464.56
price down icon1.84%   -8.73
after-market After Hours: 465.34 0.78 +0.17%
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Alnylam Pharmaceuticals Inc stock is traded at $464.56, with a volume of 671.99K. It is down -1.84% in the last 24 hours and up +9.70% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$473.29
Open:
$472.67
24h Volume:
671.99K
Relative Volume:
0.62
Market Cap:
$61.37B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,931.64
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
+4.37%
1M Performance:
+9.70%
6M Performance:
+52.16%
1Y Performance:
+82.38%
1-Day Range:
Value
$464.56
$477.06
1-Week Range:
Value
$444.43
$479.79
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
464.56 62.53B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
457.26 117.50B 11.74B 3.68B 3.34B 14.19
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REGN
Regeneron Pharmaceuticals Inc
722.83 76.06B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
916.31 56.75B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
205.04 44.10B 447.02M -1.18B -906.14M -6.1812

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
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Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

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Alnylam Pharmaceuticals (ALNY): Is the Stock’s Recent Surge Justified by Its Valuation? - simplywall.st

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How Alnylam Pharmaceuticals Inc. stock benefits from tech adoption2025 Technical Overview & Risk Adjusted Buy/Sell Alerts - Newser

04:48 AM
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Dec 03, 2025

Alnylam Pharmaceuticals Announces Changes to Board of Directors - PharmiWeb.com

Dec 03, 2025
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Dec 03, 2025

Alnylam Pharmaceuticals announces changes to board of directors - marketscreener.com

Dec 03, 2025
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Dec 03, 2025

Alnylam announces board changes, appoints Stuart Arbuckle as director By Investing.com - Investing.com India

Dec 03, 2025
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Quadrature Capital Ltd Trims Stake in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 03, 2025
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Will Alnylam Pharmaceuticals Inc. (DUL) stock boost dividends furtherJuly 2025 Macro Moves & Free Expert Verified Stock Movement Alerts - Newser

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How Alnylam Pharmaceuticals Inc. (DUL) stock reacts to fiscal policies2025 Bull vs Bear & Smart Allocation Stock Reports - Newser

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Dec 03, 2025
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Here's How Much You Would Have Made Owning Alnylam Pharmaceuticals Stock In The Last 20 Years - Benzinga

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Options Movement At Alnylam Pharmaceuticals: Yvonne Greenstreet Exercises Worth $1.72M - Benzinga

Dec 02, 2025
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Can Alnylam Pharmaceuticals Inc. (DUL) stock sustain revenue momentumMarket Movement Recap & AI Powered Market Entry Strategies - Newser

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Is Alnylam Pharmaceuticals Inc. (DUL) stock good for wealth creationJuly 2025 Catalysts & High Accuracy Swing Trade Signals - Newser

Dec 02, 2025
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CRH, Vertiv, Ares, Alnylam Could Be Added to S&P 500 Friday in Rebalancing - Barron's

Dec 01, 2025
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Spotlight On Alnylam Pharmaceuticals And 2 Other Stocks Possibly Trading Below Fair Value - Yahoo Finance

Dec 01, 2025
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Nov 29, 2025

Alnylam Pharmaceuticals, Inc. (0HD2.L) Stock Price, News, Quote & History - Yahoo! Finance Canada

Nov 29, 2025
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Nov 28, 2025

The Bull Case For Alnylam Pharmaceuticals (ALNY) Could Change Following Raised Sales Guidance for Vutrisiran - simplywall.st

Nov 28, 2025
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What's Going On With Alnylam Stock On Friday? - Benzinga

Nov 28, 2025
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Can Alnylam Pharmaceuticals Inc. stock beat market expectations this quarterWeekly Earnings Recap & Technical Confirmation Trade Alerts - moha.gov.vn

Nov 28, 2025
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Nov 28, 2025

Alnylam Pharmaceuticals Reports Strong TTR Growth Amid Challenges - MSN

Nov 28, 2025
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Nov 27, 2025

IPO Launch: Why Alnylam Pharmaceuticals Inc. stock could be next big winnerMarket Risk Analysis & High Conviction Buy Zone Alerts - moha.gov.vn

Nov 27, 2025
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Nov 27, 2025

ETFs Investing in Alnylam Pharmaceuticals, Inc Stocks - TradingView

Nov 27, 2025
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Nov 27, 2025

Thanksgiving: Top 10 Most Innovative BioPharma Drugs In Phase 3 - Seeking Alpha

Nov 27, 2025
pulisher
Nov 27, 2025

A Look at Alnylam Pharmaceuticals's Valuation Following Raised Sales Guidance on Vutrisiran Outperformance - simplywall.st

Nov 27, 2025
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Nov 26, 2025

Here’s What Boosted Alnylam Pharmaceuticals (ALNY) in Q3 - MSN

Nov 26, 2025
pulisher
Nov 26, 2025

Backdoor AI Beneficiary Yields 8.8%, Trades at 13% Discount - Investing.com

Nov 26, 2025
pulisher
Nov 26, 2025

Alnylam’s TTR Franchise Drives Big Revenue Growth And Raises Guidance - Finimize

Nov 26, 2025
pulisher
Nov 25, 2025

MoA Mid Cap Growth Fund's Alnylam Pharmaceuticals Inc(ALNY) Holding History - GuruFocus

Nov 25, 2025
pulisher
Nov 24, 2025

Alnylam Pharmaceuticals (ALNY): Assessing Valuation After Recent Share Price Pullback - Yahoo Finance

Nov 24, 2025
pulisher
Nov 24, 2025

Is Alnylam Pharmaceuticals Stock Justified After 73.9% Surge and Clinical Trial Milestones? - simplywall.st

Nov 24, 2025
pulisher
Nov 24, 2025

Small Interfering RNA (siRNA) Therapeutics Market 2025: - openPR.com

Nov 24, 2025
pulisher
Nov 21, 2025

Here's How Much You Would Have Made Owning Alnylam Pharmaceuticals Stock In The Last 15 Years - Benzinga

Nov 21, 2025
pulisher
Nov 21, 2025

Alnylam's ATTR cardiomyopathy drug backed for NHS use - pharmaphorum

Nov 21, 2025
pulisher
Nov 21, 2025

NICE Final Draft Guidance backs Alnylam’s Amvuttra - The Pharma Letter

Nov 21, 2025
pulisher
Nov 21, 2025

Why Alnylam Pharmaceuticals Inc. (DUL) stock attracts wealthy investorsJuly 2025 Institutional & Expert Approved Trade Ideas - newser.com

Nov 21, 2025
pulisher
Nov 20, 2025

Alnylam Pharmaceuticals Faces Weak Start with 6.56% Gap Down Amid Market Concerns - Markets Mojo

Nov 20, 2025
pulisher
Nov 20, 2025

UK's drug-cost watchdog recommends Alnylam's heart disease drug - Reuters

Nov 20, 2025
pulisher
Nov 20, 2025

UK’s drug-cost watchdog recommends Alnylam’s heart disease drug - The Mighty 790 KFGO

Nov 20, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$916.31
price down icon 0.60%
$722.83
price down icon 0.12%
$205.04
price down icon 0.84%
biotechnology ONC
$331.27
price down icon 1.95%
$95.99
price down icon 0.77%
Cap:     |  Volume (24h):