8.82
price down icon0.23%   -0.02
 
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Upstream Bio Inc stock is traded at $8.82, with a volume of 324.84K. It is down -0.23% in the last 24 hours and up +35.07% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
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Previous Close:
$8.84
Open:
$8.92
24h Volume:
324.84K
Relative Volume:
1.16
Market Cap:
$463.87M
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-6.8654
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
+2.08%
1M Performance:
+35.07%
6M Performance:
-66.31%
1Y Performance:
+0.00%
1-Day Range:
Value
$8.53
$9.40
1-Week Range:
Value
$7.79
$9.40
52-Week Range:
Value
$5.14
$29.46

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

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Biotechnology icon
UPB
Upstream Bio Inc
8.82 463.87M 2.22M -40.51M -46.53M -1.2847
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Vertex Pharmaceuticals Inc
424.99 128.84B 11.10B -988.90M -1.26B -3.92
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REGN
Regeneron Pharmaceuticals Inc
527.78 65.38B 14.09B 4.50B 2.96B 39.28
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ARGX
Argen X Se Adr
549.65 39.67B 2.19B 833.04M -1.28B 12.71
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ALNY
Alnylam Pharmaceuticals Inc
251.15 33.82B 2.35B -269.70M -75.39M -2.09
Biotechnology icon
ONC
Beigene Ltd Adr
231.99 27.60B 3.81B -644.79M -669.77M -6.24

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform

Upstream Bio Inc Stock (UPB) Latest News

pulisher
01:02 AM

Is Upstream Bio Inc (NASDAQ: UPB) A Good Investment Now? - Stocksregister

01:02 AM
pulisher
08:41 AM

Wells Fargo & Company MN Invests $149,000 in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

08:41 AM
pulisher
05:37 AM

27,017 Shares in Upstream Bio, Inc. (NASDAQ:UPB) Acquired by Barclays PLC - Defense World

05:37 AM
pulisher
May 09, 2025

MetLife Investment Management LLC Invests $181,000 in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

May 09, 2025
pulisher
May 09, 2025

Brokers Offer Predictions for Upstream Bio Q2 Earnings - Defense World

May 09, 2025
pulisher
May 07, 2025

Metric Analysis: Upstream Bio Inc (UPB)’s Key Ratios in the Limelight - DWinneX

May 07, 2025
pulisher
May 07, 2025

Upstream Bio Advances Verekitug in Clinical Trials - TipRanks

May 07, 2025
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May 06, 2025

Upstream Bio, Inc.: Strong Buy Rating Driven by Promising Drug Progress and Solid Financial Position - TipRanks

May 06, 2025
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May 06, 2025

Upstream Bio reports Q1 revenue $566k, consensus $326.25k - TipRanks

May 06, 2025
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May 06, 2025

Upstream Bio Reports First Quarter 2025 Financial Results and Accelerates Guidance on All Clinical Programs - GlobeNewswire

May 06, 2025
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May 06, 2025

Transpire Bio Announces R&D and Manufacturing Expansion - The Manila Times

May 06, 2025
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May 05, 2025

Invesco Ltd. Buys Shares of 15,602 Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

May 05, 2025
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May 02, 2025

1,734 Shares in Upstream Bio, Inc. (NASDAQ:UPB) Purchased by Legal & General Group Plc - Defense World

May 02, 2025
pulisher
Apr 29, 2025

JPMorgan Chase & Co. Acquires Shares of 47,792 Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Apr 29, 2025
pulisher
Apr 26, 2025

LPL Financial LLC Cuts Stake in Invesco FTSE RAFI Developed Markets ex-U.S. Small-Mid ETF (NYSEARCA:PDN) - Defense World

Apr 26, 2025
pulisher
Apr 26, 2025

Geode Capital Management LLC Purchases New Position in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Apr 26, 2025
pulisher
Apr 22, 2025

Upstream Bio Inc’s Banking’s 100-Day Moving Average at 11.87: Will the Stock Break Through? - investchronicle.com

Apr 22, 2025
pulisher
Apr 22, 2025

Medical Properties Trust Inc (MPW) Stock: Navigating a Year of Volatility - investchronicle.com

Apr 22, 2025
pulisher
Apr 22, 2025

CytomX Therapeutics Inc’s Shares Reel: -10.73% Quarterly Revenue Decline Amid 60.07M Market Cap - investchronicle.com

Apr 22, 2025
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Apr 22, 2025

Philip Morris International Inc (PM) Stock: Uncovering 52-Week Market Trends - investchronicle.com

Apr 22, 2025
pulisher
Apr 17, 2025

Upstream Bio: Verekitug, A Longer-Acting Dupixent?Key Data Is Imminent - Seeking Alpha

Apr 17, 2025
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Apr 15, 2025

Corebridge Financial Inc. Takes Position in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Apr 15, 2025
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Apr 15, 2025

Amylyx Pharmaceuticals, Inc. (NASDAQ:AMLX) Shares Purchased by American Century Companies Inc. - Defense World

Apr 15, 2025
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Apr 15, 2025

Old Dominion Freight Line (NASDAQ:ODFL) Given New $188.00 Price Target at Stifel Nicolaus - Defense World

Apr 15, 2025
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Apr 14, 2025

Chronic Rhinosinusitis with Nasal Polyps Market to Expand Significantly by 2034, States DelveInsight Report | AstraZeneca, Amgen, Keymed Biosciences, GlaxoSmithKline, Genentech, Inc, Novartis - Barchart.com

Apr 14, 2025
pulisher
Apr 11, 2025

Upstream Bio (NASDAQ:UPB) Is In A Good Position To Deliver On Growth Plans - Yahoo Finance

Apr 11, 2025
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Apr 10, 2025

Amtech Systems, Tesla And Other Big Stocks Moving Lower In Thursday's Pre-Market Session - Benzinga

Apr 10, 2025
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Apr 10, 2025

12 Health Care Stocks Moving In Thursday's Pre-Market Session - Benzinga

Apr 10, 2025
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Apr 10, 2025

Upstream's IPO Lockup Period Expires, RSLS Partners With Israel-based Motion, PVLA On Watch - RTTNews

Apr 10, 2025
pulisher
Apr 10, 2025

Why ReShape Lifesciences Shares Are Trading Higher By Over 82%; Here Are 20 Stocks Moving Premarket - Benzinga

Apr 10, 2025
pulisher
Apr 08, 2025

Certain Common Stock of Upstream Bio, Inc. are subject to a Lock-Up Agreement Ending on 9-APR-2025. - marketscreener.com

Apr 08, 2025
pulisher
Apr 02, 2025

Upstream Bio, Inc.’s Lock-Up Period Will Expire on April 9th (NASDAQ:UPB) - Defense World

Apr 02, 2025
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Mar 29, 2025

Charles Schwab Investment Management Inc. Invests $2.23 Million in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Mar 29, 2025
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Mar 27, 2025

Bank of New York Mellon Corp Invests $607,000 in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Mar 27, 2025
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Mar 25, 2025

Severe Asthma Clinical Trials and Studies 2025: EMA, PDMA, FDA - openPR.com

Mar 25, 2025
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Mar 24, 2025

Upstream Bioprocessing Market Size, Industry Demand And Report Insights By 2033 - Straits Research

Mar 24, 2025
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Mar 20, 2025

1,660 Shares in Upstream Bio, Inc. (NASDAQ:UPB) Acquired by US Bancorp DE - Defense World

Mar 20, 2025
pulisher
Mar 20, 2025

US Bancorp DE Sells 4,285 Shares of SunOpta Inc. (NASDAQ:STKL) - The AM Reporter

Mar 20, 2025
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Mar 19, 2025

Upstream Bio, Inc.: Promising Outlook with Strategic Positioning and Strong Trial Execution - TipRanks

Mar 19, 2025
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Mar 15, 2025

William Blair Lifts Earnings Estimates for Upstream Bio - Defense World

Mar 15, 2025
pulisher
Mar 13, 2025

Long UPB: Upstream Bio’s Robust Financials and Clinical Progress Signal Bullish Reversal - Invezz

Mar 13, 2025
pulisher
Mar 13, 2025

Upstream Bio’s Financial Results and Strategic Progress - TipRanks

Mar 13, 2025
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Mar 12, 2025

Promising Developments and Strong Financial Position Drive Buy Rating for Upstream Bio, Inc. - TipRanks

Mar 12, 2025
pulisher
Mar 12, 2025

Buy Rating for Upstream Bio: Promising Clinical Progress and Unique Drug Candidate Potential - TipRanks

Mar 12, 2025
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Mar 12, 2025

Upstream Bio Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights - The Manila Times

Mar 12, 2025
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Mar 12, 2025

Form 10-K Upstream Bio, Inc. For: Dec 31 - StreetInsider.com

Mar 12, 2025
pulisher
Mar 12, 2025

Upstream Bio, Inc. Completes Enrollment in Phase 2 Trial of Verekitug for Chronic Rhinosinusitis and Raises $293 Million in IPO - Nasdaq

Mar 12, 2025
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Mar 12, 2025

Upstream Bio Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business ... - Enid News & Eagle

Mar 12, 2025
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Mar 10, 2025

Rhumbline Advisers Invests $275,000 in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Mar 10, 2025
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Mar 03, 2025

AstraZeneca And GSK Put Spotlight On Nasal Polyps Space - Citeline News & Insights

Mar 03, 2025
pulisher
Feb 25, 2025

Upstream Bio to Present at Upcoming March Investor Conferences - GlobeNewswire

Feb 25, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Upstream Bio Inc Stock (UPB) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Oct 15 '24
Buy
17.00
825,000
14,025,000
4,554,873
AI Upstream LLC
10% Owner
Oct 15 '24
Buy
17.00
1,175,000
19,975,000
1,175,000
$65.08
price down icon 0.84%
$19.36
price down icon 0.31%
$33.15
price up icon 0.15%
$23.96
price down icon 2.80%
$92.77
price down icon 2.12%
biotechnology ONC
$231.99
price down icon 1.67%
Cap:     |  Volume (24h):