27.81
price up icon4.47%   1.19
after-market After Hours: 27.81
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Oruka Therapeutics Inc stock is traded at $27.81, with a volume of 453.81K. It is up +4.47% in the last 24 hours and down -9.82% over the past month. Oruka Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its lead program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. The company's co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, psoriatic arthritis (PsA), and other conditions. These programs each bind their respective targets at high affinity and incorporate half-life extension technology to increase exposure and decreasing dosing frequency.
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Previous Close:
$26.62
Open:
$27.27
24h Volume:
453.81K
Relative Volume:
0.87
Market Cap:
$1.35B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
-8.25%
1M Performance:
-9.82%
6M Performance:
+109.26%
1Y Performance:
+46.45%
1-Day Range:
Value
$26.78
$28.51
1-Week Range:
Value
$25.23
$30.61
52-Week Range:
Value
$5.485
$32.64

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
28
Name
Twitter
Name
Next Earnings Date
2024-11-04
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ORKA
Oruka Therapeutics Inc
27.81 1.29B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
484.15 118.84B 11.74B 3.68B 3.34B 14.19
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REGN
Regeneron Pharmaceuticals Inc
812.27 81.61B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
422.50 53.69B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
822.94 49.49B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
176.00 37.34B 447.02M -1.18B -906.14M -6.1812

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

pulisher
Jan 06, 2026

Oruka Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference - The Manila Times

Jan 06, 2026
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Jan 06, 2026

Oruka Therapeutics, Inc. (NASDAQ:ORKA) Receives Consensus Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Jan 06, 2026
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Jan 05, 2026

Oruka Therapeutics: ORKA-001 For Psoriasis In Focus As 2026 Phase 2 Data Nears - Seeking Alpha

Jan 05, 2026
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Jan 05, 2026

ORKA-001 psoriasis trial: Fresh phase 2 update and what it means for investors - MSN

Jan 05, 2026
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Jan 05, 2026

Oruka Therapeutics (NASDAQ:ORKA) Trading Down 8.3%What's Next? - MarketBeat

Jan 05, 2026
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Jan 05, 2026

Oruka Therapeutics Builds Oncology Programs at Molecular Level - Kalkine Media

Jan 05, 2026
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Jan 02, 2026

Insider Sell Alert: Laura Sandler Sells 13,000 Shares of Oruka T - GuruFocus

Jan 02, 2026
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Jan 02, 2026

Oruka Therapeutics COO Sandler sells $370,795 in shares By Investing.com - Investing.com Canada

Jan 02, 2026
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Jan 02, 2026

Oruka Therapeutics COO Sandler sells $370,795 in shares - Investing.com UK

Jan 02, 2026
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Jan 02, 2026

Oruka Therapeutics (NASDAQ:ORKA) Stock Price Up 4.3% – Time to Buy? - Defense World

Jan 02, 2026
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Dec 31, 2025

Oruka Therapeutics (NASDAQ:ORKA) Shares Up 4.3%Should You Buy? - MarketBeat

Dec 31, 2025
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Dec 30, 2025

Oruka Therapeutics (NASDAQ:ORKA) Trading Down 3.3%Time to Sell? - MarketBeat

Dec 30, 2025
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Dec 29, 2025

Wolfe Research Initiates Coverage of Oruka Therapeutics (ORKA) with Outperform Recommendation - MSN

Dec 29, 2025
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Dec 28, 2025

Rigel Pharmaceuticals (NASDAQ:RIGL) and Oruka Therapeutics (NASDAQ:ORKA) Financial Survey - Defense World

Dec 28, 2025
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Dec 26, 2025

Oruka Therapeutics inks exclusive license deal with Paragon - MSN

Dec 26, 2025
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Dec 23, 2025

Oruka Therapeutics (ORKA): Valuation Check After Board Appointment of Commercial Veteran Chris Martin - Sahm

Dec 23, 2025
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Dec 22, 2025

Oruka Therapeutics (NASDAQ:ORKA) Reaches New 12-Month HighHere's What Happened - MarketBeat

Dec 22, 2025
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Dec 22, 2025

Oruka Therapeutics stock hits 52-week high at 32.31 USD By Investing.com - Investing.com Australia

Dec 22, 2025
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Dec 22, 2025

Oruka Therapeutics stock hits 52-week high at 32.31 USD - Investing.com India

Dec 22, 2025
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Dec 20, 2025

Is Oruka Therapeutics Inc. (HQ1) stock undervalued historicallyMarket Sentiment Report & Fast Exit Strategy with Risk Control - Улправда

Dec 20, 2025
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Dec 20, 2025

Financial Enhancement Group LLC Takes Position in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Dec 20, 2025
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Dec 19, 2025

Oruka Therapeutics (NASDAQ:ORKA) Insider Sells $214,270.00 in Stock - MarketBeat

Dec 19, 2025
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Dec 19, 2025

Oruka Therapeutics (NASDAQ:ORKA) Shares Up 11.3%Here's What Happened - MarketBeat

Dec 19, 2025
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Dec 19, 2025

Why Oruka Therapeutics Inc. stock is a must watch in 2025Recession Risk & Real-Time Chart Pattern Alerts - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Piper Sandler Begins Coverage on Oruka Therapeutics (NASDAQ:ORKA) - MarketBeat

Dec 19, 2025
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Dec 19, 2025

How Oruka Therapeutics Inc. stock compares to growth peersWeekly Gains Report & AI Based Buy and Sell Signals - Улправда

Dec 19, 2025
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Dec 18, 2025

Is Oruka Therapeutics Inc. stock a dividend growth opportunityJuly 2025 PreEarnings & Weekly Chart Analysis and Trade Guides - Улправда

Dec 18, 2025
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Dec 18, 2025

ORKA-001 Psoriasis Trial: Fresh Phase 2 Update and What It Means for Investors - TipRanks

Dec 18, 2025
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Dec 15, 2025

Oruka Therapeutics Earnings Notes - Trefis

Dec 15, 2025
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Dec 13, 2025

Braidwell LP Cuts Stake in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Dec 13, 2025
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Dec 12, 2025

Oruka Therapeutics appoints Chris Martin to board of directors By Investing.com - Investing.com India

Dec 12, 2025
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Dec 12, 2025

Oruka Therapeutics, Inc. (NASDAQ:ORKA) Receives Average Rating of "Moderate Buy" from Analysts - MarketBeat

Dec 12, 2025
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Dec 11, 2025

Oruka Therapeutics appoints Chris Martin to board of directors - Investing.com

Dec 11, 2025
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Dec 11, 2025

Oruka Therapeutics Appoints Christopher Martin to Board - TipRanks

Dec 11, 2025
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Dec 11, 2025

Oruka Therapeutics Announces New Board Member and Board Transition - The Manila Times

Dec 11, 2025
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Dec 09, 2025

B Group Inc. Increases Position in Oruka Therapeutics, Inc. $ORKA - Defense World

Dec 09, 2025
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Dec 06, 2025

Oruka Therapeutics (ORKA) Stock Analysis Report | Financials & Insights - Benzinga

Dec 06, 2025
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Dec 06, 2025

Oruka Therapeutics, Inc. $ORKA Shares Purchased by Geode Capital Management LLC - Defense World

Dec 06, 2025
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Dec 06, 2025

Oruka Therapeutics, Inc. $ORKA Shares Purchased by Affinity Asset Advisors LLC - Defense World

Dec 06, 2025
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Dec 05, 2025

Oruka Therapeutics (NASDAQ:ORKA) Sets New 52-Week HighWhat's Next? - MarketBeat

Dec 05, 2025
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Dec 05, 2025

Oruka Therapeutics stock hits 52-week high, reaching $31.01 By Investing.com - Investing.com Nigeria

Dec 05, 2025
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Dec 05, 2025

Can Oruka Therapeutics Inc. stock deliver consistent earnings growthCEO Change & AI Based Buy and Sell Signals - Newser

Dec 05, 2025
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Dec 04, 2025

Will Oruka Therapeutics Inc. stock sustain high P E ratios2025 Volatility Report & Safe Capital Growth Plans - Newser

Dec 04, 2025
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Dec 04, 2025

Is Oruka Therapeutics Inc. (HQ1) stock dividend growth reliable2025 Risk Factors & Consistent Profit Trading Strategies - Newser

Dec 04, 2025
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Dec 04, 2025

Oruka Therapeutics stock hits 52-week high, reaching $31.01 - Investing.com

Dec 04, 2025
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Dec 04, 2025

Should I hold or sell Oruka Therapeutics Inc. stock in 2025Market Movement Recap & AI Based Buy and Sell Signals - Newser

Dec 04, 2025
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Dec 04, 2025

Is Oruka Therapeutics Inc. (HQ1) stock undervalued at current priceJuly 2025 Snapshot & Community Verified Trade Alerts - Newser

Dec 04, 2025
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Dec 04, 2025

Is Oruka Therapeutics Inc. (HQ1) stock a momentum leaderQuarterly Portfolio Review & Long-Term Safe Investment Plans - Newser

Dec 04, 2025
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Dec 03, 2025

Will Oruka Therapeutics Inc. stock see insider buyingMarket Growth Review & Consistent Profit Trading Strategies - Newser

Dec 03, 2025

Oruka Therapeutics Inc Stock (ORKA) Financials Data

There is no financial data for Oruka Therapeutics Inc (ORKA). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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Oruka Therapeutics Inc Stock (ORKA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Sandler Laura Lee
Chief Operating Officer
Jan 02 '26
Sale
28.52
13,000
370,795
205,084
$102.71
price up icon 28.63%
$33.90
price up icon 2.42%
$110.57
price up icon 3.67%
$100.08
price up icon 2.03%
biotechnology ONC
$333.87
price up icon 4.22%
$176.00
price up icon 0.53%
Cap:     |  Volume (24h):