18.07
price down icon4.56%   -0.8139
 
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Spyre Therapeutics Inc stock is traded at $18.07, with a volume of 50,668. It is down -4.56% in the last 24 hours and down -20.55% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
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Previous Close:
$18.88
Open:
$18.74
24h Volume:
50,668
Relative Volume:
0.09
Market Cap:
$1.12B
Revenue:
$1.23M
Net Income/Loss:
$-214.90M
P/E Ratio:
-4.3826
EPS:
-4.1222
Net Cash Flow:
$-151.25M
1W Performance:
-12.10%
1M Performance:
-20.55%
6M Performance:
-38.62%
1Y Performance:
-59.51%
1-Day Range:
Value
$18.01
$19.00
1-Week Range:
Value
$17.25
$21.03
52-Week Range:
Value
$17.25
$47.97

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
65
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
18.06 1.12B 1.23M -214.90M -151.25M -4.1222
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
498.17 130.96B 11.02B -535.60M -978.00M -2.20
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
678.01 75.53B 14.20B 4.41B 3.54B 38.28
Biotechnology icon
ARGX
Argen X Se Adr
577.05 35.07B 2.19B 833.04M -1.28B 12.71
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
240.79 31.72B 2.25B -278.16M -42.59M -2.17
Biotechnology icon
ONC
Beigene Ltd Adr
249.13 26.76B 3.32B -860.46M -1.04B -8.32

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
View All

Spyre Therapeutics Inc Stock (SYRE) Latest News

pulisher
Mar 08, 2025

Spyre Therapeutics Announces Grants of Inducement Awards - cnhinews.com

Mar 08, 2025
pulisher
Mar 07, 2025

Spyre Therapeutics Inc (SYRE) Announces Stock Option Grants to Non-Executive Employees - GuruFocus.com

Mar 07, 2025
pulisher
Mar 07, 2025

132,200 New Stock Options: Inside Spyre Therapeutics' Latest Employee Compensation Package - StockTitan

Mar 07, 2025
pulisher
Mar 06, 2025

Rhumbline Advisers Boosts Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Mar 06, 2025
pulisher
Mar 04, 2025

Spyre Therapeutics Faces Compliance Hurdles After Transition from Smaller Reporting Company Status - MSN

Mar 04, 2025
pulisher
Mar 04, 2025

Spyre Therapeutics Inc (SYRE) deserves closer scrutiny - US Post News

Mar 04, 2025
pulisher
Mar 04, 2025

Spyre Therapeutics: Targeting The Future Of IBD Treatment - Seeking Alpha

Mar 04, 2025
pulisher
Mar 02, 2025

Spyre Therapeutics (NASDAQ:SYRE) Trading 6.6% Higher After Strong Earnings - Defense World

Mar 02, 2025
pulisher
Feb 28, 2025

Spyre Therapeutics (NASDAQ:SYRE) Posts Earnings Results, Beats Expectations By $0.08 EPS - MarketBeat

Feb 28, 2025
pulisher
Feb 28, 2025

Buy Rating for Spyre Therapeutics Driven by Promising Drug Development and Strong Financial Position - TipRanks

Feb 28, 2025
pulisher
Feb 28, 2025

Spyre Therapeutics: Q4 Earnings Snapshot - The Pioneer

Feb 28, 2025
pulisher
Feb 28, 2025

Decoding Spyre Therapeutics Inc (SYRE): A Strategic SWOT Insight - GuruFocus.com

Feb 28, 2025
pulisher
Feb 28, 2025

Buy Rating for Spyre Therapeutics: Promising Pipeline and Strategic Advancements Drive Growth Potential - TipRanks

Feb 28, 2025
pulisher
Feb 27, 2025

Spyre Therapeutics Reports Strong Progress and Financial Stability - TipRanks

Feb 27, 2025
pulisher
Feb 27, 2025

Spyre Therapeutics reports Q4 EPS (81c), consensus (94c) - TipRanks

Feb 27, 2025
pulisher
Feb 27, 2025

Spyre Therapeutics Inc reports results for the quarter ended December 31Earnings Summary - TradingView

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update - PR Newswire

Feb 27, 2025
pulisher
Feb 27, 2025

Spyre Therapeutics (SYRE) Projected to Post Earnings on Thursday - Defense World

Feb 27, 2025
pulisher
Feb 26, 2025

Recent Insider Activity Could Benefit Spyre Therapeutics Inc (SYRE) - Knox Daily

Feb 26, 2025
pulisher
Feb 26, 2025

SYRE Stock Touches 52-Week Low at $20.24 Amid Market Challenges - Investing.com Australia

Feb 26, 2025
pulisher
Feb 25, 2025

Spyre Therapeutics (NASDAQ:SYRE) Hits New 1-Year LowTime to Sell? - MarketBeat

Feb 25, 2025
pulisher
Feb 25, 2025

Spyre Therapeutics to Participate in Upcoming March Investor Conferences - PR Newswire

Feb 25, 2025
pulisher
Feb 21, 2025

Spyre Therapeutics (NASDAQ:SYRE) Upgraded at The Goldman Sachs Group - Defense World

Feb 21, 2025
pulisher
Feb 20, 2025

Spyre Therapeutics, Inc. (SYRE) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Stockholders to Contact the Firm to Learn More About the Investigation - ACCESS Newswire

Feb 20, 2025
pulisher
Feb 19, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Rating of "Buy" by Analysts - MarketBeat

Feb 19, 2025
pulisher
Feb 19, 2025

Can This Novel Dual-Action IBD Treatment Transform Patient Care? New Data Reveals Promising Results - StockTitan

Feb 19, 2025
pulisher
Feb 17, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Recommendation of “Buy” by Analysts - Defense World

Feb 17, 2025
pulisher
Feb 15, 2025

1,955 Shares in Spyre Therapeutics, Inc. (NASDAQ:SYRE) Acquired by Mirae Asset Global Investments Co. Ltd. - Defense World

Feb 15, 2025
pulisher
Feb 12, 2025

InvestingPro Fair Value analysis proves accurate on Spyre Therapeutics call - MSN

Feb 12, 2025
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Feb 10, 2025

Can Spyre Therapeutics (SYRE) Climb 158.85% to Reach the Level Wall Street Analysts Expect? - MSN

Feb 10, 2025
pulisher
Feb 10, 2025

InvestingPro Fair Value analysis proves accurate on Spyre Therapeutics call By Investing.com - Investing.com

Feb 10, 2025
pulisher
Feb 07, 2025

Spyre (SYRE) Unveils Strategic Talent Retention Plan: 35K Options with 10-Year Window - StockTitan

Feb 07, 2025
pulisher
Feb 06, 2025

China Universal Asset Management Co. Ltd. Makes New Investment in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Feb 06, 2025
pulisher
Feb 05, 2025

SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Spyre Therapeutics, Inc.SYRE - cnhinews.com

Feb 05, 2025
pulisher
Feb 05, 2025

A company insider recently sold 6,700 shares of Spyre Therapeutics Inc [SYRE]. Should You also Consider to Sale? - Knox Daily

Feb 05, 2025
pulisher
Feb 05, 2025

Financial Analysis: Spyre Therapeutics Inc (SYRE)’s Ratios Unveil Key Insights - The Dwinnex

Feb 05, 2025
pulisher
Feb 04, 2025

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Spyre Therapeutics, Inc.SYRE - PR Newswire

Feb 04, 2025
pulisher
Feb 04, 2025

Spyre Therapeutics Inc (SYRE) stock analysis: A comprehensive overview - US Post News

Feb 04, 2025
pulisher
Feb 04, 2025

Oruka Therapeutics initiated with an Outperform at Wolfe Research - MSN

Feb 04, 2025
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Jan 26, 2025

JPMorgan Chase & Co. Has $867,000 Stake in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
pulisher
Jan 26, 2025

Assenagon Asset Management S.A. Has $527,000 Stock Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
pulisher
Jan 26, 2025

Assenagon Asset Management S.A. Cuts Stock Position in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Jan 26, 2025
pulisher
Jan 26, 2025

Analysts Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) Target Price at $54.83 - Defense World

Jan 26, 2025
pulisher
Jan 22, 2025

Spyre Therapeutics (NASDAQ:SYRE) Shares Up 9.4%Time to Buy? - MarketBeat

Jan 22, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Spyre Therapeutics Inc Stock (SYRE) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Albers Jeffrey W.
Director
Oct 25 '24
Sale
36.43
300
10,929
34,060
$36.89
price up icon 5.68%
$306.88
price up icon 0.65%
$32.96
price up icon 1.36%
$20.41
price up icon 1.05%
$102.19
price up icon 1.10%
biotechnology ONC
$247.47
price down icon 0.28%
Cap:     |  Volume (24h):