456.04
price up icon1.44%   6.48
after-market After Hours: 456.04
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Alnylam Pharmaceuticals Inc stock is traded at $456.04, with a volume of 1.82M. It is up +1.44% in the last 24 hours and up +0.01% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$449.56
Open:
$449
24h Volume:
1.82M
Relative Volume:
1.52
Market Cap:
$59.78B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,896.22
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
-1.59%
1M Performance:
+0.01%
6M Performance:
+73.24%
1Y Performance:
+71.06%
1-Day Range:
Value
$441.22
$459.77
1-Week Range:
Value
$436.51
$485.36
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
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ALNY
Alnylam Pharmaceuticals Inc
456.04 58.93B 3.21B 43.57M 221.36M 0.2405
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VRTX
Vertex Pharmaceuticals Inc
425.57 107.66B 11.39B 3.64B 3.50B 13.99
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REGN
Regeneron Pharmaceuticals Inc
651.80 68.74B 14.25B 4.58B 3.88B 41.77
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ARGX
Argen X Se Adr
818.50 50.51B 3.06B 1.28B 447.35M 19.67
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INSM
Insmed Inc
189.60 41.29B 447.02M -1.18B -868.57M -6.1812

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
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Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
12:11 PM

How risky is Alnylam Pharmaceuticals Inc. (DUL) stock compared to peersEarnings Overview Report & Precise Buy Zone Tips - newser.com

12:11 PM
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Nov 02, 2025

Can Alnylam Pharmaceuticals Inc. (DUL) stock sustain revenue momentum2025 Stock Rankings & Long-Term Safe Investment Plans - newser.com

Nov 02, 2025
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Nov 02, 2025

Using data filters to optimize entry into Alnylam Pharmaceuticals Inc.July 2025 Drop Watch & Stepwise Trade Execution Plans - newser.com

Nov 02, 2025
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Nov 02, 2025

What RSI levels show for Alnylam Pharmaceuticals Inc. (DUL) stockWeekly Investment Report & Safe Entry Point Identification - newser.com

Nov 02, 2025
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Nov 02, 2025

Is Alnylam Pharmaceuticals Inc. reversing from oversold territoryEarnings Beat & Risk Controlled Swing Trade Alerts - newser.com

Nov 02, 2025
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Nov 02, 2025

Combining machine learning predictions for Alnylam Pharmaceuticals Inc.Earnings Performance Report & Growth Focused Stock Reports - newser.com

Nov 02, 2025
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Nov 02, 2025

Alnylam Pharmaceuticals Hits Day Low of $436.51 Amid Price Pressure - Markets Mojo

Nov 02, 2025
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Nov 02, 2025

Alnylam Pharmaceuticals, Inc. Beat Analyst Estimates: See What The Consensus Is Forecasting For Next Year - Yahoo Finance

Nov 02, 2025
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Nov 02, 2025

Benzinga's 'Stock Whisper' Index: 5 Stocks Investors Secretly Monitor But Don't Talk About Yet - Benzinga

Nov 02, 2025
pulisher
Nov 02, 2025

ANTIPODES PARTNERS Ltd Sells 36,750 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Is Alnylam Pharmaceuticals Inc. (DUL) stock vulnerable to rate hikes2025 Technical Overview & High Accuracy Trade Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Strs Ohio Has $9.83 Million Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Focus Partners Advisor Solutions LLC Has $263,000 Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Receives Average Rating of "Moderate Buy" from Analysts - MarketBeat

Nov 02, 2025
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Nov 02, 2025

Can Alnylam Pharmaceuticals Inc. (DUL) stock sustain institutional flows2025 Trading Recap & Growth Oriented Trade Recommendations - newser.com

Nov 02, 2025
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Nov 02, 2025

What data driven models say about Alnylam Pharmaceuticals Inc.’s futureMarket Growth Review & Free Community Consensus Stock Picks - newser.com

Nov 02, 2025
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Nov 02, 2025

Why Alnylam Pharmaceuticals Inc. stock is recommended by analystsJuly 2025 Review & Capital Efficiency Focused Strategies - newser.com

Nov 02, 2025
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Nov 02, 2025

How dovish Fed policy supports Alnylam Pharmaceuticals Inc. (DUL) stockEarnings Risk Summary & Weekly Setup with High ROI Potential - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Q3 2025 Earnings Call Transcript - Insider Monkey

Nov 02, 2025
pulisher
Nov 02, 2025

A Fresh Look at Alnylam Pharmaceuticals (ALNY) Valuation Following Q3 Profit Surge and Upgraded Guidance - simplywall.st

Nov 02, 2025
pulisher
Nov 01, 2025

Is Alnylam Pharmaceuticals Inc. stock dividend yield sustainableJuly 2025 Institutional & High Conviction Buy Zone Picks - newser.com

Nov 01, 2025
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Nov 01, 2025

Piper Sandler Reiterates "Overweight" Rating for Alnylam Pharmaceuticals (NASDAQ:ALNY) - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Raised to $527.00 at Barclays - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Evercore ISI Sticks to Their Buy Rating for Alnylam Pharma (ALNY) - The Globe and Mail

Nov 01, 2025
pulisher
Nov 01, 2025

Is Alnylam Pharmaceuticals Inc. (DUL) stock overpriced at current multiplesJuly 2025 Trends & Growth Oriented Trade Recommendations - newser.com

Nov 01, 2025
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Nov 01, 2025

How to monitor Alnylam Pharmaceuticals Inc. with trend dashboards2025 Macro Impact & Short-Term High Return Strategies - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Alnylam Announces Interim Phase 1 Data of Nucresiran (ALN-TTRsc04) Showing Rapid Knockdown of TTR that is Sustained at Six Months Following a Single Dose - ADVFN

Nov 01, 2025
pulisher
Nov 01, 2025

Alnylam Announces U.S. Food and Drug Administration Acceptance of Supplemental New Drug Application for Vutrisiran for the Treatment of ATTR Amyloidosis with Cardiomyopathy - ADVFN

Nov 01, 2025
pulisher
Nov 01, 2025

Howard Capital Management Inc. Makes New $271,000 Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Will Alnylam Pharmaceuticals Inc. continue its uptrendIndex Update & Community Shared Stock Ideas - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

How Alnylam's Raised 2025 Revenue Outlook and AMVUTTRA Uptake Will Impact ALNY Investors - Yahoo Finance

Nov 01, 2025
pulisher
Oct 31, 2025

Alnylam Pharmaceuticals (ALNY) Profitability Milestone Reinforces Bull Case Ahead of Forecasted 52% Earnings Growth - simplywall.st

Oct 31, 2025
pulisher
Oct 31, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Shares Gap Down on Analyst Downgrade - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Jefferies Financial Group Lowers Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target to $549.00 - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Announces Earnings Results - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Alnylam Pharmaceuticals: Q3 Earnings ReviewA Sensational Year Reaches Its Peak (ALNY) - Seeking Alpha

Oct 31, 2025
pulisher
Oct 31, 2025

Alnylam Pharmaceuticals (ALNY US): On Track for S&P500 Inclusion Following Positive Earnings - Smartkarma

Oct 31, 2025
pulisher
Oct 31, 2025

ALNY: Piper Sandler Raises Price Target Amid Overweight Rating | - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

ALNY Q3 Earnings and Revenues Top Estimates on Higher Amvuttra Sales - sharewise.com

Oct 31, 2025
pulisher
Oct 31, 2025

Barclays Raises Price Target for Alnylam Pharmaceuticals (ALNY) to $527 | ALNY Stock News - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

Strong Demand for Narrow-Moat Alnylam's Amvuttra Drives Growth; Pipeline Continues to Make Progress - Morningstar

Oct 31, 2025
pulisher
Oct 31, 2025

Jennison Associates LLC Has $114.15 Million Stock Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Alnylam: Q3 Earnings Snapshot - Stamford Advocate

Oct 31, 2025
pulisher
Oct 31, 2025

How to recover losses in Alnylam Pharmaceuticals Inc. stockJuly 2025 Closing Moves & Advanced Swing Trade Entry Alerts - newser.com

Oct 31, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$651.80
price down icon 0.34%
$818.50
price down icon 0.23%
$189.60
price down icon 2.38%
biotechnology ONC
$310.48
price up icon 0.73%
$103.91
price down icon 0.73%
Cap:     |  Volume (24h):