Upstream Bio Inc (UPB)

Overview News Price History Option Chain Financials Discussions Forecast

Upstream Bio Inc Stock (UPB) Price History

The historical daily chart and data for Upstream Bio Inc stock (UPB), show that the latest closing stock price as of October 15, 2026, is $3.375.

Upstream Bio Inc all-time high stock price is $33.68, occurred on January 14, 2026.
The lowest Upstream Bio Inc stock price recorded was $3.29 on October 14, 2026. Since then, Upstream Bio Inc's stock price has risen over 2.58% to $3.375 now.
The 52-week high stock price for UPB is $33.68, representing a 897.93% increase from the current share price, occurred on January 14, 2026.
The 52-week low stock price for UPB is $3.29, indicating a -2.52% decrease from the current share price, occurred on October 14, 2026.
The closing price of Upstream Bio Inc (UPB) stock in the beginning of 2025 was $16.30. The stock closed the year at $27.15, a gain of over 66.56% for the year.

The table below shows more information about UPB historical price data:

Daily

Weekly

Monthly

30D

60D

YTD

Date	High	Low	High - Low	Volume	% Change
Oct 15, 2026	$3.56	$3.29	$0.27	1,018,379.0	-1.32%
Oct 14, 2026	$3.60	$3.29	$0.31	1,574,473.0	-3.66%
Oct 13, 2026	$4.16	$3.52	$0.635	1,037,524.0	-14.87%
Oct 12, 2026	$4.72	$4.12	$0.60	848,408.0	-11.28%
Oct 09, 2026	$4.76	$4.51	$0.25	1,187,831.0	+3.30%
Oct 08, 2026	$4.65	$4.37	$0.285	2,857,189.0	-1.30%
Oct 07, 2026	$4.72	$4.50	$0.22	908,403.0	+0.44%
Oct 06, 2026	$4.87	$4.53	$0.335	1,062,306.0	-5.36%
Oct 05, 2026	$5.10	$4.67	$0.435	1,010,579.0	-3.77%
Oct 02, 2026	$5.21	$4.86	$0.35	956,520.0	+0.00%
Oct 01, 2026	$5.34	$4.98	$0.365	832,378.0	-4.36%
Sep 30, 2026	$5.46	$5.14	$0.31	851,222.0	+1.54%
Sep 29, 2026	$5.30	$4.99	$0.315	784,210.0	-2.08%
Sep 28, 2026	$5.38	$5.12	$0.265	615,403.0	-1.12%
Sep 25, 2026	$5.39	$5.07	$0.32	429,212.0	+3.68%
Sep 24, 2026	$5.20	$5.04	$0.155	566,582.0	-0.39%
Sep 23, 2026	$5.49	$4.99	$0.505	552,994.0	-5.46%
Sep 22, 2026	$5.56	$5.38	$0.18	360,533.0	+2.33%
Sep 21, 2026	$5.44	$5.27	$0.17	364,034.0	+0.47%
Sep 18, 2026	$5.41	$5.21	$0.20	1,000,981.0	+0.56%
Sep 17, 2026	$5.48	$5.24	$0.245	533,870.0	-0.38%
Sep 16, 2026	$5.54	$5.27	$0.27	497,239.0	-2.74%
Sep 15, 2026	$5.81	$5.46	$0.355	421,157.0	-5.68%

Upstream Bio Inc Stock (UPB) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Upstream Bio Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of UPB shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Upstream Bio Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Upstream Bio Inc Stock (UPB) Price History 2026

Month	High	Low	High - Low	Volume	% Change
Oct, 2026	$5.34	$3.29	$2.06	13,293,990.0	-35.96%
Sep, 2026	$6.98	$4.99	$2.00	13,091,436.0	-20.39%
Aug, 2026	$7.70	$6.17	$1.53	13,419,093.0	+4.91%
Jul, 2026	$8.00	$6.09	$1.91	10,296,647.0	-8.82%
Jun, 2026	$8.64	$5.85	$2.79	15,250,716.0	-17.22%
May, 2026	$9.60	$7.99	$1.61	10,271,388.0	-8.93%
Apr, 2026	$10.67	$8.96	$1.71	12,113,945.0	+2.00%
Mar, 2026	$10.43	$7.25	$3.18	22,603,021.0	+17.19%
Feb, 2026	$32.38	$7.62	$24.76	44,951,937.0	-75.29%
Jan, 2026	$33.68	$25.00	$8.68	12,435,765.0	+14.48%

Upstream Bio Inc Stock (UPB) Price History 2025

Month	High	Low	High - Low	Volume	% Change
Dec, 2025	$30.89	$24.61	$6.28	12,118,113.0	-4.48%
Nov, 2025	$33.00	$21.98	$11.02	8,784,413.0	+10.64%
Oct, 2025	$26.90	$18.05	$8.85	8,125,871.0	+37.43%
Sep, 2025	$21.03	$15.55	$5.48	12,893,529.0	+9.81%
Aug, 2025	$19.37	$14.21	$5.16	9,057,642.0	+11.89%
Jul, 2025	$16.15	$10.54	$5.61	8,863,349.0	+39.44%
Jun, 2025	$12.10	$9.25	$2.85	10,827,671.0	+18.96%
May, 2025	$9.90	$7.79	$2.11	8,016,902.0	-0.32%
Apr, 2025	$10.50	$5.14	$5.36	6,329,494.0	+51.31%
Mar, 2025	$10.08	$6.12	$3.96	5,002,930.0	-22.82%
Feb, 2025	$10.65	$6.65	$4.00	4,866,797.0	-26.37%
Jan, 2025	$18.95	$9.29	$9.66	4,964,040.0	-34.49%