14.98
price down icon2.54%   -0.39
after-market After Hours: 14.86 -0.12 -0.80%
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Denali Therapeutics Inc stock is traded at $14.98, with a volume of 1.19M. It is down -2.54% in the last 24 hours and up +5.57% over the past month. Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
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Previous Close:
$15.37
Open:
$15.42
24h Volume:
1.19M
Relative Volume:
0.63
Market Cap:
$2.19B
Revenue:
$340.81M
Net Income/Loss:
$-419.65M
P/E Ratio:
-5.2561
EPS:
-2.85
Net Cash Flow:
$-402.10M
1W Performance:
-1.58%
1M Performance:
+5.57%
6M Performance:
+17.95%
1Y Performance:
-46.50%
1-Day Range:
Value
$14.98
$15.62
1-Week Range:
Value
$14.85
$16.51
52-Week Range:
Value
$10.57
$33.33

Denali Therapeutics Inc Stock (DNLI) Company Profile

Name
Name
Denali Therapeutics Inc
Name
Phone
(650) 866-8547
Name
Address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO
Name
Employee
486
Name
Twitter
Name
Next Earnings Date
2025-08-08
Name
Latest SEC Filings
Name
DNLI's Discussions on Twitter

Compare DNLI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
DNLI
Denali Therapeutics Inc
14.98 2.25B 340.81M -419.65M -402.10M -2.85
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
407.37 104.55B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
464.95 60.36B 2.46B -319.09M -52.09M -2.4669
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
557.73 59.84B 14.21B 4.46B 3.56B 39.69
Biotechnology icon
ARGX
Argen X Se Adr
799.56 49.07B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ONC
Beone Medicines Ltd Adr
327.03 35.16B 4.56B -176.77M 225.30M -1.7177

Denali Therapeutics Inc Stock (DNLI) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Mar-07-25 Resumed Morgan Stanley Overweight
Feb-11-25 Initiated Deutsche Bank Buy
Jan-07-25 Initiated Robert W. Baird Outperform
Jan-03-25 Initiated William Blair Outperform
Dec-16-24 Upgrade Stifel Hold → Buy
Oct-10-24 Resumed Raymond James Mkt Perform
Oct-07-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-13-23 Initiated Citigroup Buy
Nov-20-23 Resumed JP Morgan Overweight
Oct-24-23 Resumed Cantor Fitzgerald Overweight
Sep-06-23 Initiated B. Riley Securities Buy
Jan-30-23 Initiated SVB Securities Outperform
Dec-05-22 Initiated Cowen Outperform
Nov-02-22 Upgrade BTIG Research Neutral → Buy
Nov-02-22 Initiated BofA Securities Buy
Jun-23-22 Initiated Berenberg Buy
Dec-10-21 Resumed Raymond James Mkt Perform
Sep-21-21 Initiated Oppenheimer Outperform
Sep-01-21 Initiated SMBC Nikko Outperform
May-18-21 Initiated UBS Buy
Feb-26-21 Reiterated H.C. Wainwright Buy
Feb-10-21 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-11-20 Reiterated H.C. Wainwright Buy
Oct-16-20 Downgrade BTIG Research Buy → Neutral
Sep-14-20 Resumed JP Morgan Overweight
Aug-20-20 Reiterated H.C. Wainwright Buy
Mar-13-20 Upgrade Evercore ISI In-line → Outperform
Feb-28-20 Upgrade Wedbush Neutral → Outperform
Feb-24-20 Initiated Jefferies Buy
Feb-19-20 Initiated Stifel Hold
Jan-27-20 Upgrade Goldman Neutral → Buy
Sep-26-19 Initiated Wedbush Neutral
Sep-13-19 Initiated Nomura Buy
Aug-09-19 Initiated BTIG Research Buy
Jun-26-19 Initiated H.C. Wainwright Buy
Nov-15-18 Initiated Cantor Fitzgerald Overweight
Nov-12-18 Initiated Janney Buy
Mar-12-18 Downgrade Evercore ISI Outperform → In-line
Jan-02-18 Initiated Evercore ISI Outperform
Jan-02-18 Initiated Goldman Neutral
Jan-02-18 Initiated JP Morgan Overweight
Jan-02-18 Initiated Morgan Stanley Overweight
View All

Denali Therapeutics Inc Stock (DNLI) Latest News

pulisher
04:02 AM

Denali Therapeutics Announces FDA Review Extension of BLA - GlobeNewswire

04:02 AM
pulisher
04:01 AM

Denali Therapeutics Announces FDA Review Extension of BLA for Tividenofusp Alfa for the Treatment of MPS II (Hunter Syndrome) - Stock Titan

04:01 AM
pulisher
08:07 AM

Will Denali Therapeutics Inc. stock rally after Fed decisionsStop Loss & Capital Protection Trade Alerts - newser.com

08:07 AM
pulisher
Oct 10, 2025

Understanding Denali Therapeutics Inc.’s price movementMarket Risk Analysis & Low Volatility Stock Suggestions - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

How to forecast Denali Therapeutics Inc. trends using time seriesWeekly Trend Summary & Advanced Swing Trade Entry Alerts - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

Can Denali Therapeutics Inc. (4DN) stock resist broad market declinesMarket Weekly Review & Weekly Top Stock Performers List - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

Tick level data insight on Denali Therapeutics Inc. volatilityTrend Reversal & Reliable Volume Spike Alerts - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

Forecasting Denali Therapeutics Inc. price range with options data2025 Year in Review & Fast Entry High Yield Stock Tips - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

What institutional flow reveals about Denali Therapeutics Inc.Quarterly Growth Report & Verified Swing Trading Watchlist - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

Will Denali Therapeutics Inc. bounce back from current supportWeekly Trade Review & High Conviction Buy Zone Alerts - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

Denali Therapeutics' (DNLI) "Sell (D-)" Rating Reaffirmed at Weiss Ratings - MarketBeat

Oct 10, 2025
pulisher
Oct 07, 2025

Is Denali Therapeutics Inc a good long term investmentFinancial Sector Performance & Start Small. End Wealthy. - earlytimes.in

Oct 07, 2025
pulisher
Oct 06, 2025

What the Next Quarters Forecast Means for Beacon Trusteeship Limited InvestorsQuarterly Earnings Review & Free Tools to Find Winning Stocks - earlytimes.in

Oct 06, 2025
pulisher
Oct 06, 2025

Denali Therapeutics Inc 4DN Stock Analysis and ForecastSector Performance Review & Get Free Expert Trading Recommendations - earlytimes.in

Oct 06, 2025
pulisher
Oct 06, 2025

How to monitor Denali Therapeutics Inc. with trend dashboardsJuly 2025 Opening Moves & Consistent Profit Trade Alerts - newser.com

Oct 06, 2025
pulisher
Oct 05, 2025

Regression analysis insights on Denali Therapeutics Inc. performanceBull Run & Consistent Return Strategy Ideas - newser.com

Oct 05, 2025
pulisher
Oct 05, 2025

Should you hold or exit Denali Therapeutics Inc. nowJuly 2025 Institutional & Verified Swing Trading Watchlist - newser.com

Oct 05, 2025
pulisher
Oct 05, 2025

Visual analytics tools that track Denali Therapeutics Inc. performanceTake Profit & Weekly Breakout Stock Alerts - newser.com

Oct 05, 2025
pulisher
Oct 04, 2025

Is MPF Systems Limited a Smart Pick for Retirement PortfoliosStock Correlation Metrics & Build Wealth With Expert Timing Advice - earlytimes.in

Oct 04, 2025
pulisher
Oct 03, 2025

Deutsche Bank sets $31 target for Denali Therapeutics stock - MSN

Oct 03, 2025
pulisher
Oct 03, 2025

BofA Securities Maintains Denali Therapeutics(DNLI.US) With Buy Rating, Maintains Target Price $27 - 富途牛牛

Oct 03, 2025
pulisher
Oct 03, 2025

Why Denali Therapeutics Inc. stock attracts global investorsPortfolio Risk Report & Free Expert Verified Stock Movement Alerts - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Published on: 2025-10-03 02:14:22 - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Published on: 2025-10-03 01:11:36 - newser.com

Oct 03, 2025
pulisher
Oct 02, 2025

Here's Why We're Not Too Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Situation - 富途牛牛

Oct 02, 2025
pulisher
Oct 01, 2025

Denali Therapeutics (NASDAQ:DNLI) Trading 7.4% HigherHere's What Happened - MarketBeat

Oct 01, 2025
pulisher
Oct 01, 2025

What drives Denali Therapeutics Inc 4DN stock priceSector Rotation Strategies & Low Risk Trading Growth - earlytimes.in

Oct 01, 2025
pulisher
Sep 30, 2025

Published on: 2025-09-30 04:04:18 - newser.com

Sep 30, 2025
pulisher
Sep 29, 2025

Denali Therapeutics (DNLI): Evaluating Valuation Disconnect Despite Lack of Major News - Yahoo Finance

Sep 29, 2025
pulisher
Sep 29, 2025

Published on: 2025-09-29 05:10:38 - newser.com

Sep 29, 2025
pulisher
Sep 28, 2025

What drives Denali Therapeutics Inc stock priceSwing Trading Ideas & Low Risk Wealth Plans - earlytimes.in

Sep 28, 2025
pulisher
Sep 28, 2025

What analysts say about Denali Therapeutics Inc stockGlobal Market Influence & Small Investment Capital Tips - earlytimes.in

Sep 28, 2025
pulisher
Sep 28, 2025

Denali Therapeutics Inc Stock Analysis and ForecastSector Leadership Analysis & Free Get High Potential Alerts - earlytimes.in

Sep 28, 2025

Denali Therapeutics Inc Stock (DNLI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Denali Therapeutics Inc Stock (DNLI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Ho Carole
Chief Medical Officer
Aug 12 '25
Sale
13.58
2,937
39,884
217,391
Ho Carole
Chief Medical Officer
Aug 13 '25
Sale
14.64
806
11,800
216,585
$84.73
price up icon 1.11%
$22.93
price up icon 7.40%
$32.68
price up icon 2.73%
$102.30
price up icon 0.24%
$163.94
price up icon 0.99%
biotechnology ONC
$327.03
price up icon 2.16%
Cap:     |  Volume (24h):