3.99
price up icon3.10%   0.12
after-market After Hours: 3.91 -0.08 -2.01%
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Prime Medicine Inc stock is traded at $3.99, with a volume of 4.45M. It is up +3.10% in the last 24 hours and up +30.39% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$3.87
Open:
$3.83
24h Volume:
4.45M
Relative Volume:
1.68
Market Cap:
$720.66M
Revenue:
$4.63M
Net Income/Loss:
$-201.14M
P/E Ratio:
-2.9037
EPS:
-1.3741
Net Cash Flow:
$-167.10M
1W Performance:
+7.26%
1M Performance:
+30.39%
6M Performance:
+7.84%
1Y Performance:
+28.30%
1-Day Range:
Value
$3.6595
$4.01
1-Week Range:
Value
$3.61
$4.32
52-Week Range:
Value
$2.67
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-08-06
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
3.99 666.48M 4.63M -201.14M -167.10M -1.3741
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
529.59 126.07B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
649.81 65.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
916.80 57.70B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
313.04 40.19B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
189.99 39.82B 742.00K -1.37B -1.07B -7.0731

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
Jun 30, 2026

Enterprise value to revenue forward of Prime Medicine, Inc. – NASDAQ:PRME - TradingView

Jun 30, 2026
pulisher
Jun 29, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates but Stock Gains on Pipeline ProgressEarnings Decline Risk - dars.gov.et

Jun 29, 2026
pulisher
Jun 29, 2026

Prime Medicine, Inc.(NasdaqGM: PRME) added to Russell 2500 Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Price to book forward of Prime Medicine, Inc. – NASDAQ:PRME - TradingView

Jun 29, 2026
pulisher
Jun 29, 2026

This Caseys Analyst Turns Bullish; Here Are Top 3 Upgrades For Monday - Benzinga

Jun 29, 2026
pulisher
Jun 29, 2026

Prime Medicine, Inc.(NasdaqGM:PRME) added to Russell Microcap Growth Benchmark Index - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

H.C. Wainwright upgrades Prime Medicine stock rating to buy - Investing.com

Jun 29, 2026
pulisher
Jun 29, 2026

Prime Medicine, Inc.(NasdaqGM: PRME) added to Russell 2000 Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Prime Medicine, Inc.(NasdaqGM: PRME) added to Russell 3000E Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 28, 2026

Prime Medicine, Inc.(NasdaqGM:PRME) added to Russell Small Cap Comp Growth Benchmark - marketscreener.com

Jun 28, 2026
pulisher
Jun 26, 2026

Prime Medicine, Inc. Actuals & Estimates (NASDAQ:PRME) - TradingView

Jun 26, 2026
pulisher
Jun 26, 2026

PRME Forecast — Price Target — Prediction for 2027 - TradingView

Jun 26, 2026
pulisher
Jun 25, 2026

Prime Medicine Inc (PRME) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 25, 2026
pulisher
Jun 25, 2026

Prime Medicine (PRME) Short Interest & Short Float | Updated Jun 2026 - MarketBeat

Jun 25, 2026
pulisher
Jun 23, 2026

LifeSci Capital Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $6 - Moomoo

Jun 23, 2026
pulisher
Jun 22, 2026

Prime Medicine Says PM359 Granted US FDA Regenerative Medicine Advanced Therapy Designation - Moomoo

Jun 22, 2026
pulisher
Jun 22, 2026

Prime Medicine Receives U.S. FDA Regenerative Medicine Advanced Therapy (RMAT) Designation for PM359 for the Treatment of Chronic Granulomatous Disease (CGD) - marketscreener.com

Jun 22, 2026
pulisher
Jun 22, 2026

Prime Medicine Receives U.S. FDA Regenerative Medicine - GlobeNewswire

Jun 22, 2026
pulisher
Jun 22, 2026

Citizens reiterates Prime Medicine stock rating on gene therapy focus By Investing.com - Investing.com South Africa

Jun 22, 2026
pulisher
Jun 22, 2026

Citizens reiterates Prime Medicine stock rating on gene therapy focus - Investing.com

Jun 22, 2026
pulisher
Jun 22, 2026

Prime Medicine’s CGD therapy gets FDA RMAT, speeding review - Stock Titan

Jun 22, 2026
pulisher
Jun 19, 2026

Prime Medicine, Inc. (PRME) reports Q1 loss, misses revenue estimates - MSN

Jun 19, 2026
pulisher
Jun 19, 2026

Analysts Are Bullish on These Healthcare Stocks: Prime Medicine, Inc. (PRME), Ocular Therapeutix (OCUL) - The Globe and Mail

Jun 19, 2026
pulisher
Jun 19, 2026

Prime Medicine’s PM-577a cleared for clinic for Wilson’s disease - BioWorld News

Jun 19, 2026
pulisher
Jun 19, 2026

Prime Medicine receives clearance for first in vivo gene therapy trial - Investing.com Canada

Jun 19, 2026
pulisher
Jun 18, 2026

Prime Medicine receives clearance for first in vivo gene therapy trial By Investing.com - Investing.com India

Jun 18, 2026
pulisher
Jun 18, 2026

Prime Medicine Announces New Zealand Clearance of Clinical - GlobeNewswire

Jun 18, 2026
pulisher
Jun 18, 2026

Prime Medicine Inc (PRME) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 18, 2026
pulisher
Jun 17, 2026

Prime Medicine Inc (PRME) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
pulisher
Jun 17, 2026

Ocular Therapeutix vs Prime Medicine: Two Paths in Medical Innovation - HarianBasis.co

Jun 17, 2026
pulisher
Jun 17, 2026

Prime Medicine Inc (PRME) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 17, 2026
pulisher
Jun 17, 2026

Prime Medicine Inc (PRME) Institutional Confidence - TradingKey

Jun 17, 2026
pulisher
Jun 17, 2026

Prime Medicine Inc (PRME) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
pulisher
Jun 16, 2026

Prime Medicine Inc (PRME) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 16, 2026
pulisher
Jun 16, 2026

Prime Medicine Inc (PRME) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 16, 2026
pulisher
Jun 16, 2026

Prime Medicine Inc (PRME) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 16, 2026
pulisher
Jun 15, 2026

Ocular Therapeutix vs. Prime Medicine: A 2026 Analysis of Medical Innovation StocksNews and Statistics - IndexBox

Jun 15, 2026
pulisher
Jun 15, 2026

Ocular Therapeutix vs. Prime Medicine: Which Healthcare Stock Is a Better Buy in 2026? - The Motley Fool

Jun 15, 2026
pulisher
Jun 13, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates Amid Ongoing Development ProgramsEPS Guidance Update - newsline.com

Jun 13, 2026
pulisher
Jun 13, 2026

Prime Medicine's Prime Editing Is Worth The Risk (NASDAQ:PRME) - Seeking Alpha

Jun 13, 2026
pulisher
Jun 12, 2026

Prime Drink Group announces private placement up to C$2.2M By Investing.com - Investing.com Australia

Jun 12, 2026
pulisher
Jun 12, 2026

Prime Drink Group announces private placement up to C$2.2M - Investing.com UK

Jun 12, 2026
pulisher
Jun 12, 2026

Prime Medicine (PRME) Holds Steady Near Support as Gene Editing Stock Seeks DirectionBlue Chip Entry Points - newsline.com

Jun 12, 2026
pulisher
Jun 11, 2026

PRME Price Today: Prime Medicine, Inc. Stock Price, Quote & Chart | MEXC - MEXC

Jun 11, 2026
pulisher
Jun 10, 2026

Transcript : Prime Medicine, Inc. Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026, Jun-10-2026 10 - marketscreener.com

Jun 10, 2026
pulisher
Jun 09, 2026

Prime Medicine Stockholders Reaffirm Board and Auditor Choices - The Globe and Mail

Jun 09, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) awards director David Schenkein 75,000 stock options - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director receives 75,000 options at $3.06 - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director and 10% owner receives 75,000-share option grant - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director receives 75,000-share stock option grant - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) awards director 75,000 stock options at $3.06 - Stock Titan

Jun 08, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prime Medicine Inc Stock (PRME) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
NELSEN ROBERT
Director
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners XII, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners X, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
$111.54
price down icon 0.05%
$56.92
price down icon 1.47%
$35.39
price up icon 0.74%
ONC ONC
$309.46
price up icon 3.97%
$81.80
price up icon 2.56%
$189.99
price up icon 0.40%
Cap:     |  Volume (24h):