2.90
price down icon5.54%   -0.17
after-market After Hours: 2.95 0.05 +1.72%
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Prime Medicine Inc stock is traded at $2.90, with a volume of 7.08M. It is down -5.54% in the last 24 hours and down -21.83% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$3.07
Open:
$3.42
24h Volume:
7.08M
Relative Volume:
2.13
Market Cap:
$525.99M
Revenue:
$4.03M
Net Income/Loss:
$-198.37M
P/E Ratio:
-2.3108
EPS:
-1.255
Net Cash Flow:
$-158.74M
1W Performance:
-7.05%
1M Performance:
-21.83%
6M Performance:
-20.11%
1Y Performance:
-44.44%
1-Day Range:
Value
$2.875
$3.44
1-Week Range:
Value
$2.875
$3.565
52-Week Range:
Value
$2.67
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-11-06
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, MRNA, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
2.90 525.99M 4.03M -198.37M -158.74M -1.255
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
526.19 133.37B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
788.04 81.13B 14.92B 4.42B 3.79B 41.04
MRNA icon
MRNA
Moderna Inc
198.88 79.40B 2.23B -3.19B -1.60B -8.1462
ARGX icon
ARGX
Argen X Se Adr
959.49 60.03B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
204.97 43.93B 742.00K -1.37B -1.07B -7.0731

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
03:44 AM

PRME Surges 15% After Winning Arbitration Against Beam — Clears Path To Human Trials For Its Gene-Editing Drug - Stocktwits

03:44 AM
pulisher
Sep 25, 2026

PRME Stock Dips As Prime Medicine Faces Steep Losses - StocksToTrade

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine Stock Slips As Traders Digest Weak Margins - StocksToTrade

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine: A Buy Due To BLA Filing H1 '27 And In Vivo Therapy Development (PRME) - Seeking Alpha

Sep 25, 2026
pulisher
Sep 25, 2026

First Trust Heitman Glbl Prm Rl Estt ETF (PRME) stock price, news, quote and history - Yahoo Finance UK

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine Gets FDA Green Light for Gene Editing Study - Benzinga

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine, Inc. (PRME) Stock Price, News, Quote & History - Yahoo! Finance Canada

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine's PM647 Clears Key Regulatory Hurdle, Oppenheimer Says - marketscreener.com

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine (NASDAQ:PRME) Shares Gap UpWhat's Next? - MarketBeat

Sep 25, 2026
pulisher
Sep 25, 2026

FDA Clears Prime Medicine to Start Gene Editing Trial After Beam Dispute - GenomeWeb

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine, Inc. (PRME) stock price, news, quote and history - Yahoo Finance Singapore

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine’s PM-647 gains IND approval for AATD - BioWorld News

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine (NASDAQ:PRME) Stock Keeps Buy Rating at Chardan Capital - MarketBeat

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine stock holds at outperform on FDA IND clearance By Investing.com - Investing.com Australia

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine stock holds at outperform on FDA IND clearance - Investing.com

Sep 25, 2026
pulisher
Sep 25, 2026

Prime Medicine stock jumps 8% after FDA clears PM647 trial - TradingView

Sep 25, 2026
pulisher
Sep 25, 2026

Chardan Capital Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $7 - Moomoo

Sep 25, 2026
pulisher
Sep 24, 2026

Stocks to Watch: Akamai, Scholastic, Prime Medicine - Moomoo

Sep 24, 2026
pulisher
Sep 24, 2026

Prime Medicine Announces U.S. FDA Clearance Of Investigational New Drug Application For Pm647 In Alpha-1 Antitrypsin Deficiency - TradingView

Sep 24, 2026
pulisher
Sep 24, 2026

Why is Prime Medicine stock surging today? By Investing.com - Investing.com Canada

Sep 24, 2026
pulisher
Sep 24, 2026

12 Health Care Stocks Moving In Thursday's After-Market Session - Benzinga

Sep 24, 2026
pulisher
Sep 24, 2026

Prime Medicine stock surges on FDA IND clearance - finance.yahoo.com

Sep 24, 2026
pulisher
Sep 24, 2026

Prime Medicine receives FDA clearance for AATD gene therapy - Investing.com

Sep 24, 2026
pulisher
Sep 24, 2026

FDA clears testing of a genetic treatment aimed at a variant carried by about 100,000 people in the U.S. - Stock Titan

Sep 24, 2026
pulisher
Sep 24, 2026

Prime Medicine (PRME) Short Interest & Short Float | Updated Sep 2026 - MarketBeat

Sep 24, 2026
pulisher
Sep 23, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Down 7.5%Should You Sell? - MarketBeat

Sep 23, 2026
pulisher
Sep 23, 2026

Can Prime Medicine (NASDAQ:PRME) Afford To Invest In Growth? - Moomoo

Sep 23, 2026
pulisher
Sep 22, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat

Sep 22, 2026
pulisher
Sep 17, 2026

Prime Medicine (NASDAQ:PRME): What's Behind Its Sudden Share Price Jump? - Kalkine Media

Sep 17, 2026
pulisher
Sep 17, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 11.8%Should You Buy? - MarketBeat

Sep 17, 2026
pulisher
Sep 15, 2026

PRME: Prime Editing advances versatile gene therapies with strong clinical and financial momentum - TradingView

Sep 15, 2026
pulisher
Sep 15, 2026

Prime Medicine at H.C. Wainwright conference: platform gains focus By Investing.com - Investing.com Canada

Sep 15, 2026
pulisher
Sep 12, 2026

Prime Medicine (NASDAQ:PRME) Rating Increased to Hold at Wall Street Zen - MarketBeat

Sep 12, 2026
pulisher
Sep 11, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Down 4.3%Here's What Happened - MarketBeat

Sep 11, 2026
pulisher
Sep 03, 2026

A gene-editing company sets three September conference appearances - Stock Titan

Sep 03, 2026
pulisher
Sep 03, 2026

Prime Medicine to Participate in Upcoming Investor Conferences - Yahoo Finance

Sep 03, 2026
pulisher
Sep 02, 2026

BlackRock Inc. Acquires Shares of 9,602,041 Prime Medicine, Inc. $PRME - MarketBeat

Sep 02, 2026
pulisher
Aug 28, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Given Average Recommendation of "Moderate Buy" by Brokerages - MarketBeat

Aug 28, 2026
pulisher
Aug 27, 2026

Prime Medicine (NASDAQ:PRME) Upgraded to Strong-Buy at Chardan Capital - marketbeat.com

Aug 27, 2026
pulisher
Aug 26, 2026

ADAR1 Capital Management LLC Makes New Investment in Prime Medicine, Inc. $PRME - MarketBeat

Aug 26, 2026
pulisher
Aug 25, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 6.3%Here's What Happened - MarketBeat

Aug 25, 2026
pulisher
Aug 20, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 6.9%Should You Sell? - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

Prime Medicine (NASDAQ:PRME) Rating Increased to Strong-Buy at BMO Capital Markets - MarketBeat

Aug 20, 2026
pulisher
Aug 19, 2026

Prime Medicine Company Profile & Introduction - Moomoo

Aug 19, 2026
pulisher
Aug 19, 2026

PRIME MEDICINE, INC. : BMO INITIATES COVERAGE WITH OUTPERFORM RATING; PRICE TARGET $9 - Bitget

Aug 19, 2026
pulisher
Aug 19, 2026

PRME Initiated Coverage by BMO Capital -- Rating Set to Outperfo - GuruFocus

Aug 19, 2026
pulisher
Aug 19, 2026

Prime (PRME) Results Breakdown: The Available Earnings Metric Delivers a Beat for the Current Session; Investor Response: Shares Fall 3.79% on the DayConsensus Beat Rate - vinanet.vn

Aug 19, 2026
pulisher
Aug 19, 2026

BMO initiates Prime Medicine stock with outperform rating By Investing.com - Investing.com Canada

Aug 19, 2026
pulisher
Aug 18, 2026

Alphabet Inc. Takes Position in Prime Medicine, Inc. $PRME - MarketBeat

Aug 18, 2026
pulisher
Aug 18, 2026

Prime (PRME) Earnings Recap: EPS Beats Its Estimate; Trading-Day Reaction: Shares Finish 3.47% Down in the Current UpdateRetail Earnings Report - careplusvn.com

Aug 18, 2026
pulisher
Aug 17, 2026

Prime Medicine Number of Employees 2026 | Employee Count & Headcount Data - Revelio Labs

Aug 17, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$117.83
price down icon 3.06%
$35.80
price down icon 0.91%
$58.21
price down icon 0.14%
$255.96
price up icon 2.55%
ONC ONC
$360.85
price up icon 0.24%
$204.97
price up icon 2.56%
Cap:     |  Volume (24h):