102.13
price up icon2.14%   2.14
after-market After Hours: 102.89 0.76 +0.74%
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Spyre Therapeutics Inc Stock (SYRE) Price History

The historical daily chart and data for Spyre Therapeutics Inc stock (SYRE), show that the latest closing stock price as of July 24, 2026, is $102.13.
  • Spyre Therapeutics Inc all-time high stock price is $105.09, occurred on July 14, 2026.
  • The lowest Spyre Therapeutics Inc stock price recorded was $10.42 on November 28, 2023. Since then, Spyre Therapeutics Inc's stock price has risen over 880.13% to $102.13 now.
  • The 52-week high stock price for SYRE is $105.09, representing a 2.90% increase from the current share price, occurred on July 14, 2026.
  • The 52-week low stock price for SYRE is $14.51, indicating a -85.80% decrease from the current share price, occurred on September 22, 2025.
The table below shows more information about SYRE historical price data:
Date High Low High - Low Volume % Change
Jul 24, 2026 $103.6 $98.79 $4.78 809,672.0 +2.14%
Jul 23, 2026 $100.3 $97.00 $3.35 634,817.0 +0.83%
Jul 22, 2026 $102.4 $99.06 $3.33 596,126.0 -3.44%
Jul 21, 2026 $103.3 $98.50 $4.81 776,508.0 +5.52%
Jul 20, 2026 $102.9 $97.28 $5.64 750,165.0 -2.89%
Jul 17, 2026 $101.4 $92.37 $8.99 1,091,385.0 +6.49%
Jul 16, 2026 $103.3 $93.37 $9.95 1,369,657.0 -7.79%
Jul 15, 2026 $102.6 $95.14 $7.44 1,520,300.0 +3.15%
Jul 14, 2026 $105.1 $94.95 $10.14 2,710,733.0 +5.57%
Jul 13, 2026 $96.81 $92.67 $4.14 997,626.0 -4.10%
Jul 10, 2026 $99.34 $94.13 $5.21 778,881.0 -1.02%
Jul 09, 2026 $99.00 $96.11 $2.89 1,329,047.0 +3.51%
Jul 08, 2026 $95.59 $90.64 $4.95 1,237,683.0 +1.24%
Jul 07, 2026 $95.16 $86.60 $8.55 1,305,750.0 +6.19%
Jul 06, 2026 $91.89 $86.61 $5.28 1,369,208.0 +2.44%
Jul 02, 2026 $89.69 $85.17 $4.52 965,972.0 -2.54%
Jul 01, 2026 $89.02 $86.41 $2.61 1,682,136.0 +0.12%
Jun 30, 2026 $91.95 $88.60 $3.36 1,451,591.0 -1.53%
Jun 29, 2026 $90.90 $84.81 $6.09 1,993,464.0 +2.58%
Jun 26, 2026 $91.00 $85.97 $5.03 3,954,404.0 -0.88%
Jun 25, 2026 $89.67 $84.96 $4.71 2,108,937.0 +2.82%

Spyre Therapeutics Inc Stock (SYRE) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spyre Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SYRE shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spyre Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spyre Therapeutics Inc Stock (SYRE) Price History 2026

Month High Low High - Low Volume % Change
Jul, 2026 $105.1 $85.17 $19.92 20,735,338.0 +15.04%
Jun, 2026 $102.1 $68.50 $33.56 36,899,922.0 +20.79%
May, 2026 $78.80 $64.67 $14.13 20,278,975.0 -1.28%
Apr, 2026 $75.00 $46.27 $28.73 29,467,600.0 +47.60%
Mar, 2026 $51.06 $38.36 $12.70 18,228,687.0 +17.28%
Feb, 2026 $45.76 $30.92 $14.84 14,598,463.0 +34.49%
Jan, 2026 $35.06 $28.00 $7.06 12,290,223.0 -2.38%

Spyre Therapeutics Inc Stock (SYRE) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $35.31 $28.16 $7.15 17,921,513.0 +6.27%
Nov, 2025 $30.21 $21.14 $9.07 11,809,120.0 +22.65%
Oct, 2025 $25.05 $15.86 $9.20 28,914,443.0 +45.94%
Sep, 2025 $17.58 $14.51 $3.07 13,700,922.0 +1.64%
Aug, 2025 $17.80 $14.72 $3.08 9,673,575.0 -2.83%
Jul, 2025 $18.30 $14.00 $4.30 12,397,594.0 +13.36%
Jun, 2025 $19.20 $13.93 $5.27 12,638,190.0 -2.03%
May, 2025 $15.77 $12.29 $3.48 10,197,865.0 +0.33%
Apr, 2025 $16.12 $10.91 $5.21 17,251,629.0 -5.61%
Mar, 2025 $21.03 $16.13 $4.90 13,287,855.0 -18.10%
Feb, 2025 $24.83 $18.26 $6.57 10,925,495.0 -14.31%
Jan, 2025 $26.01 $20.25 $5.76 11,749,605.0 -1.25%

Spyre Therapeutics Inc Stock (SYRE) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $29.06 $22.37 $6.69 9,847,302.0 -20.72%
Nov, 2024 $40.26 $25.74 $14.52 14,404,771.0 -12.60%
Oct, 2024 $36.60 $26.28 $10.32 8,567,734.0 +10.61%
Sep, 2024 $31.89 $26.52 $5.37 12,800,810.0 +2.30%
Aug, 2024 $29.00 $23.31 $5.69 8,943,039.0 +4.55%
Jul, 2024 $32.41 $23.00 $9.41 11,316,523.0 +16.97%
Jun, 2024 $38.90 $22.19 $16.71 20,949,923.0 -32.73%
May, 2024 $40.49 $31.39 $9.11 6,780,000.0 +5.81%
Apr, 2024 $40.84 $31.27 $9.57 6,849,784.0 -12.92%
Mar, 2024 $47.97 $28.48 $19.49 14,248,629.0 +38.23%
Feb, 2024 $28.80 $20.07 $8.73 9,579,014.0 +5.91%
Jan, 2024 $28.66 $18.54 $10.12 6,339,820.0 +20.40%
$106.92
price down icon 0.46%
$117.67
price up icon 0.84%
$35.01
price down icon 0.26%
$58.83
price down icon 0.32%
ONC ONC
$325.90
price down icon 0.27%
$271.77
price up icon 1.13%
Cap:     |  Volume (24h):