17.57
price down icon1.95%   -0.35
after-market After Hours: 17.57
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Upstream Bio Inc stock is traded at $17.57, with a volume of 282.43K. It is down -1.95% in the last 24 hours and up +0.40% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
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Previous Close:
$17.92
Open:
$18
24h Volume:
282.43K
Relative Volume:
0.57
Market Cap:
$947.19M
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-13.68
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
-12.02%
1M Performance:
+0.40%
6M Performance:
+90.36%
1Y Performance:
+0.00%
1-Day Range:
Value
$17.54
$18.11
1-Week Range:
Value
$17.02
$20.32
52-Week Range:
Value
$5.14
$29.46

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
UPB
Upstream Bio Inc
17.57 959.59M 2.22M -40.51M -46.53M -1.2847
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
394.53 99.62B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
465.89 61.52B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
560.00 58.91B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ARGX
Argen X Se Adr
756.38 46.69B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
324.34 34.54B 3.81B -644.79M -669.77M -6.24

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform

Upstream Bio Inc Stock (UPB) Latest News

pulisher
Sep 12, 2025

Is Upstream Bio Inc. stock reversal real or fakeMarket Trend Review & Real-Time Market Sentiment Reports - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Real time alert setup for Upstream Bio Inc. performanceJuly 2025 Breakouts & Precise Trade Entry Recommendations - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Is Upstream Bio Inc. stock poised for growth2025 Trade Ideas & Stock Portfolio Risk Management - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Can Upstream Bio Inc. recover in the next quarterPortfolio Update Report & Weekly Setup with High ROI Potential - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Analyzing drawdowns of Upstream Bio Inc. with statistical toolsQuarterly Performance Summary & Verified Stock Trade Ideas - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Developing predictive dashboards with Upstream Bio Inc. dataTrade Entry Summary & Fast Gain Stock Trading Tips - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

How to use Fibonacci retracement on Upstream Bio Inc.Weekly Trend Recap & Free Technical Pattern Based Buy Signals - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Is now a turning point for Upstream Bio Inc.Gold Moves & AI Enhanced Trading Alerts - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Signal strength of Upstream Bio Inc. stock in tech scannersTrade Analysis Summary & Daily Profit Maximizing Tips - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Published on: 2025-09-12 14:03:35 - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

What candlestick patterns are forming on Upstream Bio Inc.2025 Key Lessons & Step-by-Step Trade Execution Guides - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Should you hold or exit Upstream Bio Inc. nowDollar Strength & Stepwise Entry and Exit Trade Signals - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Using portfolio simulators with Upstream Bio Inc. included2025 Performance Recap & Technical Entry and Exit Alerts - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

What moving averages say about Upstream Bio Inc.2025 Pullback Review & Real-Time Stock Price Movement Reports - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Visual trend scoring systems applied to Upstream Bio Inc.July 2025 Outlook & Short-Term High Return Ideas - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Published on: 2025-09-12 04:27:38 - Newser

Sep 12, 2025
pulisher
Sep 12, 2025

Parkman Healthcare Partners LLC Invests $1.43 Million in Upstream Bio, Inc. $UPB - MarketBeat

Sep 12, 2025
pulisher
Sep 12, 2025

Is Upstream Bio Inc. forming a bottoming baseMarket Growth Summary & Capital Protection Trading Alerts - Newser

Sep 12, 2025
pulisher
Sep 11, 2025

Nuveen LLC Takes $138,000 Position in Upstream Bio, Inc. $UPB - MarketBeat

Sep 11, 2025
pulisher
Sep 11, 2025

Is this a good reentry point in Upstream Bio Inc.2025 Volatility Report & Daily Growth Stock Investment Tips - Newser

Sep 11, 2025
pulisher
Sep 11, 2025

Advanced analytics toolkit walkthrough for Upstream Bio Inc.July 2025 Review & Expert Approved Momentum Ideas - Newser

Sep 11, 2025
pulisher
Sep 11, 2025

Published on: 2025-09-11 02:05:45 - Newser

Sep 11, 2025
pulisher
Sep 11, 2025

How to build a dashboard for Upstream Bio Inc. stockTrade Ideas & Scalable Portfolio Growth Methods - Newser

Sep 11, 2025
pulisher
Sep 11, 2025

Detecting support and resistance levels for Upstream Bio Inc.2025 Winners & Losers & Low Risk Entry Point Guides - Newser

Sep 11, 2025
pulisher
Sep 10, 2025

Has Upstream Bio Inc. formed a bullish divergenceMarket Movers & Safe Entry Point Alerts - Newser

Sep 10, 2025
pulisher
Sep 09, 2025

Is Upstream Bio Inc. meeting your algorithmic filter criteriaWeekly Trade Recap & Accurate Trade Setup Notifications - Newser

Sep 09, 2025
pulisher
Sep 09, 2025

Upstream Bio to Participate in the Stifel 2025 Virtual Immunology and Inflammation Forum - markets.businessinsider.com

Sep 09, 2025
pulisher
Sep 09, 2025

Biotech Startup Upstream Bio Takes Stage at Stifel 2025 Virtual Immunology Forum with CEO Fireside Chat - Stock Titan

Sep 09, 2025
pulisher
Sep 09, 2025

Statistical indicators supporting Upstream Bio Inc.’s strengthJuly 2025 Weekly Recap & High Conviction Buy Zone Alerts - Newser

Sep 09, 2025
pulisher
Sep 09, 2025

What MACD and RSI say about Upstream Bio Inc.Market Activity Recap & AI Optimized Trade Strategies - Newser

Sep 09, 2025
pulisher
Sep 09, 2025

Using fundamentals and technicals on Upstream Bio Inc.2025 AllTime Highs & Safe Capital Growth Trade Ideas - Newser

Sep 09, 2025
pulisher
Sep 09, 2025

Long term hold vs stop loss in Upstream Bio Inc.Trade Risk Report & Reliable Entry Point Alerts - Newser

Sep 09, 2025
pulisher
Sep 09, 2025

What to expect from Upstream Bio Inc. in the next 30 daysMarket Weekly Review & Reliable Volume Spike Trade Alerts - Newser

Sep 09, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$36.36
price down icon 0.93%
$83.10
price down icon 3.56%
$27.82
price down icon 2.76%
$96.74
price down icon 7.26%
$145.93
price up icon 0.10%
biotechnology ONC
$324.34
price down icon 3.38%
Cap:     |  Volume (24h):