2.13
price down icon9.36%   -0.22
after-market After Hours: 2.19 0.06 +2.82%
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Spero Therapeutics Inc stock is traded at $2.13, with a volume of 7.26M. It is down -9.36% in the last 24 hours and up +217.44% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$2.35
Open:
$2.23
24h Volume:
7.26M
Relative Volume:
2.42
Market Cap:
$119.09M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
213.00
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
+205.16%
1M Performance:
+217.44%
6M Performance:
+86.84%
1Y Performance:
+50.00%
1-Day Range:
Value
$2.10
$2.34
1-Week Range:
Value
$0.6562
$2.48
52-Week Range:
Value
$0.5052
$2.48

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

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SPRO
Spero Therapeutics Inc
2.13 39.03M 76.19M -1.61M 28.98M 0.01
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AKTX
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REGN
Regeneron Pharmaceuticals Inc
605.39 64.44B 14.09B 4.50B 2.96B 39.28
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VRNA
Verona Pharma Plc Adr
77.49 6.19B 0 -153.72M -103.81M -2.00

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
May 29, 2025

Spero Therapeutics Stock (SPRO) Rockets 225% on Clinical Trial Data - The Globe and Mail

May 29, 2025
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May 29, 2025

Spero Therapeutics Jumps as Oral Carbapenem Hits Phase 3 Milestone - Insider Monkey

May 29, 2025
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May 29, 2025

SPRO Stock Soars 245% on GSK-Partnered UTI Drug Meeting Study Goal - TradingView

May 29, 2025
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May 29, 2025

Spero Therapeutics And 2 Other Promising Penny Stocks To Watch - Yahoo Finance

May 29, 2025
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May 29, 2025

Spero Therapeutics rockets on positive Phase III study for tebipenem HBr - The Pharma Letter

May 29, 2025
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May 28, 2025

Biotech Finds Mid-Week Success After Meeting Primary Endpoint - The Globe and Mail

May 28, 2025
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May 28, 2025

GSK’s Bet On Spero’s Oral cUTI Antibiotic Poised To Pay Off With New Phase III Data - insights.citeline.com

May 28, 2025
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May 28, 2025

Spero Therapeutics (SPRO) Stock Explodes: Shares Skyrocket Over 200% in Stunning Midday Rally! - Daily Chhattisgarh News

May 28, 2025
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May 28, 2025

Why Is GSK Partner Spero Therapeutics Stock Skyrocketing On Wednesday? - Benzinga

May 28, 2025
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May 28, 2025

GSK, Spero stop UTI drug trial after early success - Reuters

May 28, 2025
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May 28, 2025

GSK, Spero Therapeutics Stop Antibiotic Trial For Complicated Urinary Tract Infections Early After Positive Results, Retail’s Thrilled By Stocktwits - Investing.com India

May 28, 2025
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May 28, 2025

Spero Therapeutics (SPRO) Soars 255% on Phase 3 Success - GuruFocus

May 28, 2025
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May 28, 2025

Spero Therapeutics stock soars on positive phase 3 trial results By Investing.com - Investing.com South Africa

May 28, 2025
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May 28, 2025

Spero Therapeutics stock soars on positive phase 3 trial results - Investing.com Australia

May 28, 2025
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May 28, 2025

Spero Therapeutics’ Phase 3 Trial Meets Primary Endpoint - TipRanks

May 28, 2025
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May 28, 2025

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study - GlobeNewswire

May 28, 2025
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May 28, 2025

Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study for Tebipenem HBr Stopped Early for Efficacy Following Review by Independent Data Monitoring Committee | SPRO Stock News - GuruFocus

May 28, 2025
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May 28, 2025

Breakthrough UTI Treatment Success: First-Ever Oral Carbapenem Shows Early Phase 3 Win in $6B Market - Stock Titan

May 28, 2025
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May 17, 2025

Analyzing Perrigo (NYSE:PRGO) & Spero Therapeutics (NASDAQ:SPRO) - Defense World

May 17, 2025
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May 15, 2025

Spero Therapeutics, Inc. (SPRO) Reports Q1 Loss, Misses Revenue Estimates - MSN

May 15, 2025
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May 14, 2025

Spero Therapeutics (SPRO) to Release Earnings on Wednesday - Defense World

May 14, 2025
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May 13, 2025

Spero Therapeutics Announces First Quarter 2025 Operating Results and Provides a Business Update - GlobeNewswire

May 13, 2025
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May 13, 2025

Spero Therapeutics Advances Phase 3 Trial With Strong Cash Position, Welcomes New CEO - Stock Titan

May 13, 2025
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May 13, 2025

SPERO THERAPEUTICS Earnings Results: $SPRO Reports Quarterly Earnings - Nasdaq

May 13, 2025
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May 13, 2025

Spero Therapeutics Inc (SPRO) Q1 2025: Everything You Need To Kn - GuruFocus

May 13, 2025
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May 07, 2025

Spero Therapeutics, Inc. (NASDAQ:SPRO) Shares Bought by JPMorgan Chase & Co. - Defense World

May 07, 2025
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May 05, 2025

Spero Therapeutics to Report First Quarter 2025 Financial Results and Provide Business Update on Tuesday, May 13, 2025 - The Manila Times

May 05, 2025
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May 05, 2025

Spero Therapeutics to Report First Quarter 2025 Financial - GlobeNewswire

May 05, 2025
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May 05, 2025

Spero Therapeutics to Report First Quarter 2025 Financial Results and Provide Business Update ... - Eagle-Tribune

May 05, 2025
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Apr 30, 2025

Renaissance Technologies LLC Increases Stake in Spero Therapeutics, Inc. (NASDAQ:SPRO) - Defense World

Apr 30, 2025
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Apr 28, 2025

Spero Therapeutics Appoints Esther Rajavelu as CEO - citybiz

Apr 28, 2025
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Apr 28, 2025

New Leadership Announcement for Spero Therapeutics (SPRO) | SPRO Stock News - GuruFocus

Apr 28, 2025
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Apr 28, 2025

Spero Therapeutics appoints new CEO and board nominee - Investing.com

Apr 28, 2025
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Apr 28, 2025

Spero Therapeutics Appoints Esther Rajavelu As President And Chief Executive Officer - marketscreener.com

Apr 28, 2025
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Apr 28, 2025

Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive Officer - GlobeNewswire

Apr 28, 2025
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Apr 28, 2025

Spero Therapeutics Promotes CFO to CEO Role as Critical Phase 3 Trial Results Approach - Stock Titan

Apr 28, 2025
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Apr 26, 2025

Spero Therapeutics, Inc. to Host Earnings Call - ACCESS Newswire

Apr 26, 2025
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Apr 12, 2025

Prudential Financial Inc. Acquires Shares of 49,200 Spero Therapeutics, Inc. (NASDAQ:SPRO) - Defense World

Apr 12, 2025
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Apr 09, 2025

Spero Therapeutics stock hits 52-week low at $0.51 amid challenges - Investing.com Canada

Apr 09, 2025
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Apr 09, 2025

Spero Therapeutics stock hits 52-week low at $0.51 amid challenges By Investing.com - Investing.com South Africa

Apr 09, 2025
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Apr 07, 2025

Bronstein, Gewirtz & Grossman, LLC Notifies Spero Therapeutics, Inc. (SPRO) Shareholders of Class Action and Encourages Investors to Contact the Firm - Business Wire

Apr 07, 2025
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Apr 05, 2025

Spero Therapeutics, Inc. CLASS ACTION Alert: Wolf Haldenstein Adler Freeman & Herz LLP announces that a securities class action lawsuit has been filed in the United States District Court for the Eastern District of New York against Spero Therapeutics, Inc. - MarketScreener

Apr 05, 2025
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Apr 02, 2025

Virtu Financial LLC Makes New $47,000 Investment in Spero Therapeutics, Inc. (NASDAQ:SPRO) - Defense World

Apr 02, 2025
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Mar 29, 2025

We're Keeping An Eye On Spero Therapeutics' (NASDAQ:SPRO) Cash Burn Rate - Yahoo Finance

Mar 29, 2025
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Mar 28, 2025

Earnings call transcript: Spero Therapeutics Q4 2024 misses EPS forecast - Investing.com India

Mar 28, 2025
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Mar 28, 2025

Spero Therapeutics Inc (SPRO) Q4 2024 Earnings Call Highlights: Navigating Financial Challenges ... - Yahoo

Mar 28, 2025
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Mar 28, 2025

Spero Therapeutics Inc (SPRO) Q4 2024 Earnings Call Highlights: - GuruFocus

Mar 28, 2025
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Mar 27, 2025

Earnings call transcript: Spero Therapeutics Q4 2024 misses EPS forecast By Investing.com - Investing.com South Africa

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics earnings missed by $0.02, revenue topped estimates - Investing.com Canada

Mar 27, 2025
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Mar 27, 2025

Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business Update - GlobeNewswire

Mar 27, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$1.06
price up icon 0.95%
$31.31
price up icon 3.40%
$580.95
price up icon 0.82%
$292.90
price up icon 2.57%
$4.64
price up icon 6.67%
$77.49
price up icon 4.82%
Cap:     |  Volume (24h):