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Prelude Therapeutics Inc stock is traded at $3.26, with a volume of 479.27K. It is down -1.81% in the last 24 hours and down -27.07% over the past month. Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
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Previous Close:
$3.32
Open:
$3.32
24h Volume:
479.27K
Relative Volume:
1.15
Market Cap:
$260.16M
Revenue:
$16.72M
Net Income/Loss:
$-77.80M
P/E Ratio:
-3.0833
EPS:
-1.0573
Net Cash Flow:
$-43.78M
1W Performance:
-16.20%
1M Performance:
-27.07%
6M Performance:
-26.41%
1Y Performance:
+148.85%
1-Day Range:
Value
$3.18
$3.41
1-Week Range:
Value
$3.18
$3.94
52-Week Range:
Value
$1.16
$6.83

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
79
Name
Twitter
Name
Next Earnings Date
2026-11-11
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD vs VRTX, MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRLD icon
PRLD
Prelude Therapeutics Inc
3.26 260.16M 16.72M -77.80M -43.78M -1.0573
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
499.74 126.66B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
218.01 87.04B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
790.74 81.41B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
819.14 51.51B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
369.06 41.75B 5.76B 514.49M 1.10B 4.4813

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-17-26 Initiated JP Morgan Overweight
May-04-26 Initiated D. Boral Capital Buy
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

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Oct 14, 2026

H.C. Wainwright reiterates Prelude Therapeutics stock rating at buy By Investing.com - Investing.com Canada

Oct 14, 2026
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Oct 14, 2026

Citizens reiterates Prelude Therapeutics stock rating on Lilly deal By Investing.com - Investing.com UK

Oct 14, 2026
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Oct 13, 2026

Wainwright targets Prelude Therapeutics stock at USD 8.00 - ad-hoc-news.de

Oct 13, 2026
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Oct 13, 2026

Prelude Therapeutics Teams Up With Lilly To Test Experimental Breast Cancer Drug In Phase 1 Trial - Yahoo Finance

Oct 13, 2026
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Oct 13, 2026

Lilly will supply two drugs for Prelude's planned breast cancer trial. - Stock Titan

Oct 13, 2026
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Oct 13, 2026

Prelude Announces Clinical Trial Collaboration and Supply Agreement with Lilly to Evaluate KAT6A Selective Degrader PRT13722 in Combination with Verzenio® and Inluriyo® in Patients with HR+/HER2- Breast Cancer - GlobeNewswire

Oct 13, 2026
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Oct 06, 2026

Prelude Therapeutics stock gains 2.72 percent as targets stay high - AD HOC NEWS

Oct 06, 2026
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Sep 23, 2026

Prelude Therapeutics stock falls 9.9 percent despite FDA progress - AD HOC NEWS

Sep 23, 2026
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Sep 20, 2026

Prelude Therapeutics Incorporated(NasdaqGS: PRLD) added to S&P Global BMI Index - marketscreener.com

Sep 20, 2026
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Sep 20, 2026

Prelude Therapeutics stock gains as FDA clears new breast cancer drug trial - AD HOC NEWS

Sep 20, 2026
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Sep 16, 2026

Prelude Therapeutics at H.C. Wainwright conference: pipeline gains momentum By Investing.com - Investing.com Canada

Sep 16, 2026
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Sep 13, 2026

Prelude Wins FDA Clearance to Move Breast Cancer Drug to Trial - MyChesCo

Sep 13, 2026
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Sep 11, 2026

Prelude Therapeutics to Participate in the H.C. Wainwright 28th Annual Global Investment Conference - The Manila Times

Sep 11, 2026
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Sep 11, 2026

Four executives will join Prelude’s fireside chat Sept. 16 - Stock Titan

Sep 11, 2026
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Sep 11, 2026

Prelude Therapeutics to Participate in the H.C. Wainwright 28th Annual Global Investment Conference - GlobeNewswire

Sep 11, 2026
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Sep 11, 2026

Prelude Therapeutics to Participate in the H.C. Wainwright 28th Annual Global Investment Conference - Yahoo Finance

Sep 11, 2026
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Sep 10, 2026

Prelude Therapeutics Receives FDA Clearance for New Drug Clinical Trial - Intellectia AI

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics (PRLD) Gains FDA Nod for Phase 1 Trial in B - GuruFocus

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics Cleared by FDA for Phase 1 Breast Cancer Drug Trial - marketscreener.com

Sep 10, 2026
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Sep 10, 2026

Prelude gets FDA clearance for breast cancer drug trial - Investing.com

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics receives FDA clearance for PRT13722 IND application - TipRanks

Sep 10, 2026
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Sep 10, 2026

Prelude gets FDA clearance for breast cancer drug trial By Investing.com - Investing.com India

Sep 10, 2026
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Sep 10, 2026

Prelude gets FDA clearance for breast cancer drug trial By Investing.com - Investing.com UK

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics Receives FDA Clearance of - GlobeNewswire

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics Receives FDA Clearance of Investigational New Drug (IND) Application for PRT13722, Its First-in-Class Oral KAT6A Selective Degrader - Yahoo Finance

Sep 10, 2026
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Sep 10, 2026

FDA clears first human study of a breast cancer drug candidate. Prelude expects enrollment in Q4 2026. - Stock Titan

Sep 10, 2026
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Sep 10, 2026

Prelude Therapeutics Cleared by FDA for Phase 1 Breast Cancer Drug Trial - Yahoo Finance

Sep 10, 2026
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Sep 06, 2026

Neuraptive Therapeutics, Inc. Announces Key Org… | UNI India - uniindia.com

Sep 06, 2026
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Aug 23, 2026

Prelude Therapeutics: A Prognosis After Year Long Rally (NASDAQ:PRLD) - Seeking Alpha

Aug 23, 2026
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Aug 21, 2026

Prelude Therapeutics (NASDAQ:PRLD) Reaches New 1-Year HighStill a Buy? - MarketBeat

Aug 21, 2026
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Aug 20, 2026

Prelude Therapeutics (NASDAQ:PRLD) Shares Up 9.3%Time to Buy? - MarketBeat

Aug 20, 2026
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Aug 20, 2026

12 Health Care Stocks Moving In Thursday's Intraday Session - Benzinga

Aug 20, 2026
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Aug 19, 2026

Prelude Therapeutics Number of Employees 2026 | Employee Count & Headcount Data - Revelio Labs

Aug 19, 2026
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Aug 13, 2026

Prelude Therapeutics Hits New 52-Week High of $5.91, Reflecting Strong Growth - MarketsMojo

Aug 13, 2026
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Aug 12, 2026

Prelude Therapeutics Incorporated reports results for the quarter ended June 30Earnings Summary - TradingView

Aug 12, 2026
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Aug 12, 2026

Prelude Therapeutics Incorporated (NASDAQ:PRLD) Receives Consensus Recommendation of "Hold" from Analysts - MarketBeat

Aug 12, 2026
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Aug 12, 2026

We're Not Worried About Prelude Therapeutics' (NASDAQ:PRLD) Cash Burn - Moomoo

Aug 12, 2026
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Aug 12, 2026

Prelude Therapeutics (PRLD) Stock Rallies As Losses Ease But Milestones Remain Unclear - webull.com

Aug 12, 2026
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Aug 11, 2026

Prelude Therapeutics (NASDAQ:PRLD) Releases Quarterly Earnings Results, Beats Estimates By $0.03 EPS - MarketBeat

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Reports Q2 2026 Earnings Featuring First Revenue and Reduced Losses - Kalkine Media

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Reports $13.9 Million Q2 Net Loss - Quiver Quantitative

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics reports Q2 2026 results: $5.7M revenue, $13.9M net loss, $155.2M cash - TradingView

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics reports Q2 EPS (14c), consensus (19c) - TipRanks

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update - The Manila Times

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Q2 revenue beats analyst expectations, net loss narrows - TradingView

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics 2Q Loss/Shr 14c >PRLD - Moomoo

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Reports $13.9 Million Q2 Net Loss | PRLD Stock News - Quiver Quantitative

Aug 11, 2026
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Aug 11, 2026

Prelude Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update - Yahoo Finance

Aug 11, 2026
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Aug 06, 2026

Prelude Therapeutics (PRLD) Expected to Post Earnings on Thursday - MarketBeat

Aug 06, 2026
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Aug 04, 2026

Pathos AI pads pipeline with $2.2B Alphamab deal, AZ pact - Fierce Biotech

Aug 04, 2026

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prelude Therapeutics Inc Stock (PRLD) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Apr 21 '26
Buy
4.44
2,815,315
12,499,999
11,808,945
$6.58
price down icon 4.22%
$9.94
price down icon 3.21%
$5.53
price down icon 3.66%
$11.27
price down icon 6.16%
$18.60
price down icon 1.74%
WVE WVE
$3.13
price down icon 1.88%
Cap:     |  Volume (24h):