4.49
price down icon1.75%   -0.08
after-market After Hours: 4.51 0.02 +0.45%
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Orchestra Biomed Holdings Inc stock is traded at $4.49, with a volume of 111.61K. It is down -1.75% in the last 24 hours and up +3.70% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
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Previous Close:
$4.57
Open:
$4.52
24h Volume:
111.61K
Relative Volume:
0.50
Market Cap:
$262.76M
Revenue:
$33.48M
Net Income/Loss:
$-52.70M
P/E Ratio:
-3.4836
EPS:
-1.2889
Net Cash Flow:
$-49.45M
1W Performance:
-3.23%
1M Performance:
+3.70%
6M Performance:
+85.54%
1Y Performance:
+2.51%
1-Day Range:
Value
$4.46
$4.635
1-Week Range:
Value
$4.46
$4.83
52-Week Range:
Value
$2.20
$5.424

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Name
Orchestra Biomed Holdings Inc
Name
Phone
646-343-9298
Name
Address
150 UNION SQUARE DRIVE, NEW HOPE
Name
Employee
86
Name
Twitter
Name
Next Earnings Date
2026-03-30
Name
Latest SEC Filings
Name
OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ALNY, ARGX, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
OBIO icon
OBIO
Orchestra Biomed Holdings Inc
4.49 267.44M 33.48M -52.70M -49.45M -1.2889
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
453.74 115.58B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
756.73 79.23B 14.34B 4.50B 3.77B 41.56
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
328.16 43.59B 3.71B 313.75M 465.38M 2.2571
ARGX icon
ARGX
Argen X Se Adr
692.83 43.26B 4.16B 1.29B 734.26M 19.58
INSM icon
INSM
Insmed Inc
147.60 31.97B 606.42M -1.28B -997.58M -6.403

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-10-25 Initiated TD Cowen Buy
Aug-20-25 Downgrade BTIG Research Buy → Neutral
Mar-20-25 Initiated BTIG Research Buy
Jan-02-25 Initiated Barclays Overweight
Aug-22-24 Initiated H.C. Wainwright Buy
Jul-25-24 Initiated B. Riley Securities Buy
Jan-19-24 Initiated Jefferies Buy
Feb-24-23 Initiated Piper Sandler Overweight
Feb-07-23 Initiated Chardan Capital Markets Buy
View All

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

pulisher
01:41 AM

Jefferies cuts Orchestra BioMed stock price target on financing costs By Investing.com - Investing.com Australia

01:41 AM
pulisher
Mar 25, 2026

If You Invested $1,000 in Orchestra BioMed Holdings Inc (OBIO) - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

Orchestra BioMed (OBIO) to Release Earnings on Wednesday - MarketBeat

Mar 25, 2026
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Mar 24, 2026

Orchestra BioMed reports 2025 results, advances pivotal clinical trials - MSN

Mar 24, 2026
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Mar 22, 2026

Trend Report: How do insiders feel about Orchestra BioMed Holdings IncRate Cut & Precise Swing Trade Alerts - baoquankhu1.vn

Mar 22, 2026
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Mar 20, 2026

Orchestra BioMed Holdings, Inc. (OBIO) Reports Q2 Loss, Beats Revenue Estimates - MSN

Mar 20, 2026
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Mar 19, 2026

Analysts’ Top Healthcare Picks: Orchestra BioMed Holdings (OBIO), Cardinal Health (CAH) - The Globe and Mail

Mar 19, 2026
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Mar 19, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Given Average Recommendation of "Moderate Buy" by Brokerages - MarketBeat

Mar 19, 2026
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Mar 18, 2026

Aug Highlights: Will Orchestra BioMed Holdings Inc benefit from geopolitical trends2026 Trends & Risk Controlled Swing Trade Alerts - baoquankhu1.vn

Mar 18, 2026
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Mar 18, 2026

HC Wainwright Has Optimistic Outlook of OBIO Q1 Earnings - MarketBeat

Mar 18, 2026
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Mar 17, 2026

Orchestra BioMed Reports 2025 Results, Advances Pivotal Clinical Trials - MyChesCo

Mar 17, 2026
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Mar 17, 2026

Top Executive Makes Bold Insider Move at Orchestra BioMed - TipRanks

Mar 17, 2026
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Mar 16, 2026

Orchestra BioMed (NASDAQ:OBIO) Insider Purchases 10,000 Shares - MarketBeat

Mar 16, 2026
pulisher
Mar 16, 2026

Orchestra BioMed (OBIO) director David Hochman buys 10,000 shares - Stock Titan

Mar 16, 2026
pulisher
Mar 14, 2026

Orchestra BioMed (NASDAQ:OBIO) Raised to Hold at Wall Street Zen - MarketBeat

Mar 14, 2026
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Mar 13, 2026

Orchestra BioMed (OBIO) First Profitable Quarter Tests Bearish Unprofitability Narrative - simplywall.st

Mar 13, 2026
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Mar 13, 2026

Orchestra BioMed Holdings (OBIO) Receives a Buy from Chardan Capital - The Globe and Mail

Mar 13, 2026
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Mar 13, 2026

Orchestra BioMed Reports Full Year 2025 Financial Results and Provides Fourth Quarter Business Update - Sahm

Mar 13, 2026
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Mar 12, 2026

Orchestra BioMed Holdings, Inc. (OBIO) surpasses Q4 earnings and revenue estimates - MSN

Mar 12, 2026
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Mar 12, 2026

Orchestra BioMed (NASDAQ:OBIO) Receives "Buy" Rating from Chardan Capital - MarketBeat

Mar 12, 2026
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Mar 12, 2026

Chardan reiterates Orchestra BioMed stock rating on trial focus By Investing.com - Investing.com Canada

Mar 12, 2026
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Mar 12, 2026

Chardan reiterates Orchestra BioMed stock rating on trial focus - Investing.com

Mar 12, 2026
pulisher
Mar 12, 2026

Orchestra BioMed Holdings, Inc. Reports Earnings Results for the Full Year Ended December 31, 2025 - marketscreener.com

Mar 12, 2026
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Mar 12, 2026

Orchestra BioMed Holdings, Inc. (OBIO) Exceeds Expectations for Q4 Earnings and Revenue - Bitget

Mar 12, 2026
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Mar 12, 2026

Orchestra BioMed Holdings, Inc. (OBIO) Surpasses Q4 Earnings and Revenue Estimates - Yahoo Finance

Mar 12, 2026
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Mar 12, 2026

OBIO: Revenue up 1,539% to $33.5M; strong cash, pivotal trials advancing, more proceeds expected - TradingView

Mar 12, 2026
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Mar 12, 2026

Orchestra BioMed Reports $106.5 Million Cash Position and Major Financial Milestones for 2025 - Quiver Quantitative

Mar 12, 2026
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Mar 12, 2026

Orchestra BioMed Holdings 10-K Summary — Revenue: $— | EPS: $— - TradingView

Mar 12, 2026
pulisher
Mar 08, 2026

Orchestra BioMed Secures $30 Million Terumo Deal for Coronary Device Rights - MSN

Mar 08, 2026
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Mar 07, 2026

Aug Analyst Calls: Will Orchestra BioMed Holdings Inc benefit from AI trendsTrade Risk Summary & Free Accurate Trade Setup Notifications - baoquankhu1.vn

Mar 07, 2026
pulisher
Mar 07, 2026

Why Orchestra BioMed Holdings Inc. stock could outperform in 2026Portfolio Update Report & Risk Managed Trade Strategies - Naître et grandir

Mar 07, 2026
pulisher
Mar 07, 2026

Insider Sell: How resilient is Orchestra BioMed Holdings Inc. stock in market downturns2025 Key Highlights & Verified Short-Term Trading Plans - Naître et grandir

Mar 07, 2026
pulisher
Mar 06, 2026

Orchestra BioMed Holdings Inc. share price - Mint

Mar 06, 2026
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Mar 04, 2026

Market Leaders: Does Orchestra BioMed Holdings Inc outperform in volatile markets2025 Buyback Activity & Stepwise Trade Execution Plans - baoquankhu1.vn

Mar 04, 2026
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Mar 04, 2026

Orchestra BioMed to present hypertension therapy data at medical meetings By Investing.com - Investing.com Canada

Mar 04, 2026
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Mar 03, 2026

Orchestra BioMed announces presentations highlighting Avim therapy potential impact on hypertensive heart disease and heart failure at THT and CRT - marketscreener.com

Mar 03, 2026
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Mar 03, 2026

Orchestra BioMed Announces Presentations Highlighting AVIM Therapy Potential Impact on Hypertensive Heart Disease and Heart Failure at THT and CRT - The Manila Times

Mar 03, 2026
pulisher
Mar 03, 2026

Orchestra BioMed to present hypertension therapy data at medical meetings - Investing.com

Mar 03, 2026
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Mar 02, 2026

Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - 富途牛牛

Mar 02, 2026
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Feb 28, 2026

OBIO Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

Feb 28, 2026
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Feb 27, 2026

RTW INVESTMENTS, LP Increases Stake in Orchestra BioMed Holdings Inc - GuruFocus

Feb 27, 2026
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Feb 27, 2026

Medtronic (OBIO) affiliates hold 17.8% of Orchestra BioMed in amended 13G/A - Stock Titan

Feb 27, 2026
pulisher
Feb 25, 2026

Earnings Beat: How much upside does Orchestra BioMed Holdings Inc have2025 Fundamental Recap & Accurate Technical Buy Alerts - baoquankhu1.vn

Feb 25, 2026
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Feb 23, 2026

Orchestra BioMed to Present at Two Healthcare Conferences - MyChesCo

Feb 23, 2026
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Feb 23, 2026

Gains Report: Is Tuya Inc Depositary Receipt a play on infrastructure spending - baoquankhu1.vn

Feb 23, 2026
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Feb 22, 2026

OBIOOrchestra BioMed Holdings Inc Latest Stock News & Market Updates - Stock Titan

Feb 22, 2026
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Feb 22, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat

Feb 22, 2026
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Feb 21, 2026

Analysts Offer Insights on Healthcare Companies: Penumbra (PEN), Orchestra BioMed Holdings (OBIO) and Teladoc (TDOC) - The Globe and Mail

Feb 21, 2026
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Feb 20, 2026

Orchestra BioMed grants inducement stock options to nine new employees - MSN

Feb 20, 2026
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Feb 20, 2026

Will Orchestra BioMed Holdings Inc. benefit from geopolitical trendsJuly 2025 Decliners & Real-Time Volume Analysis Alerts - mfd.ru

Feb 20, 2026

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$27.35
price down icon 0.04%
$46.94
price down icon 0.19%
$53.57
price up icon 0.06%
$87.46
price down icon 1.48%
ONC ONC
$276.95
price down icon 2.29%
$147.60
price down icon 0.48%
Cap:     |  Volume (24h):