68.95
price up icon3.75%   2.49
after-market After Hours: 68.50 -0.45 -0.65%
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Oruka Therapeutics Inc stock is traded at $68.95, with a volume of 2.04M. It is up +3.75% in the last 24 hours and up +29.34% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$66.46
Open:
$67.17
24h Volume:
2.04M
Relative Volume:
1.79
Market Cap:
$4.13B
Revenue:
-
Net Income/Loss:
$-105.43M
P/E Ratio:
-29.74
EPS:
-2.3183
Net Cash Flow:
$-88.42M
1W Performance:
-6.81%
1M Performance:
+29.34%
6M Performance:
+152.47%
1Y Performance:
+590.88%
1-Day Range:
Value
$65.00
$69.28
1-Week Range:
Value
$60.98
$76.37
52-Week Range:
Value
$8.91
$91.00

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-05-13
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
68.95 3.98B 0 -105.43M -88.42M -2.3183
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
424.36 109.34B 12.32B 4.34B 3.19B 16.86
REGN icon
REGN
Regeneron Pharmaceuticals Inc
702.27 74.35B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
794.70 50.44B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
301.11 39.78B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
297.49 33.02B 5.36B 287.73M 924.18M 2.5229

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

pulisher
May 04, 2026

Oruka Therapeutics shares jump on strong psoriasis trial results - MSN

May 04, 2026
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May 04, 2026

Fairmount funds keep 19.99% Oruka (ORKA) stake under 45-day lock-up - Stock Titan

May 04, 2026
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May 04, 2026

Assessing Oruka Therapeutics (ORKA) Valuation After Phase 2a Psoriasis Success And Once‑Yearly Dosing Potential - Sahm

May 04, 2026
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May 04, 2026

Oruka Therapeutics Insider Sold Shares Worth $319,384, According to a Recent SEC Filing - marketscreener.com

May 04, 2026
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May 02, 2026

ORKA SEC FilingsOruka Therapeutics Inc 10-K, 10-Q, 8-K Forms - Stock Titan

May 02, 2026
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May 01, 2026

Oruka Therapeutics COO Laura Sandler sells $319,384 in Orka shares By Investing.com - Investing.com Canada

May 01, 2026
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May 01, 2026

Oruka Therapeutics COO Laura Sandler sells $319,384 in Orka shares - Investing.com

May 01, 2026
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May 01, 2026

Oruka Therapeutics (ORKA) COO sells 5,000 shares and exercises 5,000-share warrant - Stock Titan

May 01, 2026
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May 01, 2026

Oruka Therapeutics Completes Public Equity Offering Under Shelf - The Globe and Mail

May 01, 2026
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May 01, 2026

Three biotechs raise $850M+ in upsized IPOs, gain in aftermarket: Public Equity Report - biocentury.com

May 01, 2026
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May 01, 2026

Finance Watch: Avalyn, Hemab And Seaport Launch $856m Worth Of IPOs - Citeline News & Insights

May 01, 2026
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May 01, 2026

Laura Sandler to sell 10,000 ORKA shares (ORKA) via option exercise - Stock Titan

May 01, 2026
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May 01, 2026

Oruka Therapeutics (NASDAQ:ORKA) Trading Down 5.9%Here's Why - MarketBeat

May 01, 2026
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May 01, 2026

Q2 EPS Estimate for Oruka Therapeutics Boosted by Analyst - MarketBeat

May 01, 2026
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May 01, 2026

Oruka Therapeutics prices upsized $700M public offering at $72.50 per share - MSN

May 01, 2026
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Apr 30, 2026

Oruka Therapeutics (ORKA) price target increased by 34.40% to 91.96 - MSN

Apr 30, 2026
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Apr 30, 2026

Oruka Therapeutics (ORKA) sells 9.66M shares at $72.50 in underwritten deal - Stock Titan

Apr 30, 2026
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Apr 30, 2026

Oruka Therapeutics (ORKA) Reports Positive Phase 2a Results for Psoriasis Treatment ORKA-001 - Yahoo Finance

Apr 30, 2026
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Apr 30, 2026

Oruka Therapeutics, Inc. (NASDAQ:ORKA) Short Interest Up 22.4% in April - MarketBeat

Apr 30, 2026
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Apr 29, 2026

Oruka Therapeutics, Inc. (ORKA) Discusses Interim Results From EVERLAST-A Study of ORKA-001 in Moderate to Severe Plaque PsoriasisSlideshow (NASDAQ:ORKA) 2026-04-29 - Seeking Alpha

Apr 29, 2026
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Apr 29, 2026

Oruka Therapeutics (ORKA) offers 9.66M shares, raising ~$658M net - Stock Titan

Apr 29, 2026
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Apr 29, 2026

Oruka Therapeutics (NASDAQ:ORKA) Sees Unusually-High Trading VolumeTime to Buy? - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Moody Aldrich Partners LLC Takes $3.84 Million Position in Oruka Therapeutics, Inc. $ORKA - MarketBeat

Apr 29, 2026
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Apr 29, 2026

H.C. Wainwright raises Oruka Therapeutics price target to $120 on trial data - Investing.com Canada

Apr 29, 2026
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Apr 29, 2026

Oruka Therapeutics Shares Surpass Record High After Psoriasis Trial - HarianBasis.co

Apr 29, 2026
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Apr 29, 2026

Oruka Therapeutics Prices Upsized $700 Million Share Offering - marketscreener.com

Apr 29, 2026
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Apr 28, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Raises Target Price to $100 - Moomoo

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics prices $700M stock offering at $72.50/share By Investing.com - Investing.com Australia

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics Announces Pricing of Upsized $700 Million Underwritten Public Offering - The Manila Times

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics prices $700M stock offering at $72.50/share - Investing.com

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics, Inc. Prices Upsized Public Offering of 9.66 Million Shares at $72.50 Per Share - Quiver Quantitative

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics announces pricing of upsized $700 million underwritten public offering - marketscreener.com

Apr 28, 2026
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Apr 28, 2026

Biotech Oruka locks in $700M cash raise at $72.50 a share - Stock Titan

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics Announces Pricing Of Upsized $700 Million Underwritten Public Offering - TradingView

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics (NASDAQ:ORKA) Trading 6.6% HigherWhat's Next? - MarketBeat

Apr 28, 2026
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Apr 28, 2026

ORKA stock is soaring after psoriasis trial results — here's why BTIG hiked its price target by 94% - MSN

Apr 28, 2026
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Apr 28, 2026

OGN Soars 16.87%, ORKA Hits Record on Healthcare Catalysts - Gotrade

Apr 28, 2026
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Apr 28, 2026

UBS Lifts Price Target on Oruka Therapeutics to $100 From $75, Maintains Buy Rating - marketscreener.com

Apr 28, 2026
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Apr 28, 2026

Oruka reports positive data from Phase IIa trial for plaque psoriasis - Yahoo

Apr 28, 2026
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Apr 28, 2026

Oruka Therapeutics stock hits 52-week high at 90.06 USD By Investing.com - Investing.com South Africa

Apr 28, 2026
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Apr 27, 2026

Oruka Therapeutics Touts “Category-Winning” ORKA-001 Data, Targets Once-Yearly Psoriasis Dosing - MarketBeat

Apr 27, 2026
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Apr 27, 2026

5 Stocks Racking Up Monster Gains - Insider Monkey

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics (ORKA) Hits Record High on Stellar Clinical Trial Result - Yahoo Finance

Apr 27, 2026
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Apr 27, 2026

Oruka’s ORKA-001 achieves 63.5% complete skin clearance in trial - Investing.com UK

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics stock explodes as psoriasis data shows 'highly compelling' skin clearance - MSN

Apr 27, 2026
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Apr 27, 2026

New data suggest Oruka’s IL-23 mAb could be competitive in psoriasis - BioCentury

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics Stock Surges After Psoriasis Drug Data as Biotech Seeks $500 Million - TechStock²

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics (ORKA) seeks to sell common stock under shelf prospectus - Stock Titan

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics (ORKA) registers $500M shelf for stock and warrants - Stock Titan

Apr 27, 2026
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Apr 27, 2026

Clear Street raises Oruka Therapeutics price target on trial results By Investing.com - Investing.com Canada

Apr 27, 2026
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Apr 27, 2026

Oruka Therapeutics launches $500 million stock offering By Investing.com - Investing.com Australia

Apr 27, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$28.32
price down icon 0.14%
$50.44
price up icon 0.48%
$95.50
price down icon 3.88%
$139.44
price down icon 0.41%
$147.21
price down icon 0.47%
ONC ONC
$297.49
price up icon 0.12%
Cap:     |  Volume (24h):