137.34
price down icon0.98%   -1.36
pre-market  Pre-market:  138.70   1.36   +0.99%
loading
Protagonist Therapeutics Inc stock is traded at $137.34, with a volume of 969.84K. It is down -0.98% in the last 24 hours and down -11.23% over the past month. Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
See More
Previous Close:
$138.70
Open:
$138.76
24h Volume:
969.84K
Relative Volume:
1.49
Market Cap:
$8.89B
Revenue:
$74.06M
Net Income/Loss:
$-114.71M
P/E Ratio:
-76.14
EPS:
-1.8039
Net Cash Flow:
$-117.90M
1W Performance:
-4.43%
1M Performance:
-11.23%
6M Performance:
+36.81%
1Y Performance:
+108.25%
1-Day Range:
Value
$134.10
$140.80
1-Week Range:
Value
$134.10
$147.71
52-Week Range:
Value
$62.24
$160.81

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
131
Name
Twitter
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX vs VRTX, REGN, MRNA, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PTGX icon
PTGX
Protagonist Therapeutics Inc
137.34 8.89B 74.06M -114.71M -117.90M -1.8039
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
522.38 132.40B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
796.02 81.95B 14.92B 4.42B 3.79B 41.04
MRNA icon
MRNA
Moderna Inc
194.82 77.78B 2.23B -3.19B -1.60B -8.1462
ARGX icon
ARGX
Argen X Se Adr
962.22 60.20B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
199.86 42.84B 742.00K -1.37B -1.07B -7.0731

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-10-26 Upgrade Goldman Neutral → Buy
May-21-26 Initiated Wolfe Research Outperform
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

pulisher
Sep 24, 2026

Protagonist Therapeutics, Inc. (PTGX) Stock forecasts - Yahoo Finance Singapore

Sep 24, 2026
pulisher
Sep 23, 2026

Protagonist Therapeutics, Inc. (PTGX) stock price, news, quote and history - uk.finance.yahoo.com

Sep 23, 2026
pulisher
Sep 23, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Combines Strong Growth With a High-Quality Technical Setup - ChartMill

Sep 23, 2026
pulisher
Sep 23, 2026

How Protagonist Therapeutics Inc. (PTGX) Affects Rotational Strategy Timing - Stock Traders Daily

Sep 23, 2026
pulisher
Sep 22, 2026

Protagonist Therapeutics, Inc. (PTGX) Stock Price, News, Quote & History - Yahoo! Finance Canada

Sep 22, 2026
pulisher
Sep 22, 2026

Protagonist Therapeutics, Inc. (PTGX) Stock Analysis: Exploring a 20% Potential Upside with Robust Revenue Growth - DirectorsTalk Interviews

Sep 22, 2026
pulisher
Sep 21, 2026

Takeda wins FDA approval for MIMRYLO, triggers $275m payout to Protagonist - scanx.trade

Sep 21, 2026
pulisher
Sep 19, 2026

Protagonist Therapeutics stock holds near 52-week high as investors digest recent earnings - AD HOC NEWS

Sep 19, 2026
pulisher
Sep 18, 2026

Protagonist Therapeutics stock gains as Bank of America builds a sizable stake - AD HOC NEWS

Sep 18, 2026
pulisher
Sep 18, 2026

1,324,498 Shares in Protagonist Therapeutics, Inc. $PTGX Purchased by Bank of America Corp DE - MarketBeat

Sep 18, 2026
pulisher
Sep 15, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Combines High Growth Momentum With a Breakout Setup - ChartMill

Sep 15, 2026
pulisher
Sep 15, 2026

California State Teachers Retirement System Acquires 284 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Sep 15, 2026
pulisher
Sep 13, 2026

VIRGINIA RETIREMENT SYSTEMS ET Al Buys Shares of 11,200 Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Sep 13, 2026
pulisher
Sep 12, 2026

(PTGX) Movement Within Algorithmic Entry Frameworks - Stock Traders Daily

Sep 12, 2026
pulisher
Sep 11, 2026

Protagonist Therapeutics CEO sells $18.2m in shares By Investing.com - Investing.com Australia

Sep 11, 2026
pulisher
Sep 11, 2026

Hsbc Holdings PLC Purchases 24,045 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Sep 11, 2026
pulisher
Sep 10, 2026

Dinesh Ph Patel Sells 63,548 Shares of Protagonist Therapeutics (NASDAQ:PTGX) Stock - MarketBeat

Sep 10, 2026
pulisher
Sep 10, 2026

Insider Selling: Protagonist Therapeutics (NASDAQ:PTGX) CEO Sells 54,174 Shares - MarketBeat

Sep 10, 2026
pulisher
Sep 10, 2026

Protagonist Therapeutics CEO sells $18.2m in shares - Investing.com India

Sep 10, 2026
pulisher
Sep 10, 2026

Protagonist Therapeutics (PTGX) CEO sells 125K shares in preset plan - Stock Titan

Sep 10, 2026
pulisher
Sep 10, 2026

Protagonist Therapeutics(PTGX.US) Officer Sells US$18.24 Million in Common Stock - Moomoo

Sep 10, 2026
pulisher
Sep 10, 2026

Protagonist Therapeutics at Cantor conference: cash, launches and pipeline By Investing.com - Investing.com Nigeria

Sep 10, 2026
pulisher
Sep 09, 2026

Protagonist Therapeutics, Inc. at Citi Biopharma Back to School Summit Transcript - GuruFocus

Sep 09, 2026
pulisher
Sep 09, 2026

Transcript : Protagonist Therapeutics, Inc. Presents at Citigroup?s Biopharma Back to School Summit 2026, Sep-09-2026 10 - marketscreener.com

Sep 09, 2026
pulisher
Sep 09, 2026

Protagonist Therapeutics CEO highlights strong drug approvals and steady biotech progress in 2026. - Pluang

Sep 09, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics authorizes $300 million buyback plan By Investing.com - Investing.com Nigeria

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics (PTGX) CEO gifts stock to family - Stock Titan

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics authorizes $300 million buyback plan - investing.com

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics Announces $300 Million Share Repurchase Program - ACCESS Newswire

Sep 08, 2026
pulisher
Sep 08, 2026

News by ACCESS Newswire on TradingView, 2026-09-08 - TradingView

Sep 08, 2026
pulisher
Sep 08, 2026

Up to $300 million could go toward buying back shares at Protagonist Therapeutics. - Stock Titan

Sep 08, 2026
pulisher
Sep 07, 2026

Ulcerative Colitis Market Outlook: 5 Late-Stage Drug Candidates to Watch | DelveInsight - GlobeNewswire Inc.

Sep 07, 2026
pulisher
Sep 07, 2026

Protagonist Therapeutics, Inc. (NASDAQ:PTGX) Receives Consensus Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Sep 07, 2026
pulisher
Sep 06, 2026

Protagonist (PTGX) Swings To A Profit As Two Drugs Near Blockbuster Status - Yahoo Finance

Sep 06, 2026
pulisher
Sep 04, 2026

MIMRYLO Approval Triggered $275M Payments for Protagonist (PTGX). Are Royalties the Better Commercial Model? - Yahoo Finance

Sep 04, 2026
pulisher
Sep 03, 2026

Protagonist Therapeutics (PTGX) Stock Looks Fully Priced After Its 7x Run - simplywall.st

Sep 03, 2026
pulisher
Sep 02, 2026

Research Analysts Offer Predictions for PTGX Q1 Earnings - marketbeat.com

Sep 02, 2026
pulisher
Sep 02, 2026

Protagonist Therapeutics to Participate in Two Investment Bank Conferences in September 2026 - ACCESS Newswire

Sep 02, 2026
pulisher
Sep 01, 2026

Analysts Are Bullish on Top Healthcare Stocks: Palvella Therapeutics (PVLA), Protagonist Therapeutics (PTGX) - The Globe and Mail

Sep 01, 2026
pulisher
Sep 01, 2026

Protagonist Therapeutics (PTGX) Stock Could Be Overvalued Following FDA Approval News - Yahoo Finance

Sep 01, 2026
pulisher
Sep 01, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Gets A Higher Price Target - Kalkine Media

Sep 01, 2026
pulisher
Sep 01, 2026

BMO raises Protagonist Therapeutics price target on Mimrylo approval By Investing.com - Investing.com Canada

Sep 01, 2026
pulisher
Sep 01, 2026

PTGX Maintained by BMO Capital -- Price Target Raised to $190 - GuruFocus

Sep 01, 2026
pulisher
Sep 01, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Given New $190.00 Price Target at BMO Capital Markets - MarketBeat

Sep 01, 2026
pulisher
Sep 01, 2026

The Bull Case For Protagonist Therapeutics (PTGX) Could Change Following FDA Approval Of MIMRYLO And Takeda Milestones - Yahoo Finance

Sep 01, 2026
pulisher
Sep 01, 2026

Protagonist Therapeutics (PTGX) Could Be 63% Below Fair Value After Investor Update Call - Yahoo Finance

Sep 01, 2026
pulisher
Sep 01, 2026

Why Is Protagonist Therapeutics (PTGX) In Focus After MIMRYLO FDA Approval? - Yahoo Finance

Sep 01, 2026
pulisher
Aug 31, 2026

PTGX Maintained by Citigroup -- Price Target Raised to $182 - GuruFocus

Aug 31, 2026
pulisher
Aug 31, 2026

Protagonist Therapeutics' Mimrylo Holds Commercial Potential After FDA Approval, Truist Says - marketscreener.com

Aug 31, 2026
pulisher
Aug 31, 2026

Citigroup Raises Protagonist Therapeutics Price Target to $182 From $175, Buy Rating Kept - marketscreener.com

Aug 31, 2026
pulisher
Aug 31, 2026

Protagonist Therapeutics stock rating maintained at Buy by Clear Street - Investing.com

Aug 31, 2026

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Protagonist Therapeutics Inc Stock (PTGX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
PATEL DINESH V PH D
President and CEO
Sep 08 '26
Option Exercise
21.58
54,174
1,169,075
577,142
PATEL DINESH V PH D
President and CEO
Sep 10 '26
Option Exercise
21.58
7,278
157,059
530,246
PATEL DINESH V PH D
President and CEO
Sep 09 '26
Sale
146.18
63,548
9,289,447
522,968
PATEL DINESH V PH D
President and CEO
Sep 08 '26
Sale
145.87
54,174
7,902,361
522,968
PATEL DINESH V PH D
President and CEO
Sep 10 '26
Sale
144.10
7,278
1,048,760
522,968
PATEL DINESH V PH D
President and CEO
Aug 10 '26
Option Exercise
21.58
65,761
1,419,122
589,239
PATEL DINESH V PH D
President and CEO
Aug 11 '26
Option Exercise
21.58
34,239
738,878
557,717
PATEL DINESH V PH D
President and CEO
Aug 10 '26
Sale
149.11
65,761
9,805,623
523,478
PATEL DINESH V PH D
President and CEO
Aug 11 '26
Sale
148.52
34,239
5,085,176
523,478
$58.29
price up icon 1.11%
$36.13
price down icon 1.87%
$121.55
price up icon 2.71%
$249.59
price up icon 1.25%
ONC ONC
$359.97
price down icon 1.38%
$199.86
price up icon 4.78%
Cap:     |  Volume (24h):