Wainwright - MarketBeat

Jan 30, 2026
pulisher
Jan 30, 2026

HC Wainwright & Co. Maintains Buy Rating on ALNY, Lowers Price T - GuruFocus

Jan 30, 2026
pulisher
Jan 30, 2026

Alnylam Pharmaceuticals projects 2026 revenue around $5.3 billion as it focuses on a new five-year strategy - MSN

Jan 30, 2026
pulisher
Jan 29, 2026

What analysts say about Alnylam Pharmaceuticals Inc. stockGold Moves & Safe Swing Trade Setups - Mfd.ru

Jan 29, 2026
pulisher
Jan 29, 2026

Alnylam Pharmaceuticals Projects 2026 Revenue Around $5.3 Billion as It Focuses on a New Five-Year Strategy - Finviz

Jan 29, 2026
pulisher
Jan 29, 2026

What Alnylam Pharmaceuticals (ALNY)'s Analyst Re-Rating on Amvuttra and Pipeline Prospects Means For Shareholders - simplywall.st

Jan 29, 2026
pulisher
Jan 29, 2026

Alnylam to Webcast Conference Call Discussing Fourth Quarter and Full Year 2025 Financial Results - Business Wire

Jan 29, 2026
pulisher
Jan 29, 2026

Whale Trades: Should I hold or sell Alnylam Pharmaceuticals Inc nowWeekly Profit Summary & Long Hold Capital Preservation Plans - baoquankhu1.vn

Jan 29, 2026
pulisher
Jan 28, 2026

Barclays Initiates Coverage on Alnylam Pharmaceuticals (ALNY) wi - GuruFocus

Jan 28, 2026
pulisher
Jan 28, 2026

Street Watch: Does Alnylam Pharmaceuticals Inc have a sustainable dividendQuarterly Investment Review & Stock Portfolio Risk Control - baoquankhu1.vn

Jan 28, 2026
pulisher
Jan 28, 2026

J. Safra Sarasin Holding AG Has $4.34 Million Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 28, 2026
pulisher
Jan 28, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Earns Overweight Rating from Analysts at Barclays - MarketBeat

Jan 28, 2026
pulisher
Jan 28, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Fits the 'Affordable Growth' GARP Profile - Chartmill

Jan 28, 2026
pulisher
Jan 28, 2026

Federated Hermes Inc. Boosts Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 28, 2026
pulisher
Jan 28, 2026

Alnylam Pharmaceuticals Q4 2025 Earnings Outlook - Intellectia AI

Jan 28, 2026
pulisher
Jan 27, 2026

Wells Fargo Raises Alnylam (ALNY) Revenue Estimates for Amvuttra Despite Projected Margin Compression - Finviz

Jan 27, 2026
pulisher
Jan 27, 2026

Aug Shorts: Is Alnylam Pharmaceuticals Inc impacted by rising rates2025 Earnings Impact & Safe Investment Capital Preservation Plans - baoquankhu1.vn

Jan 27, 2026
pulisher
Jan 27, 2026

EFG Asset Management North America Corp. Trims Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 27, 2026
pulisher
Jan 27, 2026

What are analysts’ price targets for Alnylam Pharmaceuticals Inc.Weekly Gains Summary & Stepwise Entry and Exit Trade Signals - mfd.ru

Jan 27, 2026
pulisher
Jan 26, 2026

The Five Minute Read - Lowell Sun

Jan 26, 2026
pulisher
Jan 26, 2026

Mitsubishi UFJ Trust & Banking Corp Sells 8,273 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 26, 2026
pulisher
Jan 26, 2026

Wealth Enhancement Advisory Services LLC Boosts Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Jan 26, 2026
pulisher
Jan 25, 2026

A Look At Alnylam Pharmaceuticals (ALNY) Valuation As 2026 Revenue Guidance Signals Strong Growth Potential - simplywall.st

Jan 25, 2026
pulisher
Jan 25, 2026

Alnylam Pharmaceuticals, Inc.'s (NASDAQ:ALNY) Popularity With Investors Is Under Threat From Overpricing - 富途牛牛

Jan 25, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
biotechnology ONC
$351.27
price down icon 0.61%
$834.55
price up icon 0.17%
$148.43
price down icon 0.08%
$109.38
price up icon 0.41%
$98.84
price down icon 1.21%
Cap:     |  Volume (24h):