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Denali Therapeutics Inc stock is traded at $15.49, with a volume of 2.74M. It is up +1.71% in the last 24 hours and up +11.68% over the past month. Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
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Previous Close:
$15.23
Open:
$15.37
24h Volume:
2.74M
Relative Volume:
1.77
Market Cap:
$2.26B
Revenue:
$340.81M
Net Income/Loss:
$-419.65M
P/E Ratio:
-5.4351
EPS:
-2.85
Net Cash Flow:
$-402.10M
1W Performance:
+5.37%
1M Performance:
+11.68%
6M Performance:
-25.28%
1Y Performance:
-35.16%
1-Day Range:
Value
$15.31
$16.19
1-Week Range:
Value
$14.15
$16.19
52-Week Range:
Value
$10.57
$33.33

Denali Therapeutics Inc Stock (DNLI) Company Profile

Name
Name
Denali Therapeutics Inc
Name
Phone
(650) 866-8547
Name
Address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO
Name
Employee
486
Name
Twitter
Name
Next Earnings Date
2025-08-08
Name
Latest SEC Filings
Name
DNLI's Discussions on Twitter

Compare DNLI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
DNLI
Denali Therapeutics Inc
15.49 2.17B 340.81M -419.65M -402.10M -2.85
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
395.12 99.96B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
589.48 60.83B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
454.38 59.89B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
ARGX
Argen X Se Adr
660.00 40.47B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
313.67 37.96B 3.81B -644.79M -669.77M -6.24

Denali Therapeutics Inc Stock (DNLI) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Mar-07-25 Resumed Morgan Stanley Overweight
Feb-11-25 Initiated Deutsche Bank Buy
Jan-07-25 Initiated Robert W. Baird Outperform
Jan-03-25 Initiated William Blair Outperform
Dec-16-24 Upgrade Stifel Hold → Buy
Oct-10-24 Resumed Raymond James Mkt Perform
Oct-07-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-13-23 Initiated Citigroup Buy
Nov-20-23 Resumed JP Morgan Overweight
Oct-24-23 Resumed Cantor Fitzgerald Overweight
Sep-06-23 Initiated B. Riley Securities Buy
Jan-30-23 Initiated SVB Securities Outperform
Dec-05-22 Initiated Cowen Outperform
Nov-02-22 Upgrade BTIG Research Neutral → Buy
Nov-02-22 Initiated BofA Securities Buy
Jun-23-22 Initiated Berenberg Buy
Dec-10-21 Resumed Raymond James Mkt Perform
Sep-21-21 Initiated Oppenheimer Outperform
Sep-01-21 Initiated SMBC Nikko Outperform
May-18-21 Initiated UBS Buy
Feb-26-21 Reiterated H.C. Wainwright Buy
Feb-10-21 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-11-20 Reiterated H.C. Wainwright Buy
Oct-16-20 Downgrade BTIG Research Buy → Neutral
Sep-14-20 Resumed JP Morgan Overweight
Aug-20-20 Reiterated H.C. Wainwright Buy
Mar-13-20 Upgrade Evercore ISI In-line → Outperform
Feb-28-20 Upgrade Wedbush Neutral → Outperform
Feb-24-20 Initiated Jefferies Buy
Feb-19-20 Initiated Stifel Hold
Jan-27-20 Upgrade Goldman Neutral → Buy
Sep-26-19 Initiated Wedbush Neutral
Sep-13-19 Initiated Nomura Buy
Aug-09-19 Initiated BTIG Research Buy
Jun-26-19 Initiated H.C. Wainwright Buy
Nov-15-18 Initiated Cantor Fitzgerald Overweight
Nov-12-18 Initiated Janney Buy
Mar-12-18 Downgrade Evercore ISI Outperform → In-line
Jan-02-18 Initiated Evercore ISI Outperform
Jan-02-18 Initiated Goldman Neutral
Jan-02-18 Initiated JP Morgan Overweight
Jan-02-18 Initiated Morgan Stanley Overweight
View All

Denali Therapeutics Inc Stock (DNLI) Latest News

pulisher
Aug 20, 2025

Denali Therapeutics Inc. (DNLI) Secures FDA Priority Review for First-Ever Brain-Penetrant Hunter Syndrome Therapy - MSN

Aug 20, 2025
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Aug 20, 2025

Can Denali Therapeutics Inc. Regain Lost Ground This Quarter2025 Price Targets & Smart Swing Trading Alerts - newsyoung.net

Aug 20, 2025
pulisher
Aug 16, 2025

Can Denali Therapeutics Inc. be the next market leaderEarnings Risk Report & Safe Capital Growth Tips - thegnnews.com

Aug 16, 2025
pulisher
Aug 16, 2025

Is Denali Therapeutics Inc. stock technically oversold2025 EndofYear Setup & Low Drawdown Trading Techniques - sundaytimes.kr

Aug 16, 2025
pulisher
Aug 16, 2025

BTIG Reiterates a Buy Rating on Denali Therapeutics (DNLI) With a $32 Price Target - MSN

Aug 16, 2025
pulisher
Aug 15, 2025

Why Denali Therapeutics Shares Are Slipping - TipRanks

Aug 15, 2025
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Aug 15, 2025

Is Denali Therapeutics Inc. subject to activist investor interestTrade Volume Report & AI Optimized Trade Strategies - thegnnews.com

Aug 15, 2025
pulisher
Aug 14, 2025

Denali Therapeutics Inc. Stock Approaches Key Moving Average2025 Valuation Update & Community Verified Swing Trade Signals - sundaytimes.kr

Aug 14, 2025
pulisher
Aug 14, 2025

Denali Therapeutics COFO Schuth sells $39884 in stock By Investing.com - Investing.com Canada

Aug 14, 2025
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Aug 14, 2025

DNLI Tops on Q2 Earnings, Expects Decree on Hunter Syndrome Drug in '26 - MSN

Aug 14, 2025
pulisher
Aug 14, 2025

Denali therapeutics’ Ho Carole sells $52k in stock - Investing.com

Aug 14, 2025
pulisher
Aug 14, 2025

Denali Therapeutics COFO Schuth sells $39884 in stock - Investing.com

Aug 14, 2025
pulisher
Aug 14, 2025

Science Spotlight: How Denali’s CNS-penetrant amyloid mAb may avoid ARIA - BioCentury

Aug 14, 2025
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Aug 14, 2025

XTX Topco Ltd Lowers Stock Holdings in Denali Therapeutics Inc. (NASDAQ:DNLI) - Defense World

Aug 14, 2025
pulisher
Aug 14, 2025

Elliott Wave Theory Predicts Pullback in Denali Therapeutics Inc.July 2025 Reactions & Community Consensus Picks - beatles.ru

Aug 14, 2025
pulisher
Aug 14, 2025

Is now a turning point for Denali Therapeutics Inc.July 2025 Big Picture & Safe Entry Momentum Stock Tips - Newser

Aug 14, 2025
pulisher
Aug 14, 2025

What makes Denali Therapeutics Inc. stock price move sharplyJuly 2025 Earnings & Smart Investment Allocation Insights - Newser

Aug 14, 2025
pulisher
Aug 14, 2025

Earnings visualization tools for Denali Therapeutics Inc.Weekly Profit Summary & Weekly Momentum Picks - Newser

Aug 14, 2025
pulisher
Aug 13, 2025

Technical signs of recovery in Denali Therapeutics Inc.Dividend Hike & Weekly Consistent Profit Watchlists - Newser

Aug 13, 2025
pulisher
Aug 13, 2025

Denali Soars 11% on Biotech Sector Turmoil: What’s Fueling This Surge? - AInvest

Aug 13, 2025
pulisher
Aug 12, 2025

Using data filters to optimize entry into Denali Therapeutics Inc.Stock Trading Session Highlights and Summary - Newser

Aug 12, 2025
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Aug 12, 2025

Denali Therapeutics Inc. Earnings Report Breakdown: What Investors Should KnowSummary of Consistent Growth Stock Picks - Newser

Aug 12, 2025
pulisher
Aug 12, 2025

Denali Therapeutics shares fall 3.52% intraday after reporting mixed Q2 2025 results and regulatory updates. - AInvest

Aug 12, 2025
pulisher
Aug 12, 2025

H.C. Wainwright Maintains Denali Therapeutics(DNLI.US) With Buy Rating, Maintains Target Price $32 - 富途牛牛

Aug 12, 2025
pulisher
Aug 12, 2025

Denali Therapeutics: Advancements in CNS Delivery and Strategic Market Positioning Drive Buy Rating - TipRanks

Aug 12, 2025
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Aug 12, 2025

Denali Therapeutics: Promising Developments and Regulatory Momentum Drive Buy Rating - TipRanks

Aug 12, 2025
pulisher
Aug 12, 2025

Denali Therapeutics Reports Second Quarter 2025 Financial Results and Business Highlights - The Manila Times

Aug 12, 2025
pulisher
Aug 11, 2025

Denali Therapeutics reports Q2 EPS (72c), consensus (74c) - TipRanks

Aug 11, 2025
pulisher
Aug 11, 2025

Denali Therapeutics: Promising Pipeline and Regulatory Progress Justify Buy Rating - TipRanks

Aug 11, 2025
pulisher
Aug 11, 2025

Denali Therapeutics Inc. SEC 10-Q Report - TradingView

Aug 11, 2025
pulisher
Aug 11, 2025

Denali Therapeutics Q2 2025 Financial Results and Business Highlights: Tividenofusp Alfa BLA Accepted for Priority Review, DNL126 Accelerated Approval Path Aligned, and More. - AInvest

Aug 11, 2025
pulisher
Aug 11, 2025

FDA Fast-Tracks Denali's Breakthrough Hunter Syndrome Drug as Pipeline Expands - Stock Titan

Aug 11, 2025
pulisher
Aug 10, 2025

Possible Bearish Signals With Denali Therapeutics Insiders Disposing Stock - 富途牛牛

Aug 10, 2025
pulisher
Aug 07, 2025

BTIG Maintains Denali Therapeutics(DNLI.US) With Buy Rating, Maintains Target Price $32 - 富途牛牛

Aug 07, 2025
pulisher
Aug 06, 2025

Denali Therapeutics (DNLI) to Release Quarterly Earnings on Thursday - Defense World

Aug 06, 2025
pulisher
Aug 05, 2025

Catalyst Pharmaceutics to Report Q2 Earnings: What's in the Cards? - The Globe and Mail

Aug 05, 2025
pulisher
Aug 04, 2025

Is Denali Therapeutics Inc. a good long term investmentMaster stock selection with insider knowledge - Jammu Links News

Aug 04, 2025
pulisher
Aug 03, 2025

How strong is Denali Therapeutics Inc. company’s balance sheetCapitalize on momentum stocks before they peak - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

What are Denali Therapeutics Inc. company’s key revenue driversInvest smarter with daily market updates - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

What institutional investors are buying Denali Therapeutics Inc. stockFree Technical Analysis Support - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

What is Denali Therapeutics Inc. company’s growth strategyConsistent triple-digit returns - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

Is Denali Therapeutics Inc. stock overvalued or undervaluedAchieve unparalleled market performance - Jammu Links News

Aug 03, 2025
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Aug 03, 2025

Does Denali Therapeutics Inc. stock perform well during market downturnsMaximize gains with expert trading strategies - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

How does Denali Therapeutics Inc. generate profit in a changing economyMarket-leading profit generation - Jammu Links News

Aug 03, 2025
pulisher
Aug 03, 2025

Backtesting results for Denali Therapeutics Inc. trading strategiesForecast Model for Intraday Buy Signals - Newser

Aug 03, 2025
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Aug 03, 2025

How volatile is Denali Therapeutics Inc. stock compared to the marketFree Daily Trading Room Entry - Jammu Links News

Aug 03, 2025
pulisher
Aug 02, 2025

What is the risk reward ratio of investing in Denali Therapeutics Inc. stockSky-high return potential - Jammu Links News

Aug 02, 2025
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Aug 02, 2025

Is Denali Therapeutics Inc. a growth stock or a value stockAccelerated financial growth - Jammu Links News

Aug 02, 2025
pulisher
Aug 02, 2025

What are analysts’ price targets for Denali Therapeutics Inc. in the next 12 monthsInvest smarter with cutting-edge analytics - Jammu Links News

Aug 02, 2025
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Aug 02, 2025

Is it the right time to buy Denali Therapeutics Inc. stockTransform your portfolio with high-yield stocks - Jammu Links News

Aug 02, 2025
pulisher
Aug 02, 2025

DNLI's Hunter Syndrome Drug Gets Breakthrough Therapy Designation - MSN

Aug 02, 2025

Denali Therapeutics Inc Stock (DNLI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Denali Therapeutics Inc Stock (DNLI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Ho Carole
Chief Medical Officer
Aug 12 '25
Sale
13.58
2,937
39,884
217,391
Ho Carole
Chief Medical Officer
Aug 13 '25
Sale
14.64
806
11,800
216,585
$24.65
price up icon 0.94%
$85.04
price down icon 1.72%
$26.20
price up icon 0.73%
$110.88
price up icon 0.10%
$131.88
price down icon 0.54%
biotechnology ONC
$313.67
price down icon 0.10%
Cap:     |  Volume (24h):