91.00
price up icon1.61%   1.44
pre-market  Pre-market:  90.03   -0.97   -1.07%
loading
Rhythm Pharmaceuticals Inc stock is traded at $91.00, with a volume of 818.32K. It is up +1.61% in the last 24 hours and down -15.72% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
See More
Previous Close:
$89.56
Open:
$89.56
24h Volume:
818.32K
Relative Volume:
1.05
Market Cap:
$6.07B
Revenue:
$189.76M
Net Income/Loss:
$-196.54M
P/E Ratio:
-29.27
EPS:
-3.1087
Net Cash Flow:
$-156.63M
1W Performance:
-8.22%
1M Performance:
-15.72%
6M Performance:
-12.98%
1Y Performance:
+70.99%
1-Day Range:
Value
$88.03
$91.66
1-Week Range:
Value
$87.19
$103.25
52-Week Range:
Value
$45.91
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
283
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
RYTM
Rhythm Pharmaceuticals Inc
91.00 5.98B 189.76M -196.54M -156.63M -3.1087
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
477.89 120.48B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
787.50 81.05B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
749.56 46.33B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
327.30 42.26B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
299.02 32.87B 5.36B 287.73M 924.18M 2.5229

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Mar 04, 2026

Proposed sale of 64,540 common shares under registered plan (RYTM) - Stock Titan

Mar 04, 2026
pulisher
Mar 04, 2026

HC Wainwright Issues Negative Estimate for RYTM Earnings - MarketBeat

Mar 04, 2026
pulisher
Mar 03, 2026

Rhythm Pharmaceuticals (RYTM) CAO exercises RSUs, withholds shares for taxes - Stock Titan

Mar 03, 2026
pulisher
Mar 03, 2026

Jefferies reiterates Rhythm Pharmaceuticals stock rating on trial outlook By Investing.com - Investing.com Canada

Mar 03, 2026
pulisher
Mar 03, 2026

RYTM (NASDAQ: RYTM) brokered notice for 35,460-share sale on 03/03/2026 - Stock Titan

Mar 03, 2026
pulisher
Mar 03, 2026

Does Rhythm Pharmaceuticals (RYTM) Share Price Reflect Its Obesity Treatment Potential Today - simplywall.st

Mar 03, 2026
pulisher
Mar 03, 2026

Rhythm Pharmaceuticals price target lowered to $110 from $125 at H.C. Wainwright - Yahoo Finance

Mar 03, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals (RYTM) CFO exercises options, acquiring 6,099 shares - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Canaccord Genuity Lowers Price Target for RYTM, Maintains Buy Ra - GuruFocus

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target Lowered to $140.00 at Canaccord Genuity Group - MarketBeat

Mar 02, 2026
pulisher
Mar 02, 2026

HC Wainwright Cuts Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target to $110.00 - MarketBeat

Mar 02, 2026
pulisher
Mar 02, 2026

RYTM: HC Wainwright & Co. Lowers Price Target Despite Maintainin - GuruFocus

Mar 02, 2026
pulisher
Mar 02, 2026

Why Is Rhythm Pharmaceuticals Stock Trading Higher Today?Rhythm Pharmaceuticals (NASDAQ:RYTM) - Benzinga

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Investor Outlook: Robust Analyst Ratings Signal Potential 51.69% Upside - DirectorsTalk Interviews

Mar 02, 2026
pulisher
Mar 02, 2026

Canaccord lowers Rhythm Pharmaceuticals stock price target to $140 - Investing.com

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Says New Late-Stage Data for Obesity Drug Shows Strong Weight Loss, Hunger Reduction - marketscreener.com

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Highlights Positive Phase 3 Data in Hypothalamic Obesity - TipRanks

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals posts 18.8% placebo‑adjusted BMI reduction in TRANSCEND Phase 3 52‑week data - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals (Nasdaq: RYTM) adds positive Phase 3 HO data ahead FDA PDUFA - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Rhythm Pharmaceuticals Nears Key FDA Calls With Global Growth Potential - Sahm

Mar 02, 2026
pulisher
Mar 01, 2026

Rhythm Pharmaceuticals (RYTM) Reveals Promising Phase 3 Trial Da - GuruFocus

Mar 01, 2026
pulisher
Mar 01, 2026

A Look At Rhythm Pharmaceuticals (RYTM) Valuation After Recent Pullback In Share Price - Yahoo Finance

Mar 01, 2026
pulisher
Mar 01, 2026

Rhythm Pharmaceuticals says PDUFA goal date for setmelanotide is March 20, 2026 - marketscreener.com

Mar 01, 2026
pulisher
Mar 01, 2026

Rhythm Pharmaceuticals Says PDUFA Goal Date For Setmelanotide Is March 20, 2026 - TradingView

Mar 01, 2026
pulisher
Mar 01, 2026

Obesity drug shows 18.8% BMI edge, backing first FDA bid in acquired HO - Stock Titan

Mar 01, 2026
pulisher
Mar 01, 2026

Artisan Partners Limited Partnership Buys 62,362 Shares of Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 01, 2026
pulisher
Feb 28, 2026

RYTM SEC FilingsRhythm Pharmaceu 10-K, 10-Q, 8-K Forms - Stock Titan

Feb 28, 2026
pulisher
Feb 27, 2026

Rhythm Pharmaceuticals, Inc. 2025 Q4ResultsEarnings Call Presentation (NASDAQ:RYTM) 2026-02-27 - Seeking Alpha

Feb 27, 2026
pulisher
Feb 27, 2026

Wells Fargo & Company Cuts Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target to $136.00 - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

Rhythm Pharmaceuticals (RYTM) Price Target Lowered by Wells Farg - GuruFocus

Feb 27, 2026
pulisher
Feb 27, 2026

RBC Capital Adjusts Price Target on Rhythm Pharmaceuticals to $140 From $145, Maintains Outperform Rating - marketscreener.com

Feb 27, 2026
pulisher
Feb 27, 2026

Citizens Jmp Raises Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target to $176.00 - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

Is Rhythm Pharmaceuticals Inc. stock risky to hold now2025 Major Catalysts & Free Fast Entry Momentum Trade Alerts - mfd.ru

Feb 27, 2026
pulisher
Feb 27, 2026

Needham & Company LLC Issues Pessimistic Forecast for Rhythm Pharmaceuticals (NASDAQ:RYTM) Stock Price - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

Guggenheim Issues Positive Forecast for Rhythm Pharmaceuticals (NASDAQ:RYTM) Stock Price - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

RYTM Stock Update: Guggenheim Maintains 'Buy', Raises Price Targ - GuruFocus

Feb 27, 2026
pulisher
Feb 27, 2026

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 27, 2026
pulisher
Feb 27, 2026

Guggenheim raises Rhythm Pharmaceuticals stock price target on guidance By Investing.com - Investing.com Canada

Feb 27, 2026
pulisher
Feb 27, 2026

Rhythm Pharmaceuticals Q4 Earnings Call Highlights - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

Citizens raises Rhythm Pharmaceuticals stock price target on HO approval outlook - Investing.com Nigeria

Feb 27, 2026
pulisher
Feb 27, 2026

Rhythm Pharmaceuticals (RYTM) Financials 2026Income Statement and Balance Sheet - MarketBeat

Feb 27, 2026
pulisher
Feb 27, 2026

Decoding Rhythm Pharmaceuticals Inc (RYTM): A Strategic SWOT Ins - GuruFocus

Feb 27, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Issues Quarterly Earnings Results, Beats Expectations By $0.06 EPS - MarketBeat

Feb 26, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals files for mixed shelf - marketscreener.com

Feb 26, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals, Inc. Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 26, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals Inc. (referred to as Rhythm Pharmaceuticals) recently disclosed that some of its shareholders plan to further sell up to 2.4 million shares of common stock. - Bitget

Feb 26, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals Files For Mixed Shelf - TradingView

Feb 26, 2026
pulisher
Feb 26, 2026

Rhythm Pharmaceuticals Inc (RYTM) Q4 2025 Earnings Call Highligh - GuruFocus

Feb 26, 2026
pulisher
Feb 26, 2026

Stifel reiterates Buy on Rhythm Pharmaceuticals stock, $131 target - Investing.com Nigeria

Feb 26, 2026
pulisher
Feb 26, 2026

Stifel reiterates Buy on Rhythm Pharmaceuticals stock, $131 target By Investing.com - Investing.com India

Feb 26, 2026
pulisher
Feb 26, 2026

Earnings call transcript: Rhythm Pharmaceuticals beats Q4 2025 expectations - Investing.com

Feb 26, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$47.43
price down icon 0.11%
$29.52
price up icon 6.00%
$57.80
price up icon 15.99%
$103.80
price up icon 3.02%
$149.88
price up icon 1.96%
biotechnology ONC
$299.02
price up icon 0.67%
Cap:     |  Volume (24h):