6.46

1.22% -0.08

Sionna Therapeutics Inc (SION)

Overview News Price History Discussions Forecast

Sionna Therapeutics Inc stock is traded at $6.46, with a volume of 2.86M. It is down -1.22% in the last 24 hours and down -84.83% over the past month. Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefits to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.

Previous Close:

$6.54

Open:

$6.24

24h Volume:

2.86M

Relative Volume:

1.88

Market Cap:

$292.07M

Revenue:

Net Income/Loss:

$-85.57M

P/E Ratio:

-3.3706

EPS:

-1.9166

Net Cash Flow:

$-72.14M

1W Performance:

-87.34%

1M Performance:

-84.83%

6M Performance:

-82.78%

1Y Performance:

-69.11%

1-Day Range:

$6.15

$6.66

1-Week Range:

$4.01

$6.75

52-Week Range:

$4.01

$54.97

Sionna Therapeutics Inc Stock (SION) Company Profile

Name

Sionna Therapeutics Inc

Sector

Healthcare (1080)

Industry

Biotechnology (604)

Phone

617-819-2020

Address

21 HICKORY DRIVE, SUITE 500, WALTHAM

Employee

Twitter

Next Earnings Date

2026-08-10

Latest SEC Filings

SION's Discussions on Twitter

Compare SION vs VRTX, REGN, ARGX, RVMD, ONC

Stocks	Price	Market Cap	Revenue	Net Income	Cash Flow	EPS
SION Sionna Therapeutics Inc	6.46	282.58M	0	-85.57M	-72.14M	-1.9166
VRTX Vertex Pharmaceuticals Inc	505.75	133.25B	12.34B	4.34B	3.71B	16.87
REGN Regeneron Pharmaceuticals Inc	803.48	82.16B	14.92B	4.42B	3.79B	41.04
ARGX Argen X Se Adr	851.29	54.80B	4.16B	1.29B	734.26M	19.58
RVMD Revolution Medicines Inc	203.71	43.99B	742.00K	-1.37B	-1.07B	-7.0731
ONC Beone Medicines Ltd Adr	347.48	40.62B	5.76B	514.49M	1.10B	4.4813

Sionna Therapeutics Inc Stock (SION) Upgrades & Downgrades

Date	Action	Analyst	Rating Change
Feb-24-26	Initiated	Citizens	Mkt Outperform
Dec-01-25	Downgrade	RBC Capital Mkts	Sector Perform → Underperform
Nov-19-25	Initiated	BTIG Research	Buy
Sep-03-25	Initiated	RBC Capital Mkts	Sector Perform
Sep-03-25	Initiated	Raymond James	Strong Buy
Mar-04-25	Initiated	Guggenheim	Buy
Mar-04-25	Initiated	Stifel	Buy
Mar-04-25	Initiated	TD Cowen	Buy

View All

Sionna Therapeutics Inc Stock (SION) Latest News

02:09 AM

Sionna Therapeutics (NASDAQ:SION) Lowered to Strong Sell Rating by Wall Street Zen - MarketBeat

02:09 AM

Aug 14, 2026

SION Investor Alert: Levi & Korsinsky Notifies Investors of Investigation Into Sionna Therapeutics (SION) - Business Wire

Aug 14, 2026

Aug 13, 2026

SION SHAREHOLDER INVESTIGATION: SueWallSt Notifies Investors of Potential Securities Claims Involving Sionna Therapeutics - PR Newswire

Aug 13, 2026

Sionna Therapeutics (SION) Resets After Trial Miss, Is The Discount Now Too Deep? - Yahoo Finance

Aug 13, 2026

Sionna Therapeutics (SION) Is Down 86.8% After Halting SION-719 And Refocusing Its CF Pipeline – Has The Bull Case Changed? - Yahoo Finance

Aug 13, 2026

Aug 12, 2026

SION ALERT: Investigation Launched into Sionna Therapeutics, Inc., RGRD Law Attorneys Encourage Investors and Potential Witnesses to Contact Law Firm - PR Newswire

Aug 12, 2026

Sionna Therapeutics Investigation Notice: Levi & Korsinsky Notifies Investors of Pending Investigation Into Sionna Therapeutics (SION) - morningstar.com

Aug 12, 2026

12 Health Care Stocks Moving In Wednesday's Intraday Session - benzinga.com

Aug 12, 2026

Sionna's SION-719 Failure Changes Everything (Rating Downgrade) - Seeking Alpha

Aug 12, 2026

Sionna Therapeutics (NASDAQ:SION) Downgraded to Hold Rating by Lifesci Capital - MarketBeat

Aug 12, 2026

Sionna Therapeutics (NASDAQ:SION) Lowered to Hold Rating by JonesTrading - MarketBeat

Aug 12, 2026

Sionna Therapeutics (SION) Stock Still Looks Cheap After The 90% Fall - Yahoo Finance

Aug 12, 2026

Aug 11, 2026

One Company’s Clinical Miss Is Another’s Moat: Vertex Rallies as Sionna’s CF Bet Collapses - Yahoo Finance

Aug 11, 2026

SION Stock On Track For Worst Day Ever After 90% Drop — What’s Driving The Selloff? - Stocktwits

Aug 11, 2026

SION Stock Slides, Then Snaps Back As Traders Eye Volatility - StocksToTrade

Aug 11, 2026