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80.10
1.87%
1.47
After Hours:
80.10
Spyre Therapeutics Inc Stock (SYRE) Price History
The historical daily chart and data for Spyre Therapeutics Inc stock (SYRE), show that the latest closing stock price as of October 15, 2026, is $80.10.
- Spyre Therapeutics Inc all-time high stock price is $110.17, occurred on August 19, 2026.
- The lowest Spyre Therapeutics Inc stock price recorded was $10.42 on November 28, 2023. Since then, Spyre Therapeutics Inc's stock price has risen over 668.71% to $80.10 now.
- The 52-week high stock price for SYRE is $110.17, representing a 37.55% increase from the current share price, occurred on August 19, 2026.
- The 52-week low stock price for SYRE is $21.01, indicating a -73.77% decrease from the current share price, occurred on October 15, 2025.
- The closing price of Spyre Therapeutics Inc (SYRE) stock in the beginning of 2025 was $23.85. The stock closed the year at $32.76, a gain of over 37.36% for the year.
The table below shows more information about SYRE historical price data:
Daily
Weekly
Monthly
7D
30D
60D
YTD
1Y
| Date | High | Low | High - Low | Volume | % Change |
|---|---|---|---|---|---|
| Oct 15, 2026 | $80.88 | $76.87 | $4.01 | 1,146,174.0 | +1.87% |
| Oct 14, 2026 | $82.45 | $77.95 | $4.50 | 1,624,639.0 | -2.26% |
| Oct 13, 2026 | $85.32 | $80.45 | $4.87 | 1,441,085.0 | -6.34% |
| Oct 12, 2026 | $86.62 | $84.21 | $2.41 | 873,909.0 | +0.25% |
| Oct 09, 2026 | $86.22 | $78.73 | $7.49 | 1,116,438.0 | +7.25% |
| Oct 08, 2026 | $80.91 | $77.05 | $3.86 | 2,326,679.0 | -1.18% |
| Oct 07, 2026 | $82.22 | $78.00 | $4.22 | 2,719,344.0 | +0.92% |
| Oct 06, 2026 | $92.08 | $79.36 | $12.72 | 4,252,338.0 | -13.60% |
| Oct 05, 2026 | $95.01 | $89.49 | $5.52 | 642,857.0 | -0.50% |
| Oct 02, 2026 | $95.27 | $90.48 | $4.79 | 1,235,019.0 | +3.63% |
| Oct 01, 2026 | $94.06 | $87.25 | $6.81 | 1,662,581.0 | +1.01% |
| Sep 30, 2026 | $95.08 | $88.00 | $7.08 | 2,096,144.0 | +5.09% |
| Sep 29, 2026 | $86.64 | $83.25 | $3.39 | 1,053,249.0 | -1.25% |
| Sep 28, 2026 | $87.12 | $84.00 | $3.12 | 1,045,536.0 | +0.12% |
| Sep 25, 2026 | $88.10 | $85.63 | $2.47 | 560,081.0 | -1.61% |
| Sep 24, 2026 | $87.46 | $82.93 | $4.53 | 1,729,571.0 | -1.22% |
| Sep 23, 2026 | $91.56 | $86.30 | $5.26 | 918,770.0 | -4.13% |
| Sep 22, 2026 | $93.58 | $89.90 | $3.68 | 1,223,437.0 | -0.07% |
| Sep 21, 2026 | $94.06 | $89.65 | $4.41 | 1,448,727.0 | +1.97% |
| Sep 18, 2026 | $93.34 | $89.85 | $3.49 | 3,357,063.0 | -2.62% |
| Sep 17, 2026 | $95.19 | $91.14 | $4.05 | 1,438,884.0 | +1.66% |
| Sep 16, 2026 | $93.06 | $90.48 | $2.58 | 1,257,627.0 | +0.24% |
| Sep 15, 2026 | $91.07 | $88.47 | $2.60 | 858,480.0 | +0.17% |
Spyre Therapeutics Inc Stock (SYRE) Year by Year Price History
In this detailed analysis, we present a comprehensive overview of the price movements of Spyre Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SYRE shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spyre Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.
Spyre Therapeutics Inc Stock (SYRE) Price History 2026
| Month | High | Low | High - Low | Volume | % Change |
|---|---|---|---|---|---|
| Oct, 2026 | $95.27 | $76.87 | $18.40 | 19,041,063.0 | -10.03% |
| Sep, 2026 | $95.19 | $82.93 | $12.26 | 26,705,303.0 | -0.34% |
| Aug, 2026 | $110.2 | $86.40 | $23.77 | 21,030,340.0 | -9.15% |
| Jul, 2026 | $105.1 | $85.17 | $19.92 | 24,788,615.0 | +10.76% |
| Jun, 2026 | $102.1 | $68.50 | $33.56 | 36,899,922.0 | +20.79% |
| May, 2026 | $78.80 | $64.67 | $14.13 | 20,278,975.0 | -1.28% |
| Apr, 2026 | $75.00 | $46.27 | $28.73 | 29,467,600.0 | +47.60% |
| Mar, 2026 | $51.06 | $38.36 | $12.70 | 18,228,687.0 | +17.28% |
| Feb, 2026 | $45.76 | $30.92 | $14.84 | 14,598,463.0 | +34.49% |
| Jan, 2026 | $35.06 | $28.00 | $7.06 | 12,290,223.0 | -2.38% |
Spyre Therapeutics Inc Stock (SYRE) Price History 2025
| Month | High | Low | High - Low | Volume | % Change |
|---|---|---|---|---|---|
| Dec, 2025 | $35.31 | $28.16 | $7.15 | 17,921,513.0 | +6.27% |
| Nov, 2025 | $30.21 | $21.14 | $9.07 | 11,809,120.0 | +22.65% |
| Oct, 2025 | $25.05 | $15.86 | $9.20 | 28,914,443.0 | +45.94% |
| Sep, 2025 | $17.58 | $14.51 | $3.07 | 13,700,922.0 | +1.64% |
| Aug, 2025 | $17.80 | $14.72 | $3.08 | 9,673,575.0 | -2.83% |
| Jul, 2025 | $18.30 | $14.00 | $4.30 | 12,397,594.0 | +13.36% |
| Jun, 2025 | $19.20 | $13.93 | $5.27 | 12,638,190.0 | -2.03% |
| May, 2025 | $15.77 | $12.29 | $3.48 | 10,197,865.0 | +0.33% |
| Apr, 2025 | $16.12 | $10.91 | $5.21 | 17,251,629.0 | -5.61% |
| Mar, 2025 | $21.03 | $16.13 | $4.90 | 13,287,855.0 | -18.10% |
| Feb, 2025 | $24.83 | $18.26 | $6.57 | 10,925,495.0 | -14.31% |
| Jan, 2025 | $26.01 | $20.25 | $5.76 | 11,749,605.0 | -1.25% |
Spyre Therapeutics Inc Stock (SYRE) Price History 2024
| Month | High | Low | High - Low | Volume | % Change |
|---|---|---|---|---|---|
| Dec, 2024 | $29.06 | $22.37 | $6.69 | 9,847,302.0 | -20.72% |
| Nov, 2024 | $40.26 | $25.74 | $14.52 | 14,404,771.0 | -12.60% |
| Oct, 2024 | $36.60 | $26.28 | $10.32 | 8,567,734.0 | +10.61% |
| Sep, 2024 | $31.89 | $26.52 | $5.37 | 12,800,810.0 | +2.30% |
| Aug, 2024 | $29.00 | $23.31 | $5.69 | 8,943,039.0 | +4.55% |
| Jul, 2024 | $32.41 | $23.00 | $9.41 | 11,316,523.0 | +16.97% |
| Jun, 2024 | $38.90 | $22.19 | $16.71 | 20,949,923.0 | -32.73% |
| May, 2024 | $40.49 | $31.39 | $9.11 | 6,780,000.0 | +5.81% |
| Apr, 2024 | $40.84 | $31.27 | $9.57 | 6,849,784.0 | -12.92% |
| Mar, 2024 | $47.97 | $28.48 | $19.49 | 14,248,629.0 | +38.23% |
| Feb, 2024 | $28.80 | $20.07 | $8.73 | 9,579,014.0 | +5.91% |
| Jan, 2024 | $28.66 | $18.54 | $10.12 | 6,339,820.0 | +20.40% |
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