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Madrigal Pharmaceuticals Inc stock is traded at $434.80, with a volume of 265.11K. It is up +2.10% in the last 24 hours and down -9.15% over the past month. Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, and premature mortality. The company's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor agonist designed to target key underlying causes of MASH.
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Previous Close:
$425.85
Open:
$429.86
24h Volume:
265.11K
Relative Volume:
0.79
Market Cap:
$9.87B
Revenue:
-
Net Income/Loss:
$-518.67M
P/E Ratio:
-17.31
EPS:
-25.12
Net Cash Flow:
$-438.32M
1W Performance:
-0.05%
1M Performance:
-9.15%
6M Performance:
+0.83%
1Y Performance:
+35.32%
1-Day Range:
Value
$423.98
$443.61
1-Week Range:
Value
$416.21
$448.13
52-Week Range:
Value
$265.00
$615.00

Madrigal Pharmaceuticals Inc Stock (MDGL) Company Profile

Name
Name
Madrigal Pharmaceuticals Inc
Name
Phone
404-380-9263
Name
Address
200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN, PA
Name
Employee
528
Name
Twitter
@MadrigalPharma
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
MDGL's Discussions on Twitter

Compare MDGL vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
MDGL
Madrigal Pharmaceuticals Inc
434.80 9.67B 0 -518.67M -438.32M -25.12
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
477.89 120.48B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
787.50 81.05B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
749.56 46.33B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
327.30 42.26B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
299.02 32.87B 5.36B 287.73M 924.18M 2.5229

Madrigal Pharmaceuticals Inc Stock (MDGL) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Initiated Barclays Overweight
Jan-06-26 Downgrade Wolfe Research Outperform → Peer Perform
Nov-05-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-03-25 Upgrade BofA Securities Underperform → Neutral
Oct-15-25 Initiated Truist Buy
Sep-04-25 Resumed H.C. Wainwright Buy
Feb-28-25 Upgrade B. Riley Securities Neutral → Buy
Feb-27-25 Reiterated H.C. Wainwright Buy
Jun-28-24 Initiated Cantor Fitzgerald Neutral
Jun-11-24 Initiated Wolfe Research Outperform
Apr-22-24 Initiated BofA Securities Underperform
Mar-15-24 Upgrade B. Riley Securities Sell → Neutral
Mar-06-24 Initiated Citigroup Buy
Feb-26-24 Downgrade B. Riley Securities Neutral → Sell
Dec-20-22 Reiterated Oppenheimer Outperform
Dec-19-22 Reiterated H.C. Wainwright Buy
Dec-19-22 Reiterated Piper Sandler Overweight
Dec-19-22 Upgrade Raymond James Underperform → Mkt Perform
Jul-08-22 Downgrade B. Riley Securities Buy → Neutral
Oct-07-21 Initiated Jefferies Buy
Aug-06-21 Upgrade BMO Capital Markets Market Perform → Outperform
May-20-21 Resumed Goldman Buy
Nov-24-20 Resumed Evercore ISI Outperform
Nov-06-20 Reiterated H.C. Wainwright Buy
Jul-31-20 Initiated Piper Sandler Overweight
Jun-05-20 Initiated BMO Capital Markets Market Perform
May-05-20 Initiated Chardan Capital Markets Buy
Jan-30-20 Initiated Canaccord Genuity Buy
Jan-09-20 Upgrade UBS Neutral → Buy
Nov-07-19 Reiterated H.C. Wainwright Buy
Jun-25-19 Initiated Stifel Hold
Jun-10-19 Upgrade B. Riley FBR Neutral → Buy
Feb-28-19 Reiterated H.C. Wainwright Buy
Feb-22-19 Initiated SVB Leerink Outperform
Jan-23-19 Initiated UBS Neutral
Dec-14-18 Initiated Wolfe Research Outperform
Dec-12-18 Initiated B. Riley FBR Neutral
Nov-19-18 Downgrade Raymond James Mkt Perform → Underperform
Nov-16-18 Upgrade Evercore ISI In-line → Outperform
Sep-04-18 Initiated Citigroup Buy
Aug-06-18 Downgrade Goldman Buy → Neutral
Jun-28-18 Initiated Raymond James Mkt Perform
View All

Madrigal Pharmaceuticals Inc Stock (MDGL) Latest News

pulisher
01:39 AM

A Look At Madrigal Pharmaceuticals (MDGL) Valuation After Recent Share Price Weakness - simplywall.st

01:39 AM
pulisher
Mar 04, 2026

Madrigal Pharmaceuticals: How Noninvasive Data Is Powering a Smarter Clinical Strategy! - Smartkarma

Mar 04, 2026
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Mar 04, 2026

Madrigal Pharmaceuticals, Inc. $MDGL Shares Sold by TD Asset Management Inc - MarketBeat

Mar 04, 2026
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Mar 03, 2026

MDGL: Rezdiffra's growth accelerates with a broad pipeline and strong 2026 financial outlook - TradingView

Mar 03, 2026
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Mar 03, 2026

Intech Investment Management LLC Lowers Holdings in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Mar 03, 2026
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Mar 03, 2026

Madrigal Pharmaceuticals (MDGL) Reports Record 2025 Revenue Driven by Rezdiffra Success - Finviz

Mar 03, 2026
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Mar 03, 2026

Madrigal Pharmaceuticals EVP Dier sells $505k in shares By Investing.com - Investing.com Canada

Mar 03, 2026
pulisher
Mar 02, 2026

Madrigal Pharmaceuticals (NASDAQ:MDGL) CFO Mardi Dier Sells 1,183 Shares - MarketBeat

Mar 02, 2026
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Mar 02, 2026

Madrigal Pharmaceuticals (MDGL) director sale notice: 1,183 shares after RSU vest - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

MADRIGAL PHARMACEUTICALS EVP and CFO Sells Shares to Cover Tax Obligations - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Madrigal (MDGL) CFO has shares sold automatically for tax withholding - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) Stock Analysis: Exploring a 54% Upside Potential in the Biotech Sector - DirectorsTalk Interviews

Mar 02, 2026
pulisher
Mar 02, 2026

Rafferty Asset Management LLC Lowers Stock Holdings in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Mar 02, 2026
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Mar 02, 2026

JPMorgan Chase & Co. Reduces Stake in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Mar 02, 2026
pulisher
Mar 01, 2026

William Blair Investment Management LLC Has $188.88 Million Stock Position in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Mar 01, 2026
pulisher
Feb 28, 2026

Artisan Partners Limited Partnership Acquires 4,683 Shares of Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Feb 28, 2026
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Feb 26, 2026

Madrigal Q4 earnings miss, MASH drug sales drive top line, stock down - MSN

Feb 26, 2026
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Feb 26, 2026

MDGL SEC FilingsMadrigal Pharmac 10-K, 10-Q, 8-K Forms - Stock Titan

Feb 26, 2026
pulisher
Feb 26, 2026

Fox Run Management L.L.C. Takes $1.06 Million Position in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Feb 26, 2026
pulisher
Feb 25, 2026

Why Madrigal Pharmaceuticals (MDGL) Is Down 9.7% After Rezdiffra’s Near US$1 Billion Debut Year - Yahoo Finance

Feb 25, 2026
pulisher
Feb 25, 2026

Exit Recap: Will Madrigal Pharmaceuticals Inc outperform during market ralliesEarnings Summary Report & Weekly Setup with High ROI Potential - baoquankhu1.vn

Feb 25, 2026
pulisher
Feb 25, 2026

Madrigal: The Easiest Money May Have Been Made (NASDAQ:MDGL) - Seeking Alpha

Feb 25, 2026
pulisher
Feb 24, 2026

Director exercises 2,500 Madrigal (MDGL) options at $7.36 - Stock Titan

Feb 24, 2026
pulisher
Feb 24, 2026

Madrigal Pharmaceuticals Reports 2025 Financial Results - MyChesCo

Feb 24, 2026
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Feb 24, 2026

Madrigal Pharmaceuticals to Participate in the TD Cowen 46th Annual Health Care Conference - The Manila Times

Feb 24, 2026
pulisher
Feb 24, 2026

Madrigal to webcast TD Cowen health conference talk Mar. 3 - Stock Titan

Feb 24, 2026
pulisher
Feb 23, 2026

Madrigal Grants Inducement Awards to Five Employees - MyChesCo

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal (MDGL) Q4 2025 Earnings Call Transcript - The Globe and Mail

Feb 23, 2026
pulisher
Feb 23, 2026

A Look At Madrigal Pharmaceuticals (MDGL) Valuation After Rezdiffra’s First Full Year Near US$1b In Sales - simplywall.st

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal Pharmaceuticals, Inc. (MDGL): Investor Outlook Reveals 53% Potential Upside In Biotechnology - DirectorsTalk Interviews

Feb 23, 2026
pulisher
Feb 23, 2026

Vanguard Group Inc. Sells 65,227 Shares of Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal’s Rezdiffra Breakthrough Spurs MASH Pipeline Growth And Valuation Debate - Yahoo Finance

Feb 23, 2026
pulisher
Feb 23, 2026

MASH Drugs Market to hit US$ 929.05 Million by 2033 | North America - openPR.com

Feb 23, 2026
pulisher
Feb 20, 2026

Madrigal Pharmaceuticals Stock: A Deep Dive Into Analyst Perspectives (5 Ratings) - Benzinga

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal Q4 Earnings Miss, MASH Drug Sales Drive Top Line, Stock Down - Bitget

Feb 20, 2026
pulisher
Feb 20, 2026

Is now the right time to enter Madrigal Pharmaceuticals Inc.July 2025 Opening Moves & Safe Entry Momentum Tips - mfd.ru

Feb 20, 2026
pulisher
Feb 20, 2026

MDGL: B of A Securities Maintains Neutral Rating, Lowers Price T - GuruFocus

Feb 20, 2026
pulisher
Feb 20, 2026

Bank of America Issues Pessimistic Forecast for Madrigal Pharmaceuticals (NASDAQ:MDGL) Stock Price - MarketBeat

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 20, 2026
pulisher
Feb 20, 2026

Fiera Capital Corp Lowers Stock Holdings in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal inks licensing deal with China’s Suzhou Ribo for MASH drugs - MSN

Feb 20, 2026
pulisher
Feb 20, 2026

Decoding Madrigal Pharmaceuticals Inc (MDGL): A Strategic SWOT I - GuruFocus

Feb 20, 2026
pulisher
Feb 19, 2026

Madrigal Pharma earnings missed by $1.97, revenue topped estimates - Investing.com Canada

Feb 19, 2026
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Feb 19, 2026

Madrigal Eyes MASH Future As Rezdiffra Nears Blockbuster Revenue - Citeline News & Insights

Feb 19, 2026
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Feb 19, 2026

Earnings call transcript: Madrigal Pharmaceuticals Q4 2025 misses EPS, stock dips - Investing.com India

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals Inc (MDGL) Q4 2025 Earnings Call Highlights: Record Sales and ... By GuruFocus - Investing.com Canada

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals Inc (MDGL) Q4 2025 Earnings Call Highli - GuruFocus

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals (NASDAQ:MDGL) Posts Quarterly Earnings Results, Misses Estimates By $2.61 EPS - MarketBeat

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals, Inc. reports strong Rezdiffra sales growth in Q4 2025; first full year of launch approaches $1 billion in net sales - AlphaStreet News

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals, Inc. Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals (MDGL) Reports Strong Q4 2025 Performan - GuruFocus

Feb 19, 2026

Madrigal Pharmaceuticals Inc Stock (MDGL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$47.43
price down icon 0.11%
$29.52
price up icon 6.00%
$57.80
price up icon 15.99%
$103.80
price up icon 3.02%
$149.88
price up icon 1.96%
biotechnology ONC
$299.02
price up icon 0.67%
Cap:     |  Volume (24h):