72.34
price up icon2.06%   1.46
after-market After Hours: 72.69 0.35 +0.48%
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Oruka Therapeutics Inc stock is traded at $72.34, with a volume of 2.99M. It is up +2.06% in the last 24 hours and up +24.00% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$70.88
Open:
$73.2
24h Volume:
2.99M
Relative Volume:
1.92
Market Cap:
$4.36B
Revenue:
-
Net Income/Loss:
$-116.25M
P/E Ratio:
-30.25
EPS:
-2.3912
Net Cash Flow:
$-91.19M
1W Performance:
+5.65%
1M Performance:
+24.00%
6M Performance:
+156.98%
1Y Performance:
+503.84%
1-Day Range:
Value
$70.90
$74.74
1-Week Range:
Value
$66.68
$74.74
52-Week Range:
Value
$10.77
$91.00

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-08-10
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
72.34 4.27B 0 -116.25M -91.19M -2.3912
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
451.63 116.49B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
609.94 63.73B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.72 55.49B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
278.09 37.75B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
162.99 33.54B 742.00K -1.37B -1.07B -7.0731

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

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Jun 18, 2026

Oruka Therapeutics Inc (ORKA) Institutional Confidence - TradingKey

Jun 18, 2026
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Jun 18, 2026

Oruka Therapeutics Inc (ORKA) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 18, 2026
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Jun 18, 2026

Oruka Therapeutics Inc (ORKA) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 18, 2026
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Jun 18, 2026

Oruka Therapeutics Inc (ORKA) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 18, 2026
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Jun 18, 2026

Oruka Therapeutics Inc (ORKA) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 18, 2026
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Jun 17, 2026

ORKA Q1 2026 Earnings: Narrowed Loss Beats Expectations as Pipeline Development AcceleratesEarnings Yield Spread - newsline.com

Jun 17, 2026
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Jun 17, 2026

Oruka Therapeutics Inc (ORKA) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 15, 2026

Oruka Therapeutics SVP of finance Arjun Agarwal sells $687k in stock - Investing.com UK

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics COO Laura Sandler sells $41,814 in ORKA shares - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics CEO Lawrence Klein sells $120,494 in stock - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $51,082 in stock - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $550,606 in stock - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $550,606 in stock By Investing.com - Investing.com Canada

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics SVP of finance Arjun Agarwal sells $687k in stock By Investing.com - Investing.com India

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $51,082 in stock By Investing.com - Investing.com India

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) SVP exercises options, sells shares to cover tax obligations - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) CMO sells shares and exercises stock options - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) CEO has 1,729 shares sold for RSU tax withholding - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) COO sells 600 shares to cover taxes - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) counsel sells 733 shares in tax sell-to-cover - Stock Titan

Jun 15, 2026
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Jun 14, 2026

Wall Street Analysts Believe Oruka Therapeutics, Inc. (ORKA) Could Rally 111.13%: Here's is How to Trade - MSN

Jun 14, 2026
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Jun 12, 2026

Insider Sell: Carl Dambkowski Sells 35,000 Shares of Oruka Thera - GuruFocus

Jun 12, 2026
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Jun 12, 2026

Certain Warrants of Oruka Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 13-JUN-2026. - marketscreener.com

Jun 12, 2026
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Jun 12, 2026

Certain Series B Preferred Stock of Oruka Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 13-JUN-2026. - marketscreener.com

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics (ORKA) director sells 35,000 shares under Rule 10b5-1 plan - Stock Titan

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics, Inc. (ORKA) upgraded to buy: What does it mean for the stock? - MSN

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics, Inc. (ORKA) Upgraded to Buy: What Does It Mean for the Stock? - Yahoo Finance

Jun 12, 2026
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Jun 11, 2026

ORKA (NASDAQ: ORKA) notice to sell 35,000 shares; insider sold 105,000 - Stock Titan

Jun 11, 2026
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Jun 11, 2026

ORKA Stock Is Soaring After Psoriasis Trial Results — Here's Why BTIG Hiked Its Price Target By 94% - Stocktwits

Jun 11, 2026
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Jun 10, 2026

ORKA News | ORUKA THERAPEUTICS INC (NASDAQ:ORKA) - ChartMill

Jun 10, 2026
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Jun 07, 2026

Basic earnings per share (basic EPS) of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 07, 2026
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Jun 07, 2026

Is Oruka’s Broadened IL-23 License Reshaping Optionality And Altering The Investment Case For Oruka Therapeutics (ORKA)? - simplywall.st

Jun 07, 2026
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Jun 06, 2026

Gross margin % of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Asset turnover of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Oruka Therapeutics, Inc. Statistics – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Oruka Therapeutics, Inc. Income Statement – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

ETFs Investing in Oruka Therapeutics, Inc. Stocks - TradingView

Jun 06, 2026
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Jun 05, 2026

Halozyme licenses Hypercon technology to Oruka for psoriasis drug - Investing.com

Jun 05, 2026
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Jun 04, 2026

ORKA Q1 2026 Earnings: EPS Beat Drives Stock RallyPost-Earnings Drift - newsline.com

Jun 04, 2026
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Jun 04, 2026

Oruka Therapeutics Shareholders Back Governance and Executive Pay - TipRanks

Jun 04, 2026
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Jun 04, 2026

Oruka Therapeutics (ORKA) investors approve directors, auditor and executive pay - Stock Titan

Jun 04, 2026
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Jun 04, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy By Investing.com - Investing.com South Africa

Jun 04, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) director awarded 9,136 stock options with 2036 expiry - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) grants director 9,136 stock options - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Director at Oruka Therapeutics (ORKA) receives 9,136 stock options award - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) director granted 9,136 stock options - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (NASDAQ: ORKA) grants 9,136-share option to Fairmount-managed funds - Stock Titan

Jun 03, 2026
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Jun 03, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy - Investing.com

Jun 03, 2026
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Jun 03, 2026

UBS Sticks to Its Buy Rating for Oruka Therapeutics (ORKA) - The Globe and Mail

Jun 03, 2026
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Jun 02, 2026

Oruka Therapeutics stock rating reaffirmed by Piper Sandler at Overweight - Investing.com Canada

Jun 02, 2026
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Jun 02, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $100 - Moomoo

Jun 02, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$31.43
price up icon 0.74%
$90.89
price down icon 1.44%
$52.96
price down icon 1.38%
$63.96
price up icon 3.50%
ONC ONC
$270.15
price up icon 2.84%
$162.99
price up icon 3.31%
Cap:     |  Volume (24h):