0.1173
price down icon45.92%   -0.0996
 
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Applied Therapeutics Inc stock is traded at $0.1173, with a volume of 37.84M. It is down -45.92% in the last 24 hours and down -87.11% over the past month. Applied Therapeutics Inc is a clinical-stage biopharmaceutical company, developing a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need. The company's drug compounds pipeline includes AT-007 which is a novel central nervous system, penetrant ARI that it is developing for the treatment of rare metabolic diseases, including Galactosemia and Sorbitol Dehydrogenase (SORD) Deficiency, AT-001 for the treatment of diabetic cardiomyopathy, and AT-003 for the treatment of diabetic retinopathy.
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Previous Close:
$0.2169
Open:
$0.12715
24h Volume:
37.84M
Relative Volume:
2.83
Market Cap:
$16.93M
Revenue:
-
Net Income/Loss:
$-119.76M
P/E Ratio:
-0.0869
EPS:
-1.35
Net Cash Flow:
$-55.17M
1W Performance:
-45.84%
1M Performance:
-87.11%
6M Performance:
-67.86%
1Y Performance:
-89.71%
1-Day Range:
Value
$0.11
$0.1293
1-Week Range:
Value
$0.11
$0.258
52-Week Range:
Value
$0.11
$1.50

Applied Therapeutics Inc Stock (APLT) Company Profile

Name
Name
Applied Therapeutics Inc
Name
Phone
212-220-9226
Name
Address
545 FIFTH AVENUE, SUITE 1400, NEW YORK, NY
Name
Employee
28
Name
Twitter
@Applied_Tx
Name
Next Earnings Date
2025-03-31
Name
Latest SEC Filings
Name
APLT's Discussions on Twitter

Compare APLT with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
APLT
Applied Therapeutics Inc
0.1173 31.30M 0 -119.76M -55.17M -1.35
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.04 113.14B 11.74B 3.68B 3.34B 14.19
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REGN
Regeneron Pharmaceuticals Inc
741.29 78.49B 14.25B 4.58B 3.88B 41.77
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ARGX
Argen X Se Adr
877.94 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
397.55 54.51B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
197.01 41.64B 447.02M -1.18B -906.14M -6.1812

Applied Therapeutics Inc Stock (APLT) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-12-25 Downgrade Robert W. Baird Outperform → Neutral
Dec-03-25 Downgrade Leerink Partners Outperform → Market Perform
Dec-23-24 Downgrade William Blair Outperform → Mkt Perform
Dec-02-24 Downgrade UBS Buy → Neutral
Nov-29-24 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jul-31-24 Initiated William Blair Outperform
Mar-26-24 Initiated RBC Capital Mkts Outperform
Feb-22-24 Initiated Leerink Partners Outperform
Jan-04-22 Downgrade Barclays Overweight → Equal Weight
Aug-27-21 Downgrade Goldman Neutral → Sell
Jun-25-21 Resumed Goldman Neutral
Oct-08-20 Initiated Truist Buy
Apr-22-20 Initiated Goldman Buy
Feb-27-20 Initiated Barclays Overweight
Jun-10-19 Initiated Citigroup Buy
Jun-10-19 Initiated Cowen Outperform
Jun-10-19 Initiated Robert W. Baird Outperform
View All

Applied Therapeutics Inc Stock (APLT) Latest News

pulisher
Dec 12, 2025

SHAREHOLDER ALERT: The M&A Class Action Firm Is Investigating the Merger--ALEX, DVS, DXLG, and APLT - Benzinga

Dec 12, 2025
pulisher
Dec 12, 2025

Applied Therapeutics stock rating downgraded to Neutral by Baird - Investing.com Nigeria

Dec 12, 2025
pulisher
Dec 12, 2025

Cycle buying Applied Therapeutics to develop CNS drugs - BioWorld MedTech

Dec 12, 2025
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Dec 12, 2025

S&P 500 Down 1%; Broadcom Earnings Top Views - Benzinga

Dec 12, 2025
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Dec 12, 2025

12 Health Care Stocks Moving In Friday's Intraday Session - Benzinga

Dec 12, 2025
pulisher
Dec 12, 2025

Cycle Pharma to acquire Applied Therapeutics - The Pharma Letter

Dec 12, 2025
pulisher
Dec 12, 2025

Cycle Group Holdings Limited entered into a definitive agreement to acquire Applied Therapeutics, Inc. for $13.4 million. - marketscreener.com

Dec 12, 2025
pulisher
Dec 12, 2025

Dow Rises Over 100 Points; Lululemon Posts Upbeat Q3 Earnings - Benzinga

Dec 12, 2025
pulisher
Dec 12, 2025

Applied Therapeutics (APLT) Stock News Today: Cycle Deal Details, CVR Upside, and Analyst Outlook (Dec. 12, 2025) - ts2.tech

Dec 12, 2025
pulisher
Dec 12, 2025

RBC Cuts Price Target on Applied Therapeutics to $0.25 From $1, Keeps Sector Perform, Speculative Risk - marketscreener.com

Dec 12, 2025
pulisher
Dec 12, 2025

APLT Stock Alert: Halper Sadeh LLC is Investigating Whether the Sale of Applied Therapeutics, Inc. is Fair to Shareholders - The AI Journal

Dec 12, 2025
pulisher
Dec 12, 2025

Applied Therapeutics Announces Merger with Cycle Group - TipRanks

Dec 12, 2025
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Dec 12, 2025

Applied Therapeutics plunges after UK's Cycle Group to buy co - TradingView — Track All Markets

Dec 12, 2025
pulisher
Dec 12, 2025

Why Lululemon Shares Are Trading Higher By Around 9%; Here Are 20 Stocks Moving Premarket - Benzinga

Dec 12, 2025
pulisher
Dec 12, 2025

Applied Therapeutics stock price target lowered by RBC on Cycle acquisition - Investing.com UK

Dec 12, 2025
pulisher
Dec 12, 2025

Applied Therapeutics To Be Acquired By Privately Held Cycle Group - Nasdaq

Dec 12, 2025
pulisher
Dec 11, 2025

Cycle Pharmaceuticals acquiring Applied Therapeutics - MSN

Dec 11, 2025
pulisher
Dec 11, 2025

Cycle Group to Acquire Applied Therapeutics (APLT) in Strategic Deal - GuruFocus

Dec 11, 2025
pulisher
Dec 11, 2025

Cycle Pharmaceuticals to Acquire Applied Therapeutics - The Manila Times

Dec 11, 2025
pulisher
Dec 11, 2025

Cycle to buy Applied Therapeutics (Nasdaq: APLT) in cash, CVR deal closing in Q1 2026 - Stock Titan

Dec 11, 2025
pulisher
Dec 05, 2025

Published on: 2025-12-05 04:31:49 - Newser

Dec 05, 2025
pulisher
Dec 05, 2025

Is Applied Therapeutics Inc. stock a buy on dipsJuly 2025 Gainers & Weekly Sector Rotation Insights - Newser

Dec 05, 2025
pulisher
Dec 05, 2025

Is Applied Therapeutics Inc. (2UV) stock prepared for digital transition2025 Short Interest & Verified Technical Signals - Newser

Dec 05, 2025
pulisher
Dec 04, 2025

Can Applied Therapeutics Inc. (2UV) stock surprise markets with earningsPortfolio Growth Summary & High Accuracy Buy Signal Tips - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

How Applied Therapeutics Inc. (2UV) stock moves in volatile trading sessions2025 Trade Ideas & Real-Time Stock Movement Alerts - Newser

Dec 04, 2025
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Dec 04, 2025

Can Applied Therapeutics Inc. (2UV) stock double in coming yearsWeekly Profit Recap & AI Optimized Trade Strategies - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Applied Therapeutics stock rating downgraded by Leerink Partners on cash concerns - Investing.com Nigeria

Dec 03, 2025
pulisher
Dec 03, 2025

APLT Downgraded by Leerink Partners: Key Analyst Update | APLT S - GuruFocus

Dec 03, 2025
pulisher
Dec 03, 2025

Why Applied Therapeutics Inc. (2UV) stock fits value portfoliosTrade Performance Summary & Low Volatility Stock Suggestions - Newser

Dec 03, 2025
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Dec 03, 2025

Why Applied Therapeutics Inc. (2UV) stock trades below fair value2025 Biggest Moves & Fast Moving Market Watchlists - Newser

Dec 03, 2025
pulisher
Nov 30, 2025

What analysts say about Applied Therapeutics Inc stockHead and Shoulders Patterns & Minimal Investment Trading - earlytimes.in

Nov 30, 2025
pulisher
Nov 30, 2025

Would You Still Hold Applied Therapeutics Stock If It Fell Another 30%? - Trefis

Nov 30, 2025
pulisher
Nov 28, 2025

Applied Therapeutics (APLT) Upgraded to Buy: Here's Why - MSN

Nov 28, 2025
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Nov 27, 2025

Applied Therapeutics Reports Third Quarter 2025 Financial Results - ADVFN

Nov 27, 2025
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Nov 24, 2025

Finance Watch: Poxel Pulls Back From The Brink With Recovery Plan - Citeline News & Insights

Nov 24, 2025
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Nov 24, 2025

Applied Therapeutics To Lay Off Nearly Half Its Staff, Board Explores M&A Options - MSN

Nov 24, 2025
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Nov 21, 2025

Applied Therapeutics (APLT) Stock Price, Quote, News & History - Benzinga

Nov 21, 2025
pulisher
Nov 21, 2025

Applied Therapeutics Investors Get 1st OK For $15M Deal - Law360

Nov 21, 2025
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Nov 21, 2025

Why Applied Therapeutics Inc. stock could see breakout soonMarket Trend Review & Weekly Momentum Stock Picks - newser.com

Nov 21, 2025
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Nov 20, 2025

Applied Therapeutics explores strategic alternatives amid workforce cuts By Investing.com - Investing.com Nigeria

Nov 20, 2025
pulisher
Nov 20, 2025

Applied Therapeutics Announces Corporate Updates - Investing News Network

Nov 20, 2025
pulisher
Nov 20, 2025

Applied Therapeutics, Inc. Initiates Strategic Alternatives Review - TradingView

Nov 20, 2025
pulisher
Nov 20, 2025

Applied Therapeutics explores strategic alternatives amid workforce cuts - Investing.com

Nov 20, 2025
pulisher
Nov 20, 2025

APLT Evaluates Strategic Options as Workforce Reductions Announced - GuruFocus

Nov 20, 2025
pulisher
Nov 20, 2025

APLT Evaluates FDA Meeting Outcomes for Govorestat Development P - GuruFocus

Nov 20, 2025
pulisher
Nov 20, 2025

What data driven models say about Applied Therapeutics Inc.’s future - newser.com

Nov 20, 2025
pulisher
Nov 20, 2025

Applied Therapeutics (Nasdaq: APLT) to Explore Strategic Alternatives, Reduce Workforce 46% - Stock Titan

Nov 20, 2025
pulisher
Nov 20, 2025

How Applied Therapeutics Inc. stock reacts to inflationary pressuresWeekly Trade Analysis & High Accuracy Swing Entry Alerts - newser.com

Nov 20, 2025

Applied Therapeutics Inc Stock (APLT) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Applied Therapeutics Inc Stock (APLT) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Funtleyder Leslie D.
See Remarks
Mar 04 '25
Sale
0.44
14,502
6,381
390,459
Chinoporos Constantine
See Remarks
Mar 04 '25
Sale
0.44
447
197
271,436
Funtleyder Leslie D.
See Remarks
Feb 06 '25
Sale
0.61
22,950
14,000
404,961
Perfetti Riccardo
Chief Medical Officer
Feb 06 '25
Sale
0.61
86,078
52,508
900,775
Chinoporos Constantine
See Remarks
Feb 06 '25
Sale
0.61
28,117
17,151
271,883
$38.39
price down icon 1.08%
$95.41
price down icon 0.72%
$31.31
price down icon 3.07%
$94.81
price down icon 1.24%
biotechnology ONC
$319.06
price down icon 0.55%
$197.01
price up icon 0.91%
Cap:     |  Volume (24h):