0.7542
price up icon1.92%   0.0142
after-market After Hours: .75 -0.0042 -0.56%
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Spero Therapeutics Inc stock is traded at $0.7542, with a volume of 35,941. It is up +1.92% in the last 24 hours and down -2.17% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$0.74
Open:
$0.74
24h Volume:
35,941
Relative Volume:
0.19
Market Cap:
$39.19M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
75.42
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
+30.60%
1M Performance:
-2.17%
6M Performance:
-41.31%
1Y Performance:
-49.72%
1-Day Range:
Value
$0.74
$0.786
1-Week Range:
Value
$0.522
$0.829
52-Week Range:
Value
$0.5052
$1.72

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

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SPRO
Spero Therapeutics Inc
0.7542 39.19M 76.19M -1.61M 28.98M 0.01
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Vertex Pharmaceuticals Inc
489.10 127.47B 11.02B -535.60M -978.00M -2.20
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563.16 62.43B 14.20B 4.41B 3.54B 38.28
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ARGX
Argen X Se Adr
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ALNY
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234.56 31.06B 2.25B -278.16M -42.59M -2.17
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ONC
Beigene Ltd Adr
230.98 26.16B 3.81B -644.79M -669.77M -6.24

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
Apr 12, 2025

Prudential Financial Inc. Acquires Shares of 49,200 Spero Therapeutics, Inc. (NASDAQ:SPRO) - Defense World

Apr 12, 2025
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Apr 09, 2025

Spero Therapeutics stock hits 52-week low at $0.51 amid challenges - Investing.com Canada

Apr 09, 2025
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Apr 09, 2025

Spero Therapeutics stock hits 52-week low at $0.51 amid challenges By Investing.com - Investing.com South Africa

Apr 09, 2025
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Apr 05, 2025

Spero Therapeutics, Inc. CLASS ACTION Alert: Wolf Haldenstein Adler Freeman & Herz LLP announces that a securities class action lawsuit has been filed in the United States District Court for the Eastern District of New York against Spero Therapeutics, Inc. - MarketScreener

Apr 05, 2025
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Apr 02, 2025

Virtu Financial LLC Makes New $47,000 Investment in Spero Therapeutics, Inc. (NASDAQ:SPRO) - Defense World

Apr 02, 2025
pulisher
Mar 29, 2025

We're Keeping An Eye On Spero Therapeutics' (NASDAQ:SPRO) Cash Burn Rate - Yahoo Finance

Mar 29, 2025
pulisher
Mar 28, 2025

Earnings call transcript: Spero Therapeutics Q4 2024 misses EPS forecast - Investing.com India

Mar 28, 2025
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Mar 28, 2025

Spero Therapeutics Inc (SPRO) Q4 2024 Earnings Call Highlights: Navigating Financial Challenges ... - Yahoo Finance

Mar 28, 2025
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Mar 28, 2025

Spero Therapeutics Inc (SPRO) Q4 2024 Earnings Call Highlights: - GuruFocus

Mar 28, 2025
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Mar 27, 2025

Earnings call transcript: Spero Therapeutics Q4 2024 misses EPS forecast By Investing.com - Investing.com South Africa

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics earnings missed by $0.02, revenue topped estimates - Investing.com Canada

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update - GlobeNewswire

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics, Inc. (SPRO) Reports Q4 Loss, Tops Revenue Estimates - Yahoo Finance

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics Inc reports results for the quarter ended December 31Earnings Summary - TradingView

Mar 27, 2025
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Mar 27, 2025

SPERO THERAPEUTICS Earnings Results: $SPRO Reports Quarterly Earnings - Nasdaq

Mar 27, 2025
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Mar 27, 2025

Spero Q4 Earnings: $68.6M Loss, Pipeline Setbacks, and New Interim CEO Named - Stock Titan

Mar 27, 2025
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Mar 26, 2025

A Glimpse of Spero Therapeutics's Earnings Potential - Benzinga

Mar 26, 2025
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Mar 25, 2025

Spero Therapeutics Inc expected to post a loss of 31 cents a shareEarnings Preview - TradingView

Mar 25, 2025
pulisher
Mar 25, 2025

Spero Therapeutics (NASDAQ:SPRO) Stock Passes Below Two Hundred Day Moving Average – Here’s What Happened - Defense World

Mar 25, 2025
pulisher
Mar 25, 2025

Spero Therapeutics (NASDAQ:SPRO) Share Price Passes Below 200-Day Moving Average – Should You Sell? - The AM Reporter

Mar 25, 2025
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Mar 19, 2025

Spero Therapeutics to Report Fourth Quarter and Full Year - GlobeNewswire

Mar 19, 2025
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Mar 18, 2025

Spero Therapeutics Q4 Earnings: Rare Disease Pipeline and Financial Results Coming March 27 - StockTitan

Mar 18, 2025
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Mar 14, 2025

Spero Therapeutics (NASDAQ:SPRO) Shares Pass Below Two Hundred Day Moving Average – Here’s Why - The AM Reporter

Mar 14, 2025
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Mar 11, 2025

Spero Therapeutics stock hits 52-week low at $0.74 amid challenges - Investing.com Australia

Mar 11, 2025
pulisher
Mar 11, 2025

Spero Therapeutics stock hits 52-week low at $0.74 amid challenges By Investing.com - Investing.com South Africa

Mar 11, 2025
pulisher
Mar 10, 2025

Spero Therapeutics (SPRO) Projected to Post Earnings on Wednesday - The AM Reporter

Mar 10, 2025
pulisher
Mar 06, 2025

Spero Therapeutics, Inc. to Host Earnings Call - ACCESS Newswire

Mar 06, 2025
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Mar 05, 2025

Spero Therapeutics (SPRO) Expected to Announce Quarterly Earnings on Wednesday - Defense World

Mar 05, 2025
pulisher
Mar 04, 2025

Non- Tuberculous Mycobacterial Infections Market on Track for Major Expansion by 2034, According to DelveInsight | Insmed, AN2 Therapeutics, Mannkind Corp., Spero Therapeutics, Savara Pharma - Barchart

Mar 04, 2025
pulisher
Mar 03, 2025

Mersana Therapeutics, Inc. (MRSN) Reports Q4 Loss, Tops Revenue Estimates - Yahoo Finance

Mar 03, 2025
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Mar 01, 2025

Evercore ISI Group Downgrades Spero Therapeutics (SPRO) - MSN

Mar 01, 2025
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Mar 01, 2025

Spero Therapeutics faces Nasdaq delisting over share price By Investing.com - Investing.com Australia

Mar 01, 2025
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Mar 01, 2025

Spero Therapeutics faces Nasdaq delisting over share price - Investing.com India

Mar 01, 2025
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Feb 25, 2025

Spero Therapeutics to Present at TD Cowen 45th Annual Health Care Conference - GlobeNewswire

Feb 25, 2025
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Feb 25, 2025

UPDATESpero Therapeutics to Present at TD Cowen 45th Annual Health Care Conference - The Manila Times

Feb 25, 2025
pulisher
Feb 25, 2025

Marjorie Taylor Greene Is Betting Big on Palantir Stock. Should You? - The Globe and Mail

Feb 25, 2025
pulisher
Feb 25, 2025

UPDATE – Spero Therapeutics to Present at TD Cowen 45th Annual Health Care Conference - GlobeNewswire

Feb 25, 2025
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Feb 25, 2025

Rare Disease Biotech Spero Therapeutics Takes Stage at Major TD Cowen Healthcare Conference - StockTitan

Feb 25, 2025
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Feb 25, 2025

Can Spero Therapeutics' Rare Disease Pipeline Impress Investors at Major Healthcare Conference? - StockTitan

Feb 25, 2025
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Feb 07, 2025

Spero Therapeutics COO Timothy Keutzer sells shares for $44,097 - MSN

Feb 07, 2025
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Feb 06, 2025

Spero therapeutics CFO sells $16,137 in stock By Investing.com - Investing.com Nigeria

Feb 06, 2025
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Feb 06, 2025

Spero Therapeutics Inc (SPRO)’s results reveal risk - US Post News

Feb 06, 2025
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Feb 06, 2025

Spero therapeutics director Ankit Mahadevia sells $53,990 in stock By Investing.com - Investing.com Australia

Feb 06, 2025
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Feb 06, 2025

Spero Therapeutics CEO sells shares worth $121,159 - MSN

Feb 06, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Spero Therapeutics Inc Stock (SPRO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Rajavelu Esther
CFO & CBO
Feb 05 '25
Sale
0.78
20,689
16,137
724,720
Shukla Sath
CEO & President
Feb 05 '25
Sale
0.78
155,333
121,160
1,736,883
Mahadevia Ankit
Director
Feb 05 '25
Sale
0.78
69,219
53,991
689,866
Rajavelu Esther
CFO & CBO
Nov 07 '24
Sale
1.31
23,351
30,590
396,515
Rajavelu Esther
CFO & CBO
Nov 08 '24
Sale
1.30
17,245
22,418
379,270
Mahadevia Ankit
Director
Aug 27 '24
Sale
1.35
5,912
7,981
759,085
Keutzer Timothy
Chief Operating Officer
Aug 27 '24
Sale
1.35
2,213
2,988
531,837
Shukla Sath
CEO & President
Aug 27 '24
Sale
1.35
2,757
3,722
1,140,809
Shukla Sath
CEO and President
Aug 05 '24
Sale
1.31
17,641
23,110
1,143,566
Shukla Sath
CEO and President
Aug 02 '24
Sale
1.32
14,800
19,536
1,161,207
$20.04
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biotechnology ONC
$230.98
price up icon 1.24%
Cap:     |  Volume (24h):