4.20
price down icon7.28%   -0.33
after-market After Hours: 4.20
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Karyopharm Therapeutics Inc stock is traded at $4.20, with a volume of 109.89K. It is down -7.28% in the last 24 hours and down -37.78% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$4.53
Open:
$4.48
24h Volume:
109.89K
Relative Volume:
0.89
Market Cap:
$36.29M
Revenue:
$140.46M
Net Income/Loss:
$-146.34M
P/E Ratio:
-3.3071
EPS:
-1.27
Net Cash Flow:
$-117.73M
1W Performance:
-8.50%
1M Performance:
-37.78%
6M Performance:
-66.87%
1Y Performance:
-70.47%
1-Day Range:
Value
$4.15
$4.6468
1-Week Range:
Value
$4.15
$4.8132
52-Week Range:
Value
$3.51
$17.40

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

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Biotechnology icon
KPTI
Karyopharm Therapeutics Inc
4.20 40.09M 140.46M -146.34M -117.73M -1.27
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ONC
Beone Medicines Ltd Adr
245.58 25.81B 3.81B -644.79M -669.77M -6.24
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VRTX
Vertex Pharmaceuticals Inc
441.85 111.46B 11.10B -988.90M -1.26B -3.92
Biotechnology icon
AKTX
Akari Therapeutics Plc Adr
1.35 40.37M 0 0 0 0.00
Biotechnology icon
VRNA
Verona Pharma Plc Adr
81.16 6.19B 0 -153.72M -103.81M -2.00
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
489.52 64.44B 14.09B 4.50B 2.96B 39.28

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
03:25 AM

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Shares Acquired by Jane Street Group LLC - Defense World

03:25 AM
pulisher
May 29, 2025

Karyopharm increases share reserve for equity plan By Investing.com - Investing.com India

May 29, 2025
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May 29, 2025

Karyopharm Therapeutics Stockholders Approve Equity Plan Amendment - TipRanks

May 29, 2025
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May 29, 2025

Karyopharm increases share reserve for equity plan - Investing.com

May 29, 2025
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May 29, 2025

D. E. Shaw & Co. Inc. Sells 817,711 Shares of Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

May 29, 2025
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May 28, 2025

Hepatic Impairment Market Predicted to See Upsurge Through 2032, Highlights DelveInsight | Novartis, ApoPharma, Indivior Inc., Boehringer Ingelheim, Ocera Therapeutics, Orient Europharma, Karyopharm - Barchart.com

May 28, 2025
pulisher
May 27, 2025

Focus Partners Wealth Makes New Investment in Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

May 27, 2025
pulisher
May 26, 2025

Here's Why Karyopharm Therapeutics (KPTI) Is a Great 'Buy the Bottom' Stock Now - Yahoo Finance

May 26, 2025
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May 25, 2025

Karyopharm Therapeutics’ SWOT analysis: oncology firm’s stock faces pivotal year - Investing.com Nigeria

May 25, 2025
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May 24, 2025

Investors Don't See Light At End Of Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) Tunnel And Push Stock Down 27% - simplywall.st

May 24, 2025
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May 22, 2025

Here's Why Shareholders May Want To Be Cautious With Increasing Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) CEO Pay Packet - simplywall.st

May 22, 2025
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May 21, 2025

Karyopharm at RBC Capital Markets: Strategic Insights on XPOVIO and Pipeline - Investing.com Australia

May 21, 2025
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May 20, 2025

Karyopharm to Participate at the 2025 RBC Capital Markets Global Healthcare Conference - Eastern Progress

May 20, 2025
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May 19, 2025

Does Karyopharm Therapeutics (KPTI) Have the Potential to Rally 521.62% as Wall Street Analysts Expect? - sharewise

May 19, 2025
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May 19, 2025

Karyopharm to Participate at the 2025 RBC Capital Markets Global Healthcare Conference | KPTI Stock News - GuruFocus

May 19, 2025
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May 16, 2025

StockNews.com Downgrades Karyopharm Therapeutics (NASDAQ:KPTI) to Sell - Defense World

May 16, 2025
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May 16, 2025

Leerink Partnrs Issues Positive Estimate for KPTI Earnings - Defense World

May 16, 2025
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May 16, 2025

Brokerages Set Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Price Target at $45.60 - Defense World

May 16, 2025
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May 16, 2025

Karyopharm targets $1B peak U.S. revenue in myelofibrosis as Phase 3 SENTRY enrollment nears completion - MSN

May 16, 2025
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May 15, 2025

Karyopharm’s Earnings Call: Clinical Gains Amid Financial Strains - TipRanks

May 15, 2025
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May 15, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Q1 2025 Earnings Call Transcript - Insider Monkey

May 15, 2025
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May 15, 2025

Robert W. Baird Issues Pessimistic Forecast for Karyopharm Therapeutics (NASDAQ:KPTI) Stock Price - Defense World

May 15, 2025
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May 15, 2025

Karyopharm Announces Poster Presentation on Selinexor in Myelofi - GuruFocus

May 15, 2025
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May 14, 2025

KPTI to Present Promising Selinexor Data at Upcoming Hematology Meeting | KPTI Stock News - GuruFocus

May 14, 2025
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May 14, 2025

Karyopharm abstract selected for presentation at 2025 EHA meeting - TipRanks

May 14, 2025
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May 14, 2025

Karyopharm Announces Poster Presentation on Selinexor in Myelofibrosis at the 2025 European Hematology Association Annual Meeting - PR Newswire

May 14, 2025
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May 13, 2025

KPTI: RBC Capital Lowers Price Target while Maintaining Outperform Rating | KPTI Stock News - GuruFocus

May 13, 2025
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May 13, 2025

RBC Capital cuts Karyopharm stock price target to $33 By Investing.com - Investing.com Canada

May 13, 2025
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May 13, 2025

KPTI: RBC Capital Lowers Price Target while Maintaining Outperfo - GuruFocus

May 13, 2025
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May 13, 2025

These Analysts Revise Their Forecasts On Karyopharm Therapeutics After Q1 Results - Benzinga

May 13, 2025
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May 13, 2025

KPTI Misses Q1 Revenue Estimates but Advances Myelofibrosis Tria - GuruFocus

May 13, 2025
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May 13, 2025

KPTI Stock Boosted as Barclays Raises Price Target to $10 | KPTI - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm (KPTI) Target Price Reduced by RBC Capital | KPTI Sto - GuruFocus

May 13, 2025
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May 13, 2025

KPTI: Baird Lowers Price Target but Maintains Outperform Rating - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm (KPTI) Price Target Reduced by Baird, Outperform Rati - GuruFocus

May 13, 2025
pulisher
May 13, 2025

Karyopharm Therapeutics Inc Reports Q1 2025 Earnings: EPS Loss o - GuruFocus

May 13, 2025
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May 13, 2025

RBC Adjusts Price Target on Karyopharm Therapeutics to $33 From $43, Maintains Outperform Rating - marketscreener.com

May 13, 2025
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May 13, 2025

Barclays Updates Karyopharm (KPTI) Price Target, Eyes Future Dat - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm Therapeutics Inc (KPTI) Q1 2025 Earnings Call Highlights: Promising Clinical ... - Yahoo Finance

May 13, 2025
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May 13, 2025

Karyopharm Therapeutics Inc (KPTI) Q1 2025 Earnings Call Highlig - GuruFocus

May 13, 2025
pulisher
May 13, 2025

Karyopharm Q1 2025 slides: Myelofibrosis opportunity takes center stage By Investing.com - Investing.com Canada

May 13, 2025
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May 13, 2025

Karyopharm Therapeutics Reports Q1 2025 Earnings and Clinical Progress - TipRanks

May 13, 2025
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May 12, 2025

Earnings call transcript: Karyopharm Q1 2025 shows mixed market reaction By Investing.com - Investing.com Nigeria

May 12, 2025
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May 12, 2025

Karyopharm Reports First Quarter 2025 Financial Results and Announces New Data in Myelofibrosis that Further Suggests Selinexor May Lead to Meaningful Spleen Volume Reduction, Symptom Improvement, Hemoglobin Stabilization and Disease Modificati - Citizen Tribune

May 12, 2025
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May 12, 2025

Earnings call transcript: Karyopharm Q1 2025 shows mixed market reaction - Investing.com

May 12, 2025
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May 12, 2025

KPTI Projects Funding into Early 2026 Supported by XPOVIO Sales - GuruFocus

May 12, 2025
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May 12, 2025

Karyopharm Reports First Quarter 2025 Financial Results and Anno - GuruFocus

May 12, 2025
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May 12, 2025

Karyopharm Therapeutics: Q1 Earnings Snapshot - San Antonio Express-News

May 12, 2025
pulisher
May 12, 2025

Karyopharm Therapeutics (KPTI) Reports Q1 Loss, Lags Revenue Estimates - Yahoo Finance

May 12, 2025
pulisher
May 12, 2025

Karyopharm Q1 2025 slides: Myelofibrosis opportunity takes center stage - Investing.com Australia

May 12, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Karyopharm Therapeutics Inc Stock (KPTI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Rangwala Reshma
EVP & Chief Medical Officer
Apr 23 '25
Sale
6.17
419
2,585
28,853
Paulson Richard A.
President and CEO
Apr 04 '25
Sale
3.74
245
916
82,739
Cheng Sohanya Roshan
EVP & Chief Commercial Officer
Mar 04 '25
Sale
6.29
3,445
21,669
34,314
Paulson Richard A.
President and CEO
Mar 04 '25
Sale
6.29
11,694
73,555
82,984
Rangwala Reshma
EVP & Chief Medical Officer
Mar 04 '25
Sale
6.29
3,587
22,562
29,272
Poulton Stuart
EVP, Chief Development Officer
Mar 04 '25
Sale
6.29
3,548
22,317
27,414
Mano Michael
SVP, General Counsel&Secretary
Mar 04 '25
Sale
6.29
2,793
17,568
21,047
Poulton Stuart
EVP, Chief Development Officer
Feb 18 '25
Sale
0.63
5,914
3,726
320,714
Paulson Richard A.
President and CEO
Feb 04 '25
Sale
0.65
4,099
2,664
1,120,158
Paulson Richard A.
President and CEO
Jan 06 '25
Sale
0.78
4,055
3,175
1,124,257
$1.08
price up icon 1.89%
$30.12
price down icon 3.67%
$572.87
price down icon 1.12%
$304.56
price up icon 3.75%
$4.50
price down icon 3.02%
$489.52
price down icon 19.09%
Cap:     |  Volume (24h):