99.21
price down icon0.31%   -0.31
after-market After Hours: 103.80 4.59 +4.63%
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Protagonist Therapeutics Inc stock is traded at $99.21, with a volume of 391.03K. It is down -0.31% in the last 24 hours and down -4.40% over the past month. Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
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Previous Close:
$99.52
Open:
$100.32
24h Volume:
391.03K
Relative Volume:
0.52
Market Cap:
$6.38B
Revenue:
$46.02M
Net Income/Loss:
$-130.15M
P/E Ratio:
-48.57
EPS:
-2.0427
Net Cash Flow:
$56.08M
1W Performance:
-1.98%
1M Performance:
-4.40%
6M Performance:
+27.39%
1Y Performance:
+124.05%
1-Day Range:
Value
$97.45
$101.37
1-Week Range:
Value
$97.08
$101.37
52-Week Range:
Value
$41.28
$107.84

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
132
Name
Twitter
Name
Next Earnings Date
2026-05-05
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PTGX icon
PTGX
Protagonist Therapeutics Inc
99.21 6.40B 46.02M -130.15M 56.08M -2.0427
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
424.36 109.34B 12.32B 4.34B 3.19B 16.86
REGN icon
REGN
Regeneron Pharmaceuticals Inc
702.27 74.35B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
794.70 50.44B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
301.11 39.78B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
297.49 33.02B 5.36B 287.73M 924.18M 2.5229

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

pulisher
07:26 AM

Protagonist Therapeutics (NASDAQ:PTGX) Posts Earnings Results, Beats Expectations By $0.70 EPS - MarketBeat

07:26 AM
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04:27 AM

Milestones and Takeda opt-out reshape Protagonist (NASDAQ: PTGX) outlook - Stock Titan

04:27 AM
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04:14 AM

Protagonist Reports First Quarter 2026 Financial Results and Provides Corporate Update - ACCESS Newswire

04:14 AM
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04:08 AM

Protagonist (NASDAQ: PTGX) posts Q1 profit amid ICOTYDE approval and $200M rusfertide opt-out - Stock Titan

04:08 AM
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02:06 AM

Protagonist Therapeutics set to report as blockbuster bets grow - Investing.com

02:06 AM
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02:39 AM

Protagonist Therapeutics, Inc. (NASDAQ:PTGX) Receives Average Rating of "Moderate Buy" from Analysts - MarketBeat

02:39 AM
pulisher
May 04, 2026

(PTGX) Movement Within Algorithmic Entry Frameworks - Stock Traders Daily

May 04, 2026
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May 03, 2026

MSN Money - MSN

May 03, 2026
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May 02, 2026

Protagonist Therapeutics Inc. (PTGX): Billionaire Tom Steyer Likes Upside Potential of This Stock - Insider Monkey

May 02, 2026
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May 02, 2026

331,164 Shares in Protagonist Therapeutics, Inc. $PTGX Bought by Jennison Associates LLC - MarketBeat

May 02, 2026
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May 01, 2026

M&T Bank Corp Acquires New Holdings in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

May 01, 2026
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May 01, 2026

PTGX SEC FilingsProtagonist Ther 10-K, 10-Q, 8-K Forms - Stock Titan

May 01, 2026
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Apr 30, 2026

Vanguard shows 5.09% stake in Protagonist Therapeutics (NASDAQ: PTGX) - Stock Titan

Apr 30, 2026
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Apr 30, 2026

Pictet Asset Management Holding SA Has $46.26 Million Stock Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Apr 30, 2026
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Apr 29, 2026

Vanguard reports 3.53M-share stake in Protagonist Therapeutics (NASDAQ: PTGX) - Stock Titan

Apr 29, 2026
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Apr 29, 2026

Truist Financial Maintains Protagonist Therapeutics(PTGX.US) With Buy Rating - Moomoo

Apr 29, 2026
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Apr 29, 2026

Blood cancer drug translates into $200 million payday for Bay Area company — and there's more to come - The Business Journals

Apr 29, 2026
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Apr 29, 2026

Protagonist Therapeutics, Inc. $PTGX Shares Sold by Moody Aldrich Partners LLC - MarketBeat

Apr 29, 2026
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Apr 29, 2026

UBS Group AG Acquires 874,013 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Protagonist Therapeutics (PTGX) Projected to Post Quarterly Earnings on Wednesday - MarketBeat

Apr 29, 2026
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Apr 28, 2026

[ARS] Protagonist Therapeutics, Inc SEC Filing - Stock Titan

Apr 28, 2026
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Apr 28, 2026

Protagonist Therapeutics (NASDAQ: PTGX) plans 2026 meeting and expanded equity plan - Stock Titan

Apr 28, 2026
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Apr 28, 2026

Protagonist Therapeutics (PTGX) soars 4.7%: Is further upside left in the stock? - MSN

Apr 28, 2026
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Apr 28, 2026

Takeda (TAK) and Protagonist Therapeutics Deal Revisited - GuruFocus

Apr 28, 2026
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Apr 28, 2026

Protagonist Therapeutics Opts Out of Rusfertide US Profit-Sharing Arrangement With Takeda Pharmaceutical - marketscreener.com

Apr 28, 2026
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Apr 28, 2026

Protagonist Exercises Rusfertide U.S. Opt-Out Right Under Takeda Collaboration - Voice of Alexandria

Apr 28, 2026
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Apr 28, 2026

Takeda takes U.S. rights to rusfertide; Protagonist eligible for $475M - Stock Titan

Apr 28, 2026
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Apr 28, 2026

PTGX Stock Price, Quote & Chart | PROTAGONIST THERAPEUTICS INC (NASDAQ:PTGX) - ChartMill

Apr 28, 2026
pulisher
Apr 27, 2026

Protagonist Therapeutics Shifts Focus to High Margin Commercial Royalties - HarianBasis.co

Apr 27, 2026
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Apr 27, 2026

Protagonist Therapeutics Inc. (PTGX): Billionaire Joe Edelman Likes This Stock - Yahoo Finance

Apr 27, 2026
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Apr 27, 2026

Protagonist Therapeutics, Inc. $PTGX Shares Purchased by Universal Beteiligungs und Servicegesellschaft mbH - MarketBeat

Apr 27, 2026
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Apr 24, 2026

CEO of Protagonist (NASDAQ: PTGX) makes bona fide share gift - Stock Titan

Apr 24, 2026
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Apr 24, 2026

PTGX News | PROTAGONIST THERAPEUTICS INC (NASDAQ:PTGX) - ChartMill

Apr 24, 2026
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Apr 23, 2026

PTGX (Protagonist Therapeutics Inc.) rises 2.17 percent even as Q4 2025 EPS falls far below analyst consensus estimates.Profit Guidance - UBND thành phố Hải Phòng

Apr 23, 2026
pulisher
Apr 23, 2026

How (PTGX) Movements Inform Risk Allocation Models - Stock Traders Daily

Apr 23, 2026
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Apr 22, 2026

Polycythemia Vera Market Set for Transformation: Key 9 Companies Expected to Enter by 2036 | DelveInsight - GlobeNewswire Inc.

Apr 22, 2026
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Apr 21, 2026

Insider Selling: Protagonist Therapeutics (NASDAQ:PTGX) CFO Sells 1,750 Shares of Stock - MarketBeat

Apr 21, 2026
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Apr 21, 2026

Protagonist Therapeutics CFO Ali Asif sells $184,572 in shares - Investing.com

Apr 21, 2026
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Apr 21, 2026

Protagonist Therapeutics CFO Ali Asif sells $184,572 in shares By Investing.com - Investing.com Australia

Apr 21, 2026
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Apr 21, 2026

Protagonist Therapeutics (NASDAQ: PTGX) CFO sells shares to cover RSU taxes - Stock Titan

Apr 21, 2026
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Apr 21, 2026

PTGX (NASDAQ) Form 144: 1,750-share sale noted; insider disposals listed - Stock Titan

Apr 21, 2026
pulisher
Apr 21, 2026

Protagonist Therapeutics stock rallies nearly 7% in a week: Here's why - MSN

Apr 21, 2026
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Apr 18, 2026

Protagonist Therapeutics (PTGX) price target increased by 11.65% to 114.50 - MSN

Apr 18, 2026
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Apr 16, 2026

Protagonist Therapeutics Reports Granting of Inducement Awards - ACCESS Newswire

Apr 16, 2026
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Apr 16, 2026

Two new hires get rights to 69,850 Protagonist shares in awards - Stock Titan

Apr 16, 2026
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Apr 15, 2026

PTGX Maintained by Truist Securities -- Price Target Raised to $121 - GuruFocus

Apr 15, 2026
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Apr 15, 2026

Polycythemia Vera Market: Rapid Increment Driven by Innovation by 2034 – DelveInsight | Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Silence Therapeutics, Ionis Pharma, Perseus Proteomics - Barchart.com

Apr 15, 2026
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Apr 15, 2026

Polycythemia Vera Market: Rapid Increment Driven by Innovation - openPR.com

Apr 15, 2026
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Apr 15, 2026

Truist Financial Maintains Protagonist Therapeutics(PTGX.US) With Buy Rating, Maintains Target Price $121 - Moomoo

Apr 15, 2026
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Apr 15, 2026

Wedbush Maintains Protagonist Therapeutics(PTGX.US) With Buy Rating, Maintains Target Price $112 - Moomoo

Apr 15, 2026
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Apr 15, 2026

Protagonist Therapeutics (PTGX) Stock Price Target Hike (Investor Interest) 2026-04-15Momentum Signals - UBND thành phố Hải Phòng

Apr 15, 2026

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$28.32
price down icon 0.14%
$50.44
price up icon 0.48%
$95.50
price down icon 3.88%
$139.44
price down icon 0.41%
$147.21
price down icon 0.47%
ONC ONC
$297.49
price up icon 0.12%
Cap:     |  Volume (24h):