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Spero Therapeutics Inc stock is traded at $2.30, with a volume of 518.73K. It is down -0.86% in the last 24 hours and down -20.69% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$2.32
Open:
$2.26
24h Volume:
518.73K
Relative Volume:
0.12
Market Cap:
$128.59M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
230.00
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
-1.29%
1M Performance:
-20.69%
6M Performance:
+168.50%
1Y Performance:
+65.47%
1-Day Range:
Value
$2.22
$2.325
1-Week Range:
Value
$2.16
$2.435
52-Week Range:
Value
$0.5052
$3.22

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SPRO
Spero Therapeutics Inc
2.30 129.71M 76.19M -1.61M 28.98M 0.01
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
462.13 117.32B 11.10B -988.90M -1.26B -3.92
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
558.87 58.89B 14.09B 4.50B 2.96B 39.28
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
401.80 51.14B 2.35B -269.70M -75.39M -2.09
Biotechnology icon
ARGX
Argen X Se Adr
673.80 41.02B 2.58B 1.06B -1.28B 16.33
Biotechnology icon
ONC
Beone Medicines Ltd Adr
299.01 32.59B 3.81B -644.79M -669.77M -6.24

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
02:56 AM

Trend analysis for Spero Therapeutics Inc. this weekSmart Chart Forecasting with AI Algorithms - Newser

02:56 AM
pulisher
Aug 01, 2025

Using Python tools to backtest Spero Therapeutics Inc. strategiesMomentum Trading Guide with Safety Limits - Newser

Aug 01, 2025
pulisher
Aug 01, 2025

Spero Therapeutics Inc. Breaks Losing Streak — Is the Trend ReversingProfit Target Stock Opportunity Monitor Activated - metal.it

Aug 01, 2025
pulisher
Aug 01, 2025

How hedge fund analytics apply to Spero Therapeutics Inc. stock7-Day Equity Return Range Forecast Model - Newser

Aug 01, 2025
pulisher
Aug 01, 2025

What momentum shifts mean for Spero Therapeutics Inc.Predictable Income Summary for Long-Term Trades - Newser

Aug 01, 2025
pulisher
Aug 01, 2025

Should I hold or sell Spero Therapeutics Inc. stock in 2025Value Investing Picks For Consistent Profits - jammulinksnews.com

Aug 01, 2025
pulisher
Jul 31, 2025

What is the risk reward ratio of investing in Spero Therapeutics Inc. stockPre Market Trend Scanner With High Returns - jammulinksnews.com

Jul 31, 2025
pulisher
Jul 31, 2025

How Spero Therapeutics Inc. stock performs during market volatilitySmart Trade Forecast Based on Neural Logic - Newser

Jul 31, 2025
pulisher
Jul 30, 2025

Spero Therapeutics Inc. Matches Institutional Buying FilterAccurate Buy Point for Momentum Stocks Detected - metal.it

Jul 30, 2025
pulisher
Jul 29, 2025

What makes Spero Therapeutics Inc. stock price move sharplyFree Real Time Stock Movement Analysis - Newser

Jul 29, 2025
pulisher
Jul 29, 2025

Multi factor analysis applied to Spero Therapeutics Inc.Free Weekly Setup With 3x Return Potential - Newser

Jul 29, 2025
pulisher
Jul 29, 2025

Can Spero Therapeutics Inc. Regain Momentum After BreakdownWeekly Top Gainers Forecast Watchlist Released - beatles.ru

Jul 29, 2025
pulisher
Jul 29, 2025

Spero Therapeutics Inc. Stock Support and Resistance Levels You Should KnowFree AI Based High Gain Watchlist Scanner - Newser

Jul 29, 2025
pulisher
Jul 29, 2025

Will Spero Therapeutics Inc. stock benefit from AI tech trendsAI Triggered Buy Zone Forecast System - Newser

Jul 29, 2025
pulisher
Jul 28, 2025

Why is Spero Therapeutics Inc. stock attracting strong analyst attentionSwing Trade Review With Proven Results - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 28, 2025

When is Spero Therapeutics Inc. stock expected to show significant growthOutstanding investment returns - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 28, 2025

How does Spero Therapeutics Inc. generate profit in a changing economyFree Investment Risk Control - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 27, 2025

How volatile is Spero Therapeutics Inc. stock compared to the marketExponentially increasing returns - jammulinksnews.com

Jul 27, 2025
pulisher
Jul 27, 2025

Is Spero Therapeutics Inc. stock overvalued or undervaluedExceptional market performance - jammulinksnews.com

Jul 27, 2025
pulisher
Jul 27, 2025

What institutional investors are buying Spero Therapeutics Inc. stockMaximize returns with effective portfolio management - jammulinksnews.com

Jul 27, 2025
pulisher
Jul 27, 2025

What is the dividend policy of Spero Therapeutics Inc. stockGet real-time alerts on top-performing stocks - jammulinksnews.com

Jul 27, 2025
pulisher
Jul 25, 2025

What drives Spero Therapeutics Inc. stock priceTremendous portfolio expansion - PrintWeekIndia

Jul 25, 2025
pulisher
Jul 25, 2025

Is Spero Therapeutics Inc. a good long term investmentExceptional market positioning - PrintWeekIndia

Jul 25, 2025
pulisher
Jul 25, 2025

What risks could impact Spero Therapeutics Inc. stock performanceConsistently high yield - jammulinksnews.com

Jul 25, 2025
pulisher
Jul 25, 2025

What institutions are buying Spero Therapeutics Inc. stock nowBreakneck growth rates - jammulinksnews.com

Jul 25, 2025
pulisher
Jul 25, 2025

Why Spero Therapeutics Inc. stock is on top investor watchlistsOutstanding capital appreciation - jammulinksnews.com

Jul 25, 2025
pulisher
Jul 24, 2025

What analysts say about Spero Therapeutics Inc. stockSuperior portfolio returns - Autocar Professional

Jul 24, 2025
pulisher
Jul 24, 2025

Published on: 2025-07-24 21:52:51 - jammulinksnews.com

Jul 24, 2025
pulisher
Jul 22, 2025

Spero Therapeutics Inc. Stock Analysis and ForecastConsistently superior profits - jammulinksnews.com

Jul 22, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$75.59
price up icon 0.93%
$37.11
price up icon 0.84%
$108.69
price up icon 1.31%
$27.07
price up icon 2.65%
$107.34
price down icon 0.15%
biotechnology ONC
$299.01
price down icon 0.70%
Cap:     |  Volume (24h):