4.21
price down icon4.10%   -0.18
after-market After Hours: 4.28 0.07 +1.66%
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Aptevo Therapeutics Inc stock is traded at $4.21, with a volume of 37,978. It is down -4.10% in the last 24 hours and down -7.47% over the past month. Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTIR and ADAPTIR-FLEX platforms are designed to generate monospecific, bispecific, and multi-specific antibody candidates that are capable of enhancing the human immune system against cancer cells.
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Previous Close:
$4.39
Open:
$4.38
24h Volume:
37,978
Relative Volume:
0.72
Market Cap:
$5.25M
Revenue:
$12.99M
Net Income/Loss:
$-27.83M
P/E Ratio:
-0.0207
EPS:
-203.7366
Net Cash Flow:
$-26.98M
1W Performance:
-11.46%
1M Performance:
-7.47%
6M Performance:
-49.03%
1Y Performance:
-92.36%
1-Day Range:
Value
$4.1684
$4.45
1-Week Range:
Value
$4.1684
$4.61
52-Week Range:
Value
$3.6803
$55.26

Aptevo Therapeutics Inc Stock (APVO) Company Profile

Name
Name
Aptevo Therapeutics Inc
Name
Phone
206-838-0500
Name
Address
2401 4TH AVE., SEATTLE, WA
Name
Employee
33
Name
Twitter
@aptevo
Name
Next Earnings Date
2026-08-10
Name
Latest SEC Filings
Name
APVO's Discussions on Twitter

Compare APVO vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
APVO icon
APVO
Aptevo Therapeutics Inc
4.21 5.47M 12.99M -27.83M -26.98M -203.74
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
479.00 121.16B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
667.17 68.78B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
888.82 57.44B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
188.07 40.23B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
278.40 36.28B 4.29B 577.22M 641.34M 4.2086

Aptevo Therapeutics Inc Stock (APVO) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-18 Initiated Ladenburg Thalmann Buy
Oct-05-17 Resumed Piper Jaffray Overweight

Aptevo Therapeutics Inc Stock (APVO) Latest News

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Jul 27, 2026

Aptevo Therapeutics Unveils New Solid Tumor Strategy - TipRanks

Jul 27, 2026
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Jul 27, 2026

Aptevo files patent for Nectin-4 x PD-L1 cancer platform - Investing.com

Jul 27, 2026
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Jul 27, 2026

Aptevo Filing May Support Radiopharmaceuticals and T-Cell Engagers - Stock Titan

Jul 27, 2026
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Jul 27, 2026

Aptevo Therapeutics Inc (APVO) Cash Flow - TradingKey

Jul 27, 2026
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Jul 27, 2026

Aptevo Therapeutics Inc (APVO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 27, 2026
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Jul 27, 2026

Aptevo Therapeutics Inc (APVO) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jul 27, 2026
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Jul 27, 2026

APVO|Aptevo Therapeutics Inc|Price:4.390|Chg%:+0.020 - TradingKey

Jul 27, 2026
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Jul 25, 2026

TradingKey - TradingKey

Jul 25, 2026
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Jul 25, 2026

Aptevo Therapeutics Inc. Revenue Breakdown – NASDAQ:APVO - TradingView

Jul 25, 2026
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Jul 24, 2026

Aptevo Therapeutics Inc (APVO) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jul 24, 2026
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Jul 16, 2026

Mary Jo Janatpour Net Worth (2026) - GuruFocus

Jul 16, 2026
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Jul 16, 2026

Niowave, Inc. Net Worth (2026) - GuruFocus

Jul 16, 2026
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Jul 07, 2026

Aptevo Therapeutics Inc (APVO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jul 07, 2026
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Jul 05, 2026

Aptevo Therapeutics (APVO) Edges Higher: Testing Key Resistance Amid Steady VolumeBPI Reversal - dars.gov.et

Jul 05, 2026
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Jul 01, 2026

Aptevo Therapeutics Secures Grant for APVO451 Development - The Globe and Mail

Jul 01, 2026
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Jul 01, 2026

Grant supports Aptevo’s immunotherapy APVO-451 for solid tumors - BioWorld News

Jul 01, 2026
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Jun 30, 2026

Aptevo (NASDAQ: APVO) gets $1.5M CARE Fund grant to advance APVO451 - Stock Titan

Jun 30, 2026
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Jun 30, 2026

Aptevo receives $1.5M grant for cancer therapy development - Investing.com

Jun 30, 2026
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Jun 30, 2026

Aptevo Secures $1.5 Million Non-Dilutive Research Grant From the Andy Hill Care Fund to Advance APVO451, a Nectin-4-Targeted Trispecific Immunotherapy for Solid Tumors - The Joplin Globe

Jun 30, 2026
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Jun 30, 2026

Aptevo gets $1.5M grant to advance a trispecific cancer drug - Stock Titan

Jun 30, 2026
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Jun 28, 2026

Price to sales forward of Aptevo Therapeutics Inc. – NASDAQ:APVO - TradingView

Jun 28, 2026
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Jun 28, 2026

Price to sales forward of Aptevo Therapeutics, Inc. – MUN:AP82 - TradingView

Jun 28, 2026
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Jun 28, 2026

Aptevo Therapeutics (APVO) Edges Lower, Testing Key Support LevelsFlat Correction - dars.gov.et

Jun 28, 2026
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Jun 27, 2026

Price to book forward of Aptevo Therapeutics Inc. – NASDAQ:APVO - TradingView

Jun 27, 2026
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Jun 27, 2026

APVO Forecast — Price Target — Prediction for 2027 - TradingView

Jun 27, 2026
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Jun 27, 2026

Price to earnings forward of Aptevo Therapeutics Inc. – NASDAQ:APVO - TradingView

Jun 27, 2026
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Jun 27, 2026

Enterprise value to EBIT forward of Aptevo Therapeutics Inc. – NASDAQ:APVO - TradingView

Jun 27, 2026
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Jun 27, 2026

Price to earnings forward of Aptevo Therapeutics, Inc. – MUN:AP82 - TradingView

Jun 27, 2026
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Jun 26, 2026

Aptevo Therapeutics, Inc. Actuals & Estimates (NASDAQ:APVO) - TradingView

Jun 26, 2026
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Jun 26, 2026

Aptevo Therapeutics, Inc. Actuals & Estimates (MUN:AP82) - TradingView

Jun 26, 2026
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Jun 26, 2026

Aptevo Therapeutics (APVO) Gains 2.73% as Shares Test Key Resistance Near $4.95ETF Creation Redemption - dars.gov.et

Jun 26, 2026
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Jun 25, 2026

Aptevo Therapeutics, Inc. Actuals & Estimates (FWB:AP82) - TradingView

Jun 25, 2026
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Jun 25, 2026

AP82 Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
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Jun 23, 2026

Aptevo Therapeutics Inc (APVO) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 23, 2026
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Jun 22, 2026

Form 13G Aptevo Therapeutics Inc. For: 22 June By Investing.com - Investing.com South Africa

Jun 22, 2026
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Jun 22, 2026

Niowave holds 12.18% of Aptevo (NASDAQ: APVO) — 151,723 shares - Stock Titan

Jun 22, 2026
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Jun 22, 2026

NIOWAVE, INC. (NASDAQ: APVO) discloses 98,522 shares and $8 warrants - Stock Titan

Jun 22, 2026
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Jun 18, 2026

Aptevo Therapeutics Inc (APVO) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 18, 2026
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Jun 18, 2026

Aptevo Therapeutics Inc (APVO) Institutional Confidence - TradingKey

Jun 18, 2026
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Jun 17, 2026

Aptevo Therapeutics Inc (APVO) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Aptevo Therapeutics Inc (APVO) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 17, 2026
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Jun 09, 2026

Aptevo and Niowave Partner to Advance Radiopharmaceutical Cancer Therapies - citybuzz -

Jun 09, 2026
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Jun 09, 2026

As Big Pharma Bets On Radiopharmaceuticals, Aptevo And Niowave Join Forces To Advance Novel Targeted Cancer Therapeutics In The $17B+ Oncology Category - NewMediaWire

Jun 09, 2026
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Jun 05, 2026

Aptevo reports 87% clinical benefit rate in AML trial - Investing.com

Jun 05, 2026
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May 31, 2026

- The Legal Advocate

May 31, 2026
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May 31, 2026

Aptevo Therapeutics (APVO) Slips 1.43% as Shares Approach Support at $4.66Volume Climax - dars.gov.et

May 31, 2026
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May 30, 2026

Aptevo Therapeutics (APVO) Slips 1.43% as Shares Test Key Support Near $4.66Butterfly Setup - The Legal Advocate

May 30, 2026
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May 30, 2026

Aptevo Therapeutics (APVO) Holds Near Support After Modest DeclineHedge Fund Favorites - dars.gov.et

May 30, 2026
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May 29, 2026

Aptevo Therapeutics Dip Continues as Stock Consolidates Near Key SupportBuffered ETF - The Legal Advocate

May 29, 2026
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May 29, 2026

Aptevo Therapeutics (APVO) Slides Lower as Support Level Comes Into FocusFibonacci Retracement - The Legal Advocate

May 29, 2026
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May 28, 2026

Aptevo Therapeutics (APVO) SVP, CSO files Form 3 reporting zero shares - Stock Titan

May 28, 2026

Aptevo Therapeutics Inc Stock (APVO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$91.09
price up icon 1.97%
$118.87
price up icon 1.02%
$34.72
price down icon 0.83%
$58.73
price down icon 0.17%
ONC ONC
$325.90
price up icon 0.00%
$278.40
price up icon 2.44%
Cap:     |  Volume (24h):