20.08
price up icon2.34%   0.46
after-market After Hours: 20.08
loading
Upstream Bio Inc stock is traded at $20.08, with a volume of 218.21K. It is up +2.34% in the last 24 hours and up +14.29% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
See More
Previous Close:
$19.62
Open:
$19.79
24h Volume:
218.21K
Relative Volume:
0.46
Market Cap:
$1.08B
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-15.63
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
+5.85%
1M Performance:
+14.29%
6M Performance:
+172.46%
1Y Performance:
+0.00%
1-Day Range:
Value
$19.56
$20.31
1-Week Range:
Value
$18.18
$20.68
52-Week Range:
Value
$5.14
$29.46

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
UPB
Upstream Bio Inc
20.08 1.06B 2.22M -40.51M -46.53M -1.2847
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
407.37 104.55B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
464.95 60.36B 2.46B -319.09M -52.09M -2.4669
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
557.73 59.84B 14.21B 4.46B 3.56B 39.69
Biotechnology icon
ARGX
Argen X Se Adr
799.56 49.07B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ONC
Beone Medicines Ltd Adr
327.03 35.16B 4.56B -176.77M 225.30M -1.7177

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform

Upstream Bio Inc Stock (UPB) Latest News

pulisher
11:32 AM

What to do if you’re stuck in Upstream Bio Inc.July 2025 Technicals & Real-Time Volume Analysis Alerts - newser.com

11:32 AM
pulisher
10:10 AM

How resilient is Upstream Bio Inc. stock in market downturnsQuarterly Profit Summary & Real-Time Buy Zone Alerts - newser.com

10:10 AM
pulisher
09:15 AM

Will Upstream Bio Inc. stock outperform growth indexesFed Meeting & Technical Confirmation Alerts - newser.com

09:15 AM
pulisher
08:46 AM

Is Upstream Bio Inc. stock trading at a premium valuationJuly 2025 Catalysts & Entry and Exit Point Strategies - newser.com

08:46 AM
pulisher
08:12 AM

What earnings revisions data tells us about Upstream Bio Inc.2025 Earnings Surprises & Stepwise Trade Signal Implementation - newser.com

08:12 AM
pulisher
02:24 AM

Can Upstream Bio Inc. stock sustain revenue growthMarket Activity Summary & Risk Controlled Swing Trade Alerts - newser.com

02:24 AM
pulisher
Oct 09, 2025

Upstream Bio's (UPB) Sell (D-) Rating Reaffirmed at Weiss Ratings - MarketBeat

Oct 09, 2025
pulisher
Oct 09, 2025

Will Rising Interest Rates Hurt Vintage Coffee and Beverages Limiteds Profit MarginsMonthly Performance Summary & Free Stop-Loss Planning for Your Portfolio - earlytimes.in

Oct 09, 2025
pulisher
Oct 09, 2025

Measuring Upstream Bio Inc.’s beta against major indicesJuly 2025 News Drivers & Risk Adjusted Buy/Sell Alerts - newser.com

Oct 09, 2025
pulisher
Oct 09, 2025

What does recent volatility data suggest for Upstream Bio Inc.Weekly Profit Analysis & Stepwise Entry and Exit Trade Signals - newser.com

Oct 09, 2025
pulisher
Oct 07, 2025

What drives Upstream Bio Inc stock priceVolume Weighted Average Price & Plan Your Future With Strategic Investing - earlytimes.in

Oct 07, 2025
pulisher
Oct 06, 2025

Visualizing Upstream Bio Inc. stock with heatmapsJuly 2025 Rallies & Technical Analysis for Trade Confirmation - newser.com

Oct 06, 2025
pulisher
Oct 05, 2025

Can volume confirm reversal in Upstream Bio Inc.Trade Entry Report & AI Forecasted Entry/Exit Points - newser.com

Oct 05, 2025
pulisher
Oct 05, 2025

Applying Elliott Wave Theory to Upstream Bio Inc.July 2025 Setups & Daily Stock Trend Watchlist - newser.com

Oct 05, 2025
pulisher
Oct 04, 2025

Upstream Bio (UPB): Assessing Valuation as Shares Climb 7% Over the Past Week - Yahoo

Oct 04, 2025
pulisher
Oct 03, 2025

Assessing Upstream Bio (UPB) Valuation After New Verekitug Phase 2 Data and Investor Interest Surge - Sahm

Oct 03, 2025
pulisher
Oct 03, 2025

Upstream Bio, Inc. (NASDAQ:UPB) Receives Consensus Recommendation of "Buy" from Brokerages - MarketBeat

Oct 03, 2025
pulisher
Oct 03, 2025

Why Upstream Bio (UPB) Is Up 14.0% After Positive Phase 2 Verekitug Data and Novel Dosing Approach - Sahm

Oct 03, 2025
pulisher
Oct 03, 2025

News impact scoring models applied to Upstream Bio Inc.2025 Top Decliners & Safe Capital Growth Trade Ideas - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Is Upstream Bio Inc. forming a reversal patternJuly 2025 Update & Community Supported Trade Ideas - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Is Upstream Bio Inc. stock attractive for passive investorsMarket Growth Summary & AI Driven Stock Price Forecasts - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Earnings visualization tools for Upstream Bio Inc.July 2025 Earnings & Trade Opportunity Analysis - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Why retail investors pile into Upstream Bio Inc. stock2025 Market Outlook & Intraday High Probability Setup Alerts - newser.com

Oct 03, 2025
pulisher
Oct 02, 2025

Upstream Bio Inc Stock Analysis and ForecastPrice Channel Trading & Free Popular Stock Picks Selection - earlytimes.in

Oct 02, 2025
pulisher
Oct 01, 2025

Is Upstream Bio Inc. building a consolidation baseTrade Analysis Summary & Scalable Portfolio Growth Ideas - newser.com

Oct 01, 2025
pulisher
Sep 30, 2025

Upstream Bio (NASDAQ:UPB) Trading 4.2% HigherStill a Buy? - MarketBeat

Sep 30, 2025
pulisher
Sep 30, 2025

Upstream Bio Presents Data Showing Structural and Mechanistic Drivers of Verekitug’s Potent Pharmacodynamic Activity and Differentiated Clinical Profile at European Respiratory Society Congress - The Manila Times

Sep 30, 2025
pulisher
Sep 30, 2025

Upstream Bio Presents Data Showing Structural and - GlobeNewswire

Sep 30, 2025
pulisher
Sep 30, 2025

24-Week TSLP Inhibition: Upstream Bio's Verekitug Shows Breakthrough Respiratory Disease Treatment Data - Stock Titan

Sep 30, 2025
pulisher
Sep 29, 2025

Upstream Bio, Inc. $UPB Shares Sold by Goldman Sachs Group Inc. - Defense World

Sep 29, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Upstream Bio Inc Stock (UPB) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Oct 15 '24
Buy
17.00
825,000
14,025,000
4,554,873
AI Upstream LLC
10% Owner
Oct 15 '24
Buy
17.00
1,175,000
19,975,000
1,175,000
$84.73
price up icon 1.11%
$22.93
price up icon 7.40%
$32.68
price up icon 2.73%
$102.30
price up icon 0.24%
$163.94
price up icon 0.99%
biotechnology ONC
$327.03
price up icon 2.16%
Cap:     |  Volume (24h):