3.79
price up icon2.43%   0.09
after-market After Hours: 3.80 0.010 +0.26%
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Prime Medicine Inc stock is traded at $3.79, with a volume of 2.17M. It is up +2.43% in the last 24 hours and up +3.84% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$3.70
Open:
$3.76
24h Volume:
2.17M
Relative Volume:
0.79
Market Cap:
$684.29M
Revenue:
$4.63M
Net Income/Loss:
$-201.14M
P/E Ratio:
-2.7582
EPS:
-1.3741
Net Cash Flow:
$-167.10M
1W Performance:
+7.06%
1M Performance:
+3.84%
6M Performance:
-40.50%
1Y Performance:
+187.12%
1-Day Range:
Value
$3.655
$3.84
1-Week Range:
Value
$3.27
$3.87
52-Week Range:
Value
$1.11
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-02-27
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
3.79 668.04M 4.63M -201.14M -167.10M -1.3741
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.70 113.01B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
753.93 79.87B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
840.87 51.51B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
333.39 45.29B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
319.94 34.41B 5.36B 287.73M 924.18M 2.5229

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
Apr 13, 2026

Short Covering: Whats the fair value of Prime Medicine Inc stockTrade Performance Summary & High Accuracy Swing Trade Signals - baoquankhu1.vn

Apr 13, 2026
pulisher
Apr 11, 2026

Prime Medicine (NASDAQ:PRME) Downgraded to "Strong Sell" Rating by Wall Street Zen - MarketBeat

Apr 11, 2026
pulisher
Apr 10, 2026

Top Prime Medicine (PRME) Competitors 2026 - MarketBeat

Apr 10, 2026
pulisher
Apr 10, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 6.4%Here's What Happened - MarketBeat

Apr 10, 2026
pulisher
Apr 09, 2026

Prime Medicine slips after Q4 updates - MSN

Apr 09, 2026
pulisher
Apr 08, 2026

PRME PE Ratio & Valuation, Is PRME Overvalued - Intellectia AI

Apr 08, 2026
pulisher
Apr 08, 2026

Stock Market Recap: Whats the fair value of Prime Medicine Inc stock2026 WrapUp & Community Trade Idea Sharing - baoquankhu1.vn

Apr 08, 2026
pulisher
Apr 07, 2026

Trend Review: Should I trade or invest in Prime Medicine Inc2026 Setups & Community Verified Swing Trade Signals - baoquankhu1.vn

Apr 07, 2026
pulisher
Mar 31, 2026

The $578 Billion Regenerative Medicine Market Has a Manufacturing Problem. One Company Just Solved the First Step - Benzinga

Mar 31, 2026
pulisher
Mar 31, 2026

Prime Medicine Inc. (PRME) Stock Price | Live Quotes & Charts | NASDAQ - StocksToTrade

Mar 31, 2026
pulisher
Mar 31, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Receives Consensus Rating of "Moderate Buy" from Brokerages - MarketBeat

Mar 31, 2026
pulisher
Mar 31, 2026

The $578 Billion Regenerative Medicine Market Has a Manufacturing Problem. One Company Just Solved the First Step - Finviz

Mar 31, 2026
pulisher
Mar 30, 2026

Bear Alert: Should I trade or invest in Prime Medicine Inc2026 Bull vs Bear & Low Volatility Stock Recommendations - baoquankhu1.vn

Mar 30, 2026
pulisher
Mar 30, 2026

S P Trends: Will Prime Medicine Inc stock hit new highs in YEARMarket Performance Summary & Precise Buy Zone Identification - baoquankhu1.vn

Mar 30, 2026
pulisher
Mar 27, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Down 7.3%What's Next? - MarketBeat

Mar 27, 2026
pulisher
Mar 26, 2026

Prime Medicine (PRME) focuses on liver franchise with $191.4M cash runway - MSN

Mar 26, 2026
pulisher
Mar 26, 2026

Prime Medicine (NASDAQ:PRME) Trading Up 5.6%Time to Buy? - MarketBeat

Mar 26, 2026
pulisher
Mar 24, 2026

Support Test: Does Prime Medicine Inc have declining or rising EPSWeekly Risk Summary & Consistent Growth Equity Picks - baoquankhu1.vn

Mar 24, 2026
pulisher
Mar 21, 2026

Aug PostEarnings: Is Prime Medicine Inc a strong growth stock2026 Trade Ideas & Fast Entry and Exit Trade Plans - baoquankhu1.vn

Mar 21, 2026
pulisher
Mar 18, 2026

Prime Medicine, Inc. (PRME) reports Q4 loss, misses revenue estimates - MSN

Mar 18, 2026
pulisher
Mar 18, 2026

Prime Medicine stock plummets amid restructuring and leadership changes - MSN

Mar 18, 2026
pulisher
Mar 17, 2026

Hedge Fund Bets: Whats the fair value of Prime Medicine Inc stock2026 Institutional & Risk Managed Investment Entry Signals - baoquankhu1.vn

Mar 17, 2026
pulisher
Mar 16, 2026

Farallon Capital Management LLC Buys 4,000,000 Shares of Prime Medicine, Inc. $PRME - MarketBeat

Mar 16, 2026
pulisher
Mar 15, 2026

Casdin Capital LLC Acquires 1,600,000 Shares of Prime Medicine, Inc. $PRME - MarketBeat

Mar 15, 2026
pulisher
Mar 12, 2026

Aug Weekly: Is Prime Medicine Inc backed by strong institutional buyingMarket Sentiment Review & Reliable Entry Point Alerts - baoquankhu1.vn

Mar 12, 2026
pulisher
Mar 12, 2026

Oppenheimer Initiates Coverage on PRME with "Outperform" Rating - GuruFocus

Mar 12, 2026
pulisher
Mar 12, 2026

Prime Medicine (NASDAQ:PRME) Shares Gap UpHere's Why - MarketBeat

Mar 12, 2026
pulisher
Mar 12, 2026

Prime Medicine (NYSE:PRME) Shares Gap UpShould You Buy? - MarketBeat

Mar 12, 2026
pulisher
Mar 12, 2026

Prime Medicine (NYSE:PRME) Earns Outperform Rating from Analysts at Oppenheimer - MarketBeat

Mar 12, 2026
pulisher
Mar 11, 2026

Prime Medicine, Inc. (PRME) Reports Q1 Loss, Misses Revenue Estimates - MSN

Mar 11, 2026
pulisher
Mar 11, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 6.3%Here's What Happened - MarketBeat

Mar 11, 2026
pulisher
Mar 11, 2026

Prime Medicine (NYSE:PRME) Shares Down 6.9%Here's What Happened - MarketBeat

Mar 11, 2026
pulisher
Mar 09, 2026

PRME Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Mar 09, 2026
pulisher
Mar 09, 2026

LifeSci Capital initiates Prime Medicine (PRME), highlights one-and-done potential in liver and lung diseases - MSN

Mar 09, 2026
pulisher
Mar 08, 2026

Prime Medicine (PRME) Focuses on Liver Franchise With $191.4M Cash Runway - Finviz

Mar 08, 2026
pulisher
Mar 07, 2026

Will Prime Medicine Inc. stock outperform value stocksPrice Action & Technical Confirmation Alerts - Naître et grandir

Mar 07, 2026
pulisher
Mar 07, 2026

Will Prime Medicine Inc. stock benefit from upcoming earnings reportsJuly 2025 Update & Growth Focused Entry Reports - Naître et grandir

Mar 07, 2026
pulisher
Mar 07, 2026

10 Best New Penny Stocks to Buy - Insider Monkey

Mar 07, 2026
pulisher
Mar 06, 2026

Guidance Update: Will Prime Medicine Inc stock hit new highs in YEARPortfolio Profit Report & Free Reliable Trade Execution Plans - baoquankhu1.vn

Mar 06, 2026
pulisher
Mar 06, 2026

HC Wainwright Predicts Stronger Earnings for Prime Medicine - MarketBeat

Mar 06, 2026
pulisher
Mar 06, 2026

Prime Medicine, Inc. (NYSE:PRME) Receives Consensus Rating of "Moderate Buy" from Analysts - MarketBeat

Mar 06, 2026
pulisher
Mar 05, 2026

Prime Medicine, Inc. Experiences Revision in Stock Evaluation Amid Mixed Performance Indicators - Markets Mojo

Mar 05, 2026
pulisher
Mar 05, 2026

Lifesci Capital Predicts Prime Medicine FY2025 Earnings - MarketBeat

Mar 05, 2026
pulisher
Mar 05, 2026

Prime Medicine, Inc. $PRME Shares Acquired by ARK Investment Management LLC - MarketBeat

Mar 05, 2026
pulisher
Mar 05, 2026

Prime Medicine, Inc. $PRME Stock Position Increased by Amova Asset Management Americas Inc. - MarketBeat

Mar 05, 2026
pulisher
Mar 05, 2026

[EFFECT] Prime Medicine, Inc. SEC Filing - Stock Titan

Mar 05, 2026
pulisher
Mar 04, 2026

Citizens reiterates Prime Medicine stock rating on PM359 pathway - Investing.com Australia

Mar 04, 2026
pulisher
Mar 04, 2026

Citizens reiterates Prime Medicine stock rating on PM359 pathway By Investing.com - Investing.com Canada

Mar 04, 2026
pulisher
Mar 04, 2026

Prime Medicine (NASDAQ:PRME) Upgraded by Lifesci Capital to "Strong-Buy" Rating - MarketBeat

Mar 04, 2026
pulisher
Mar 04, 2026

Prime Medicine unveils full year 2025 financial results and business update as progress advances - Traders Union

Mar 04, 2026
pulisher
Mar 03, 2026

Prime Medicine (PRME) Quarterly Loss Near US$50 Million Reinforces Bearish Community Narratives - simplywall.st

Mar 03, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prime Medicine Inc Stock (PRME) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
NELSEN ROBERT
Director
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners XII, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners X, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
Liu David R.
10% Owner
Jun 30 '25
Buy
2.52
21,000
52,830
20,240,945
Liu David R.
10% Owner
Jun 23 '25
Buy
2.16
21,000
45,402
20,219,945
Liu David R.
10% Owner
Jun 16 '25
Buy
1.49
21,000
31,196
20,198,945
Liu David R.
10% Owner
Jun 11 '25
Buy
1.60
21,000
33,590
20,177,945
Brudnick Richard
Chief Business Officer
May 20 '25
Buy
1.19
20,000
23,790
20,000
LEE ANN L.
Chief Technical Officer
May 21 '25
Buy
1.13
100,000
113,000
100,000
Reine Allan
Chief Executive Officer
May 21 '25
Buy
1.18
125,000
147,150
125,000
$54.26
price up icon 2.69%
$48.70
price down icon 0.25%
$99.47
price up icon 1.08%
$152.54
price up icon 3.76%
$146.74
price down icon 4.34%
ONC ONC
$319.94
price up icon 3.21%
Cap:     |  Volume (24h):