21.47
price up icon3.57%   0.74
after-market After Hours: 21.77 0.30 +1.40%
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Apellis Pharmaceuticals Inc stock is traded at $21.47, with a volume of 6.49M. It is up +3.57% in the last 24 hours and down -5.13% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade.
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Previous Close:
$20.73
Open:
$21
24h Volume:
6.49M
Relative Volume:
2.53
Market Cap:
$2.71B
Revenue:
$715.22M
Net Income/Loss:
$-250.10M
P/E Ratio:
-10.58
EPS:
-2.03
Net Cash Flow:
$-205.58M
1W Performance:
-23.78%
1M Performance:
-5.13%
6M Performance:
+11.76%
1Y Performance:
-21.24%
1-Day Range:
Value
$19.25
$21.80
1-Week Range:
Value
$19.25
$30.48
52-Week Range:
Value
$16.10
$35.72

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
710
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
APLS
Apellis Pharmaceuticals Inc
21.47 2.62B 715.22M -250.10M -205.58M -2.03
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
425.57 107.66B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
651.80 68.74B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
456.04 58.93B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
818.50 50.51B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
189.60 41.29B 447.02M -1.18B -868.57M -6.1812

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
Nov 02, 2025

Regression analysis insights on Apellis Pharmaceuticals Inc. performanceQuarterly Profit Review & Daily Growth Stock Investment Tips - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will breakout in Apellis Pharmaceuticals Inc. lead to full recovery2025 Risk Factors & Expert Approved Momentum Ideas - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

How to build a dashboard for Apellis Pharmaceuticals Inc. stockFed Meeting & Reliable Price Breakout Signals - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Does Apellis Pharmaceuticals Inc. (1JK) stock trade below intrinsic value2025 Price Targets & High Return Stock Watch Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will Apellis Pharmaceuticals Inc. (1JK) stock rise with strong economy2025 Institutional Moves & Safe Swing Trade Setup Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Apellis Pharmaceuticals Hits Day Low of $20.66 Amid Price Pressure - Markets Mojo

Nov 02, 2025
pulisher
Nov 02, 2025

Brighton Jones LLC Buys Shares of 16,539 Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Apellis Pharmaceuticals Inc. recovery potential after sell off2025 Market WrapUp & Verified Momentum Stock Watchlist - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Apellis Pharmaceuticals Inc. stock prediction for this weekWeekly Trend Recap & Smart Money Movement Tracker - newser.com

Nov 02, 2025
pulisher
Nov 01, 2025

Why retail investors favor Apellis Pharmaceuticals Inc. stockJuly 2025 Closing Moves & Weekly Setup with ROI Potential - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Citigroup Issues Pessimistic Forecast for Apellis Pharmaceuticals (NASDAQ:APLS) Stock Price - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Price Target Lowered to $45.00 at TD Cowen - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Is Apellis Pharmaceuticals Inc. stock attractive for income investorsMarket Trend Review & Free Real-Time Volume Trigger Notifications - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Price Target Cut to $45.00 by Analysts at HC Wainwright - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Robert W. Baird Issues Positive Forecast for Apellis Pharmaceuticals (NASDAQ:APLS) Stock Price - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Q3 2025 Earnings Call Transcript - Insider Monkey

Nov 01, 2025
pulisher
Nov 01, 2025

How sentiment analysis helps forecast Apellis Pharmaceuticals Inc.July 2025 Movers & Weekly High Return Opportunities - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Jennison Associates LLC Raises Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Y Intercept Hong Kong Ltd Has $2.84 Million Stock Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

Will Apellis Pharmaceuticals Inc. stock maintain dividend yieldShort Setup & Smart Swing Trading Alerts - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Apellis Pharmaceuticals, Inc. $APLS Shares Sold by AlphaQuest LLC - MarketBeat

Nov 01, 2025
pulisher
Nov 01, 2025

How Apellis Pharmaceuticals Inc. stock performs in weak economyJuly 2025 Breakouts & Verified Chart Pattern Signals - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Real time scanner hits for Apellis Pharmaceuticals Inc. explainedPrice Action & Fast Gaining Stock Reports - newser.com

Nov 01, 2025
pulisher
Oct 31, 2025

APLS: Citigroup Lowers Price Target Amidst Maintained Buy Rating - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Shares Gap DownTime to Sell? - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals Inc Stock Analysis and ForecastDividend Cut Warnings & Free Wealth Planning Blueprints - earlytimes.in

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Stock Down Despite Q3 Earnings and Revenues Beat Estimates - sharewise.com

Oct 31, 2025
pulisher
Oct 31, 2025

APLS Analyst Rating Update: TD Cowen Adjusts Price Target | APLS Stock News - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Releases Quarterly Earnings Results, Beats Estimates By $0.64 EPS - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals, Inc. 2025 Q3ResultsEarnings Call Presentation (NASDAQ:APLS) 2025-10-31 - Seeking Alpha

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals (APLS): Forecast 13% Annual Revenue Growth, Shares Trade at Deep Discount Heading Into Earnings - Yahoo Finance

Oct 31, 2025
pulisher
Oct 31, 2025

APLS Stock: Baird Raises Price Target to $52, Maintains Outperfo - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

APLS: HC Wainwright & Co. Lowers Price Target, Maintains 'Buy' Rating | APLS Stock News - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

What valuation ratios show for Apellis Pharmaceuticals Inc. (1JK) stockTrade Risk Assessment & Low Volatility Stock Recommendations - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

How moving averages guide Apellis Pharmaceuticals Inc. tradingMarket Sentiment Review & Free High Return Stock Watch Alerts - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Apellis Pharmaceuticals Reports Strong Q3 2025 Earnings - TipRanks

Oct 31, 2025
pulisher
Oct 31, 2025

Can Apellis Pharmaceuticals Inc. stock sustain market leadership2025 Pullback Review & Free Growth Oriented Trading Recommendations - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Decoding Apellis Pharmaceuticals Inc (APLS): A Strategic SWOT In - GuruFocus

Oct 31, 2025
pulisher
Oct 31, 2025

What high frequency data says about Apellis Pharmaceuticals Inc.2025 Market Sentiment & Free Community Consensus Stock Picks - newser.com

Oct 31, 2025
pulisher
Oct 30, 2025

Apellis Pharmaceuticals Q3 2025 Earnings Call Transcript - MarketBeat

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis Pharmaceuticals Inc (APLS) Q3 2025 Earnings Call Highlights: Strong Revenue Growth and ... By GuruFocus - Investing.com Canada

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis Pharmaceuticals Inc (APLS) Q3 2025 Earnings Call Highlights: Strong Revenue Growth and ... - Yahoo Finance

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis down as Goldman Sachs cuts to sell on risks to outlook - MSN

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis Pharma earnings beat by $0.12, revenue topped estimates - Investing.com Canada

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis’ $458M Shocker: FDA Win, Analyst Buzz & 20% Stock Whiplash - ts2.tech

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis (APLS) Shares Decline by Nearly 25% - GuruFocus

Oct 30, 2025
pulisher
Oct 30, 2025

CapEx per share of Apellis Pharmaceuticals, Inc. – MUN:1JK - TradingView

Oct 30, 2025
pulisher
Oct 30, 2025

Earnings call transcript: Apellis Pharmaceuticals Q3 2025 earnings beat expectations but stock tumbles - Investing.com Nigeria

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis (APLS) Shares Drop Sharply by Over 19% - GuruFocus

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis Gets A Rare Edge With Big Sobi Payout And Strong Drug Sales - Finimize

Oct 30, 2025
pulisher
Oct 30, 2025

Apellis Pharmaceuticals Inc reports results for the quarter ended September 30Earnings Summary - TradingView

Oct 30, 2025

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$37.54
price up icon 1.62%
$93.48
price up icon 0.96%
$28.61
price down icon 0.21%
$103.91
price down icon 0.73%
biotechnology ONC
$310.48
price up icon 0.73%
$189.60
price down icon 2.38%
Cap:     |  Volume (24h):