8.16
price down icon2.28%   -0.19
after-market After Hours: 8.32 0.16 +1.96%
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Fulcrum Therapeutics Inc stock is traded at $8.16, with a volume of 957.07K. It is down -2.28% in the last 24 hours and down -14.55% over the past month. Fulcrum Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases. Its product candidate, Pociredir, is an oral small molecule designed to induce fetal hemoglobin (HbF) and is in clinical development for sickle cell disease (SCD). The company completed dosing in the Phase 1b PIONEER trial evaluating pociredir in adults with SCD and reported clinical data showing clinically relevant HbF induction and improvements in markers of hemolysis and anemia. The company has also generated a pipeline of clinical-stage and pre-clinical programs targeting the root causes of rare genetic diseases.
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Previous Close:
$8.35
Open:
$8.2
24h Volume:
957.07K
Relative Volume:
0.67
Market Cap:
$543.46M
Revenue:
$2.81M
Net Income/Loss:
$-97.34M
P/E Ratio:
-5.1646
EPS:
-1.58
Net Cash Flow:
$-91.47M
1W Performance:
-6.53%
1M Performance:
-14.55%
6M Performance:
+6.53%
1Y Performance:
+151.08%
1-Day Range:
Value
$7.93
$8.24
1-Week Range:
Value
$7.52
$8.835
52-Week Range:
Value
$2.315
$15.74

Fulcrum Therapeutics Inc Stock (FULC) Company Profile

Name
Name
Fulcrum Therapeutics Inc
Name
Phone
617-651-8851
Name
Address
26 LANDSDOWNE STREET, CAMBRIDGE, MA
Name
Employee
55
Name
Twitter
@fulcrumtx
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
FULC's Discussions on Twitter

Compare FULC vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
FULC
Fulcrum Therapeutics Inc
8.16 556.11M 2.81M -97.34M -91.47M -1.58
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
460.82 121.40B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
764.93 83.25B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
728.11 46.39B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
320.51 43.41B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
292.94 33.09B 5.36B 287.73M 924.18M 2.5229

Fulcrum Therapeutics Inc Stock (FULC) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-12-26 Initiated JP Morgan Overweight
Nov-24-25 Initiated Truist Buy
Jul-29-25 Upgrade H.C. Wainwright Neutral → Buy
May-23-25 Upgrade Leerink Partners Market Perform → Outperform
May-15-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Sep-13-24 Downgrade H.C. Wainwright Buy → Neutral
Sep-12-24 Downgrade BofA Securities Neutral → Underperform
Sep-12-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Sep-12-24 Downgrade Leerink Partners Outperform → Market Perform
Sep-12-24 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-12-24 Downgrade Stifel Buy → Hold
Sep-09-24 Upgrade BofA Securities Underperform → Neutral
May-20-24 Initiated Cantor Fitzgerald Overweight
Mar-13-24 Initiated RBC Capital Mkts Outperform
Sep-25-23 Initiated Goldman Neutral
Aug-23-23 Upgrade H.C. Wainwright Neutral → Buy
Aug-22-23 Upgrade Stifel Hold → Buy
May-04-23 Downgrade Goldman Buy → Neutral
Mar-10-23 Downgrade Credit Suisse Outperform → Neutral
Mar-10-23 Downgrade H.C. Wainwright Buy → Neutral
Mar-09-23 Downgrade Stifel Buy → Hold
Feb-28-23 Downgrade Morgan Stanley Overweight → Equal-Weight
Feb-24-23 Downgrade BofA Securities Neutral → Underperform
Nov-15-22 Initiated Goldman Buy
Mar-08-22 Initiated Oppenheimer Outperform
Mar-03-22 Upgrade BofA Securities Underperform → Neutral
Aug-11-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Apr-26-21 Resumed Credit Suisse Outperform
Mar-22-21 Initiated Credit Suisse Outperform
Mar-02-21 Initiated Stifel Buy
Oct-16-20 Initiated Piper Sandler Overweight
Aug-12-20 Downgrade BofA Securities Neutral → Underperform
Aug-12-20 Reiterated H.C. Wainwright Buy
Aug-12-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Jun-19-20 Downgrade BofA/Merrill Buy → Neutral
Jun-17-20 Initiated BTIG Research Buy
Oct-03-19 Initiated H.C. Wainwright Buy
Aug-12-19 Initiated BofA/Merrill Buy
View All

Fulcrum Therapeutics Inc Stock (FULC) Latest News

pulisher
Mar 04, 2026

Hedge Fund Moves: Is Fulcrum Therapeutics Inc part of any ETFJuly 2025 Reactions & Daily Profit Maximizing Tips - baoquankhu1.vn

Mar 04, 2026
pulisher
Mar 03, 2026

FULC Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

Mar 03, 2026
pulisher
Mar 03, 2026

Fulcrum Therapeutics to Participate in the Leerink Partners Global Healthcare Conference - Bitget

Mar 03, 2026
pulisher
Mar 02, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Stock Price Down 7.5%Here's Why - MarketBeat

Mar 02, 2026
pulisher
Feb 28, 2026

FULC Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Feb 28, 2026
pulisher
Feb 27, 2026

Winners Losers: Can Fulcrum Therapeutics Inc keep up with sector leadersBond Market & Stepwise Swing Trade Plans - baoquankhu1.vn

Feb 27, 2026
pulisher
Feb 26, 2026

Fulcrum: Strong HbF Signal, Narrow TAM, Same 'Hold' Conclusion (NASDAQ:FULC) - Seeking Alpha

Feb 26, 2026
pulisher
Feb 26, 2026

Fulcrum Therapeutics, Inc. (FULC): Analyst Ratings Suggest 111% Upside Potential – Is It Time to Buy? - DirectorsTalk Interviews

Feb 26, 2026
pulisher
Feb 26, 2026

HC Wainwright Has Optimistic Outlook of FULC Q1 Earnings - MarketBeat

Feb 26, 2026
pulisher
Feb 26, 2026

FY2030 Earnings Forecast for FULC Issued By HC Wainwright - Defense World

Feb 26, 2026
pulisher
Feb 25, 2026

Fulcrum Therapeutics move lower ‘overdone,’ says Stifel - Yahoo Finance

Feb 25, 2026
pulisher
Feb 25, 2026

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 25, 2026
pulisher
Feb 25, 2026

H.C. Wainwright Maintains Buy on FULC Fulcrum Therapeutics, Inc. Feb 24, 2026 - Meyka

Feb 25, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics, Inc. Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock falls as sickle cell trial misses target - Investing.com Australia

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock falls as sickle cell trial misses target By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Leerink reiterates Fulcrum Therapeutics stock rating on SCD data By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics shares fall on profit-taking, Oppenheimer says By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

BofA reiterates Fulcrum Therapeutics stock Underperform rating at $7 By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Shares Gap DownWhat's Next? - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Shares Surge on Promising Clinical Trial Data and Strong Financial Runway - NewsCase

Feb 24, 2026
pulisher
Feb 24, 2026

Positive Developments in Fulcrum Therapeutics (FULC) Boost Inves - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Q4 Earnings Call Highlights - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (FULC) Shares Experience Unexpected Decline - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (FULC) Surpasses Expectations with Phase Ib Study Results - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

FULC: Pociredir at 20 mg achieved strong HbF induction and clinical benefit in severe sickle cell disease - TradingView

Feb 24, 2026
pulisher
Feb 24, 2026

What's Going On With Fulcrum Therapeutics Stock Tuesday? - Benzinga

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Says Phase 1b Pociredir Trial Demonstrates Improvement in Sickle Cell Disease Therapy - marketscreener.com

Feb 24, 2026
pulisher
Feb 24, 2026

Earnings call transcript: Fulcrum Therapeutics Q4 2025 reports progress in sickle cell treatment - Investing.com

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Releases Quarterly Earnings Results, Meets Expectations - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (FULC) Reports Promising PIONEER Trial Resu - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock tumbles despite trial results By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Biopharmaceutical company Fulcrum Therapeutics recently disclosed that by the end of 2025, its total holdings of cash, cash equivalents, and marketable securities will reach $352.3 million. - Bitget

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock tumbles despite trial results - Investing.com Australia

Feb 24, 2026
pulisher
Feb 24, 2026

FULCRUM THERAPEUTICS ($FULC) Releases Q4 2025 Earnings - Quiver Quantitative

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics, Inc. SEC 10-K Report - TradingView

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics announces positive results from 20 mg dose cohort of phase 1b pioneer trial of Pociredir - marketscreener.com

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (NASDAQ: FULC) posts wider 2025 loss and boosts cash runway - Stock Titan

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Announces Recent Business Highlights - GlobeNewswire

Feb 24, 2026
pulisher
Feb 24, 2026

Experimental sickle cell pill left most patients crisis-free for 12 weeks - Stock Titan

Feb 24, 2026
pulisher
Feb 23, 2026

Fulcrum Therapeutics Announces Recent Business Highlights and Financial Results for Fourth Quarter and Full Year 2025 - Bitget

Feb 23, 2026
pulisher
Feb 23, 2026

Fulcrum Therapeutics Announces Positive 12-Week Results from the 20 mg Dose Cohort of the Phase 1b PIONEER Trial of Pociredir in Sickle Cell Disease - Bitget

Feb 23, 2026
pulisher
Feb 22, 2026

Aberdeen Group plc Acquires 79,265 Shares of Fulcrum Therapeutics, Inc. $FULC - Defense World

Feb 22, 2026
pulisher
Feb 20, 2026

Will Fulcrum Therapeutics Inc. stock benefit from infrastructure spending2025 Pullback Review & Low Drawdown Momentum Trade Ideas - mfd.ru

Feb 20, 2026
pulisher
Feb 20, 2026

Fulcrum Therapeutics Inc expected to post a loss of 31 cents a shareEarnings Preview - TradingView

Feb 20, 2026
pulisher
Feb 20, 2026

Why Fulcrum Therapeutics Inc. stock attracts high net worth investorsEarnings Recap Report & Reliable Volume Spike Alerts - mfd.ru

Feb 20, 2026
pulisher
Feb 19, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Trading 6.5% HigherWhat's Next? - MarketBeat

Feb 19, 2026
pulisher
Feb 19, 2026

Fulcrum Therapeutics, Inc. (FULC) Stock Analysis: Unpacking The 74.59% Potential Upside - DirectorsTalk Interviews

Feb 19, 2026
pulisher
Feb 17, 2026

Fulcrum Therapeutics to Present 12-Week Data from the 20 mg Dose Cohort of the Phase 1b PIONEER Trial of Pociredir in Sickle Cell Disease - The Manila Times

Feb 17, 2026
pulisher
Feb 17, 2026

Fulcrum Therapeutics (FULC) to Release Quarterly Earnings on Tuesday - MarketBeat

Feb 17, 2026
pulisher
Feb 15, 2026

Is Fulcrum Therapeutics Inc. stock a contrarian buyPortfolio Risk Report & Fast Gain Stock Tips - mfd.ru

Feb 15, 2026

Fulcrum Therapeutics Inc Stock (FULC) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$45.68
price down icon 3.69%
$53.83
price down icon 6.87%
$29.72
price up icon 0.68%
$101.95
price down icon 1.78%
$143.57
price down icon 4.21%
biotechnology ONC
$292.94
price down icon 2.03%
Cap:     |  Volume (24h):