65.55
price down icon2.25%   -1.51
after-market After Hours: 66.19 0.64 +0.98%
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Oruka Therapeutics Inc stock is traded at $65.55, with a volume of 1.40M. It is down -2.25% in the last 24 hours and up +63.87% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$67.06
Open:
$67.45
24h Volume:
1.40M
Relative Volume:
2.11
Market Cap:
$3.25B
Revenue:
-
Net Income/Loss:
$-105.43M
P/E Ratio:
-28.28
EPS:
-2.3183
Net Cash Flow:
$-88.42M
1W Performance:
+5.71%
1M Performance:
+63.87%
6M Performance:
+134.86%
1Y Performance:
+665.77%
1-Day Range:
Value
$64.88
$67.94
1-Week Range:
Value
$59.00
$67.94
52-Week Range:
Value
$8.31
$67.94

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-03-12
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
65.55 3.32B 0 -105.43M -88.42M -2.3183
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.70 113.01B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
753.93 79.87B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
840.87 51.51B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
333.39 45.29B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
319.94 34.41B 5.36B 287.73M 924.18M 2.5229

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

pulisher
08:16 AM

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy By Investing.com - Investing.com Canada

08:16 AM
pulisher
Apr 14, 2026

Oruka Therapeutics stock hits 52-week high at 64.72 USD By Investing.com - Investing.com Australia

Apr 14, 2026
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Apr 14, 2026

The Psoriasis Clinical Trial Pipeline Boom as 90+ Companies are in the Race for Better Treatments | DelveInsight - The Manila Times

Apr 14, 2026
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Apr 14, 2026

The Psoriasis Clinical Trial Pipeline Boom as 90+ Companies are in the Race for Better Treatments | DelveInsight - GlobeNewswire Inc.

Apr 14, 2026
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Apr 14, 2026

Does Oruka Therapeutics' (ORKA) US$1 Billion Shelf Clarify or Complicate Its Capital Strategy? - simplywall.st

Apr 14, 2026
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Apr 13, 2026

ORKA Maintained by BTIG -- Price Target Raised to $78 - GuruFocus

Apr 13, 2026
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Apr 13, 2026

H.C. Wainwright raises Oruka Therapeutics price target to $70 - Investing.com

Apr 13, 2026
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Apr 13, 2026

H.C. Wainwright raises Oruka Therapeutics price target to $70 By Investing.com - Investing.com Canada

Apr 13, 2026
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Apr 13, 2026

BTIG raises Oruka Therapeutics price target on trial timeline By Investing.com - Investing.com Canada

Apr 13, 2026
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Apr 13, 2026

Up nearly 840% in a year, does this 'strong buy' stock have more room to run? - MSN

Apr 13, 2026
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Apr 13, 2026

[EFFECT] Oruka Therapeutics, Inc. SEC Filing - Stock Titan

Apr 13, 2026
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Apr 10, 2026

This Startup’s Psoriasis Drug Studies Have Lifted Its Stock - Barron's

Apr 10, 2026
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Apr 08, 2026

Stifel reiterates Oruka Therapeutics stock rating ahead of trial data By Investing.com - Investing.com Canada

Apr 08, 2026
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Apr 08, 2026

ORKA Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Apr 08, 2026
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Apr 08, 2026

Up Nearly 840% in a Year, Does This ‘Strong Buy’ Stock Have More Room to Run? - Yahoo Finance

Apr 08, 2026
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Apr 08, 2026

Oruka Therapeutics (NASDAQ:ORKA) Shares Up 5% After Analyst Upgrade - Defense World

Apr 08, 2026
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Apr 07, 2026

How cyclical is Oruka Therapeutics Incs revenue streamPrice Action & Community Verified Watchlist Alerts - baoquankhu1.vn

Apr 07, 2026
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Apr 07, 2026

Oruka Therapeutics Is Maintained at Overweight by Barclays - Moomoo

Apr 07, 2026
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Apr 07, 2026

UBS Sticks to Its Buy Rating for Oruka Therapeutics (ORKA) - The Globe and Mail

Apr 07, 2026
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Apr 07, 2026

Barclays Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Raises Target Price to $78 - Moomoo

Apr 07, 2026
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Apr 07, 2026

Oruka Therapeutics (NASDAQ:ORKA) Given New $75.00 Price Target at UBS Group - Defense World

Apr 07, 2026
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Apr 06, 2026

Does Oruka Therapeutics' (ORKA) $1 Billion Shelf Plan Reframe Its Long-Term Capital Strategy? - Sahm

Apr 06, 2026
pulisher
Apr 06, 2026

Oruka Therapeutics (NASDAQ:ORKA) Price Target Raised to $75.00 at UBS Group - MarketBeat

Apr 06, 2026
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Apr 06, 2026

Oruka Therapeutics (NASDAQ:ORKA) Hits New 52-Week HighHere's Why - MarketBeat

Apr 06, 2026
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Apr 06, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Raises Target Price to $75 - Moomoo

Apr 06, 2026
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Apr 06, 2026

Guggenheim raises Oruka Therapeutics price target on trial outlook By Investing.com - Investing.com Canada

Apr 06, 2026
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Apr 06, 2026

Secure Asset Management LLC Takes Position in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Apr 06, 2026
pulisher
Apr 04, 2026

ORKA Financials: Revenue Breakdown, Margins & Competitor Comparison - Intellectia AI

Apr 04, 2026
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Apr 02, 2026

Oruka Therapeutics may offer up to $1 billion of securities from time to timeSEC filing - marketscreener.com

Apr 02, 2026
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Apr 02, 2026

Oruka Therapeutics May Offer Up To $1 Billion Of Securities From Time To TimeSEC Filing - TradingView

Apr 02, 2026
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Apr 02, 2026

Oruka Therapeutics (NASDAQ: ORKA) files $1B shelf to sell equity, warrants - Stock Titan

Apr 02, 2026
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Apr 01, 2026

Oruka Therapeutics stock hits 52-week high at 50.11 USD By Investing.com - Investing.com Australia

Apr 01, 2026
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Apr 01, 2026

HC Wainwright & Co. Maintains Oruka Therapeutics (ORKA) Buy Recommendation - MSN

Apr 01, 2026
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Apr 01, 2026

ORKA-001 Phase 1 Completion: What Oruka’s First-in-Human Milestone Means for Investors - TipRanks

Apr 01, 2026
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Apr 01, 2026

Oruka Therapeutics stock hits 52-week high at 50.11 USD - Investing.com

Apr 01, 2026
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Mar 31, 2026

Oruka Therapeutics (NASDAQ:ORKA) Sets New 12-Month HighShould You Buy? - MarketBeat

Mar 31, 2026
pulisher
Mar 30, 2026

Oruka Therapeutics, Inc. (NASDAQ:ORKA) Short Interest Down 18.4% in March - MarketBeat

Mar 30, 2026
pulisher
Mar 30, 2026

How does Oruka Therapeutics Inc compare to its peersProfit Target & Low Risk High Reward Trade Ideas - baoquankhu1.vn

Mar 30, 2026
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Mar 29, 2026

Oruka Therapeutics and Clearmind Medicine Vie for Investor Dollars - National Today

Mar 29, 2026
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Mar 27, 2026

Vanguard realignment leaves Oruka Therapeutics (ORKA) holdings at 0 after disaggregation - Stock Titan

Mar 27, 2026
pulisher
Mar 27, 2026

458,946 Shares in Oruka Therapeutics, Inc. $ORKA Acquired by Synergy Asset Management LLC - marketbeat.com

Mar 27, 2026
pulisher
Mar 26, 2026

Oruka Therapeutics (NASDAQ:ORKA) Shares Up 5.6%Here's Why - MarketBeat

Mar 26, 2026
pulisher
Mar 26, 2026

Oruka Therapeutics stock hits 52-week high at 43.0 USD By Investing.com - Investing.com Australia

Mar 26, 2026
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Mar 25, 2026

Momentum Shift: Will Oruka Therapeutics Inc benefit from AI trendsQuarterly Profit Report & Accurate Entry and Exit Point Alerts - baoquankhu1.vn

Mar 25, 2026
pulisher
Mar 25, 2026

Oruka Therapeutics (NASDAQ:ORKA) Hits New 12-Month HighShould You Buy? - MarketBeat

Mar 25, 2026
pulisher
Mar 25, 2026

Oruka Therapeutics stock hits 52-week high at 43.0 USD - Investing.com

Mar 25, 2026
pulisher
Mar 25, 2026

Aug Selloffs: Will Oruka Therapeutics Inc outperform tech stocksQuarterly Investment Review & AI Powered Market Entry Strategies - baoquankhu1.vn

Mar 25, 2026
pulisher
Mar 24, 2026

Does Oruka’s Widening Loss and ESOP Shelf Registration Change The Bull Case For Oruka Therapeutics (ORKA)? - Yahoo Finance

Mar 24, 2026
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Mar 24, 2026

Piper Sandler reiterates Oruka Therapeutics stock rating at Overweight By Investing.com - Investing.com Canada

Mar 24, 2026
pulisher
Mar 24, 2026

Piper Sandler reiterates Oruka Therapeutics stock rating at Overweight - Investing.com

Mar 24, 2026
pulisher
Mar 22, 2026

Oruka Therapeutics, Inc.: Fundamental Analysis and Financial Ratings | | US6876041087 - marketscreener.com

Mar 22, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$54.26
price up icon 2.69%
$48.70
price down icon 0.25%
$99.47
price up icon 1.08%
$152.54
price up icon 3.76%
$146.74
price down icon 4.34%
ONC ONC
$319.94
price up icon 3.21%
Cap:     |  Volume (24h):