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36.75
0.14%
-0.05
Septerna Inc stock is traded at $36.75, with a volume of 199.66K.
It is down -0.14% in the last 24 hours and down -5.72% over the past month.
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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Previous Close:
$36.80
Open:
$36.57
24h Volume:
199.66K
Relative Volume:
0.46
Market Cap:
$1.72B
Revenue:
$45.95M
Net Income/Loss:
$-48.88M
P/E Ratio:
-33.02
EPS:
-1.1129
Net Cash Flow:
$109.67M
1W Performance:
-5.55%
1M Performance:
-5.72%
6M Performance:
+27.49%
1Y Performance:
+160.27%
1-Day Range:
$36.57
$37.59
1-Week Range:
$36.46
$39.10
52-Week Range:
$13.67
$51.10
Septerna Inc Stock (SEPN) Company Profile
Name
Septerna Inc
Sector
Industry
Phone
650-338-3533
Address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO
Compare SEPN vs VRTX, REGN, ARGX, MRNA, RVMD
| Stocks | Price | Market Cap | Revenue | Net Income | Cash Flow | EPS |
|---|---|---|---|---|---|---|
SEPN
Septerna Inc
|
36.75 | 1.90B | 45.95M | -48.88M | 109.67M | -1.1129 |
VRTX
Vertex Pharmaceuticals Inc
|
546.12 | 136.93B | 12.34B | 4.34B | 3.71B | 16.87 |
REGN
Regeneron Pharmaceuticals Inc
|
827.72 | 85.11B | 14.92B | 4.42B | 3.79B | 41.04 |
ARGX
Argen X Se Adr
|
1,033.15 | 64.95B | 4.16B | 1.29B | 734.26M | 19.58 |
MRNA
Moderna Inc
|
145.55 | 53.23B | 2.23B | -3.19B | -1.60B | -8.1462 |
RVMD
Revolution Medicines Inc
|
210.02 | 45.38B | 742.00K | -1.37B | -1.07B | -7.0731 |
Septerna Inc Stock (SEPN) Upgrades & Downgrades
| Date | Action | Analyst | Rating Change |
|---|---|---|---|
| Dec-19-25 | Initiated | Raymond James | Strong Buy |
| Dec-15-25 | Initiated | Truist | Buy |
| Nov-14-25 | Upgrade | Wells Fargo | Equal Weight → Overweight |
| Jun-23-25 | Initiated | H.C. Wainwright | Buy |
| Feb-18-25 | Downgrade | Wells Fargo | Overweight → Equal Weight |
| Nov-19-24 | Initiated | Cantor Fitzgerald | Overweight |
| Nov-19-24 | Initiated | JP Morgan | Overweight |
| Nov-19-24 | Initiated | TD Cowen | Buy |
| Nov-19-24 | Initiated | Wells Fargo | Overweight |
View All
Septerna Inc Stock (SEPN) Latest News
Driehaus Capital Management Expands Septerna Inc (SEPN) Stake in Second Quarter - GuruFocus
Septerna (NASDAQ:SEPN) Stock Price Down 8%Time to Sell? - MarketBeat
SEPN Maintained by JP Morgan -- Price Target Raised to $48 - GuruFocus
Septerna (NASDAQ:SEPN) Price Target Raised to $48.00 - MarketBeat
SEPTERNA, INC. : JP MORGAN RAISES TARGET PRICE TO $48 FROM $38 - Bitget
4,211,659 Shares in Septerna, Inc. $SEPN Acquired by Trv Gp Vi LLC - MarketBeat
Trv Gp V LLC Takes Position in Septerna, Inc. $SEPN - MarketBeat
Septerna, Inc. (SEPN) Receives a Rating Update from a Top Analyst - The Globe and Mail
37,700 Shares in Septerna, Inc. $SEPN Purchased by Renaissance Technologies LLC - MarketBeat
Ra Capital Management sells $63.45m in Septerna stock By Investing.com - Investing.com Australia
Ra Capital Management sells $63.45m in Septerna stock - Investing.com
Septerna(SEPN.US) 10% Shareholder Sells US$7.4 Million in Common Stock - Moomoo
Third Rock Ventures V, L.P. director sells $7.4m Septerna shares - Investing.com South Africa
RA Capital Management Offloads 1.49 Million Septerna Shares at $42.50 Each - Kalkine Media
Septerna (SEPN): RA Capital funds disclose sale of 1.49M common shares - Stock Titan
Form 4: Third Rock Ventures reports acquisition/exercise transactions in SEPN - Stock Titan
RA Capital group (SEPN) discloses 11.8% Septerna stake and major block sales - Stock Titan
HC Wainwright Predicts Septerna's Q3 Earnings (NASDAQ:SEPN) - MarketBeat
Driehaus Capital Management (SEPN) discloses 4.43M-share Septerna stake in 13G/A - Stock Titan
Septerna (NASDAQ:SEPN) COO Elizabeth Bhatt Sells 25,000 Shares of Stock - MarketBeat
Septerna president & COO Elizabeth Bhatt disposes of $1.1m in stock - Investing.com Nigeria
Septerna (SEPN) President & COO exercises 25,000 options and sells shares under 10b5-1 plan - Stock Titan
Septerna (NASDAQ:SEPN) Trading Down 6.1%Here's Why - MarketBeat
JonesTrading Forecasts Strong Price Appreciation for Septerna (NASDAQ:SEPN) Stock - MarketBeat
Wall Street Analysts Are Bullish on Top NA Picks - The Globe and Mail
SEPTERNA, INC. : TRUIST SECURITIES RAISES TARGET PRICE TO $59 FROM $43 - Bitget
Stifel Maintains Septerna(SEPN.US) With Buy Rating, Raises Target Price to $49 - Moomoo
Septerna, Inc. SEC Filing (Aug 12, 2026) - Stock Titan
SEPN (SEPN) plans NASDAQ sale of 746,500 shares worth $35.97M - Stock Titan
Does Septerna (SEPN) Pair Narrowing Losses With A Cash Runway That Truly Supports Its Pipeline Strategy? - simplywall.st
Septerna Inc stock hits all-time high at 50.0 USD By Investing.com - Investing.com Canada
Septerna (NASDAQ:SEPN) Sees Unusually-High Trading Volume on Analyst Upgrade - MarketBeat
Septerna Inc stock hits all-time high at 50.0 USD - Investing.com
SEPN Maintained by Wells Fargo -- Price Target Raised to $50 - GuruFocus
H.C. Wainwright raises Septerna stock price target to $60 on SEP-479 progress - Investing.com
A Quick Look at Today's Ratings for Septerna(SEPN.US), With a Forecast Between $49 to $60 - Moomoo
Septerna (NASDAQ:SEPN) Price Target Raised to $50.00 at Wells Fargo & Company - MarketBeat
Septerna (NASDAQ:SEPN) Price Target Raised to $60.00 - MarketBeat
SEPN Maintained by HC Wainwright & Co. -- Price Target Raised to $60 - GuruFocus
Septerna Shares (SEPN) Surge 23% Following Positive SEP-479 Signal, Exceeding Analyst Predictions - TechStock²
Stifel raises Septerna stock price target to $49 on SEP-479 outlook - Investing.com UK
Septerna, Inc. Stock 12‑Month Price Target Raised to $47, Implies 21% Upside - TradingView
Seer (SEPN) insiders plan sale of 29,000 shares after option exercise - Stock Titan
SEPN Maintains by Guggenheim -- Price Target Raised to $51.00 - GuruFocus
Raymond James Maintains Septerna(SEPN.US) With Buy Rating, Cuts Target Price to $49 - Moomoo
Septerna (NASDAQ:SEPN) Stock Price Up 9% Following Earnings Beat - MarketBeat
Guggenheim raises Septerna stock price target to $51 on pipeline progress - Investing.com South Africa
Stifel raises Septerna stock price target to $49 on SEP-479 outlook By Investing.com - Investing.com India
Septerna Inc Stock (SEPN) Financials Data
Revenue
Net Income
Cash Flow
EPS
Septerna Inc Stock (SEPN) Insider Trading
| Insider Trading | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total |
|---|---|---|---|---|---|---|---|
| Bhatt Elizabeth | President and COO |
Aug 11 '26 |
Option Exercise |
5.79 |
25,000 |
144,658 |
199,209 |
| Bhatt Elizabeth | President and COO |
Aug 11 '26 |
Sale |
44.00 |
25,000 |
1,100,000 |
174,209 |
0.86%
0.31%
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