28.82
price up icon2.47%   0.695
 
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Septerna Inc stock is traded at $28.82, with a volume of 200.30K. It is up +2.47% in the last 24 hours and up +15.62% over the past month. Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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Previous Close:
$28.13
Open:
$28.6
24h Volume:
200.30K
Relative Volume:
0.67
Market Cap:
$1.29B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
-3.88%
1M Performance:
+15.62%
6M Performance:
+104.14%
1Y Performance:
+367.94%
1-Day Range:
Value
$27.50
$29.02
1-Week Range:
Value
$26.58
$30.70
52-Week Range:
Value
$4.66
$32.63

Septerna Inc Stock (SEPN) Company Profile

Name
Name
Septerna Inc
Name
Phone
650-338-3533
Name
Address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO
Name
Employee
75
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SEPN's Discussions on Twitter

Compare SEPN vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SEPN
Septerna Inc
28.82 1.26B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
477.89 120.48B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
787.50 81.05B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
749.56 46.33B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
327.30 42.26B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
299.02 32.87B 5.36B 287.73M 924.18M 2.5229

Septerna Inc Stock (SEPN) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-19-25 Initiated Raymond James Strong Buy
Dec-15-25 Initiated Truist Buy
Nov-14-25 Upgrade Wells Fargo Equal Weight → Overweight
Jun-23-25 Initiated H.C. Wainwright Buy
Feb-18-25 Downgrade Wells Fargo Overweight → Equal Weight
Nov-19-24 Initiated Cantor Fitzgerald Overweight
Nov-19-24 Initiated JP Morgan Overweight
Nov-19-24 Initiated TD Cowen Buy
Nov-19-24 Initiated Wells Fargo Overweight
View All

Septerna Inc Stock (SEPN) Latest News

pulisher
Mar 03, 2026

SEPN: SEP-631 advances to phase II in CSU after robust phase I results; SEP-479 enters clinical trials - TradingView

Mar 03, 2026
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Mar 03, 2026

SEPN: SEP-631 and SEP-479 advance with strong data, phase 2 and 1 trials planned, and pipeline growth - TradingView

Mar 03, 2026
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Mar 03, 2026

Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN), Payoneer (PAYO) and Porch Group (PRCH) - The Globe and Mail

Mar 03, 2026
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Mar 03, 2026

A Look At Septerna (SEPN) Valuation After Recent Share Price Momentum And GPCR Pipeline Reassessment - Sahm

Mar 03, 2026
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Mar 03, 2026

Septerna (SEPN) Receives Overweight Rating and Target Price Hike by Wells Fargo | SEPN Stock News - GuruFocus

Mar 03, 2026
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Mar 02, 2026

[144] Septerna, Inc. SEC Filing - Stock Titan

Mar 02, 2026
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Mar 02, 2026

Septerna (NASDAQ:SEPN) Price Target Raised to $40.00 at HC Wainwright - MarketBeat

Mar 02, 2026
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Mar 02, 2026

Septerna Stock: A Deep Dive Into Analyst Perspectives (5 Ratings) - Benzinga

Mar 02, 2026
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Mar 02, 2026

Septerna Advances SEP-631 After Positive Phase 1 Results - TipRanks

Mar 02, 2026
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Mar 02, 2026

SEPN: SEP-631 showed strong Phase 1 efficacy and safety, advancing to Phase 2 for urticaria in 2026 - TradingView

Mar 02, 2026
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Mar 02, 2026

Septerna reports positive Phase 1 SEP-631 data; plans Phase 2b CSU study in 2H 2026 - TradingView

Mar 02, 2026
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Mar 02, 2026

Positive SEP-631 trial data drives Phase 2 plan at Septerna (NASDAQ: SEPN) - Stock Titan

Mar 02, 2026
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Mar 01, 2026

Septerna’s SEP-631 shows positive Phase 1 trial results - Investing.com Australia

Mar 01, 2026
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Mar 01, 2026

Septerna Announces Positive Phase 1 Data for SEP-631, an Oral MRGPRX2 NAM for the Treatment of Mast Cell-Driven Diseases, and Outlines Initial Phase 2 Development Strategy - Bitget

Mar 01, 2026
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Mar 01, 2026

Septerna says SEP-631 well-tolerated with adverse event profile comparable to placebo - marketscreener.com

Mar 01, 2026
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Mar 01, 2026

Septerna Says SEP-631 Well-Tolerated With Adverse Event Profile Comparable To Placebo - TradingView

Mar 01, 2026
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Mar 01, 2026

Septerna pill blocked induced skin wheals at low doses in Phase 1 test - Stock Titan

Mar 01, 2026
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Mar 01, 2026

Sentiment Watch: Is Septerna Inc part of any ETFBear Alert & Free Community Consensus Stock Picks - baoquankhu1.vn

Mar 01, 2026
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Mar 01, 2026

Why Septerna (SEPN) Is Up 6.4% After Surging GPCR Pipeline-Driven Revenue GrowthAnd What's Next - simplywall.st

Mar 01, 2026
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Feb 28, 2026

Septerna, Inc. (NASDAQ:SEPN) Given Consensus Recommendation of "Moderate Buy" by Analysts - MarketBeat

Feb 28, 2026
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Feb 27, 2026

Septerna, Inc. (SEPN) Stock Analysis: Unleashing a 12,113% Revenue Growth Amidst Biotech Innovations - DirectorsTalk Interviews

Feb 27, 2026
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Feb 26, 2026

Zacks Research Upgrades Septerna (NASDAQ:SEPN) to Hold - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Aug Breakouts: Does Septerna Inc have a sustainable dividendMarket Trend Report & Weekly Consistent Profit Watchlists - baoquankhu1.vn

Feb 26, 2026
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Feb 25, 2026

Septerna stock reaches all-time high at 31.39 USD By Investing.com - Investing.com Australia

Feb 25, 2026
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Feb 25, 2026

Septerna (NASDAQ:SEPN) Reaches New 12-Month HighStill a Buy? - MarketBeat

Feb 25, 2026
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Feb 25, 2026

SEP-631 Phase 1 Readout: The Catalyst Set To Drive Septerna In 2026 (NASDAQ:SEPN) - Seeking Alpha

Feb 25, 2026
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Feb 25, 2026

Septerna stock reaches all-time high at 31.39 USD - Investing.com

Feb 25, 2026
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Feb 24, 2026

Will Septerna Inc outperform the market in YEAR2025 Trade Ideas & Free Fast Gain Swing Trade Alerts - baoquankhu1.vn

Feb 24, 2026
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Feb 24, 2026

Septerna to Present at TD Cowen 46th Annual Health Care Conference - Bitget

Feb 24, 2026
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Feb 24, 2026

Biotech Septerna to webcast TD Cowen health talk on March 3 - Stock Titan

Feb 24, 2026
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Feb 22, 2026

SEPNSepterna, Inc. Latest Stock News & Market Updates - Stock Titan

Feb 22, 2026
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Feb 21, 2026

Septerna president Bhatt sells $115,860 in shares By Investing.com - Investing.com South Africa

Feb 21, 2026
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Feb 21, 2026

Septerna, Inc. (SEPN) Stock Analysis: A Biotech Powerhouse With A 25% Upside Potential - DirectorsTalk Interviews

Feb 21, 2026
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Feb 20, 2026

Septerna president Bhatt sells $115,860 in shares - Investing.com Nigeria

Feb 20, 2026
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Feb 20, 2026

Insider Selling: Septerna (NASDAQ:SEPN) COO Sells 4,000 Shares of Stock - MarketBeat

Feb 20, 2026
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Feb 20, 2026

Will Septerna Inc. announce a stock split2025 Technical Overview & Accurate Intraday Trading Signals - mfd.ru

Feb 20, 2026
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Feb 20, 2026

Septerna (NASDAQ:SEPN) Trading Down 5.9%Here's What Happened - MarketBeat

Feb 20, 2026
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Feb 19, 2026

Will Septerna Inc. stock return to pre crisis levelsMarket Growth Report & Accurate Entry and Exit Point Alerts - mfd.ru

Feb 19, 2026
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Feb 18, 2026

Insiders See US$934.3k Investment In Septerna Jump Last Week - 富途牛牛

Feb 18, 2026
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Feb 18, 2026

Septerna (NASDAQ:SEPN) Hits New 1-Year HighWhat's Next? - MarketBeat

Feb 18, 2026
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Feb 18, 2026

Septerna Inc stock hits all-time high at 30.51 USD By Investing.com - Investing.com Canada

Feb 18, 2026
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Feb 18, 2026

Septerna Inc stock hits all-time high at 30.51 USD - Investing.com India

Feb 18, 2026
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Feb 17, 2026

Septerna (NASDAQ:SEPN) Shares Up 9.4%Here's What Happened - MarketBeat

Feb 17, 2026
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Feb 17, 2026

Risk Analysis: How volatile is Septerna Inc stockPortfolio Growth Summary & Risk Controlled Swing Trade Alerts - baoquankhu1.vn

Feb 17, 2026
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Feb 16, 2026

Investment Recap: Is Septerna Inc forming a bullish divergenceNew Guidance & Consistent Growth Stock Picks - baoquankhu1.vn

Feb 16, 2026
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Feb 14, 2026

Published on: 2026-02-21 01:46:34 - mfd.ru

Feb 14, 2026
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Feb 13, 2026

Septerna, Inc. (SEPN) Stock Analysis: Biotechnology Pioneer With 31.43% Upside Potential - DirectorsTalk Interviews

Feb 13, 2026
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Feb 12, 2026

Loss Report: Does Septerna Inc have a sustainable dividendMarket Risk Analysis & Safe Entry Point Alerts - baoquankhu1.vn

Feb 12, 2026
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Feb 11, 2026

How Early SEP-631 Data at AAAAI 2026 Will Impact Septerna (SEPN) Investors - simplywall.st

Feb 11, 2026
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Feb 11, 2026

Septerna Reports Inducement Grant under Nasdaq Listing Rule 5635(4) - marketscreener.com

Feb 11, 2026
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Feb 11, 2026

Septerna to present phase 1 data for SEP-631 at AAAAI meeting - Investing.com Canada

Feb 11, 2026

Septerna Inc Stock (SEPN) Financials Data

There is no financial data for Septerna Inc (SEPN). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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$47.43
price down icon 0.11%
$29.52
price up icon 6.00%
$57.80
price up icon 15.99%
$103.80
price up icon 3.02%
$149.88
price up icon 1.96%
biotechnology ONC
$299.02
price up icon 0.67%
Cap:     |  Volume (24h):