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Spyre Therapeutics Inc Stock (SYRE) Price History

The historical daily chart and data for Spyre Therapeutics Inc stock (SYRE), show that the latest closing stock price as of September 12, 2025, is $15.65.
  • Spyre Therapeutics Inc all-time high stock price is $47.97, occurred on March 18, 2024.
  • The lowest Spyre Therapeutics Inc stock price recorded was $10.42 on November 28, 2023. Since then, Spyre Therapeutics Inc's stock price has risen over 50.19% to $15.65 now.
  • The 52-week high stock price for SYRE is $40.26, representing a 157.25% increase from the current share price, occurred on November 12, 2024.
  • The 52-week low stock price for SYRE is $10.91, indicating a -30.29% decrease from the current share price, occurred on April 09, 2025.
The table below shows more information about SYRE historical price data:
Date High Low High - Low Volume % Change
Sep 12, 2025 $16.11 $15.64 $0.47 431,142.0 -3.40%
Sep 11, 2025 $16.59 $16.10 $0.495 737,665.0 +0.12%
Sep 10, 2025 $16.63 $15.80 $0.83 305,408.0 -3.35%
Sep 09, 2025 $17.11 $16.30 $0.81 251,677.0 +0.66%
Sep 08, 2025 $17.13 $16.52 $0.61 284,358.0 -2.18%
Sep 05, 2025 $17.58 $16.86 $0.72 339,702.0 +0.06%
Sep 04, 2025 $17.33 $16.23 $1.10 672,557.0 +1.07%
Sep 03, 2025 $17.44 $16.32 $1.12 275,093.0 +1.08%
Sep 02, 2025 $17.00 $16.12 $0.88 431,689.0 +0.85%
Aug 29, 2025 $16.75 $16.27 $0.475 351,933.0 -1.38%
Aug 28, 2025 $17.39 $16.64 $0.745 298,692.0 -2.45%
Aug 27, 2025 $17.34 $16.89 $0.455 329,482.0 +0.47%
Aug 26, 2025 $17.12 $16.38 $0.74 514,487.0 +2.90%
Aug 25, 2025 $17.46 $16.46 $1.00 331,318.0 -4.60%
Aug 22, 2025 $17.80 $16.77 $1.03 805,613.0 +3.58%
Aug 21, 2025 $16.91 $15.91 $0.995 688,310.0 +2.63%
Aug 20, 2025 $16.53 $15.73 $0.80 601,792.0 +1.49%
Aug 19, 2025 $16.82 $15.91 $0.91 530,058.0 -4.90%
Aug 18, 2025 $17.40 $16.69 $0.71 393,997.0 -0.06%
Aug 15, 2025 $17.42 $16.86 $0.56 536,949.0 +0.53%
Aug 14, 2025 $17.25 $16.77 $0.485 270,930.0 -3.10%

Spyre Therapeutics Inc Stock (SYRE) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spyre Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SYRE shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spyre Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spyre Therapeutics Inc Stock (SYRE) Price History 2025

Month High Low High - Low Volume % Change
Sep, 2025 $17.58 $15.64 $1.94 4,160,433.0 -5.09%
Aug, 2025 $17.80 $14.72 $3.08 9,673,575.0 -2.83%
Jul, 2025 $18.30 $14.00 $4.30 12,397,594.0 +13.36%
Jun, 2025 $19.20 $13.93 $5.27 12,638,190.0 -2.03%
May, 2025 $15.77 $12.29 $3.48 10,197,865.0 +0.33%
Apr, 2025 $16.12 $10.91 $5.21 17,251,629.0 -5.61%
Mar, 2025 $21.03 $16.13 $4.90 13,287,855.0 -18.10%
Feb, 2025 $24.83 $18.26 $6.57 10,925,495.0 -14.31%
Jan, 2025 $26.01 $20.25 $5.76 11,749,605.0 -1.25%

Spyre Therapeutics Inc Stock (SYRE) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $29.06 $22.37 $6.69 9,847,302.0 -20.72%
Nov, 2024 $40.26 $25.74 $14.52 14,404,771.0 -12.60%
Oct, 2024 $36.60 $26.28 $10.32 8,567,734.0 +10.61%
Sep, 2024 $31.89 $26.52 $5.37 12,800,810.0 +2.30%
Aug, 2024 $29.00 $23.31 $5.69 8,943,039.0 +4.55%
Jul, 2024 $32.41 $23.00 $9.41 11,316,523.0 +16.97%
Jun, 2024 $38.90 $22.19 $16.71 20,949,923.0 -32.73%
May, 2024 $40.49 $31.39 $9.11 6,780,000.0 +5.81%
Apr, 2024 $40.84 $31.27 $9.57 6,849,784.0 -12.92%
Mar, 2024 $47.97 $28.48 $19.49 14,248,629.0 +38.23%
Feb, 2024 $28.80 $20.07 $8.73 9,579,014.0 +5.91%
Jan, 2024 $28.66 $18.54 $10.12 6,339,820.0 +20.40%

Spyre Therapeutics Inc Stock (SYRE) Price History 2023

Month High Low High - Low Volume % Change
Dec, 2023 $22.66 $14.22 $8.44 3,057,713.0 +15.33%
Nov, 2023 $19.60 $10.42 $9.18 339,919.0 +0.00%
$36.36
price down icon 0.93%
$83.10
price down icon 3.56%
$27.82
price down icon 2.76%
$96.74
price down icon 7.26%
$145.93
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biotechnology ONC
$324.34
price down icon 3.38%
Cap:     |  Volume (24h):