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Oruka Therapeutics Inc stock is traded at $92.51, with a volume of 600.47K. It is up +1.67% in the last 24 hours and down -5.73% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$90.99
Open:
$90.06
24h Volume:
600.47K
Relative Volume:
0.48
Market Cap:
$6.13B
Revenue:
-
Net Income/Loss:
$-116.25M
P/E Ratio:
-38.69
EPS:
-2.3912
Net Cash Flow:
$-91.19M
1W Performance:
+1.50%
1M Performance:
-5.73%
6M Performance:
+164.39%
1Y Performance:
+517.97%
1-Day Range:
Value
$89.38
$94.00
1-Week Range:
Value
$86.00
$96.20
52-Week Range:
Value
$14.66
$115.52

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-08-10
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
92.51 6.94B 0 -116.25M -91.19M -2.3912
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
546.12 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
827.72 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,033.15 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
145.55 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
210.02 45.38B 742.00K -1.37B -1.07B -7.0731

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

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Aug 21, 2026

Oruka Therapeutics Files $1 Billion Mixed Shelf - marketscreener.com

Aug 21, 2026
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Aug 21, 2026

Oruka Therapeutics Inc aStock (AORKA) Price Prediction for 2026 to 2031 - Bybit

Aug 21, 2026
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Aug 21, 2026

Show Me The Money: ORKA Makes A Splash With A 500%+ Gain; More Catalysts Ahead - RTTNews

Aug 21, 2026
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Aug 20, 2026

Oruka (ORKA) Outlook: Finishes 4.40% Lower at $104.86 in the Current Update; Level Watch: Support at $99.62 and Resistance at $110.10 Frame the Range at the CloseFRAMA Signal - Vinanet

Aug 20, 2026
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Aug 20, 2026

RTW Investments, LP Expands Oruka Therapeutics (ORKA) Stake with Strategic Add - GuruFocus

Aug 20, 2026
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Aug 20, 2026

Oruka (ORKA) Earnings Snapshot: The Available Earnings Metric Delivers a Miss in the Available Record; Post-Report: Shares Finish 3.00% Down for the Current SessionEarnings Cycle Outlook - Vinanet

Aug 20, 2026
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Aug 19, 2026

Preferred dividends of Oruka Therapeutics, Inc. – HAM:HQ1 - TradingView

Aug 19, 2026
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Aug 19, 2026

Oruka Therapeutics, Inc. Income Statement – HAM:HQ1 - TradingView

Aug 19, 2026
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Aug 19, 2026

Oruka Therapeutics (ORKA) Is Up 8.0% After Wider Q2 Net LossesHas The Bull Case Changed? - simplywall.st

Aug 19, 2026
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Aug 19, 2026

Oruka Therapeutics, Inc. (NASDAQ:ORKA) Receives Consensus Rating of "Moderate Buy" from Analysts - MarketBeat

Aug 19, 2026
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Aug 18, 2026

Oruka Therapeutics CMO Joana Goncalves sells $782,882 in stock - Investing.com

Aug 18, 2026
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Aug 17, 2026

Joana Goncalves Sells 7,000 Shares of Oruka Therapeutics (NASDAQ:ORKA) Stock - MarketBeat

Aug 17, 2026
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Aug 17, 2026

Oruka Therapeutics (NASDAQ:ORKA) Reaches New 52-Week HighWhat's Next? - MarketBeat

Aug 17, 2026
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Aug 17, 2026

ORKA Q2 2026 Earnings: Wider Loss Reflects R&D Investment as Pre-Revenue Biotech Advances PipelineEarnings Power Value - Vinanet

Aug 17, 2026
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Aug 17, 2026

Biotech Stocks At 52-Week HighsETON +44%, DXCM, ORKA, CON, ATAI - RTTNews

Aug 17, 2026
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Aug 16, 2026

Oruka Therapeutics (NASDAQ:ORKA) Cut to "Sell" at Wall Street Zen - MarketBeat

Aug 16, 2026
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Aug 15, 2026

LifeSci Capital Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $175 - Moomoo

Aug 15, 2026
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Aug 15, 2026

ORKA Stock Is Soaring After Psoriasis Trial Results — Here's Why BTIG Hiked Its Price Target By 94% - Stocktwits

Aug 15, 2026
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Aug 15, 2026

Oruka Therapeutics stock hits 52-week high at 109.56 USD By Investing.com - Investing.com South Africa

Aug 15, 2026
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Aug 14, 2026

Oruka Therapeutics GC Paul Quinlan sells $5.64m stock By Investing.com - Investing.com Canada

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics GC Paul Quinlan sells $5.64m stock - Investing.com

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics senior vice president Arjun Agarwal sells $1.06m By Investing.com - Investing.com Australia

Aug 14, 2026
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Aug 14, 2026

Insider Selling: Oruka Therapeutics (NASDAQ:ORKA) SVP Sells 10,000 Shares of Stock - MarketBeat

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics senior vice president Arjun Agarwal sells $1.06m - Investing.com

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics Insider Sold Shares Worth $5,641,409, According to a Recent SEC Filing - marketscreener.com

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics Insider Sold Shares Worth $1,066,572, According to a Recent SEC Filing - marketscreener.com

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics (ORKA): Venrock group reports 7.4% ownership stake - Stock Titan

Aug 14, 2026
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Aug 14, 2026

ORKA (ORKA) insider Paul Quinlan files to sell 71,000 shares via option exercise - Stock Titan

Aug 14, 2026
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Aug 14, 2026

Viking Global group discloses 1.50M Oruka (ORKA) shares on amended 13G - Stock Titan

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics stock hits 52-week high at 109.56 USD - Investing.com

Aug 14, 2026
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Aug 14, 2026

Oruka Therapeutics (ORKA) gains 5.2% stake holder with 3.14M shares - Stock Titan

Aug 14, 2026
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Aug 14, 2026

Handelsbanken Fonder AB Purchases Shares of 160,900 Oruka Therapeutics, Inc. $ORKA - MarketBeat

Aug 14, 2026
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Aug 13, 2026

Sei Investments Co. Raises Position in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Aug 13, 2026
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Aug 12, 2026

Oruka Therapeutics (ORKA) On Its Earnings Miss And Whether The Valuation Still Holds - Sahm

Aug 12, 2026
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Aug 12, 2026

A Quick Look at Today's Ratings for Oruka Therapeutics(ORKA.US), With a Forecast Between $133 to $180 - Moomoo

Aug 12, 2026
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Aug 12, 2026

Dimensional Fund Advisors LP Makes New Investment in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Aug 12, 2026
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Aug 12, 2026

Capital World Investors (ORKA) reports 5.6% beneficial stake in Oruka Therapeutics - Stock Titan

Aug 12, 2026
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Aug 12, 2026

Wedbush Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $165 - Moomoo

Aug 12, 2026
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Aug 11, 2026

Oruka Therapeutics (ORKA) Is Up 10.9% After Wider-Than-Expected Q2 Loss From R&D InvestmentHas The Bull Case Changed? - simplywall.st

Aug 11, 2026
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Aug 11, 2026

Oruka Therapeutics' (ORKA) "Buy" Rating Reaffirmed at Guggenheim - MarketBeat

Aug 11, 2026
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Aug 11, 2026

Oruka Therapeutics' (ORKA) Outperform Rating Reiterated at Wedbush - MarketBeat

Aug 11, 2026
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Aug 11, 2026

Oruka Therapeutics (NASDAQ:ORKA) Given "Buy" Rating at BTIG Research - MarketBeat

Aug 11, 2026
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Aug 11, 2026

Oruka Therapeutics (NASDAQ:ORKA) Sets New 12-Month HighStill a Buy? - MarketBeat

Aug 11, 2026
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Aug 10, 2026

ORUKA THERAPEUTICS INC : LEERINK PARTNERS RAISES TARGET PRICE TO $179 FROM $162 - Bitget

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics Releases Q2 2026 Financial Results - AlphaStreet

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics Q2 Loss Widens - marketscreener.com

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics Inc reports results for the quarter ended June 30Earnings Summary - TradingView

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics Q2 EPS of $(0.55) misses estimates - scanx.trade

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics (NASDAQ:ORKA) Issues Earnings Results, Misses Expectations By $0.04 EPS - MarketBeat

Aug 10, 2026
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Aug 10, 2026

Earnings Flash (ORKA) Oruka Therapeutics Posts Q2 Loss $0.55 a Share, vs. FactSet Est of $0.53 Loss - marketscreener.com

Aug 10, 2026
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Aug 10, 2026

Oruka Therapeutics Q2 net loss widens on higher R&D costs - TradingView

Aug 10, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Oruka Therapeutics Inc Stock (ORKA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Sandler Laura Lee
Chief Operating Officer
Sep 01 '26
Sale
91.82
5,000
459,101
236,384
Klein Lawrence Otto
Chief Executive Officer
Sep 01 '26
Option Exercise
7.80
75,000
585,000
1,000,580
Klein Lawrence Otto
Chief Executive Officer
Sep 01 '26
Sale
91.83
75,000
6,887,484
925,580
$103.76
price up icon 0.86%
$126.29
price down icon 0.31%
$63.96
price up icon 0.13%
$266.11
price up icon 0.61%
ONC ONC
$358.26
price down icon 1.22%
$210.02
price down icon 0.40%
Cap:     |  Volume (24h):