16.97
price down icon1.85%   -0.32
after-market After Hours: 16.97
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Spyre Therapeutics Inc stock is traded at $16.97, with a volume of 599.80K. It is down -1.85% in the last 24 hours and up +13.36% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
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Previous Close:
$17.29
Open:
$17.1
24h Volume:
599.80K
Relative Volume:
1.08
Market Cap:
$1.02B
Revenue:
$1.23M
Net Income/Loss:
$-214.90M
P/E Ratio:
-4.1167
EPS:
-4.1222
Net Cash Flow:
$-151.25M
1W Performance:
-3.58%
1M Performance:
+13.36%
6M Performance:
-26.19%
1Y Performance:
-38.29%
1-Day Range:
Value
$16.57
$17.32
1-Week Range:
Value
$16.43
$18.00
52-Week Range:
Value
$10.91
$40.26

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
65
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
16.97 1.04B 1.23M -214.90M -151.25M -4.1222
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
456.87 120.48B 11.10B -988.90M -1.26B -3.92
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
545.46 59.88B 14.09B 4.50B 2.96B 39.28
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
392.24 44.31B 2.35B -269.70M -75.39M -2.09
Biotechnology icon
ARGX
Argen X Se Adr
670.33 36.65B 2.58B 1.06B -1.28B 16.33
Biotechnology icon
ONC
Beone Medicines Ltd Adr
301.13 32.46B 3.81B -644.79M -669.77M -6.24

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-08-25 Initiated Leerink Partners Outperform
Mar-18-25 Initiated Wolfe Research Outperform
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
View All

Spyre Therapeutics Inc Stock (SYRE) Latest News

pulisher
Jul 31, 2025

What moving averages say about Spyre Therapeutics Inc.Weekly Outlook for Short Term Investors - Newser

Jul 31, 2025
pulisher
Jul 31, 2025

Visual trend scoring systems applied to Spyre Therapeutics Inc.Algorithmic Forecast for Swing Trading Picks - Newser

Jul 31, 2025
pulisher
Jul 31, 2025

How strong is Spyre Therapeutics Inc. company’s balance sheetAI Powered Forecasts With Proven Results - jammulinksnews.com

Jul 31, 2025
pulisher
Jul 31, 2025

What catalysts could drive Spyre Therapeutics Inc. stock higher in 2025Free Stock Watchlist For Fast Growth - jammulinksnews.com

Jul 31, 2025
pulisher
Jul 31, 2025

Why Spyre Therapeutics Inc. stock attracts strong analyst attentionFree Access to Real-Time Trade Insights - Newser

Jul 31, 2025
pulisher
Jul 31, 2025

Will a bounce in Spyre Therapeutics Inc. offer an exitFree Community Shared Smart Money Signals - Newser

Jul 31, 2025
pulisher
Jul 31, 2025

What is the dividend policy of Spyre Therapeutics Inc. stockWealth Building Trend Scanner For 2025 - jammulinksnews.com

Jul 31, 2025
pulisher
Jul 31, 2025

Can momentum traders help lift Spyre Therapeutics Inc.Short-Term Bounce Forecast for Oversold Stocks - Newser

Jul 31, 2025
pulisher
Jul 31, 2025

How hedge fund analytics apply to Spyre Therapeutics Inc. stockAI Screener Based Stock Summary Report - Newser

Jul 31, 2025
pulisher
Jul 30, 2025

Spyre Therapeutics Inc. stock trend outlook and recovery pathBuy Signal System Based on Price Action - Newser

Jul 30, 2025
pulisher
Jul 30, 2025

How to track smart money flows in Spyre Therapeutics Inc.Buy Signal System Based on Price Action - Newser

Jul 30, 2025
pulisher
Jul 30, 2025

Identifying reversal signals in Spyre Therapeutics Inc.High Reward Investment Strategy for Beginners - Newser

Jul 30, 2025
pulisher
Jul 30, 2025

Moving Average Trends for Spyre Therapeutics Inc. Stock: What They IndicateDaily Market Momentum Summary and Strategy - Newser

Jul 30, 2025
pulisher
Jul 29, 2025

Sector ETF Data Correlates with Strength in Spyre Therapeutics Inc.Intraday Trend Analysis for Fast Gains Released - metal.it

Jul 29, 2025
pulisher
Jul 29, 2025

Trading Bots Trigger Alerts on Spyre Therapeutics Inc. ActivityCapital Growth With Controlled Risk Picks Suggested - metal.it

Jul 29, 2025
pulisher
Jul 29, 2025

How Resilient Is Spyre Therapeutics Inc. Stock During Economic DownturnsChart Breakout Buy Signal Detection Confirmed - metal.it

Jul 29, 2025
pulisher
Jul 29, 2025

Published on: 2025-07-29 08:11:08 - metal.it

Jul 29, 2025
pulisher
Jul 28, 2025

What are the technical indicators suggesting about Spyre Therapeutics Inc.Post Market Opportunities For Consistent Profits - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 28, 2025

How does Spyre Therapeutics Inc. compare to its industry peersSwing Trade Target Finder With Low Risk - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 28, 2025

Published on: 2025-07-28 20:59:32 - metal.it

Jul 28, 2025
pulisher
Jul 28, 2025

How volatile is Spyre Therapeutics Inc. stock compared to the marketBreakout Stocks Tracker With High Returns - jammulinksnews.com

Jul 28, 2025
pulisher
Jul 28, 2025

Published on: 2025-07-28 18:29:12 - metal.it

Jul 28, 2025
pulisher
Jul 28, 2025

Market reaction to Spyre Therapeutics Inc.’s recent newsConservative Asset Allocation Risk Analysis - Newser

Jul 28, 2025
pulisher
Jul 28, 2025

Victory Capital Management Inc. Sells 16,230 Shares of Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jul 28, 2025
pulisher
Jul 28, 2025

How Resilient Is Spyre Therapeutics Inc. Stock During Economic Downturns AI Trading Forecast Based on Big Data - Newser

Jul 28, 2025
pulisher
Jul 28, 2025

Market reaction to Spyre Therapeutics Inc.’s recent news Free Quick Gain Stock Watch With Indicators - metal.it

Jul 28, 2025
pulisher
Jul 27, 2025

What makes Spyre Therapeutics Inc. stock price move sharplyExplosive portfolio gains - jammulinksnews.com

Jul 27, 2025
pulisher
Jul 26, 2025

Will Spyre Therapeutics Inc. stock benefit from AI tech trendsTremendous financial leverage - jammulinksnews.com

Jul 26, 2025
pulisher
Jul 25, 2025

Is Spyre Therapeutics Inc. a good long term investmentHigh-impact stock picks - PrintWeekIndia

Jul 25, 2025
pulisher
Jul 24, 2025

Spyre Therapeutics Inc. Stock Analysis and ForecastFree Investment Risk Control - PrintWeekIndia

Jul 24, 2025
pulisher
Jul 24, 2025

What analysts say about Spyre Therapeutics Inc. stockOutstanding capital growth - Autocar Professional

Jul 24, 2025
pulisher
Jul 23, 2025

This Spyre Therapeutics Insider Reduced Their Stake By 55% - 富途牛牛

Jul 23, 2025
pulisher
Jul 23, 2025

What drives Spyre Therapeutics Inc. stock priceRapid capital growth - jammulinksnews.com

Jul 23, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$74.89
price down icon 3.43%
$36.80
price down icon 0.86%
$107.28
price up icon 2.00%
$26.37
price down icon 1.09%
$107.50
price down icon 2.32%
biotechnology ONC
$301.13
price up icon 0.40%
Cap:     |  Volume (24h):