17.63
price down icon0.62%   -0.11
 
loading
Upstream Bio Inc stock is traded at $17.63, with a volume of 289.08K. It is down -0.62% in the last 24 hours and up +64.00% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
See More
Previous Close:
$17.74
Open:
$17.83
24h Volume:
289.08K
Relative Volume:
0.63
Market Cap:
$950.42M
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-13.72
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
-6.87%
1M Performance:
+64.00%
6M Performance:
+120.93%
1Y Performance:
+0.00%
1-Day Range:
Value
$17.54
$18.48
1-Week Range:
Value
$16.02
$19.37
52-Week Range:
Value
$5.14
$29.46

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
UPB
Upstream Bio Inc
17.63 971.45M 2.22M -40.51M -46.53M -1.2847
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
395.12 99.96B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
589.48 60.83B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
454.38 59.89B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
ARGX
Argen X Se Adr
660.00 40.47B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
313.67 37.96B 3.81B -644.79M -669.77M -6.24

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform

Upstream Bio Inc Stock (UPB) Latest News

pulisher
Aug 20, 2025

Can Upstream Bio Inc. Outperform Peers After Recent PullbackQuarterly Earnings Report & Community Consensus Picks - newsyoung.net

Aug 20, 2025
pulisher
Aug 20, 2025

Can trapped investors hope for a rebound in Upstream Bio Inc.2025 Market Sentiment & Short-Term High Return Ideas - Newser

Aug 20, 2025
pulisher
Aug 20, 2025

Analyzing Upstream Bio Inc. with risk reward ratio charts2025 Trading Recap & Consistent Growth Stock Picks - Newser

Aug 20, 2025
pulisher
Aug 20, 2025

Chart based exit strategy for Upstream Bio Inc.Earnings Performance Report & Weekly Stock Performance Updates - Newser

Aug 20, 2025
pulisher
Aug 20, 2025

Upstream Bio Initiates Phase 2 Clinical Trial for COPD Drug, Verekitug - MSN

Aug 20, 2025
pulisher
Aug 19, 2025

Upstream Bio Inc. stock momentum explainedRate Hike & Daily Growth Stock Investment Tips - Newser

Aug 19, 2025
pulisher
Aug 19, 2025

Upstream Bio Inc. Stock Chart Analysis: Bullish or Bearish Pattern FormingAnalyst Upgrade & Daily Oversold Stock Bounce Ideas - Newser

Aug 19, 2025
pulisher
Aug 19, 2025

Analyzing recovery setups for Upstream Bio Inc. investorsJuly 2025 Retail & Daily Chart Pattern Signals - Newser

Aug 19, 2025
pulisher
Aug 19, 2025

What to expect from Upstream Bio Inc. in the next 30 days2025 Momentum Check & Daily Price Action Insights - Newser

Aug 19, 2025
pulisher
Aug 19, 2025

Short interest data insights for Upstream Bio Inc.2025 Technical Patterns & Real-Time Volume Analysis Alerts - Newser

Aug 19, 2025
pulisher
Aug 19, 2025

Upstream Bio Inc. Charts Flash Early Recovery SignalsQuarterly Market Review & Consistent Profit Focused Trading Strategies - 선데이타임즈

Aug 19, 2025
pulisher
Aug 19, 2025

Does Upstream Bio Inc. qualify in momentum factor screeningDividend Hike & AI Forecast for Swing Trade Picks - Newser

Aug 19, 2025
pulisher
Aug 18, 2025

Watch for Trend Continuation in Upstream Bio Inc. Next WeekInflation Watch & Stepwise Swing Trade Plans - newsimpact.co.kr

Aug 18, 2025
pulisher
Aug 18, 2025

How to use a screener to detect Upstream Bio Inc. breakoutsSwing Trade & Long-Term Safe Investment Ideas - Newser

Aug 18, 2025
pulisher
Aug 17, 2025

Key resistance and support levels for Upstream Bio Inc.Entry Point & Expert Curated Trade Setup Alerts - Newser

Aug 17, 2025
pulisher
Aug 17, 2025

Has Upstream Bio Inc. formed a bullish divergenceWeekly Trend Summary & High Return Trade Opportunity Guides - Newser

Aug 17, 2025
pulisher
Aug 17, 2025

Analyzing net buyer seller activity in Upstream Bio Inc.Fed Meeting & Target Return Focused Stock Picks - Newser

Aug 17, 2025
pulisher
Aug 17, 2025

Real time social sentiment graph for Upstream Bio Inc.Market Trend Report & Verified Stock Trade Ideas - Newser

Aug 17, 2025
pulisher
Aug 16, 2025

Upstream Bio (UPB) Q2 R&D Soars 169% - AOL.com

Aug 16, 2025
pulisher
Aug 16, 2025

Building trade automation scripts for Upstream Bio Inc.July 2025 Drop Watch & Free Expert Verified Stock Movement Alerts - Newser

Aug 16, 2025
pulisher
Aug 16, 2025

XTX Topco Ltd Takes $78,000 Position in Upstream Bio, Inc. (NASDAQ:UPB) - Defense World

Aug 16, 2025
pulisher
Aug 16, 2025

Real time breakdown of Upstream Bio Inc. stock performanceTreasury Yields & High Accuracy Trade Signal Alerts - Newser

Aug 16, 2025
pulisher
Aug 15, 2025

Tools to assess Upstream Bio Inc.’s risk profileDollar Strength & Real-Time Volume Surge Alerts - Newser

Aug 15, 2025
pulisher
Aug 14, 2025

Is it too late to sell Upstream Bio Inc.Trade Exit Summary & Safe Entry Zone Identification - Newser

Aug 14, 2025
pulisher
Aug 14, 2025

Can Upstream Bio's (UPB) Rising Losses Outpace Revenue Growth in Its Long-Term Strategy? - simplywall.st

Aug 14, 2025
pulisher
Aug 13, 2025

Ichimoku Cloud Indicates Uncertainty Around Upstream Bio Inc.July 2025 Volume & Reliable Entry Point Alerts - sundaytimes.kr

Aug 13, 2025
pulisher
Aug 12, 2025

Upstream Bio Appoints Stacy Price as Chief Technology Officer - The Globe and Mail

Aug 12, 2025
pulisher
Aug 12, 2025

Upstream Bio Inc. stock retracement – recovery analysisFree Reliable Chart-Based Trade Entries - Newser

Aug 12, 2025
pulisher
Aug 12, 2025

Comparing Upstream Bio Inc. in custom built stock radarsFree Short Term Buy Zone Stock Alerts - Newser

Aug 12, 2025
pulisher
Aug 11, 2025

What makes Upstream Bio Inc. stock price move sharplyForecasting Stock Moves with AI Insights - Newser

Aug 11, 2025
pulisher
Aug 11, 2025

How Efficient Is Upstream Bio Inc. at Controlling Operating CostsChart Signal and Short-Term Forecast Tracker - Newser

Aug 11, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Upstream Bio Inc Stock (UPB) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Oct 15 '24
Buy
17.00
825,000
14,025,000
4,554,873
AI Upstream LLC
10% Owner
Oct 15 '24
Buy
17.00
1,175,000
19,975,000
1,175,000
$24.65
price up icon 0.94%
$85.04
price down icon 1.72%
$26.20
price up icon 0.73%
$110.88
price up icon 0.10%
$131.88
price down icon 0.54%
biotechnology ONC
$313.67
price down icon 0.10%
Cap:     |  Volume (24h):