2.90
price up icon4.50%   0.125
pre-market  Pre-market:  2.92   0.02   +0.69%
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Prime Medicine Inc stock is traded at $2.90, with a volume of 2.91M. It is up +4.50% in the last 24 hours and down -1.02% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$2.775
Open:
$2.92
24h Volume:
2.91M
Relative Volume:
1.21
Market Cap:
$523.79M
Revenue:
$4.63M
Net Income/Loss:
$-201.14M
P/E Ratio:
-2.1105
EPS:
-1.3741
Net Cash Flow:
$-167.10M
1W Performance:
-2.03%
1M Performance:
-1.02%
6M Performance:
-28.22%
1Y Performance:
+98.63%
1-Day Range:
Value
$2.84
$3.06
1-Week Range:
Value
$2.67
$3.06
52-Week Range:
Value
$1.4135
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-08-06
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
2.90 523.79M 4.63M -201.14M -167.10M -1.3741
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
450.46 114.33B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
614.98 64.47B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
884.20 54.99B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
287.80 38.42B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
160.06 34.03B 742.00K -1.37B -1.07B -7.0731

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
Jun 15, 2026

Ocular Therapeutix vs. Prime Medicine: A 2026 Analysis of Medical Innovation StocksNews and Statistics - IndexBox

Jun 15, 2026
pulisher
Jun 15, 2026

Ocular Therapeutix vs. Prime Medicine: Which Healthcare Stock Is a Better Buy in 2026? - The Motley Fool

Jun 15, 2026
pulisher
Jun 13, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates Amid Ongoing Development ProgramsEPS Guidance Update - newsline.com

Jun 13, 2026
pulisher
Jun 13, 2026

Prime Medicine's Prime Editing Is Worth The Risk (NASDAQ:PRME) - Seeking Alpha

Jun 13, 2026
pulisher
Jun 12, 2026

Prime Drink Group announces private placement up to C$2.2M By Investing.com - Investing.com Australia

Jun 12, 2026
pulisher
Jun 12, 2026

Prime Drink Group announces private placement up to C$2.2M - Investing.com UK

Jun 12, 2026
pulisher
Jun 12, 2026

Prime Medicine (PRME) Holds Steady Near Support as Gene Editing Stock Seeks DirectionBlue Chip Entry Points - newsline.com

Jun 12, 2026
pulisher
Jun 11, 2026

PRME Price Today: Prime Medicine, Inc. Stock Price, Quote & Chart | MEXC - MEXC

Jun 11, 2026
pulisher
Jun 10, 2026

Transcript : Prime Medicine, Inc. Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026, Jun-10-2026 10 - marketscreener.com

Jun 10, 2026
pulisher
Jun 08, 2026

Prime Medicine Stockholders Reaffirm Board and Auditor Choices - TipRanks

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) awards director David Schenkein 75,000 stock options - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director receives 75,000 options at $3.06 - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director and 10% owner receives 75,000-share option grant - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director receives 75,000-share stock option grant - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) awards director 75,000 stock options at $3.06 - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) director receives 75,000 stock options at $3.06 - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

[Form 4] Prime Medicine, Inc. Insider Trading Activity - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Prime Medicine (PRME) shareholders elect Class I directors and ratify PwC as 2026 auditor - Stock Titan

Jun 08, 2026
pulisher
Jun 08, 2026

Is Prime Medicine (NASDAQ:PRME) In A Good Position To Deliver On Growth Plans? - Moomoo

Jun 08, 2026
pulisher
Jun 07, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates as Pre-Commercial Biotech Continues R&D FocusROA Comparison - newsline.com

Jun 07, 2026
pulisher
Jun 05, 2026

PRME News | PRIME MEDICINE INC (NASDAQ:PRME) - ChartMill

Jun 05, 2026
pulisher
Jun 04, 2026

We're Keeping An Eye On Prime Medicine's (NASDAQ:PRME) Cash Burn Rate - Yahoo Finance

Jun 04, 2026
pulisher
Jun 04, 2026

Prime Medicine, Inc. (PRME) Reports Q4 Loss, Misses Revenue Estimates - Eastern Progress

Jun 04, 2026
pulisher
Jun 03, 2026

Prime Medicine CEO to speak at Goldman Sachs Healthcare Conference on June 10, 2026 - Pluang

Jun 03, 2026
pulisher
Jun 03, 2026

Prime Medicine to Present at Goldman Sachs 47th Annual Global Healthcare Conference - The Manila Times

Jun 03, 2026
pulisher
May 30, 2026

Prime Medicine Inc. Gains 4.41% as Gene Editing Stock Tests Key ResistanceMax Pain Level - The Legal Advocate

May 30, 2026
pulisher
May 30, 2026

PRME Q1 2026 Earnings: Wider-than-Expected Loss but Positive Stock Reaction Amid Pipeline ProgressDiluted EPS Report - newsline.com

May 30, 2026
pulisher
May 29, 2026

Prime Medicine (PRME) Gains Ground as Shares Approach Key ResistanceGap Up Stocks - newsline.com

May 29, 2026
pulisher
May 28, 2026

Prime Medicine to Present at Jefferies Global Healthcare Conference - The Manila Times

May 28, 2026
pulisher
May 28, 2026

Prime Medicine CEO to speak at Jefferies Healthcare Conference on June 4, 2026 - Pluang

May 28, 2026
pulisher
May 27, 2026

Prime Medicine (PRME) Surges Over 11% as Gene Editing Stock Finds Support Near $3.13Factor Valuation - The Legal Advocate

May 27, 2026
pulisher
May 26, 2026

PRME - Finviz

May 26, 2026
pulisher
May 25, 2026

Prime Medicine Inc. (PRME) Q1 2026 Earnings: Wider-than-Expected Loss Highlights Pre-Revenue Development PhaseEPS Estimate Trend - The Legal Advocate

May 25, 2026
pulisher
May 23, 2026

PRME Q1 2026 Earnings: EPS Worse Than Expected as Pre-Revenue Biotech Advances PipelinePro Level Trade Signals - Newser

May 23, 2026
pulisher
May 22, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates as Pre-Revenue Biotech Focuses on Pipeline Progress - Newser

May 22, 2026
pulisher
May 19, 2026

Prime Medicine (PRME) Q1 2026 Disappoints — EPS $-0.28 Below $-0.26 ViewsEarnings Turnaround - Newser

May 19, 2026
pulisher
May 19, 2026

Prime Medicine slips after Q4 updates - MSN

May 19, 2026
pulisher
May 13, 2026

Prime Medicine (PRME) Reports Q1 EPS - Yahoo Finance

May 13, 2026
pulisher
May 12, 2026

10 Best Penny Stocks to Buy Before They Explode - Insider Monkey

May 12, 2026
pulisher
May 12, 2026

Oppenheimer Maintains Prime Medicine(PRME.US) With Buy Rating, Announces Target Price $11 - Moomoo

May 12, 2026
pulisher
May 11, 2026

TradingKey - TradingKey

May 11, 2026
pulisher
May 11, 2026

Prime Medicine, Inc. (PRME) reports Q1 loss, misses revenue estimates - MSN

May 11, 2026
pulisher
May 11, 2026

Number of shareholders of Prime Medicine, Inc. – NASDAQ:PRME - TradingView

May 11, 2026
pulisher
May 09, 2026

LifeSci Capital Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $6 - Moomoo

May 09, 2026
pulisher
May 08, 2026

PRME Prime Medicine revenue jumps 55% YoY in Q1; shares rally 3% on growth momentum.Management Guidance - newser.com

May 08, 2026
pulisher
May 08, 2026

JonesTrading Initiates Prime Medicine(PRME.US) With Buy Rating, Announces Target Price $5 - Moomoo

May 08, 2026
pulisher
May 08, 2026

H.C. Wainwright Maintains Prime Medicine(PRME.US) With Hold Rating - Moomoo

May 08, 2026
pulisher
May 08, 2026

The opportunity most miss about Prime Medicine (PRME) (-8.65%) 2026-05-08Value Factor - newsline.com

May 08, 2026
pulisher
May 07, 2026

Prime Medicine Inc reports results for the quarter ended March 31Earnings Summary - TradingView

May 07, 2026
pulisher
May 07, 2026

Prime Medicine (NASDAQ:PRME) Q1 Results Show Revenue Miss and Narrower Loss as Key Pipeline Milestones Loom - ChartMill

May 07, 2026
pulisher
May 07, 2026

PRIME MEDICINE ($PRME) Releases Q1 2026 Earnings - Quiver Quantitative

May 07, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prime Medicine Inc Stock (PRME) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
NELSEN ROBERT
Director
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners XII, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners X, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
Liu David R.
10% Owner
Jun 30 '25
Buy
2.52
21,000
52,830
20,240,945
Liu David R.
10% Owner
Jun 23 '25
Buy
2.16
21,000
45,402
20,219,945
$97.46
price down icon 0.40%
$30.03
price down icon 0.03%
$90.80
price up icon 0.29%
$54.27
price down icon 1.09%
ONC ONC
$268.20
price up icon 1.41%
$160.06
price up icon 4.02%
Cap:     |  Volume (24h):