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Puma Biotechnology Inc stock is traded at $9.83, with a volume of 406.59K. It is down -6.56% in the last 24 hours and up +4.69% over the past month. Puma Biotechnology Inc is a biopharmaceutical company that develops and commercializes inventive products to enhance cancer care and improve treatment outcomes for patients. It is currently commercializing NERLYNX, an oral version of neratinib, for the treatment of HER2-positive breast cancer. Also, it is developing Alisertib, a selective, small-molecule inhibitor of aurora kinase A that is designed to disrupt mitosis, resulting in apoptosis of rapidly proliferating tumor cells that are dependent on aurora kinase A.
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Previous Close:
$10.52
Open:
$10.51
24h Volume:
406.59K
Relative Volume:
1.21
Market Cap:
$507.43M
Revenue:
$227.18M
Net Income/Loss:
$24.38M
P/E Ratio:
20.59
EPS:
0.4774
Net Cash Flow:
$53.60M
1W Performance:
-4.47%
1M Performance:
+4.69%
6M Performance:
+35.77%
1Y Performance:
+81.70%
1-Day Range:
Value
$9.81
$10.51
1-Week Range:
Value
$9.81
$10.72
52-Week Range:
Value
$4.575
$10.72

Puma Biotechnology Inc Stock (PBYI) Company Profile

Name
Name
Puma Biotechnology Inc
Name
Phone
(424) 248-6500
Name
Address
10880 WILSHIRE BLVD., LOS ANGELES, CA
Name
Employee
179
Name
Twitter
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
PBYI's Discussions on Twitter

Compare PBYI vs VRTX, MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PBYI icon
PBYI
Puma Biotechnology Inc
9.83 507.43M 227.18M 24.38M 53.60M 0.4774
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
499.74 126.66B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
218.01 87.04B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
790.74 81.41B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
819.14 51.51B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
369.06 41.75B 5.76B 514.49M 1.10B 4.4813

Puma Biotechnology Inc Stock (PBYI) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-28-21 Upgrade Citigroup Neutral → Buy
Jun-25-20 Resumed BofA/Merrill Underperform
Oct-08-19 Downgrade Goldman Neutral → Sell
May-10-19 Downgrade Cantor Fitzgerald Overweight → Neutral
May-10-19 Downgrade Citigroup Buy → Neutral
Jan-17-19 Initiated Leerink Partners Mkt Perform
Jan-03-19 Downgrade Guggenheim Buy → Neutral
Nov-19-18 Upgrade Goldman Sell → Neutral
Nov-02-18 Downgrade BofA/Merrill Buy → Underperform
Nov-02-18 Downgrade JP Morgan Neutral → Underweight
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Sep-17-18 Initiated Goldman Sell
May-11-18 Reiterated Stifel Buy
Nov-10-17 Reiterated Citigroup Buy
Nov-10-17 Reiterated RBC Capital Mkts Sector Perform
Oct-02-17 Reiterated Stifel Buy
Sep-11-17 Reiterated Credit Suisse Outperform
Jul-10-17 Resumed Leerink Partners Outperform
Jun-06-17 Reiterated RBC Capital Mkts Sector Perform
May-25-17 Reiterated RBC Capital Mkts Sector Perform
Mar-02-17 Reiterated RBC Capital Mkts Sector Perform
View All

Puma Biotechnology Inc Stock (PBYI) Latest News

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Oct 16, 2026

4 Breast Cancer Stocks to Watch During Breast Cancer Awareness Month - Zacks Investment Research

Oct 16, 2026
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Oct 13, 2026

Puma Biotechnology grants shares. TD Cowen targets Puma Biotechnology stock at USD 6.00 - ad-hoc-news.de

Oct 13, 2026
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Oct 12, 2026

Puma Biotechnology Reports Q2 2026 Results: Full Earnings Call Transcript - Benzinga

Oct 12, 2026
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Oct 09, 2026

how InvestingPro’s fair value caught Puma Biotech’s 95% surge By Investing.com - Investing.com

Oct 09, 2026
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Oct 07, 2026

Puma Biotechnology stock fell 1.76 percent after award news - AD HOC NEWS

Oct 07, 2026
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Oct 06, 2026

Form 13D/A Puma Biotechnology For: 6 October By Investing.com - Investing.com Canada

Oct 06, 2026
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Oct 06, 2026

Form 13D/A Puma Biotechnology For: 6 October By Investing.com - Investing.com UK

Oct 06, 2026
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Oct 06, 2026

A CEO's $16-per-share warrant expired unexercised at Puma Biotechnology (PBYI). - Stock Titan

Oct 06, 2026
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Oct 06, 2026

Alan H. Auerbach's 2.1M Puma Biotechnology Warrants Expire Without Exercise - Kalkine Media

Oct 06, 2026
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Oct 06, 2026

Puma Biotechnology Reports Inducement Award Under Nasdaq Listing Rule 5635(c)(4)October 5, 2026 - BioSpace

Oct 06, 2026
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Oct 05, 2026

Puma Biotechnology Reports Inducement Award Under Nasdaq Listing Rule 5635(C)(4) - TradingView

Oct 05, 2026
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Oct 05, 2026

Puma Biotechnology, Inc. (PBYI) Stock Price, News, Quote & History - Yahoo! Finance Canada

Oct 05, 2026
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Oct 01, 2026

Puma Biotechnology Inc (NASDAQ: PBYI) Share Price, PBYI Stock News, PBYI Share Price & Updates - Kalkine

Oct 01, 2026
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Sep 25, 2026

Puma Biotechnology Inc (NASDAQ: PBYI) Share Price, PBYI Stock News, PBYI Share Price & Updates - kalkine.ca

Sep 25, 2026
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Sep 18, 2026

PBYI's Alisertib Combo Phase II Study in Small Cell Lung Cancer Begins - Yahoo Finance

Sep 18, 2026
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Sep 17, 2026

Puma Biotechnology Initiates ALISCA®-Lung2, a Phase II Trial of Alisertib in Combination with Paclitaxel for the Treatment of Patients with Advanced Small Cell Lung Cancer - BioSpace

Sep 17, 2026
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Sep 17, 2026

Puma Biotechnology initiates phase II lung cancer trial - Investing.com

Sep 17, 2026
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Sep 17, 2026

Puma Biotechnology Initiates ALISCA®-Lung2, a Phase II Trial of Alisertib in Combination with Paclitaxel for the Treatment of Patients with Advanced Small Cell Lung Cancer - Yahoo Finance

Sep 17, 2026
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Sep 17, 2026

About 50 patients with small cell lung cancer will join Puma's new trial. - Stock Titan

Sep 17, 2026
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Sep 16, 2026

Puma Biotechnology director Troy Wilson sells $45,500 in stock - Investing.com

Sep 16, 2026
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Sep 16, 2026

Puma Biotechnology (NASDAQ: PBYI) director exercises 50K options, sells 62K shares - Stock Titan

Sep 16, 2026
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Sep 16, 2026

Puma Biotechnology (PBYI) Trades Essentially Flat at $9.26, Holding Above $8.80 SupportSweep Order Flow - careplusvn.com

Sep 16, 2026
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Sep 14, 2026

Puma Biotechnology (PBYI) director lines up $45.5K stock sale - Stock Titan

Sep 14, 2026
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Sep 14, 2026

Insider at Puma Biotechnology (NASDAQ: PBYI) files notice to sell shares - Stock Titan

Sep 14, 2026
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Sep 10, 2026

Puma Biotechnology CEO Alan Auerbach presents at H.C. Wainwright Global Investment Conference - Bitget

Sep 10, 2026
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Sep 09, 2026

Puma Biotechnology to Present at H.C. Wainwright’s 28th Annual Global Investment Conference - BioSpace

Sep 09, 2026
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Sep 09, 2026

Puma Biotechnology to Present at H.C. Wainwright’s 28th Annual Global Investment Conference - Yahoo Finance

Sep 09, 2026
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Sep 09, 2026

Axsome (AXSM) Down 3.7% Since Last Earnings Report: Can It Rebound? - Zacks Investment Research

Sep 09, 2026
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Sep 08, 2026

Puma Biotechnology: NERLYNX Funds Their Potential Next Oncology Franchise (NASDAQ:PBYI) - Seeking Alpha

Sep 08, 2026
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Sep 07, 2026

Puma Biotechnology Stock Rises 19% in 3 Months: Here's Why - Eastern Progress

Sep 07, 2026
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Sep 03, 2026

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)September 3, 2026 - biospace.com

Sep 03, 2026
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Sep 03, 2026

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(C)(4) - TradingView

Sep 03, 2026
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Sep 03, 2026

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4) - Yahoo Finance

Sep 03, 2026
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Sep 03, 2026

InvestingPro’s fair value model spotted Puma Biotech’s 95% rally By Investing.com - Investing.com

Sep 03, 2026
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Aug 26, 2026

Puma Biotechnology (PBYI) Pulls Back 1.93% to $9.14, Pressing Closer to Key SupportMcClellan Summation - vinanet.vn

Aug 26, 2026
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Aug 26, 2026

Puma Biotechnology (PBYI) Pulls Back 1.93% to $9.14, Pressing Closer to Key SupportWeak Sell Signals - dars.gov.et

Aug 26, 2026
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Aug 23, 2026

PBYI | PUMA BIOTECHNOLOGY INC FinancialsRevenue Breakdown - Quiver Quantitative

Aug 23, 2026
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Aug 21, 2026

Puma (PBYI) Latest Quarter: The Available Earnings Metric Delivers a Beat; Investor Response: The Stock Ends Down 4.00% for the Current SessionEarnings Turnaround - vinanet.vn

Aug 21, 2026
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Aug 19, 2026

Puma (PBYI) Latest Quarter: EPS Lands Above Forecast in the Current Update; Trading Move: Shares Move 4.76% Up in the Latest SessionEPS Growth Report - vinanet.vn

Aug 19, 2026
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Aug 15, 2026

Puma Biotechnology (NASDAQ:PBYI) Upgraded at Wall Street Zen - MarketBeat

Aug 15, 2026
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Aug 14, 2026

Puma Biotechnology (PBYI) Q2 2026 Earnings Call Transcript - The Globe and Mail

Aug 14, 2026
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Aug 14, 2026

Puma Biotechnology (PBYI) Q2 2026 Earnings Call Transcript - The Globe and Mail

Aug 14, 2026
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Aug 14, 2026

Puma Biotechnology (PBYI) Q2 2026 Earnings Call Transcript - AOL.com

Aug 14, 2026
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Aug 12, 2026

Is Puma Biotechnology (PBYI) a Great Value Stock Right Now? - Yahoo Finance

Aug 12, 2026
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Aug 10, 2026

Puma Biotechnology, Inc. 2026 Q2ResultsEarnings Call Presentation (NASDAQ:PBYI) 2026-08-10 - Seeking Alpha

Aug 10, 2026
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Aug 08, 2026

Puma Biotechnology Reports $56.5M Revenue and Profitability in Q2 - sekbernews.id

Aug 08, 2026
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Aug 08, 2026

Puma Biotechnology (PBYI) Stock Jumps On Profit Strength As Earnings Outlook Fades - Sahm

Aug 08, 2026
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Aug 07, 2026

Puma Biotechnology (NASDAQ:PBYI) Issues Earnings Results, Beats Expectations By $0.15 EPS - MarketBeat

Aug 07, 2026
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Aug 07, 2026

Puma Biotechnology Inc (PBYI) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Aug 07, 2026
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Aug 07, 2026

Puma Biotech earnings beat by $0.16, revenue topped estimates - Investing.com Nigeria

Aug 07, 2026

Puma Biotechnology Inc Stock (PBYI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Puma Biotechnology Inc Stock (PBYI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
WILSON TROY EDWARD
Director
Sep 14 '26
Proposed Sale
9.10
5,000
45,500
0
Cesano Alessandra
Director
Sep 14 '26
Option Exercise
2.93
50,000
146,500
118,850
Cesano Alessandra
Director
Sep 14 '26
Proposed Sale
9.10
62,150
565,565
0
Cesano Alessandra
Director
Sep 14 '26
Sale
9.12
62,150
566,994
56,700
AUERBACH ALAN H
Officer
Jul 06 '26
Proposed Sale
8.26
44,058
364,042
0
HUNT DOUGLAS M
Officer
Jul 06 '26
Proposed Sale
8.26
8,460
69,903
0
NOUGUES MAXIMO F
Officer
Jul 06 '26
Proposed Sale
8.26
9,386
77,555
0
AUERBACH ALAN H
President and CEO
Jul 06 '26
Sale
8.26
44,058
364,051
7,261,671
HUNT DOUGLAS M
See Remarks
Jul 06 '26
Sale
8.26
8,460
69,905
196,841
NOUGUES MAXIMO F
Chief Financial Officer
Jul 06 '26
Sale
8.26
9,386
77,557
230,637
$6.58
price down icon 4.22%
$9.94
price down icon 3.21%
$5.53
price down icon 3.66%
$11.27
price down icon 6.16%
$18.60
price down icon 1.74%
WVE WVE
$3.13
price down icon 1.88%
Cap:     |  Volume (24h):