25.55
price up icon2.36%   0.59
after-market After Hours: 25.55
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Upstream Bio Inc stock is traded at $25.55, with a volume of 384.48K. It is up +2.36% in the last 24 hours and up +14.42% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
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Previous Close:
$24.96
Open:
$24.71
24h Volume:
384.48K
Relative Volume:
0.86
Market Cap:
$1.38B
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-19.89
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
+4.16%
1M Performance:
+14.42%
6M Performance:
+186.11%
1Y Performance:
+43.54%
1-Day Range:
Value
$24.12
$26.10
1-Week Range:
Value
$24.10
$26.20
52-Week Range:
Value
$5.14
$26.90

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
UPB
Upstream Bio Inc
25.55 1.35B 2.22M -40.51M -46.53M -1.2847
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
426.76 107.15B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
755.90 77.46B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
436.38 58.90B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
918.92 56.55B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
198.76 42.58B 447.02M -1.18B -906.14M -6.1812

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-18-25 Initiated Evercore ISI Outperform
Oct-14-25 Initiated Truist Buy
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform
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Upstream Bio Inc Stock (UPB) Latest News

pulisher
Nov 21, 2025

Commit To Buy Upstream Bio At $20, Earn 80.2% Annualized Using Options - Nasdaq

Nov 21, 2025
pulisher
Nov 20, 2025

Why Upstream Bio Inc. stock is popular among millennialsEarnings Trend Report & Free Low Drawdown Momentum Trade Ideas - newser.com

Nov 20, 2025
pulisher
Nov 19, 2025

How strong is Upstream Bio Inc. stock revenue growthEarnings Miss & Stock Portfolio Risk Management - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

What risks investors should watch in Upstream Bio Inc. stock2025 Volatility Report & Growth-Oriented Investment Plans - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Using data filters to optimize entry into Upstream Bio Inc.Earnings Recap Summary & Daily Stock Momentum Reports - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Top investors say Upstream Bio Inc (UPB) ticks everything they need - Setenews

Nov 19, 2025
pulisher
Nov 19, 2025

Upstream Bio (NASDAQ:UPB) Now Covered by Evercore ISI - Defense World

Nov 19, 2025
pulisher
Nov 19, 2025

Upstream Bioprocessing Market on Track for Strong Growth, Estimated to Grow at 12.4% CAGR Through 2029 - openPR.com

Nov 19, 2025
pulisher
Nov 18, 2025

Analyzing Upstream Bio Inc. with multi timeframe chartsTrade Entry Report & Risk Adjusted Swing Trade Ideas - newser.com

Nov 18, 2025
pulisher
Nov 18, 2025

Upstream Bio, Inc.Common Stock (NQ: UPB - FinancialContent

Nov 18, 2025
pulisher
Nov 18, 2025

Evercore ISI Group Initiates Coverage of Upstream Bio (UPB) with Outperform Recommendation - Nasdaq

Nov 18, 2025
pulisher
Nov 18, 2025

Upstream Bio initiated with an Outperform at Evercore ISI - MSN

Nov 18, 2025
pulisher
Nov 18, 2025

Upstream Bio, Inc.’s Verekitug: A Promising Buy with Blockbuster Potential in Asthma and COPD Markets - TipRanks

Nov 18, 2025
pulisher
Nov 18, 2025

Why hedge funds are buying Upstream Bio Inc. stockTrade Analysis Summary & Verified Entry Point Detection - newser.com

Nov 18, 2025
pulisher
Nov 16, 2025

What earnings revisions data tells us about Upstream Bio Inc.2025 Price Momentum & Community Driven Trade Alerts - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Ranking Upstream Bio Inc. among high performing stocks via toolsJuly 2025 Rallies & Daily Price Action Insights - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Can momentum traders help lift Upstream Bio Inc.Earnings Risk Summary & Smart Investment Allocation Insights - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Is Upstream Bio Inc. stock trading at a premium valuationEarnings Risk Summary & Smart Swing Trading Alerts - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Can Upstream Bio Inc. stock resist sector downturnsShort Setup & Real-Time Volume Triggers - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Candlestick signals on Upstream Bio Inc. stock todayPortfolio Gains Summary & Fast Exit Strategy with Risk Control - newser.com

Nov 16, 2025
pulisher
Nov 15, 2025

Is Upstream Bio Inc. stock dividend yield sustainable2025 Breakouts & Breakdowns & AI Forecast for Swing Trade Picks - newser.com

Nov 15, 2025
pulisher
Nov 14, 2025

Upstream Bio Reports Progress in Respiratory Trials - MSN

Nov 14, 2025
pulisher
Nov 14, 2025

Custom watchlist performance reports with Upstream Bio Inc.July 2025 Fed Impact & Real-Time Market Trend Scan - newser.com

Nov 14, 2025
pulisher
Nov 14, 2025

What dividend safety score for Upstream Bio Inc. stockIndex Update & Reliable Price Breakout Alerts - newser.com

Nov 14, 2025
pulisher
Nov 13, 2025

Upstream Bio Inc Stock Analysis and ForecastBearish Engulfing Patterns & Achieve Consistent Profits - earlytimes.in

Nov 13, 2025
pulisher
Nov 12, 2025

Can Upstream Bio Inc. stock sustain revenue growthQuarterly Portfolio Report & Long-Term Capital Growth Strategies - newser.com

Nov 12, 2025
pulisher
Nov 12, 2025

Will Upstream Bio Inc. stock outperform growth indexesJuly 2025 Momentum & Weekly Breakout Stock Alerts - newser.com

Nov 12, 2025
pulisher
Nov 12, 2025

3 Best Biotech Stocks to Buy Now, 11/12/2025, According to Top Analysts - TipRanks

Nov 12, 2025
pulisher
Nov 10, 2025

Can Upstream Bio Inc. stock deliver surprise earnings beatTrade Volume Report & Risk Controlled Stock Pick Alerts - newser.com

Nov 10, 2025
pulisher
Nov 09, 2025

Why Upstream Bio Inc. stock remains undervaluedMarket Performance Recap & Growth Focused Stock Pick Reports - newser.com

Nov 09, 2025
pulisher
Nov 08, 2025

Published on: 2025-11-08 03:19:27 - newser.com

Nov 08, 2025
pulisher
Nov 08, 2025

Q3 EPS Estimates for Upstream Bio Lifted by William Blair - Defense World

Nov 08, 2025
pulisher
Nov 07, 2025

Upstream Bio Inc Files for Mixed Shelf ; Size Not DisclosedSEC Filing - 富途牛牛

Nov 07, 2025
pulisher
Nov 07, 2025

How resilient is Upstream Bio Inc. stock in market downturnsJuly 2025 Update & Safe Capital Allocation Plans - newser.com

Nov 07, 2025
pulisher
Nov 06, 2025

Will Upstream Bio Inc. stock recover faster than peersJuly 2025 Movers & Weekly High Return Forecasts - Fundação Cultural do Pará

Nov 06, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$38.92
price up icon 1.38%
$30.45
price up icon 1.36%
$102.06
price up icon 0.29%
$95.59
price down icon 1.42%
biotechnology ONC
$347.72
price down icon 0.45%
$198.76
price down icon 0.44%
Cap:     |  Volume (24h):