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Karyopharm Therapeutics Inc stock is traded at $6.30, with a volume of 112.18K. It is up +4.65% in the last 24 hours and up +61.95% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$6.02
Open:
$6.03
24h Volume:
112.18K
Relative Volume:
0.77
Market Cap:
$54.63M
Revenue:
$137.27M
Net Income/Loss:
$-123.57M
P/E Ratio:
-0.5753
EPS:
-10.95
Net Cash Flow:
$-102.89M
1W Performance:
+6.42%
1M Performance:
+61.95%
6M Performance:
-29.81%
1Y Performance:
-46.65%
1-Day Range:
Value
$6.03
$6.5199
1-Week Range:
Value
$5.49
$7.01
52-Week Range:
Value
$3.51
$16.95

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
KPTI
Karyopharm Therapeutics Inc
6.30 48.47M 137.27M -123.57M -102.89M -10.95
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VRTX
Vertex Pharmaceuticals Inc
395.12 99.96B 11.39B 3.64B 3.50B 13.99
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REGN
Regeneron Pharmaceuticals Inc
589.48 60.83B 14.21B 4.46B 3.56B 39.68
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ALNY
Alnylam Pharmaceuticals Inc
454.38 59.89B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
ARGX
Argen X Se Adr
660.00 40.47B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
313.67 37.96B 3.81B -644.79M -669.77M -6.24

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Jul-16-25 Downgrade H.C. Wainwright Buy → Neutral
Jul-11-25 Resumed H.C. Wainwright Buy
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
Aug 20, 2025

AI Indicators Detect Buy Opportunity in Karyopharm Therapeutics Inc.July 2025 Action & Daily Stock Trend Watchlist - beatles.ru

Aug 20, 2025
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Aug 18, 2025

Karyopharm’s Earnings Call: Clinical Wins Amid Financial Strain - MSN

Aug 18, 2025
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Aug 17, 2025

Will Karyopharm Therapeutics Inc. benefit from rate cutsJuly 2025 Fed Impact & Growth Oriented Trade Recommendations - classian.co.kr

Aug 17, 2025
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Aug 16, 2025

What are Karyopharm Therapeutics Inc.’s recent SEC filings showingMarket Risk Report & Reliable Entry Point Alerts - thegnnews.com

Aug 16, 2025
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Aug 16, 2025

Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) Shares Bounce 42% But Its Business Still Trails The Industry - 富途牛牛

Aug 16, 2025
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Aug 16, 2025

Can Karyopharm Therapeutics Inc. rally from current levelsWeekly Profit Analysis & Technical Pattern Recognition Alerts - Newser

Aug 16, 2025
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Aug 16, 2025

Karyopharm Therapeutics Inc. stock prediction for this weekTrade Volume Report & Free Weekly Chart Analysis and Trade Guides - Newser

Aug 16, 2025
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Aug 16, 2025

Advanced analytics toolkit walkthrough for Karyopharm Therapeutics Inc.Portfolio Profit Report & Verified Momentum Stock Alerts - Newser

Aug 16, 2025
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Aug 16, 2025

How to read the order book for Karyopharm Therapeutics Inc.July 2025 Drop Watch & Capital Protection Trading Alerts - Newser

Aug 16, 2025
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Aug 16, 2025

Published on: 2025-08-16 03:21:01 - Newser

Aug 16, 2025
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Aug 16, 2025

Comparing Karyopharm Therapeutics Inc. in custom built stock radarsWeekly Market Report & Safe Capital Preservation Plans - Newser

Aug 16, 2025
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Aug 15, 2025

How moving averages guide Karyopharm Therapeutics Inc. tradingPortfolio Gains Summary & Free Community Supported Trade Ideas - Newser

Aug 15, 2025
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Aug 15, 2025

Will Karyopharm Therapeutics Inc. Benefit From Broader Market BounceJuly 2025 Retail & Pattern Based Trade Signal System - beatles.ru

Aug 15, 2025
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Aug 15, 2025

Is a relief rally coming for Karyopharm Therapeutics Inc. holders2025 Support & Resistance & Risk Controlled Swing Alerts - Newser

Aug 15, 2025
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Aug 15, 2025

What makes Karyopharm Therapeutics Inc. stock attractive to long term investorsM&A Rumor & Safe Investment Capital Preservation Plans - Newser

Aug 15, 2025
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Aug 15, 2025

Karyopharm's 24.5% Intraday Surge: A High-Stakes Gamble Between Cash Runway and Clinical Catalysts - AInvest

Aug 15, 2025
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Aug 15, 2025

Cautious Hold on Karyopharm Therapeutics Amid Revenue Guidance Cut and Clinical Delays - TipRanks

Aug 15, 2025
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Aug 15, 2025

Layoff Tracker: Bausch Health Closes California Site, Cuts 49 Employees - BioSpace

Aug 15, 2025
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Aug 15, 2025

Why Karyopharm Therapeutics Inc. stock attracts strong analyst attention2025 Bull vs Bear & AI Powered Market Trend Analysis - Newser

Aug 15, 2025
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Aug 14, 2025

US$25.92: That's What Analysts Think Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Is Worth After Its Latest Results - simplywall.st

Aug 14, 2025
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Aug 13, 2025

Karyopharm Therapeutics’ SWOT analysis: biotech firm’s stock faces pivotal year - Investing.com

Aug 13, 2025
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Aug 13, 2025

Karyopharm Therapeutics (KPTI) Reports Q2 Loss, Lags Revenue Estimates - MSN

Aug 13, 2025
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Aug 13, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Q2 2025 Earnings Call Transcript - Insider Monkey

Aug 13, 2025
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Aug 13, 2025

Karyopharm Therapeutics (NASDAQ:KPTI) Given New $25.00 Price Target at Robert W. Baird - Defense World

Aug 13, 2025
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Aug 12, 2025

Karyopharm Therapeutics shares rise 1.03% premarket after reporting Q2 earnings. - AInvest

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics Inc. Builds Base for Possible ReboundOversold Bounce Stock Play Ideas Gain Attention - beatles.ru

Aug 12, 2025
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Aug 12, 2025

Baird Lowers Karyopharm PT to $25 from $42 Amid Patent Concerns - AInvest

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics Reports Q2 Loss Amid Revenue ShortfallNews and Statistics - IndexBox

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics: Q2 Earnings Snapshot - Connecticut Post

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics Inc (KPTI) Q2 2025 Earnings Call Highlights: Navigating Financial ... - Yahoo Finance

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics Inc (KPTI) Q2 2025 Earnings Call Highlights: Navigating Financial ... By GuruFocus - Investing.com Canada

Aug 12, 2025
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Aug 12, 2025

Will Karyopharm Therapeutics Inc. see short term momentumFree Momentum Based Equity Trading Plan - Newser

Aug 12, 2025
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Aug 12, 2025

Karyopharm Therapeutics Reports Q2 2025 Earnings - TipRanks

Aug 12, 2025
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Aug 11, 2025

Karyopharm’s Revenue Dips As Drug Sales Inch Upward - Finimize

Aug 11, 2025
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Aug 11, 2025

Karyopharm Sees Mixed Q2 As XPOVIO Sales Climb - Finimize

Aug 11, 2025
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Aug 11, 2025

Karyopharm outlines $1B peak U.S. revenue opportunity in myelofibrosis with pivotal Phase III data expected by March 2026 - MSN

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Sees $1B Peak Revenue Potential in Myelofibrosis by 2026 - AInvest

Aug 11, 2025
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Aug 11, 2025

Karyopharm Reports Q2 2025 Financial Results, Updates Guidance, and Explores Financing and Strategic Alternatives - AInvest

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Inc. 2025 Q2ResultsEarnings Call Presentation (NASDAQ:KPTI) - Seeking Alpha

Aug 11, 2025
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Aug 11, 2025

Earnings call transcript: Karyopharm Q2 2025 sees revenue decline amid strategic shifts - Investing.com Nigeria

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Inc reports results for the quarter ended June 30Earnings Summary - TradingView

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Q2 2025 Earnings Call Transcript - MarketBeat

Aug 11, 2025
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Aug 11, 2025

Transcript : Karyopharm Therapeutics Inc., Q2 2025 Earnings Call, Aug 11, 2025 - MarketScreener

Aug 11, 2025
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Aug 11, 2025

Karyopharm Reports Second Quarter 2025 Financial Results and Highlights Recent Company Progress - Citizen Tribune

Aug 11, 2025
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Aug 11, 2025

Karyopharm Q2 2025 slides: Myelofibrosis pivot amid mixed financial results By Investing.com - Investing.com South Africa

Aug 11, 2025
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Aug 11, 2025

Karyopharm Q2 2025 slides: Myelofibrosis pivot amid mixed financial results - Investing.com

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Q2 revenue falls 11% - MarketScreener

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Inc. SEC 10-Q Report - TradingView

Aug 11, 2025
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Aug 11, 2025

Karyopharm Therapeutics Q2 EPS Misses Estimate, Revenue Down 11.4% Y/Y - AInvest

Aug 11, 2025
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Aug 11, 2025

Karyopharm Q2 rev. $37.9mln, up 6% YoY; updates FY guidance. - AInvest

Aug 11, 2025
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Aug 11, 2025

Multi Factor Analysis Ranks Karyopharm Therapeutics Inc. as Strong BuyMomentum Based Equity Trading Plans Reviewed - beatles.ru

Aug 11, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Karyopharm Therapeutics Inc Stock (KPTI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Abate Kristin
Chief Accounting Officer
Jul 22 '25
Sale
4.00
238
952
9,475
Paulson Richard A.
President and CEO
May 06 '25
Sale
7.12
236
1,680
82,503
Rangwala Reshma
EVP & Chief Medical Officer
Apr 23 '25
Sale
6.17
419
2,585
28,853
Paulson Richard A.
President and CEO
Apr 04 '25
Sale
3.74
245
916
82,739
Cheng Sohanya Roshan
EVP & Chief Commercial Officer
Mar 04 '25
Sale
6.29
3,445
21,669
34,314
Paulson Richard A.
President and CEO
Mar 04 '25
Sale
6.29
11,694
73,555
82,984
Rangwala Reshma
EVP & Chief Medical Officer
Mar 04 '25
Sale
6.29
3,587
22,562
29,272
Poulton Stuart
EVP, Chief Development Officer
Mar 04 '25
Sale
6.29
3,548
22,317
27,414
Mano Michael
SVP, General Counsel&Secretary
Mar 04 '25
Sale
6.29
2,793
17,568
21,047
Poulton Stuart
EVP, Chief Development Officer
Feb 18 '25
Sale
0.63
5,914
3,726
320,714
$24.65
price up icon 0.94%
$85.04
price down icon 1.72%
$26.20
price up icon 0.73%
$110.88
price up icon 0.10%
$131.88
price down icon 0.54%
biotechnology ONC
$313.67
price down icon 0.10%
Cap:     |  Volume (24h):