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Alnylam Pharmaceuticals Inc stock is traded at $312.78, with a volume of 1.09M. It is up +3.68% in the last 24 hours and up +9.32% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
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Previous Close:
$301.67
Open:
$303.87
24h Volume:
1.09M
Relative Volume:
0.97
Market Cap:
$41.76B
Revenue:
$4.29B
Net Income/Loss:
$577.22M
P/E Ratio:
74.32
EPS:
4.2086
Net Cash Flow:
$641.34M
1W Performance:
+6.69%
1M Performance:
+9.32%
6M Performance:
-21.84%
1Y Performance:
-5.15%
1-Day Range:
Value
$303.00
$317.17
1-Week Range:
Value
$290.37
$317.17
52-Week Range:
Value
$273.11
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,500
Name
Twitter
@alnylam
Name
Next Earnings Date
2026-07-30
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY vs VRTX, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
312.78 40.19B 4.29B 577.22M 641.34M 4.2086
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
528.04 126.07B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
654.27 65.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
939.68 57.70B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
189.24 39.82B 742.00K -1.37B -1.07B -7.0731

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-16-26 Downgrade Jefferies Buy → Hold
Jan-28-26 Resumed Barclays Overweight
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
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Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
Jul 02, 2026

Komodo Expands Strategic Partnership with Alnylam Pharmaceuticals, Inc. (ALNY) - Yahoo Finance

Jul 02, 2026
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Jul 01, 2026

July 2026's Top Stocks Estimated To Be Trading Below Their Intrinsic Value - simplywall.st

Jul 01, 2026
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Jul 01, 2026

How Investors May Respond To Alnylam Pharmaceuticals (ALNY) Expanding Its Enterprise-Wide AI Analytics Partnership - simplywall.st

Jul 01, 2026
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Jun 30, 2026

A Quick Look at Today's Ratings for Alnylam Pharmaceuticals(ALNY.US), With a Forecast Between $370 to $527 - Moomoo

Jun 30, 2026
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Jun 30, 2026

Canaccord reiterates Alnylam stock Buy rating after RNAi event By Investing.com - Investing.com Canada

Jun 30, 2026
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Jun 29, 2026

Is Alnylam Pharmaceuticals (ALNY) Undervalued Following Its Expanded Komodo Health AI Partnership? - simplywall.st

Jun 29, 2026
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Jun 29, 2026

ALNY Maintains Buy Rating -- Price Target Lowered by HC Wainwrig - GuruFocus

Jun 29, 2026
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Jun 29, 2026

H.C. Wainwright cuts Alnylam stock price target to $470 on revenue estimates - Investing.com Canada

Jun 29, 2026
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Jun 29, 2026

Barclays Maintains Alnylam Pharmaceuticals(ALNY.US) With Buy Rating, Maintains Target Price $527 - Moomoo

Jun 29, 2026
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Jun 27, 2026

Number of shareholders of Alnylam Pharmaceuticals, Inc – BX:DUL - TradingView

Jun 27, 2026
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Jun 27, 2026

Price to sales forward of Alnylam Pharmaceuticals, Inc. – NASDAQ:ALNY - TradingView

Jun 27, 2026
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Jun 26, 2026

Enterprise value to EBITDA forward of Alnylam Pharmaceuticals, Inc. – NASDAQ:ALNY - TradingView

Jun 26, 2026
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Jun 26, 2026

Alnylam Pharmaceuticals, Inc Actuals & Estimates (NASDAQ:ALNY) - TradingView

Jun 26, 2026
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Jun 26, 2026

Alnylam Pharmaceuticals unveils 2030 targets, betting on AMVUTTRA and pipeline readouts - MSN

Jun 26, 2026
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Jun 25, 2026

Biopharma bites: Ionis' rare disease deal, Vaxart's COVID-19 funding, Alnylam's AI embrace and more from Definium - FirstWord Pharma

Jun 25, 2026
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Jun 25, 2026

Enterprise value to EBIT forward of Alnylam Pharmaceuticals, Inc. – NASDAQ:ALNY - TradingView

Jun 25, 2026
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Jun 25, 2026

ALNY Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
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Jun 25, 2026

Alnylam Pharmaceuticals, Inc Shs Unsponsored Brazilian Depository Receipt Repr 0.05 Sh - TradingView

Jun 25, 2026
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Jun 25, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Discusses ALN-6400 RNAi Therapy Targeting Plasminogen for Rare Bleeding DisordersSlideshow (NASDAQ:ALNY) 2026-06-25 - Seeking Alpha

Jun 25, 2026
pulisher
Jun 25, 2026

Komodo Health Expands Strategic Partnership with Alnylam Pharmaceuticals to Scale Marmot Analytics Ai Platform - marketscreener.com

Jun 25, 2026
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Jun 25, 2026

Alnylam Pharmaceuticals Inc RNAi Roundtable Webcast Transcript - GuruFocus

Jun 25, 2026
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Jun 25, 2026

Price to earnings forward of Alnylam Pharmaceuticals, Inc. – NASDAQ:ALNY - TradingView

Jun 25, 2026
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Jun 25, 2026

Komodo Expands Strategic Partnership With Alnylam to Scale AI-Powered Intelligence Platform - Business Wire

Jun 25, 2026
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Jun 25, 2026

Oppenheimer Maintains Alnylam Pharmaceuticals(ALNY.US) With Buy Rating, Maintains Target Price $500 - Moomoo

Jun 25, 2026
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Jun 25, 2026

Alnylam Pharmaceuticals (ALNY) Short Interest & Short Float | Updated Jun 2026 $ALNY - MarketBeat

Jun 25, 2026
pulisher
Jun 24, 2026

Why (ALNY) Price Action Is Critical for Tactical Trading - Stock Traders Daily

Jun 24, 2026
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Jun 24, 2026

Morgan Stanley Maintains Alnylam Pharmaceuticals(ALNY.US) With Hold Rating, Maintains Target Price $370 - Moomoo

Jun 24, 2026
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Jun 24, 2026

AI-Driven RNAi Push and Nordic Expansion Might Change The Case For Investing In Alnylam (ALNY) - simplywall.st

Jun 24, 2026
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Jun 23, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) and GENESIS Pharma Expand Commercial Partnership - Insider Monkey

Jun 23, 2026
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Jun 23, 2026

Alnylam Pharmaceuticals (ALNY), Inceptive Form $2B Partnership to Advance RNAi Drug Discovery - Yahoo Finance

Jun 23, 2026
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Jun 23, 2026

Regeneron gets US, EU review for myasthenia gravis drug (REGN) - Seeking Alpha

Jun 23, 2026
pulisher
Jun 23, 2026

Here's How Much $100 Invested In Alnylam Pharmaceuticals 10 Years Ago Would Be Worth Today - Sahm

Jun 23, 2026
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Jun 22, 2026

Dyne Therapeutics adds ex-Sage CEO Barry Greene to board - Stock Titan

Jun 22, 2026
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Jun 22, 2026

Alnylam (ALNY) Expands Its RNAi Therapeutics Reach Into Four More Nordic Countries - Insider Monkey

Jun 22, 2026
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Jun 22, 2026

Alnylam Pharmaceuticals Inc (NASDAQ:ALNY) Passes the "Little Book" Test with Explosive Growth and Upward Momentum - ChartMill

Jun 22, 2026
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Jun 22, 2026

Can Alnylam's Broader Portfolio Ease Its Dependence on Amvuttra? - Yahoo Finance

Jun 22, 2026
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Jun 22, 2026

Alnylam Pharmaceuticals (ALNY) Investor Outlook: A Biotech Leader with 56.90% Upside Potential - DirectorsTalk Interviews

Jun 22, 2026
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Jun 20, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Partners with Inceptive Nucleics to Accelerate Growth as A High-Growth Large-Cap Stock - Insider Monkey

Jun 20, 2026
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Jun 19, 2026

ALNYLAM PHARMACEUTICALS INC (NASDAQ:ALNY): A Decent Value Play with Strong Growth at a Discount to Peers - ChartMill

Jun 19, 2026
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Jun 17, 2026

Alnylam Pharmaceuticals Inc (ALNY) Institutional Confidence - TradingKey

Jun 17, 2026
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Jun 17, 2026

Alnylam Pharmaceuticals Inc (ALNY) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Alnylam Pharmaceuticals Inc (ALNY) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
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Jun 17, 2026

Alnylam Pharmaceuticals Inc (ALNY) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 17, 2026
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Jun 17, 2026

Alnylam Pharmaceuticals Inc - TradingKey

Jun 17, 2026
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Jun 16, 2026

Does Alnylam’s Generative AI Pact With Inceptive Nucleics Redraw The R&D Bull Case For ALNY? - simplywall.st

Jun 16, 2026
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Jun 16, 2026

Analysts Offer Insights on Healthcare Companies: MBX Biosciences, Inc. (MBX) and Alnylam Pharma (ALNY) - The Globe and Mail

Jun 16, 2026
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Jun 14, 2026

Alnylam expands Genesis Pharma collaboration in Europe - MSN

Jun 14, 2026
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Jun 14, 2026

Alnylam Taps Generative AI And Nordic Expansion As Market Lags Targets - Yahoo Finance

Jun 14, 2026
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Jun 13, 2026

Understanding Momentum Shifts in (ALNY) - Stock Traders Daily

Jun 13, 2026
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Jun 13, 2026

Alnylam Pharmaceuticals stock hits 52-week low at $282.71 By Investing.com - Investing.com Nigeria

Jun 13, 2026
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Jun 12, 2026

Alnylam Pharmaceuticals stock hits 52-week low at $282.71 - Investing.com

Jun 12, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Alnylam Pharmaceuticals Inc Stock (ALNY) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
PYOTT DAVID E I
Director
Jun 01 '26
Sale
299.18
3,830
1,145,853
1,582
$189.24
price up icon 0.92%
$79.76
price up icon 10.01%
ONC ONC
$297.65
price up icon 2.38%
$57.77
price up icon 3.57%
$35.13
price up icon 0.29%
Cap:     |  Volume (24h):