85.49
price down icon4.93%   -4.435
pre-market  Pre-market:  85.31   -0.18   -0.21%
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Oruka Therapeutics Inc stock is traded at $85.49, with a volume of 1.29M. It is down -4.93% in the last 24 hours and down -16.53% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$89.92
Open:
$88.83
24h Volume:
1.29M
Relative Volume:
1.19
Market Cap:
$5.66B
Revenue:
-
Net Income/Loss:
$-116.25M
P/E Ratio:
-35.75
EPS:
-2.3912
Net Cash Flow:
$-91.19M
1W Performance:
-12.52%
1M Performance:
-16.53%
6M Performance:
+114.26%
1Y Performance:
+459.86%
1-Day Range:
Value
$82.69
$89.18
1-Week Range:
Value
$82.69
$98.29
52-Week Range:
Value
$14.89
$115.52

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-11-11
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, MRNA, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
85.49 5.66B 0 -116.25M -91.19M -2.3912
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
522.38 132.40B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
796.02 81.95B 14.92B 4.42B 3.79B 41.04
MRNA icon
MRNA
Moderna Inc
194.82 77.78B 2.23B -3.19B -1.60B -8.1462
ARGX icon
ARGX
Argen X Se Adr
962.22 60.20B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
199.86 42.84B 742.00K -1.37B -1.07B -7.0731

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

pulisher
Sep 24, 2026

Oruka Therapeutics, Inc. (ORKA) stock price, news, quote and history - Yahoo Finance UK

Sep 24, 2026
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Sep 24, 2026

Oruka Therapeutics' Psoriasis Treatment Maintains 'Competitive Profile' After Positive Clinical Data, UBS Says - Yahoo Finance

Sep 24, 2026
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Sep 24, 2026

Oruka Therapeutics, Inc. (ORKA) Stock Price, News, Quote & History - Yahoo! Finance Canada

Sep 24, 2026
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Sep 24, 2026

ORKA Stock Down 5% Despite Positive Week 28 Psoriasis Efficacy Data - TradingView

Sep 24, 2026
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Sep 24, 2026

Oruka Therapeutics stock price target maintained at $120 by H.C. Wainwright - Investing.com Canada

Sep 24, 2026
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Sep 23, 2026

Clear Street Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $131 - Moomoo

Sep 23, 2026
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Sep 23, 2026

What Oruka Therapeutics (ORKA)'s Phase 2a Psoriasis Data Means For Shareholders - Yahoo Finance

Sep 23, 2026
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Sep 23, 2026

Oruka Shares Fall Despite Deepening Week 28 Responses for ORKA-001 - marketscreener.com

Sep 23, 2026
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Sep 23, 2026

Update: Oruka Shares Fall Despite Deepening Week 28 Responses for ORKA-001 - Yahoo Finance

Sep 23, 2026
pulisher
Sep 23, 2026

10 Health Care Stocks Whale Activity In Today’s Session - Benzinga

Sep 23, 2026
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Sep 23, 2026

Oruka posts trial data for plaque psoriasis drug (ORKA:NASDAQ) - Seeking Alpha

Sep 23, 2026
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Sep 23, 2026

Oruka Therapeutics Says Psoriasis Drug Shows Deepening Efficacy - AOL.ca

Sep 23, 2026
pulisher
Sep 23, 2026

Why is Oruka Therapeutics stock sliding today? By Investing.com - Investing.com Canada

Sep 23, 2026
pulisher
Sep 23, 2026

Oruka Therapeutics Reports Deepening Responses for ORKA-001 Through Week 28 - marketscreener.com

Sep 23, 2026
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Sep 23, 2026

Oruka Therapeutics Shares Fall 5% After Week 28 ORKA-001 Trial Data - Yahoo Finance

Sep 23, 2026
pulisher
Sep 23, 2026

Oruka Therapeutics stock falls despite positive trial data By Investing.com - Investing.com Australia

Sep 23, 2026
pulisher
Sep 23, 2026

Oruka Therapeutics stock falls despite positive trial data - Investing.com

Sep 23, 2026
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Sep 23, 2026

Oruka reports week 28 psoriasis trial results for ORKA-001 By Investing.com - Investing.com Canada

Sep 23, 2026
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Sep 23, 2026

In a psoriasis trial, 71% had clear skin six months after their last dose - Stock Titan

Sep 23, 2026
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Sep 22, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $936k in stock - Investing.com Nigeria

Sep 22, 2026
pulisher
Sep 22, 2026

Form 4 Oruka Therapeutics Inc For: 22 September By Investing.com - Investing.com Canada

Sep 22, 2026
pulisher
Sep 22, 2026

Form 4 Oruka Therapeutics Inc For: 22 September - Investing.com UK

Sep 22, 2026
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Sep 21, 2026

Details on Warrant Exercise and Subsequent Share Sales by Oruka Therapeutics' General Counsel - Kalkine Media

Sep 21, 2026
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Sep 21, 2026

Oruka Therapeutics SVP Arjun Agarwal Sells 533 Shares Under Rule 10b5-1 Plan - Kalkine Media

Sep 21, 2026
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Sep 21, 2026

Oruka Therapeutics SVP Arjun Agarwal sells $51,034 in ORKA stock By Investing.com - Investing.com South Africa

Sep 21, 2026
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Sep 21, 2026

Oruka Therapeutics SVP Arjun Agarwal sells $51,034 in ORKA stock - Investing.com UK

Sep 21, 2026
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Sep 21, 2026

Oruka Therapeutics Insider Sold Shares Worth $936,417, According to a Recent SEC Filing - marketscreener.com

Sep 21, 2026
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Sep 21, 2026

Oruka Therapeutics (NASDAQ: ORKA) insider plans new share sale after recent 10b5-1 trades - Stock Titan

Sep 21, 2026
pulisher
Sep 18, 2026

ORKA Stock Is Soaring After Psoriasis Trial Results — Here's Why BTIG Hiked Its Price Target By 94% - Stocktwits

Sep 18, 2026
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Sep 18, 2026

Oruka Therapeutics, Inc. (ORKA) Stock Analysis: A 58.6% Potential Upside Beckons Biotech Investors - DirectorsTalk Interviews

Sep 18, 2026
pulisher
Sep 18, 2026

LifeSci Capital Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $175 - Moomoo

Sep 18, 2026
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Sep 17, 2026

Halozyme Therapeutics, Inc. Announces Pricing of Upsized Private Offering of $1.3 Billion of Convertible Senior Notes due 2033 - PR Newswire

Sep 17, 2026
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Sep 16, 2026

Oruka Therapeutics COO Sandler sells $86,713 in common stock By Investing.com - Investing.com South Africa

Sep 16, 2026
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Sep 16, 2026

Oruka Therapeutics chief medical officer Joana Goncalves sells $734k in shares By Investing.com - Investing.com South Africa

Sep 16, 2026
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Sep 16, 2026

Oruka Therapeutics SVP Agarwal sells over $926k in common stock By Investing.com - Investing.com South Africa

Sep 16, 2026
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Sep 15, 2026

Oruka Therapeutics SVP Agarwal sells over $926k in common stock - Investing.com Canada

Sep 15, 2026
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Sep 15, 2026

Oruka Therapeutics CEO Lawrence Klein sells $234,680 in ORKA stock - Investing.com

Sep 15, 2026
pulisher
Sep 15, 2026

Oruka Therapeutics chief medical officer Joana Goncalves sells $734k in shares - Investing.com UK

Sep 15, 2026
pulisher
Sep 15, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $99,442 in stock - Investing.com UK

Sep 15, 2026
pulisher
Sep 15, 2026

Oruka Therapeutics COO Sandler sells $86,713 in common stock - Investing.com

Sep 15, 2026
pulisher
Sep 15, 2026

Oruka Therapeutics CEO Lawrence Klein Executes 2,452-Share Sale for RSU Tax Withholding - Kalkine Media

Sep 15, 2026
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Sep 15, 2026

Oruka Therapeutics SVP Finance Arjun Agarwal Reports Multiple Stock Option Exercises and Sales - Kalkine Media

Sep 15, 2026
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Sep 10, 2026

Oruka Therapeutics to Attend Morgan Stanley Global Healthcare Conference - Bitget

Sep 10, 2026
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Sep 09, 2026

Morgan Stanley's New York healthcare conference includes Oruka - Stock Titan

Sep 09, 2026
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Sep 09, 2026

Oruka Therapeutics to Attend the 2026 Morgan Stanley Global Healthcare Conference - GlobeNewswire

Sep 09, 2026
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Sep 05, 2026

About Oruka Therapeutics Inc aStock - Coinbase

Sep 05, 2026
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Sep 04, 2026

ORKA News | ORUKA THERAPEUTICS INC (NASDAQ:ORKA) - ChartMill

Sep 04, 2026
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Sep 03, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy By Investing.com - Investing.com Canada

Sep 03, 2026
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Sep 03, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy - Investing.com UK

Sep 03, 2026
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Sep 02, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $130 - Moomoo

Sep 02, 2026
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Sep 02, 2026

Oruka Therapeutics CEO Klein sells $6.8m in stock By Investing.com - Investing.com South Africa

Sep 02, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$58.29
price up icon 1.11%
$36.13
price down icon 1.87%
$121.55
price up icon 2.71%
$249.59
price up icon 1.25%
ONC ONC
$359.97
price down icon 1.38%
$199.86
price up icon 4.78%
Cap:     |  Volume (24h):