60.61
price up icon3.27%   1.92
after-market After Hours: 60.61
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Oruka Therapeutics Inc stock is traded at $60.61, with a volume of 1.10M. It is up +3.27% in the last 24 hours and down -13.02% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$58.69
Open:
$58.97
24h Volume:
1.10M
Relative Volume:
0.81
Market Cap:
$3.66B
Revenue:
-
Net Income/Loss:
$-105.43M
P/E Ratio:
-26.14
EPS:
-2.3183
Net Cash Flow:
$-88.42M
1W Performance:
-2.13%
1M Performance:
-13.02%
6M Performance:
+106.93%
1Y Performance:
+441.64%
1-Day Range:
Value
$57.98
$61.15
1-Week Range:
Value
$54.99
$62.17
52-Week Range:
Value
$10.63
$91.00

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-05-13
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
60.61 3.54B 0 -105.43M -88.42M -2.3183
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.52 110.03B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
638.88 67.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
806.46 50.76B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
297.45 40.12B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
151.56 32.68B 742.00K -1.37B -1.07B -7.0731

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

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May 23, 2026

Oruka Therapeutics(ORKA.US) Director Sells US$6.19 Million in Common Stock - Moomoo

May 23, 2026
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May 22, 2026

Oruka Therapeutics director Carl Dambkowski sells $6.19m in stock - Investing.com UK

May 22, 2026
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May 22, 2026

Oruka Therapeutics director Carl Dambkowski sells $6.19m in stock By Investing.com - Investing.com Canada

May 22, 2026
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May 22, 2026

Oruka Insider Sells $463K in Stock as Shares Skyrocket 650%, but Here's What Matters for Investors - AOL.com

May 22, 2026
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May 22, 2026

Oruka Therapeutics (ORKA) director sells 105,000 shares, exercises 62,260 options - Stock Titan

May 22, 2026
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May 21, 2026

105,000 common shares proposed for sale by ORKA (NASDAQ: ORKA) - Stock Titan

May 21, 2026
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May 18, 2026

Oruka Therapeutics SVP Arjun Agarwal sells $607,806 in stock By Investing.com - Investing.com Australia

May 18, 2026
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May 18, 2026

Oruka Therapeutics (ORKA) finance SVP sells 10,290 shares under plan - Stock Titan

May 18, 2026
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May 18, 2026

Oruka Therapeutics Price Target Maintained With a $120.00/Share by HC Wainwright & Co. - Moomoo

May 18, 2026
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May 18, 2026

ORKA (NASDAQ: ORKA) insiders list 22,206 common shares for sale - Stock Titan

May 18, 2026
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May 18, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy By Investing.com - Investing.com Canada

May 18, 2026
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May 18, 2026

ORKA Reiterated by HC Wainwright & Co. -- Price Target Maintained at $120 - GuruFocus

May 18, 2026
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May 17, 2026

How Investors May Respond To Oruka Therapeutics (ORKA) Psoriasis Data And Upsized US$700 Million Offering - Sahm

May 17, 2026
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May 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $432,935 in stock - Investing.com UK

May 15, 2026
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May 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $432,935 in stock By Investing.com - Investing.com Canada

May 15, 2026
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May 15, 2026

Oruka Therapeutics (ORKA) CMO sells 7,000 shares after option exercises under 10b5-1 plan - Stock Titan

May 15, 2026
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May 15, 2026

LifeSci Capital Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $125 - Moomoo

May 15, 2026
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May 15, 2026

Viking shows 2.67M-share stake in Oruka Therapeutics (ORKA) - Stock Titan

May 15, 2026
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May 15, 2026

Oruka Therapeutics (ORKA) Valuation Check After Psoriasis Trial Progress Partnerships And Fresh Funding - Yahoo Finance

May 15, 2026
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May 15, 2026

ORKA's Outperform Rating Reiterated At Wedbush, Eyes Key Psoriasis Data In 2H 2026 - RTTNews

May 15, 2026
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May 15, 2026

Oruka Therapeutics (ORKA) price target increased by 50.51% to 138.41 - MSN

May 15, 2026
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May 14, 2026

A Quick Look at Today's Ratings for Oruka Therapeutics(ORKA.US), With a Forecast Between $151 to $180 - Moomoo

May 14, 2026
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May 14, 2026

Oruka Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update - The Manila Times

May 14, 2026
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May 14, 2026

Oruka Reports 63.5% PASI 100 Rate for ORKA-001 at Week 16 in Psoriasis - The Clinical Trial Vanguard

May 14, 2026
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May 13, 2026

ORKA Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

May 13, 2026
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May 13, 2026

Earnings Flash (ORKA) Oruka Therapeutics Posts Q1 Per Share Loss $0.48, vs. FactSet Est of Loss $0.55 - marketscreener.com

May 13, 2026
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May 13, 2026

Earnings Flash (ORKA) Oruka Therapeutics Posts Q1 Per Share Loss $0.48, Vs. FactSet Est of Loss $0.55 - Moomoo

May 13, 2026
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May 13, 2026

Why This Biotech Fund Increased Its Oruka Therapeutics Stake Amid a Staggering 500% Rally - Yahoo Finance

May 13, 2026
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May 13, 2026

Press Release: Oruka Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update - Moomoo

May 13, 2026
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May 13, 2026

Oruka Therapeutics, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026 - marketscreener.com

May 13, 2026
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May 13, 2026

Oruka Therapeutics (ORKA) ramps R&D and raises over $700M in new equity - Stock Titan

May 13, 2026
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May 13, 2026

ETFs Investing in Oruka Therapeutics, Inc. Stocks - TradingView

May 13, 2026
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May 12, 2026

Assessing Oruka Therapeutics (ORKA) Valuation After Equity Raise Collaboration Deal And Trial Updates - Sahm

May 12, 2026
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May 11, 2026

A Tiny Biotech Just Beat AbbVie's $17 Billion Drug. Should Investors Be Worried? - The Motley Fool

May 11, 2026
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May 11, 2026

HALOZYME REPORTS FIRST QUARTER 2026 RESULTS AND REITERATES 2026 FINANCIAL GUIDANCE - PR Newswire

May 11, 2026
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May 11, 2026

A Tiny Biotech Just Beat AbbVie's $17 Billion Drug. Should Investors Be Worried? - The Motley Fool

May 11, 2026
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May 10, 2026

Leerink Partners Lifts PT on Oruka Therapeutics, Inc. (ORKA) - Insider Monkey

May 10, 2026
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May 10, 2026

ORKA stock is soaring after psoriasis trial results — here's why BTIG hiked its price target by 94% - MSN

May 10, 2026
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May 10, 2026

Why Oruka Therapeutics (ORKA) Is Down 6.3% After $700 Million Follow-On Amid Psoriasis Breakthrough - Yahoo Finance

May 10, 2026
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May 09, 2026

Oruka Therapeutics shares jump on strong psoriasis trial results - MSN

May 09, 2026
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May 08, 2026

5 Best Performing Healthcare Stocks So Far in 2026 - Insider Monkey

May 08, 2026
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May 08, 2026

Psoriasis Data, Halozyme Pact and Equity Raise Might Change The Case For Investing In Oruka Therapeutics (ORKA) - Sahm

May 08, 2026
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May 08, 2026

Oruka Therapeutics, Inc. (ORKA) Stock Analysis: Biotech's 121.89% Potential Upside Captivates Investors - DirectorsTalk Interviews

May 08, 2026
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May 08, 2026

MSN Money - MSN

May 08, 2026
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May 08, 2026

Halozyme (HALO) Enters Global Partnership with Oruka Therapeutics - GuruFocus

May 08, 2026
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May 07, 2026

Oruka Therapeutics (ORKA) slides 8.2% as investors digest recent $700M equity raise - Quiver Quantitative

May 07, 2026
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May 07, 2026

Halozyme and Oruka sign agreement for Hypercon technology - Yahoo Finance

May 07, 2026
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May 06, 2026

Halozyme Agrees to License Hypercon Technology to Oruka to Develop Psoriasis Treatment - Contract Pharma

May 06, 2026
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May 06, 2026

Halozyme licenses Hypercon technology to Oruka for psoriasis drug By Investing.com - Investing.com South Africa

May 06, 2026
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May 06, 2026

Halozyme licenses Hypercon technology to Oruka for psoriasis drug - Investing.com

May 06, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.96
price down icon 2.98%
$106.24
price down icon 3.00%
$92.14
price up icon 1.33%
$54.50
price up icon 1.77%
ONC ONC
$310.25
price up icon 0.20%
$151.56
price down icon 1.41%
Cap:     |  Volume (24h):