16.37
price down icon6.24%   -1.09
pre-market  Pre-market:  16.61   0.24   +1.47%
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Lyell Immunopharma Inc stock is traded at $16.37, with a volume of 134.04K. It is down -6.24% in the last 24 hours and down -26.95% over the past month. Lyell Immunopharma Inc s a late-stage clinical cell therapy company advancing a pipeline of proprietary next-generation autologous chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The Company's product candidate, rondecabtagene autoleucel (ronde-cel, also known as LYL314), is an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development for large B-cell lymphoma (LBCL). The Company has recently acquired exclusive rights outside of mainland China, Hong Kong, Macau and Taiwan, to a novel guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate in early clinical development for refractory metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.
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Previous Close:
$17.46
Open:
$17.46
24h Volume:
134.04K
Relative Volume:
1.51
Market Cap:
$381.98M
Revenue:
$36,000
Net Income/Loss:
$-274.45M
P/E Ratio:
-1.3861
EPS:
-11.8105
Net Cash Flow:
$-150.80M
1W Performance:
+1.49%
1M Performance:
-26.95%
6M Performance:
-32.94%
1Y Performance:
+95.77%
1-Day Range:
Value
$16.09
$17.65
1-Week Range:
Value
$16.09
$17.69
52-Week Range:
Value
$7.65
$45.00

Lyell Immunopharma Inc Stock (LYEL) Company Profile

Name
Name
Lyell Immunopharma Inc
Name
Phone
650 695-0677
Name
Address
201 HASKINS WAY, SOUTH SAN FRANCISCO
Name
Employee
161
Name
Twitter
Name
Next Earnings Date
2026-05-12
Name
Latest SEC Filings
Name
LYEL's Discussions on Twitter

Compare LYEL vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
LYEL icon
LYEL
Lyell Immunopharma Inc
16.37 407.41M 36,000 -274.45M -150.80M -11.81
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
435.93 110.28B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
634.62 66.98B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
808.43 50.15B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
295.50 39.71B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
154.89 32.22B 742.00K -1.37B -1.07B -7.0731

Lyell Immunopharma Inc Stock (LYEL) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-26 Initiated Needham Buy
Mar-09-26 Initiated Citizens Mkt Outperform
Dec-09-25 Upgrade H.C. Wainwright Neutral → Buy
Oct-30-24 Downgrade BofA Securities Buy → Underperform
Jun-27-24 Downgrade H.C. Wainwright Buy → Neutral
Aug-28-23 Downgrade JP Morgan Overweight → Neutral
Nov-14-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Nov-11-22 Downgrade Goldman Buy → Neutral
Oct-17-22 Initiated H.C. Wainwright Buy
Jul-12-21 Initiated BofA Securities Buy
Jul-12-21 Initiated Goldman Buy
Jul-12-21 Initiated JP Morgan Overweight
Jul-12-21 Initiated Morgan Stanley Overweight
View All

Lyell Immunopharma Inc Stock (LYEL) Latest News

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04:03 AM

Lyell Immunopharma Targets 2027 FDA Filing as CAR-T Pipeline Advances - Yahoo Finance

04:03 AM
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May 21, 2026

Down 33.7% in 4 Weeks, Here's Why You Should You Buy the Dip in Lyell Immunopharma (LYEL) - MSN

May 21, 2026
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May 21, 2026

Lyell Immunopharma stock (US55083R1041): Analyst boosts price target as cell therapy pipeline advanc - AD HOC NEWS

May 21, 2026
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May 15, 2026

ARCH funds and directors disclose shared control of 3.25M LYEL shares (LYEL) - Stock Titan

May 15, 2026
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May 15, 2026

Lyell Immunopharma (LYEL) Slips -6.23%, Testing $16.95 Support 2026-05-15Crowd Breakout Signals - newser.com

May 15, 2026
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May 15, 2026

Lyell Immunopharma (LYEL) Delivers Q1 2026 Beat — EPS $-1.10 vs $-2.41 ExpectedOperating Margin - Newser

May 15, 2026
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May 14, 2026

LYEL Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

May 14, 2026
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May 12, 2026

Lyell Immunopharma to Participate in Investor Conferences During May - geneonline.com

May 12, 2026
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May 12, 2026

Lyell Immunopharma Announces Participation in May Investor Conferences | Associated Press | syndication news - Enidnews.com

May 12, 2026
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May 12, 2026

Cancer cell therapy firm Lyell offers investor talks online May 19–20 - Stock Titan

May 12, 2026
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May 11, 2026

TradingKey - TradingKey

May 11, 2026
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May 11, 2026

Lyell Immunopharma (LYEL) entities each report 4.3% ownership in amended 13G - Stock Titan

May 11, 2026
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May 10, 2026

Lyell Immunopharma (NASDAQ:LYEL) Upgraded to Hold at Wall Street Zen - MarketBeat

May 10, 2026
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May 08, 2026

Explore Investments/Jeff Bezos report 6.6% stake in Lyell (LYEL) - Stock Titan

May 08, 2026
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May 07, 2026

Lyell Records $24 Mln Loss In Q1, Provides Updates On CAR-T Cell Therapies For Cancer Treatment - RTTNews

May 07, 2026
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May 07, 2026

Lyell Immunopharma: Q1 Earnings Snapshot - theheraldreview.com

May 07, 2026
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May 06, 2026

Lyell starts Phase 3 lymphoma dosing, says cash runway reaches Q3 2027 - Stock Titan

May 06, 2026
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May 06, 2026

Lyell Immunopharma (NASDAQ: LYEL) cuts quarterly loss and raises equity capital - Stock Titan

May 06, 2026
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May 06, 2026

Lyell Immunopharma (NASDAQ: LYEL) trims Q1 loss and advances CAR T trials - Stock Titan

May 06, 2026
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May 06, 2026

BRIEF-Lyell Immunopharma Q1 Net Income USD -24.153 Million - TradingView

May 06, 2026
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May 06, 2026

Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2026 - GlobeNewswire

May 06, 2026
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May 05, 2026

Lyell Immunopharma (LYEL) to Release Quarterly Earnings on Tuesday - MarketBeat

May 05, 2026
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May 04, 2026

Lyell Immunopharma (LYEL) Price Target Increased by 27.27% to 14.28 - MSN

May 04, 2026
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May 03, 2026

LYEL SEC FilingsLyell Immunopharma, Inc. 10-K, 10-Q, 8-K Forms - Stock Titan

May 03, 2026
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May 02, 2026

BofA Securities Maintains Lyell Immunopharma(LYEL.US) With Sell Rating, Maintains Target Price $12 - Moomoo

May 02, 2026
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May 02, 2026

Lyell Immunopharma (NASDAQ:LYEL) Upgraded by Robert W. Baird to Strong-Buy Rating - MarketBeat

May 02, 2026
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May 02, 2026

Lyell Immunopharma (NASDAQ:LYEL) Downgraded to Sell Rating by Wall Street Zen - MarketBeat

May 02, 2026
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May 01, 2026

Baird initiates Lyell Immunopharma stock with outperform rating By Investing.com - Investing.com South Africa

May 01, 2026
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May 01, 2026

Baird initiates Lyell Immunopharma stock with outperform rating - Investing.com

May 01, 2026
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May 01, 2026

Baird Maintains Lyell Immunopharma(LYEL.US) With Buy Rating, Maintains Target Price $49 - Moomoo

May 01, 2026
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May 01, 2026

BofA reiterates Lyell Immunopharma stock Underperform on rival exit By Investing.com - Investing.com Canada

May 01, 2026
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May 01, 2026

BofA reiterates Lyell Immunopharma stock Underperform on rival exit - Investing.com

May 01, 2026
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Apr 30, 2026

Baird Initiates Lyell Immunopharma(LYEL.US) With Buy Rating, Announces Target Price $49 - Moomoo

Apr 30, 2026
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Apr 29, 2026

Lyell Immunopharma climbs after reporting strong CAR T-cell therapy results - MSN

Apr 29, 2026
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Apr 24, 2026

[ARS] Lyell Immunopharma, Inc. SEC Filing - Stock Titan

Apr 24, 2026
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Apr 24, 2026

Lyell Immunopharma (NASDAQ: LYEL) outlines 2026 virtual meeting, board elections and pay vote - Stock Titan

Apr 24, 2026
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Apr 24, 2026

Lyell Immunopharma (NASDAQ:LYEL) Shares Gap DownHere's What Happened - MarketBeat

Apr 24, 2026
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Apr 23, 2026

LYEL (Lyell Immunopharma Inc.) reports far wider than expected Q4 2025 loss as shares tick modestly higher.Pro Level Trade Signals - Cổng thông tin điện tử tỉnh Tây Ninh

Apr 23, 2026
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Apr 21, 2026

Euler Fund (NASDAQ: LYEL) holds 1,426,528 shares, 6.71% stake disclosed - Stock Titan

Apr 21, 2026
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Apr 20, 2026

Lyell Immunopharma (LYEL) Stock: Gaining Traction? (Underperforming) 2026-04-20Retail Money Flow - UBND thành phố Hải Phòng

Apr 20, 2026
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Apr 18, 2026

Lyell Immunopharma (NASDAQ:LYEL) Upgraded by Wall Street Zen to "Hold" Rating - MarketBeat

Apr 18, 2026
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Apr 17, 2026

Lyell Immunopharma, Inc. (NASDAQ:LYEL) Sees Large Increase in Short Interest - MarketBeat

Apr 17, 2026
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Apr 17, 2026

LYEL Earnings History & Surprises | EPS & Revenue Results | LYELL IMMUNOPHARMA INC (NASDAQ:LYEL) - ChartMill

Apr 17, 2026
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Apr 16, 2026

A First Look At Lyell Immunopharma (NASDAQ:LYEL) - Seeking Alpha

Apr 16, 2026
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Apr 15, 2026

[EFFECT] Lyell Immunopharma, Inc. SEC Filing - Stock Titan

Apr 15, 2026
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Apr 15, 2026

Structure Therapeutics Appoints Matthew Lang, J.D. as Chief Operating Officer and General Counsel - The Manila Times

Apr 15, 2026
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Apr 14, 2026

Lyell Immunopharma (NASDAQ:LYEL) Shares Down 4%Should You Sell? - MarketBeat

Apr 14, 2026
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Apr 13, 2026

Lyell Immunopharma (NASDAQ:LYEL) Stock Price Up 6.9%Should You Buy? - MarketBeat

Apr 13, 2026
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Apr 11, 2026

This WhiteFiber Analyst Begins Coverage On A Bullish Note; Here Are Top 4 Initiations For Friday - Sahm

Apr 11, 2026
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Apr 11, 2026

Needham initiates coverage of Lyell Immunopharma (LYEL) with buy recommendation - MSN

Apr 11, 2026

Lyell Immunopharma Inc Stock (LYEL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.66
price down icon 0.98%
$92.25
price up icon 0.12%
$108.87
price up icon 2.48%
$53.86
price down icon 1.17%
ONC ONC
$302.44
price down icon 2.52%
$154.89
price up icon 2.20%
Cap:     |  Volume (24h):