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Protagonist Therapeutics Inc stock is traded at $95.35, with a volume of 1.29M. It is up +3.36% in the last 24 hours and up +12.37% over the past month. Protagonist Therapeutics Inc is a clinical-stage biopharmaceutical company having a proprietary technology platform that enables the discovery and development of novel constrained peptide-based drug candidates to address medical needs. Its pipeline products include Rusfertide (PTG-300) and JNJ-2113.
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Previous Close:
$92.25
Open:
$92.72
24h Volume:
1.29M
Relative Volume:
1.12
Market Cap:
$5.96B
Revenue:
$209.18M
Net Income/Loss:
$52.04M
P/E Ratio:
133.82
EPS:
0.7125
Net Cash Flow:
$37.10M
1W Performance:
+6.36%
1M Performance:
+12.37%
6M Performance:
+69.30%
1Y Performance:
+136.13%
1-Day Range:
Value
$91.70
$95.39
1-Week Range:
Value
$88.30
$95.39
52-Week Range:
Value
$33.70
$95.39

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
128
Name
Twitter
Name
Next Earnings Date
2025-05-02
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PTGX
Protagonist Therapeutics Inc
95.35 5.77B 209.18M 52.04M 37.10M 0.7125
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.04 113.14B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
741.29 78.49B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
877.94 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
397.55 54.51B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
197.01 41.64B 447.02M -1.18B -906.14M -6.1812

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

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Dec 13, 2025

Protagonist Therapeutics (NASDAQ:PTGX) Hits New 1-Year HighWhat's Next? - MarketBeat

Dec 13, 2025
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Dec 13, 2025

Protagonist Therapeutics, Inc. $PTGX Shares Purchased by BVF Inc. IL - MarketBeat

Dec 13, 2025
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Dec 13, 2025

683 Capital Management LLC Reduces Stake in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 13, 2025
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Dec 12, 2025

Protagonist Therapeutics stock hits all-time high at 93.53 USD By Investing.com - Investing.com Australia

Dec 12, 2025
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Dec 12, 2025

OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC Has $803,000 Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 12, 2025
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Dec 12, 2025

Natixis Purchases Shares of 42,040 Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 12, 2025
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Dec 11, 2025

VIX Spike: How Protagonist Therapeutics Inc stock benefits from strong dollar2025 Winners & Losers & Fast Entry Momentum Trade Alerts - moha.gov.vn

Dec 11, 2025
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Dec 11, 2025

How (PTGX) Movements Inform Risk Allocation Models - news.stocktradersdaily.com

Dec 11, 2025
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Dec 11, 2025

HighVista Strategies LLC Lowers Holdings in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 11, 2025
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Dec 11, 2025

High Growth Tech Stocks In The US Market With Potential - Yahoo Finance

Dec 11, 2025
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Dec 10, 2025

Stempoint Capital LP Trims Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 10, 2025
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Dec 10, 2025

Diadema Partners LP Makes New $4.21 Million Investment in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 10, 2025
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Dec 10, 2025

Protagonist Reports Third Quarter 2025 Financial Results and Provides Corporate Update - Daily Comet

Dec 10, 2025
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Dec 09, 2025

Polycythemia Vera Clinical Trial Pipeline Shows Potential with Active Contributions from 8+ Key Companies | DelveInsight - The Globe and Mail

Dec 09, 2025
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Dec 09, 2025

Protagonist Therapeutics Announces Oral and Poster Presentations on Rusfertide at the 67th Annual ASH Meeting - Press & Sun-Bulletin

Dec 09, 2025
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Dec 08, 2025

Citigroup Maintains Protagonist Therapeutics (PTGX) Buy Recommendation - Nasdaq

Dec 08, 2025
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Dec 08, 2025

PTGX Stock Receives Positive Analyst Rating Update from Citigrou - GuruFocus

Dec 08, 2025
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Dec 08, 2025

Polycythemia Vera Market Positioned for Accelerated Development Through 2034, DelveInsight Finds | Novartis, Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Silence Therapeutics, Ionis Pharm - Barchart.com

Dec 08, 2025
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Dec 08, 2025

Protagonist Announces Icotrokinra Phase 2b ANTHEM-UC Trial Data to be Presented at the United European Gastroenterology Week Berlin 2025 - Livingston Daily

Dec 08, 2025
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Dec 08, 2025

Is Rusfertide’s Phase 3 VERIFY Durability Data Altering The Investment Case For Protagonist Therapeutics (PTGX)? - Sahm

Dec 08, 2025
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Dec 07, 2025

Protagonist Announces Presentations of Clinical Data with Icotrokinra in Plaque Psoriasis and Preclinical Data with PN-881 at the EADV 2025 Congress - Asbury Park Press

Dec 07, 2025
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Dec 06, 2025

Protagonist and Takeda Present Longer-Term Data at ASH 2025 Showing Rusfertide Delivers Durable Response and Hematocrit Control in Polycythemia Vera - STT Info

Dec 06, 2025
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Dec 06, 2025

Protagonist Announces New Icotrokinra Data in Ulcerative Colitis Showing Potential for a Standout Combination of Therapeutic Benefit and a Favorable Safety Profile in Once-daily Pill - Central New Jersey News

Dec 06, 2025
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Dec 06, 2025

Protagonist Therapeutics, Inc. (NASDAQ:PTGX) Receives Consensus Rating of "Moderate Buy" from Analysts - MarketBeat

Dec 06, 2025
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Dec 06, 2025

Affinity Asset Advisors LLC Reduces Stock Holdings in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 06, 2025
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Dec 05, 2025

Protagonist Therapeutics, Inc. (PTGX): A Bull Case Theory - Insider Monkey

Dec 05, 2025
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Dec 05, 2025

Is Protagonist Therapeutics (PTGX) Overvalued After Its Recent Biotech Rally? A Fresh Look at the Valuation - Sahm

Dec 05, 2025
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Dec 05, 2025

What dividend safety score for Protagonist Therapeutics Inc. stock2025 Earnings Surprises & Trade Opportunity Analysis Reports - Newser

Dec 05, 2025
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Dec 04, 2025

How currency fluctuations impact Protagonist Therapeutics Inc. stock2025 Year in Review & Scalable Portfolio Growth Ideas - Newser

Dec 04, 2025
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Dec 03, 2025

How Protagonist Therapeutics Inc. stock compares to growth peers2025 Earnings Surprises & High Accuracy Investment Entry Signals - Newser

Dec 03, 2025
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Dec 03, 2025

Prudential Financial Inc. Has $4.28 Million Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 03, 2025
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Dec 03, 2025

Legal & General Group Plc Grows Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 03, 2025
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Dec 03, 2025

Capital Fund Management S.A. Acquires New Holdings in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 03, 2025
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Dec 02, 2025

Skandinaviska Enskilda Banken AB publ Lowers Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Dec 02, 2025
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Nov 30, 2025

Trading Systems Reacting to (PTGX) Volatility - news.stocktradersdaily.com

Nov 30, 2025
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Nov 30, 2025

Ensign Peak Advisors Inc Decreases Stock Position in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Nov 30, 2025
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Nov 30, 2025

Protagonist Therapeutics, Inc. $PTGX Shares Purchased by American Century Companies Inc. - MarketBeat

Nov 30, 2025
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Nov 30, 2025

Protagonist Therapeutics (PTGX) Price Target Increased by 16.48% to 91.65 - MSN

Nov 30, 2025
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Nov 28, 2025

Protagonist Therapeutics, Inc. $PTGX Shares Bought by Creative Planning - MarketBeat

Nov 28, 2025
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Nov 28, 2025

Protagonist Therapeutics to Host Conference Call to Announce an Oral Obesity Development Candidate - Oak Ridger

Nov 28, 2025
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Nov 27, 2025

Why Protagonist Therapeutics Inc. stock remains undervaluedDividend Hike & Fast Moving Stock Trade Plans - BỘ NỘI VỤ

Nov 27, 2025
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Nov 27, 2025

Protagonist Therapeutics, Inc. (PTGX) Stock Forecasts - Yahoo Finance

Nov 27, 2025
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Nov 27, 2025

Protagenic Therapeutics Announces Receipt of Nasdaq Non-Compliance Notice - Newswire.com

Nov 27, 2025
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Nov 26, 2025

Protagonist Therapeutics, Inc. $PTGX Shares Acquired by Universal Beteiligungs und Servicegesellschaft mbH - MarketBeat

Nov 26, 2025
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Nov 26, 2025

Protagonist Therapeutics Reaches Analyst Target Price - Nasdaq

Nov 26, 2025
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Nov 25, 2025

Jefferies Financial Group Inc. Buys 192,126 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Nov 25, 2025
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Nov 25, 2025

120,159 Shares in Protagonist Therapeutics, Inc. $PTGX Purchased by Segall Bryant & Hamill LLC - MarketBeat

Nov 25, 2025
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Nov 24, 2025

[Form 4] Protagonist Therapeutics, Inc Insider Trading Activity - Stock Titan

Nov 24, 2025
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Nov 24, 2025

Geode Capital Management LLC Buys 20,671 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Nov 24, 2025
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Nov 23, 2025

Intech Investment Management LLC Acquires 2,971 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Nov 23, 2025
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Nov 22, 2025

J.P. Morgan Keeps Their Buy Rating on Protagonist Therapeutics (PTGX) - The Globe and Mail

Nov 22, 2025

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Protagonist Therapeutics Inc Stock (PTGX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Waddill William D.
Director
Oct 10 '25
Option Exercise
6.98
12,000
83,760
17,130
Waddill William D.
Director
Oct 10 '25
Sale
81.62
12,000
979,480
5,130
$38.39
price down icon 1.08%
$95.41
price down icon 0.72%
$31.31
price down icon 3.07%
$94.81
price down icon 1.24%
biotechnology ONC
$319.06
price down icon 0.55%
$197.01
price up icon 0.91%
Cap:     |  Volume (24h):