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Seaport Therapeutics Inc stock is traded at $17.55, with a volume of 92,544. It is up +5.25% in the last 24 hours and down -23.54% over the past month. Seaport Therapeutics Inc is a clinical-stage therapeutics company. The company focuses on invention and development of new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. The company identified clinically validated mechanisms with established efficacy and safety profiles, historically limited by high first-pass metabolism, low bioavailability, and side effects. The company's pipeline products are based on Glyph, company's lymphatic-targeting prodrug technology is designed to bypass first-pass metabolism and thereby enhance a drug's oral bioavailability and reduce side effects.
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Previous Close:
$16.68
Open:
$16.82
24h Volume:
92,544
Relative Volume:
0.43
Market Cap:
$939.73M
Revenue:
Net Income/Loss:
P/E Ratio:
-24.39
EPS:
-0.7198
Net Cash Flow:
1W Performance:
-1.98%
1M Performance:
-23.54%
6M Performance:
+0.00%
1Y Performance:
+0.00%
1-Day Range:
Value
$16.61
$17.89
1-Week Range:
Value
$15.79
$18.79
52-Week Range:
Value
$14.85
$28.38

Seaport Therapeutics Inc Stock (SPTX) Company Profile

Name
Name
Seaport Therapeutics Inc
Name
Phone
617-807-4062
Name
Address
6 TIDE STREET, BOSTON
Name
Employee
54
Name
Twitter
Name
Next Earnings Date
2026-11-02
Name
Latest SEC Filings
Name
SPTX's Discussions on Twitter

Compare SPTX vs VRTX, MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
SPTX icon
SPTX
Seaport Therapeutics Inc
17.55 939.73M 0 0 0 -0.7198
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
508.46 128.88B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
237.99 95.01B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
800.59 82.42B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
849.61 53.43B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
372.06 42.09B 5.76B 514.49M 1.10B 4.4813

Seaport Therapeutics Inc Stock (SPTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-25-26 Initiated Raymond James Strong Buy
Jul-15-26 Initiated H.C. Wainwright Buy
May-26-26 Initiated Citigroup Buy
May-26-26 Initiated JP Morgan Overweight
May-26-26 Initiated Leerink Partners Outperform
May-26-26 Initiated Stifel Buy
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Seaport Therapeutics Inc Stock (SPTX) Latest News

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Oct 09, 2026

Seaport reports 6.8-fold GlyphAgo bioavailability increase - grafa.com

Oct 09, 2026
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Oct 07, 2026

Seaport Therapeutics (NASDAQ:SPTX) Shares Up 3.6%Here's Why - MarketBeat

Oct 07, 2026
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Oct 01, 2026

Seaport Therapeutics (NASDAQ:SPTX) Shares Gap UpWhat's Next? - MarketBeat

Oct 01, 2026
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Sep 28, 2026

Seaport Therapeutics, Inc. (NASDAQ:SPTX) Stock Has Consensus Target Price of $38.57 - MarketBeat

Sep 28, 2026
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Sep 28, 2026

Seaport Therapeutics (NASDAQ:SPTX) Stock Price Down 6.3%Here's What Happened - MarketBeat

Sep 28, 2026
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Sep 27, 2026

Seaport Therapeutics, Inc. $SPTX Shares Newly Acquired by State Street Corp - MarketBeat

Sep 27, 2026
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Sep 25, 2026

Seaport Therapeutics (NASDAQ:SPTX) Shares Gap UpHere's Why - MarketBeat

Sep 25, 2026
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Sep 25, 2026

Raymond James initiates Seaport Therapeutics stock coverage with strong buy on depression drug potential - Investing.com

Sep 25, 2026
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Sep 22, 2026

Seaport Therapeutics, Inc. (SPTX) stock price, news, quote and history - uk.finance.yahoo.com

Sep 22, 2026
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Sep 14, 2026

The Manufacturers Life Insurance Company Acquires New Stake in Seaport Therapeutics, Inc. $SPTX - marketbeat.com

Sep 14, 2026
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Sep 11, 2026

Analysts Conflicted on These NA Names: SailPoint, Inc. (SAIL) and Seaport Therapeutics, Inc. (SPTX) - theglobeandmail.com

Sep 11, 2026
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Sep 11, 2026

Analysts Conflicted on These NA Names: SailPoint, Inc. (SAIL) and Seaport Therapeutics, Inc. (SPTX) - theglobeandmail.com

Sep 11, 2026
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Sep 10, 2026

Seaport Therapeutics (NASDAQ:SPTX) Stock Price Up 4.6%Should You Buy? - MarketBeat

Sep 10, 2026
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Sep 10, 2026

HC Wainwright Reaffirms Buy Rating for Seaport Therapeutics (NASDAQ:SPTX) - MarketBeat

Sep 10, 2026
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Sep 09, 2026

PureTech Founded Entity Seaport Therapeutics Reports Positive Topline Results from Phase 1 Driving Simulation Trial of GlyphAllo™ in Healthy Volunteers - biospace.com

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics at citigroup’s biopharma back to school summit 2026: platform push - Investing.com Canada

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics reports positive phase 1 trial results - investing.com

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics, Inc.Common Stock (Nasdaq:SPTX) Stock Quote - FinancialContent

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics reports positive phase 1 trial results By Investing.com - Investing.com Canada

Sep 09, 2026
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Sep 09, 2026

PureTech Says Seaport Therapeutics Reports Positive Phase 1 Driving Trial Results for GlyphAllo - TradingView

Sep 09, 2026
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Sep 09, 2026

PureTech Founded Entity Seaport Therapeutics Reports Positive Topline Results from Phase 1 Driving Simulation Trial of GlyphAllo™ in Healthy Volunteers - Yahoo Finance

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics reports positive phase 1 trial results By Investing.com - Investing.com UK

Sep 09, 2026
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Sep 09, 2026

RCSPureTech Health PLCPRTC's SPTX: New Positive Phase 1 GlyphAllo Data - TradingView

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics Says GlyphAllo Shows no Next-Morning Driving Impairment in Phase 1 Trial - marketscreener.com

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics Reports Positive Topline Results from Phase 1 Driving Simulation Trial of GlyphAllo™ in Healthy Volunteers - Business Wire

Sep 09, 2026
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Sep 09, 2026

Seaport Therapeutics Reports Positive Topline Results from Phase 1 Driving Simulation Trial of GlyphAllo™ in Healthy Volunteers - Yahoo Finance

Sep 09, 2026
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Sep 09, 2026

A 375 mg dose did not impair next-morning driving in a Seaport trial - Stock Titan

Sep 09, 2026
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Sep 08, 2026

Citadel Advisors LLC Takes Position in Seaport Therapeutics, Inc. $SPTX - MarketBeat

Sep 08, 2026
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Sep 03, 2026

Braidwell LP Takes $10.86 Million Position in Seaport Therapeutics, Inc. $SPTX - MarketBeat

Sep 03, 2026
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Sep 03, 2026

Seaport Therapeutics, Inc. (NASDAQ:SPTX) Given Consensus Rating of "Hold" by Analysts - marketbeat.com

Sep 03, 2026
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Sep 02, 2026

Alyeska Investment Group L.P. Makes New $1.63 Million Investment in Seaport Therapeutics, Inc. $SPTX - MarketBeat

Sep 02, 2026
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Aug 31, 2026

Seaport Therapeutics, Inc. Common Stock (NASDAQ: SPTX) Stock Price, News & Analysis - kalkine.ca

Aug 31, 2026
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Aug 31, 2026

Seaport Therapeutics to Present at Citi’s 2026 Biopharma Back to School Conference and Participate in 21st Annual Wells Fargo Healthcare Conference - BioSpace

Aug 31, 2026
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Aug 31, 2026

Seaport Therapeutics to Present at Citi’s 2026 Biopharma Back to School Conference and Participate in 21st Annual Wells Fargo Healthcare Conference - Yahoo Finance UK

Aug 31, 2026
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Aug 31, 2026

Seaport Therapeutics to Present at Citi’s 2026 Biopharma Back to School Conference and Participate in 21st Annual Wells Fargo Healthcare Conference - Yahoo Finance

Aug 31, 2026
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Aug 27, 2026

Seaport Therapeutics (NASDAQ:SPTX) Stock Price Down 5.2%Here's Why - MarketBeat

Aug 27, 2026
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Aug 26, 2026

Seaport Therapeutics (NASDAQ:SPTX) Now Covered by Analysts at JonesTrading - MarketBeat

Aug 26, 2026
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Aug 24, 2026

Seaport Therapeutics (NASDAQ:SPTX) Sets New 52-Week HighHere's Why - MarketBeat

Aug 24, 2026
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Aug 20, 2026

Why Bristol Myers, Johnson & Johnson and More Are Watching Seaport After IPO - 24/7 Wall St.

Aug 20, 2026
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Aug 20, 2026

Seaport Therapeutics' (SPTX) Buy Rating Reaffirmed at HC Wainwright - MarketBeat

Aug 20, 2026
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Aug 20, 2026

H.C. Wainwright reiterates Seaport Therapeutics stock rating at buy By Investing.com - Investing.com Canada

Aug 20, 2026
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Aug 20, 2026

Selvaraju Reiterates Buy on Seaport, Citing Differentiated Neuropsychiatry Pipeline and Unchanged $50 Price Target - TipRanks

Aug 20, 2026
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Aug 19, 2026

Trv Gp Vi LLC Acquires New Shares in Seaport Therapeutics, Inc. $SPTX - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Seaport Therapeutics, Inc.: Target Price Consensus and Analysts Recommendations | SPTX | US81221K1088 - marketscreener.com

Aug 19, 2026
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Aug 18, 2026

Seaport Therapeutics (NASDAQ:SPTX) Reaches New 52-Week HighHere's What Happened - MarketBeat

Aug 18, 2026
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Aug 14, 2026

PureTech Health (SPTX holder) discloses 31.2% Seaport Therapeutics stake - Stock Titan

Aug 14, 2026
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Aug 13, 2026

Stifel Maintains Seaport Therapeutics(SPTX.US) With Buy Rating, Maintains Target Price $30 - Moomoo

Aug 13, 2026
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Aug 12, 2026

Seaport Therapeutics (NASDAQ:SPTX) Reaches New 52-Week HighHere's What Happened - MarketBeat

Aug 12, 2026
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Aug 11, 2026

Seaport Therapeutics, Inc. Common Stock (NASDAQ: SPTX) Stock Price, News & Analysis - kalkine.com.au

Aug 11, 2026
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Aug 11, 2026

Seaport Therapeutics: A Development-Arbitrage Platform With Two Layers Of Validation - Seeking Alpha

Aug 11, 2026

Seaport Therapeutics Inc Stock (SPTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Seaport Therapeutics Inc Stock (SPTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ARCH Venture Partners XII, LLC
10% Owner
May 04 '26
Buy
18.00
1,100,000
19,800,000
6,294,951
$1.68
price up icon 8.39%
$9.75
price up icon 3.61%
$14.00
price down icon 10.88%
$4.755
price down icon 0.11%
$22.66
price up icon 4.40%
$13.75
price up icon 0.81%
Cap:     |  Volume (24h):