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Oruka Therapeutics Inc stock is traded at $92.16, with a volume of 578.91K. It is up +0.23% in the last 24 hours and up +12.27% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$91.95
Open:
$92.51
24h Volume:
578.91K
Relative Volume:
0.34
Market Cap:
$5.56B
Revenue:
-
Net Income/Loss:
$-116.25M
P/E Ratio:
-38.54
EPS:
-2.3912
Net Cash Flow:
$-91.19M
1W Performance:
-0.58%
1M Performance:
+12.27%
6M Performance:
+167.98%
1Y Performance:
+547.65%
1-Day Range:
Value
$90.32
$94.49
1-Week Range:
Value
$89.79
$96.27
52-Week Range:
Value
$12.84
$97.78

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-08-10
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
92.16 5.56B 0 -116.25M -91.19M -2.3912
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
477.36 121.16B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
656.01 68.78B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
918.22 57.44B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
189.23 40.23B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
271.77 36.28B 4.29B 577.22M 641.34M 4.2086

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

pulisher
02:50 AM

ORKA|Oruka Therapeutics Inc|Price:92.160|Chg%:+0.210 - TradingKey

02:50 AM
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Jul 24, 2026

ORKA Stock Is Soaring After Psoriasis Trial Results — Here's Why BTIG Hiked Its Price Target By 94% - Stocktwits

Jul 24, 2026
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Jul 17, 2026

Oruka Therapeutics Inc. (ORKA) Stock Price | Live Quotes & Charts | NASDAQ - timothysykes.com

Jul 17, 2026
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Jul 17, 2026

ORKA Stock Climbs As Traders Track Tight Range - StocksToTrade

Jul 17, 2026
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Jul 17, 2026

ORKA Stock Grinds Higher As Traders Track Tight Range - timothysykes.com

Jul 17, 2026
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Jul 17, 2026

ORKA Stock Climbs As Traders Track Strong Cash Runway - StocksToTrade

Jul 17, 2026
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Jul 17, 2026

Oruka Therapeutics Rises as Investors Focus on Pipeline Data Setup - Quiver Quantitative

Jul 17, 2026
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Jul 16, 2026

Form 144 ORUKA THERAPEUTICS INC For: 15 July By Investing.com - Investing.com Australia

Jul 16, 2026
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Jul 16, 2026

Oruka Therapeutics CMO Joana Goncalves sells $603,937 in shares - Investing.com UK

Jul 16, 2026
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Jul 15, 2026

Form 4 Oruka Therapeutics Inc For: 15 July By Investing.com - Investing.com Nigeria

Jul 15, 2026
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Jul 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $603,937 in shares By Investing.com - Investing.com Nigeria

Jul 15, 2026
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Jul 15, 2026

Form 4 Oruka Therapeutics Inc For: 15 July - Investing.com UK

Jul 15, 2026
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Jul 15, 2026

Form 144 ORUKA THERAPEUTICS INC For: 15 July - Investing.com UK

Jul 15, 2026
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Jul 14, 2026

BTIG Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $151 - Moomoo

Jul 14, 2026
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Jul 14, 2026

Form 4 Oruka Therapeutics Inc For: 13 July By Investing.com - Investing.com South Africa

Jul 14, 2026
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Jul 13, 2026

Oruka Therapeutics SVP sells $846k in stock By Investing.com - Investing.com Nigeria

Jul 13, 2026
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Jul 13, 2026

Form 144 Oruka Therapeutics For: 13 July By Investing.com - Investing.com Australia

Jul 13, 2026
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Jul 13, 2026

Oruka Therapeutics Insider Sold Shares Worth $846,180, According to a Recent SEC Filing - Moomoo

Jul 13, 2026
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Jul 13, 2026

Oruka Therapeutics SVP sells $846k in stock - Investing.com

Jul 13, 2026
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Jul 13, 2026

Form 144 Oruka Therapeutics For: 13 July - Investing.com UK

Jul 13, 2026
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Jul 10, 2026

Oruka TherapeuticsIntriguing Long Acting Psoriasis Programs May Need Further Derisking - Seeking Alpha

Jul 10, 2026
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Jul 10, 2026

How Investors May Respond To Oruka Therapeutics (ORKA) Russell Index Shift Toward Small-Cap Growth Benchmarks - simplywall.st

Jul 10, 2026
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Jul 08, 2026

Oruka Therapeutics Shares Drop After Hours After Fairmount Unloads 3.55 Million Shares - MSN

Jul 08, 2026
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Jul 07, 2026

Oruka Therapeutics (ORKA) Recast By Russell Growth Shift On A Valuation That Looks About Right - Sahm

Jul 07, 2026
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Jul 03, 2026

Why Oruka Therapeutics (ORKA) Is Up 13.6% After Russell Index Reclassification Into Growth Benchmarks - Sahm

Jul 03, 2026
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Jul 03, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $130 - Moomoo

Jul 03, 2026
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Jul 02, 2026

Oruka Therapeutics (ORKA) Sees 8.1% Decline - GuruFocus

Jul 02, 2026
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Jul 02, 2026

Oruka Therapeutics Insider Sold Shares Worth $472,079, According to a Recent SEC Filing - marketscreener.com

Jul 02, 2026
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Jul 02, 2026

Fairmount Healthcare Fund II sells $300m Oruka Therapeutics stock By Investing.com - Investing.com India

Jul 02, 2026
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Jul 01, 2026

Form 144 | Oruka Therapeutics(ORKA.US) Insider Proposes to Sell 300.01 Million in Common Stocks - Moomoo

Jul 01, 2026
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Jul 01, 2026

Insider Sell: Laura Sandler Sells 5,000 Shares of Oruka Therapeu - GuruFocus

Jul 01, 2026
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Jul 01, 2026

Form 144 Oruka Therapeutics For: 1 July By Investing.com - Investing.com Nigeria

Jul 01, 2026
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Jul 01, 2026

Form 13D/A ORUKA THERAPEUTICS For: 1 July By Investing.com - Investing.com Nigeria

Jul 01, 2026
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Jul 01, 2026

Fairmount Healthcare Fund II sells $300m Oruka Therapeutics stock - Investing.com

Jul 01, 2026
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Jul 01, 2026

Form 144 Oruka Therapeutics For: 1 July - Investing.com UK

Jul 01, 2026
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Jul 01, 2026

Oruka Therapeutics COO Laura Sandler sells $472,078 in stock - Investing.com

Jul 01, 2026
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Jul 01, 2026

Oruka Therapeutics COO Laura Sandler sells $472,078 in stock By Investing.com - Investing.com South Africa

Jul 01, 2026
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Jul 01, 2026

Form 4 Oruka Therapeutics Inc For: 1 July By Investing.com - Investing.com India

Jul 01, 2026
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Jul 01, 2026

Form 4 Oruka Therapeutics Inc For: 1 July - Investing.com UK

Jul 01, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Oruka Therapeutics Inc Stock (ORKA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Goncalves Joana
Chief Medical Officer
Jul 15 '26
Sale
86.28
7,000
603,938
32,718
$106.92
price down icon 0.46%
$117.67
price up icon 0.84%
$35.01
price down icon 0.26%
$58.83
price down icon 0.32%
ONC ONC
$325.90
price down icon 0.27%
$271.77
price up icon 1.13%
Cap:     |  Volume (24h):