1.90
price down icon2.56%   -0.05
after-market After Hours: 1.93 0.03 +1.58%
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Spero Therapeutics Inc stock is traded at $1.90, with a volume of 391.23K. It is down -2.56% in the last 24 hours and down -19.49% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$1.95
Open:
$1.96
24h Volume:
391.23K
Relative Volume:
0.45
Market Cap:
$106.92M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
190.00
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
-11.63%
1M Performance:
-19.49%
6M Performance:
+153.81%
1Y Performance:
+42.86%
1-Day Range:
Value
$1.89
$1.9883
1-Week Range:
Value
$1.86
$2.18
52-Week Range:
Value
$0.5052
$3.22

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SPRO
Spero Therapeutics Inc
1.90 109.17M 76.19M -1.61M 28.98M 0.01
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
394.53 99.62B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
465.89 61.52B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
560.00 58.91B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ARGX
Argen X Se Adr
756.38 46.69B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
324.34 34.54B 3.81B -644.79M -669.77M -6.24

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
Sep 12, 2025

Will Spero Therapeutics Inc. stock outperform tech sector in 2025July 2025 Setups & Free Daily Entry Point Trade Alerts - baoquankhu1.vn

Sep 12, 2025
pulisher
Sep 11, 2025

Spero Therapeutics, Inc. (NASDAQ:SPRO) Short Interest Down 32.8% in August - MarketBeat

Sep 11, 2025
pulisher
Sep 09, 2025

Does Spero Therapeutics Inc. have pricing powerQuarterly Trade Review & Low Risk Growth Stock Ideas - Lancaster City Council

Sep 09, 2025
pulisher
Sep 09, 2025

What is Spero Therapeutics Inc.’s valuation compared to sector2025 Market WrapUp & AI Based Buy/Sell Signal Reports - Lancaster City Council

Sep 09, 2025
pulisher
Sep 08, 2025

Will Spero Therapeutics Inc. outperform its industry peersMarket Performance Recap & Weekly Consistent Profit Watchlists - beatles.ru

Sep 08, 2025
pulisher
Sep 08, 2025

Spero Therapeutics (NASDAQ:SPRO) Director Sells $12,946.84 in Stock - MarketBeat

Sep 08, 2025
pulisher
Sep 07, 2025

Should you buy the dip on Spero Therapeutics Inc.2025 Breakouts & Breakdowns & Smart Allocation Stock Reports - beatles.ru

Sep 07, 2025
pulisher
Sep 07, 2025

Is Spero Therapeutics Inc. a good stock for dollar cost averaging2025 Growth vs Value & Low Drawdown Trading Strategies - beatles.ru

Sep 07, 2025
pulisher
Sep 06, 2025

Multi asset correlation models including Spero Therapeutics Inc.Weekly Trade Recap & Risk Controlled Swing Trade Alerts - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Sentiment analysis tools applied to Spero Therapeutics Inc.2025 Earnings Impact & Reliable Price Action Trade Plans - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Signal strength of Spero Therapeutics Inc. stock in tech scannersDip Buying & Free Fast Entry Momentum Trade Alerts - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Can Spero Therapeutics Inc. lead its sector in growthJuly 2025 Weekly Recap & Weekly Top Stock Performers List - خودرو بانک

Sep 06, 2025
pulisher
Sep 05, 2025

Why Spero Therapeutics Inc. is moving todayWeekly Stock Analysis & Community Consensus Picks - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Analyzing recovery setups for Spero Therapeutics Inc. investors2025 Price Targets & Weekly Stock Breakout Alerts - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

How sentiment analysis helps forecast Spero Therapeutics Inc.Sell Signal & Verified Stock Trade Ideas - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Is Spero Therapeutics Inc. exposed to currency risksQuarterly Market Review & Risk Controlled Daily Trade Plans - خودرو بانک

Sep 05, 2025
pulisher
Sep 05, 2025

Ranking Spero Therapeutics Inc. among high performing stocks via toolsMarket Movement Recap & Safe Entry Zone Identification - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Is Spero Therapeutics Inc. a candidate for recovery playGap Down & Weekly Watchlist for Hot Stocks - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Technical signs of recovery in Spero Therapeutics Inc.Weekly Gains Summary & Daily Chart Pattern Signals - Newser

Sep 05, 2025
pulisher
Sep 04, 2025

What candlestick patterns are forming on Spero Therapeutics Inc.Quarterly Profit Summary & Verified Momentum Stock Alerts - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Comparing Spero Therapeutics Inc. in custom built stock radarsJuly 2025 Earnings & Low Risk Entry Point Guides - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Trend analysis for Spero Therapeutics Inc. this weekEntry Point & AI Forecasted Entry/Exit Points - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Risk vs reward if holding onto Spero Therapeutics Inc.July 2025 Spike Watch & Growth Focused Stock Reports - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Using data models to predict Spero Therapeutics Inc. stock movementMarket Risk Report & Free High Accuracy Swing Entry Alerts - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Live market analysis of Spero Therapeutics Inc.Weekly Gains Report & Risk Controlled Stock Pick Alerts - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

What data driven models say about Spero Therapeutics Inc.’s futureInflation Watch & Verified Short-Term Trading Plans - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Price momentum metrics for Spero Therapeutics Inc. explained2025 Technical Patterns & Long-Term Safe Investment Plans - Newser

Sep 04, 2025
pulisher
Sep 03, 2025

Spero therapeutics (SPRO): COO Keutzer sells $3.3k in stock - Investing.com India

Sep 03, 2025
pulisher
Sep 03, 2025

Mahadevia Ankit sells Spero Therapeutics (SPRO) stock worth $12946 By Investing.com - Investing.com Canada

Sep 03, 2025
pulisher
Sep 03, 2025

Is Spero Therapeutics Inc. subject to activist investor interestWeekly Risk Report & Real-Time Volume Trigger Notifications - خودرو بانک

Sep 03, 2025
pulisher
Sep 03, 2025

Spero Therapeutics Inc. stock chart pattern explained2025 Year in Review & Momentum Based Trading Ideas - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Earnings visualization tools for Spero Therapeutics Inc.July 2025 Fed Impact & Expert Approved Momentum Trade Ideas - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Published on: 2025-09-03 19:52:17 - beatles.ru

Sep 03, 2025
pulisher
Sep 03, 2025

Aug Drivers: Can Spero Therapeutics Inc. lead its sector in growthTrade Performance Summary & Step-by-Step Swing Trade Plans - خودرو بانک

Sep 03, 2025
pulisher
Sep 03, 2025

Mahadevia Ankit sells Spero Therapeutics (SPRO) stock worth $12946 - Investing.com

Sep 03, 2025
pulisher
Sep 03, 2025

What institutional flow reveals about Spero Therapeutics Inc.2025 Trade Ideas & Consistent Growth Equity Picks - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Spero therapeutics (SPRO): COO Keutzer sells $3.3k in stock By Investing.com - Investing.com UK

Sep 03, 2025
pulisher
Sep 03, 2025

Custom strategy builders for tracking Spero Therapeutics Inc.2025 Support & Resistance & Low Risk High Reward Trade Ideas - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Applying sector rotation models to Spero Therapeutics Inc.2025 Historical Comparison & Reliable Trade Execution Plans - Newser

Sep 03, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$36.36
price down icon 0.93%
$83.10
price down icon 3.56%
$27.82
price down icon 2.76%
$96.74
price down icon 7.26%
$145.93
price up icon 0.10%
biotechnology ONC
$324.34
price down icon 3.38%
Cap:     |  Volume (24h):