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Agios Pharmaceuticals Inc stock is traded at $27.59, with a volume of 551.72K. It is up +0.48% in the last 24 hours and down -0.53% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236, and others.
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Previous Close:
$27.45
Open:
$27.34
24h Volume:
551.72K
Relative Volume:
0.38
Market Cap:
$1.61B
Revenue:
$32.87M
Net Income/Loss:
$674.31M
P/E Ratio:
2.4283
EPS:
11.36
Net Cash Flow:
$-330.11M
1W Performance:
+0.92%
1M Performance:
-0.53%
6M Performance:
-23.53%
1Y Performance:
-17.76%
1-Day Range:
Value
$27.10
$27.67
1-Week Range:
Value
$26.54
$27.67
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
488
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
AGIO
Agios Pharmaceuticals Inc
27.58 1.60B 32.87M 674.31M -330.11M 11.36
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
467.92 113.87B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
773.55 80.22B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
405.75 52.56B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
801.69 49.31B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
174.75 37.37B 447.02M -1.18B -906.14M -6.1812

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
01:48 AM

JP Morgan Raises Price Target for Agios Pharmaceuticals (AGIO) to $25 | AGIO Stock News - GuruFocus

01:48 AM
pulisher
Jan 05, 2026

Agios to Present at the 44th Annual J.P. Morgan Healthcare Conference on January 14, 2026 - The Manila Times

Jan 05, 2026
pulisher
Jan 02, 2026

Insider Selling: Agios Pharmaceuticals (NASDAQ:AGIO) Insider Sells 2,932 Shares of Stock - MarketBeat

Jan 02, 2026
pulisher
Jan 02, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) CFO Sells $79,427.88 in Stock - MarketBeat

Jan 02, 2026
pulisher
Jan 02, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) CEO Brian Goff Sells 18,703 Shares - MarketBeat

Jan 02, 2026
pulisher
Jan 02, 2026

Agios pharma chief legal officer Burns sells $79k in stock - Investing.com Canada

Jan 02, 2026
pulisher
Jan 02, 2026

Agios pharma chief medical officer Gheuens sells $79k in stock - Investing.com Canada

Jan 02, 2026
pulisher
Jan 02, 2026

Agios Pharmaceuticals CEO Goff sells $506,663 in stock By Investing.com - Investing.com Australia

Jan 02, 2026
pulisher
Jan 02, 2026

Agios Pharmaceuticals CEO Goff sells $506,663 in stock - Investing.com

Jan 02, 2026
pulisher
Jan 02, 2026

Jones Cecilia, Agios Pharmaceuticals CFO, sells $79k in stock By Investing.com - Investing.com UK

Jan 02, 2026
pulisher
Jan 02, 2026

Agios pharma CCO Milanova sells $79k in stock after option exercise - Investing.com UK

Jan 02, 2026
pulisher
Jan 01, 2026

Agios Pharma shares jump 16% as US FDA expands approval for blood disorder drug - MSN

Jan 01, 2026
pulisher
Jan 01, 2026

Momentum Indicator Shows Bearish Divergence in Sylvan Plyboard India LimitedRisk-Reward Ratio Analysis & Stay Ahead With Daily Market Discussions - earlytimes.in

Jan 01, 2026
pulisher
Jan 01, 2026

How Agios Pharmaceuticals Inc. stock valuations compare to rivalsStock Correlation Metrics & Free Superior Profit Margins - bollywoodhelpline.com

Jan 01, 2026
pulisher
Dec 30, 2025

Agios Pharma jumps 15% as FDA expands use of anaemia drug mitapivat - MSN

Dec 30, 2025
pulisher
Dec 28, 2025

Geopolitics Watch: Is Agios Pharmaceuticals Inc 8AP stock attractive post correctionLayoff News & Low Risk Entry Point Tips - moha.gov.vn

Dec 28, 2025
pulisher
Dec 27, 2025

FDA approves Agios’ AQVESME (mitapivat) for the treatment of anemia in adults - MSN

Dec 27, 2025
pulisher
Dec 26, 2025

Agios Pharmaceuticals (NASDAQ:AGIO) Shares Down 5.3%Should You Sell? - MarketBeat

Dec 26, 2025
pulisher
Dec 26, 2025

Capital One Financial To Rally More Than 24%? Here Are Top Analyst Forecasts For Friday - Benzinga

Dec 26, 2025
pulisher
Dec 26, 2025

AGIO: Analyst Andrew Berens Raises Agios Pharmaceuticals Price T - GuruFocus

Dec 26, 2025
pulisher
Dec 26, 2025

Agios Pharmaceuticals (AGIO) Surges 18.6%: Is This an Indication of Further Gains? - Yahoo Finance

Dec 26, 2025
pulisher
Dec 26, 2025

BofA Securities raises Agios Pharma stock price target on FDA approval - Investing.com India

Dec 26, 2025
pulisher
Dec 25, 2025

Agios (AGIO) Gets 18.6% Boost from Aqvesme OK - Finviz

Dec 25, 2025
pulisher
Dec 25, 2025

B of A Securities Maintains Agios Pharmaceuticals (AGIO) Buy Recommendation - MSN

Dec 25, 2025
pulisher
Dec 25, 2025

Agios Pharmaceuticals price target raised to $34 from $32 at BofA - Yahoo Finance

Dec 25, 2025
pulisher
Dec 25, 2025

Agios Stock (+19%): AQVESME Thalassemia Approval Ignites Re-Rate - Trefis

Dec 25, 2025
pulisher
Dec 24, 2025

Agios Pharma shares jump as US FDA expands approval for blood disorder drug - wibqam.com

Dec 24, 2025
pulisher
Dec 24, 2025

Why Agios Pharmaceuticals (AGIO) Is Up 14.6% After First-in-Class Thalassemia Drug AQVESME Wins FDA Approval - Sahm

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharma stock price target raised to $62 from $48 at H.C. Wainwright - Investing.com India

Dec 24, 2025
pulisher
Dec 24, 2025

Truist Financial Forecasts Strong Price Appreciation for Agios Pharmaceuticals (NASDAQ:AGIO) Stock - MarketBeat

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharma Stock: A Buy After FDA Approves Aqvesme (NASDAQ:AGIO) - Seeking Alpha

Dec 24, 2025
pulisher
Dec 24, 2025

Here's Why Shares in Agios Pharmaceuticals Popped Today - AOL.com

Dec 24, 2025
pulisher
Dec 24, 2025

12 Health Care Stocks Moving In Wednesday's Intraday Session - Benzinga

Dec 24, 2025
pulisher
Dec 24, 2025

Here's Why Shares in Agios Pharmaceuticals Popped Today - The Motley Fool

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharmaceuticals, Inc. (AGIO) Discusses FDA Approval of AQVESME for Anemia in Alpha and Beta ThalassemiaSlideshow (NASDAQ:AGIO) 2025-12-24 - Seeking Alpha

Dec 24, 2025
pulisher
Dec 24, 2025

First oral anemia treatment across thalassaemia types approved in USA - The Pharma Letter

Dec 24, 2025
pulisher
Dec 24, 2025

AGIO's Mitapivat Gets FDA Nod for Thalassemia Indication with REMS in Label - Eastern Progress

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharma shares jump as US FDA expands approval for its blood disorder drug - Yahoo Finance

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharmaceuticals (NASDAQ:AGIO) Shares Gap Up on Analyst Upgrade - MarketBeat

Dec 24, 2025
pulisher
Dec 24, 2025

The $1.7 Billion Pivot: Agios Pharmaceuticals (AGIO) and the New Frontier of Oral Thalassemia Therapy - FinancialContent

Dec 24, 2025
pulisher
Dec 24, 2025

AGIO (Agios Pharmaceuticals) EV-to-OCF : -1.89 (As of Dec. 24, 2025) - GuruFocus

Dec 24, 2025
pulisher
Dec 24, 2025

Agios (AGIO) Surges 12% Following FDA Approval of New Thalassemi - GuruFocus

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Shares Rise After FDA Approves Aqvesme to Treat Anemia in Thalassemia Patients - marketscreener.com

Dec 24, 2025
pulisher
Dec 24, 2025

Why Did AGIO Stock Surge 14% Today? - Stocktwits

Dec 24, 2025
pulisher
Dec 24, 2025

Agios Pharmaceuticals stock soars after FDA approves AQVESME for thalassemia - Investing.com Canada

Dec 24, 2025
pulisher
Dec 24, 2025

Transcript : Agios Pharmaceuticals, Inc.Special Call - marketscreener.com

Dec 24, 2025
pulisher
Dec 24, 2025

Bank of America Issues Positive Forecast for Agios Pharmaceuticals (NASDAQ:AGIO) Stock Price - MarketBeat

Dec 24, 2025

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Burns James William
Chief Legal Officer
Dec 30 '25
Option Exercise
0.00
6,000
0
34,650
Burns James William
Chief Legal Officer
Dec 30 '25
Sale
27.09
2,932
79,428
31,718
Goff Brian
Chief Executive Officer
Dec 30 '25
Option Exercise
0.00
38,278
0
149,333
Goff Brian
Chief Executive Officer
Dec 30 '25
Sale
27.09
18,703
506,664
136,583
Gheuens Sarah
Chief Medical Officer
Dec 30 '25
Option Exercise
0.00
6,000
0
67,727
Gheuens Sarah
Chief Medical Officer
Dec 30 '25
Sale
27.09
2,932
79,428
64,795
Milanova Tsveta
Chief Commercial Officer
Dec 30 '25
Option Exercise
0.00
6,000
0
32,122
Milanova Tsveta
Chief Commercial Officer
Dec 30 '25
Sale
27.09
2,932
79,428
29,190
Jones Cecilia
Chief Financial Officer
Dec 30 '25
Option Exercise
0.00
6,000
0
40,326
Jones Cecilia
Chief Financial Officer
Dec 30 '25
Sale
27.09
2,932
79,428
37,394
$40.59
price up icon 2.45%
$33.12
price up icon 4.10%
$107.28
price up icon 5.34%
$98.35
price up icon 1.49%
biotechnology ONC
$320.86
price up icon 0.11%
$174.46
price down icon 0.43%
Cap:     |  Volume (24h):