loading
Prothena Corporation Plc stock is traded at $10.36, with a volume of 455.80K. It is up +0.29% in the last 24 hours and down -4.52% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
See More
Previous Close:
$10.33
Open:
$10.4
24h Volume:
455.80K
Relative Volume:
0.71
Market Cap:
$557.68M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-10.36
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
-6.41%
1M Performance:
-4.52%
6M Performance:
+104.34%
1Y Performance:
-24.98%
1-Day Range:
Value
$10.20
$10.49
1-Week Range:
Value
$9.69
$11.30
52-Week Range:
Value
$4.32
$17.66

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRTA
Prothena Corporation Plc
10.36 556.06M 217.25M -50.92M -100.85M -1.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.04 113.14B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
741.29 78.49B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
877.94 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
397.55 54.51B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
197.01 41.64B 447.02M -1.18B -906.14M -6.1812

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
Dec 13, 2025

Birchview Capital LP Has $2.74 Million Stock Holdings in Prothena Corporation plc $PRTA - MarketBeat

Dec 13, 2025
pulisher
Dec 12, 2025

Prothena Board Member Paula Cobb Resigns - TipRanks

Dec 12, 2025
pulisher
Dec 12, 2025

Paula Cobb steps down from Prothena’s board to join Manifold Bio By Investing.com - Investing.com South Africa

Dec 12, 2025
pulisher
Dec 12, 2025

Paula Cobb steps down from Prothena’s board to join Manifold Bio - Investing.com Australia

Dec 12, 2025
pulisher
Dec 12, 2025

Prothena Announces Board of Directors Update - Business Wire

Dec 12, 2025
pulisher
Dec 12, 2025

What analysts say about Prothena Corporation plc stockMean Reversion Trades & Free Harness Proven Investment Plans - earlytimes.in

Dec 12, 2025
pulisher
Dec 12, 2025

Prothena Corporation plc $PRTA Shares Bought by Federated Hermes Inc. - MarketBeat

Dec 12, 2025
pulisher
Dec 11, 2025

Liquidity Mapping Around (PRTA) Price Events - news.stocktradersdaily.com

Dec 11, 2025
pulisher
Dec 10, 2025

Ready to Jump After Recent Trade: Prothena Corporation plc (PRTA) - setenews.com

Dec 10, 2025
pulisher
Dec 08, 2025

Prothena (PRTA) price target increased by 10.91% to 20.74 - MSN

Dec 08, 2025
pulisher
Dec 06, 2025

How the Narrative Surrounding Prothena Is Changing After New Pipeline and Valuation Updates - Yahoo Finance

Dec 06, 2025
pulisher
Dec 06, 2025

Prothena (PRTA) Price Target Increased by 10.91% to 20.74 - Nasdaq

Dec 06, 2025
pulisher
Dec 05, 2025

Will Prothena Corporation plc stock outperform international peersTrade Entry Summary & Breakout Confirmation Trade Signals - Newser

Dec 05, 2025
pulisher
Dec 04, 2025

Prothena (NASDAQ:PRTA) Stock Price Up 7.4%Here's Why - MarketBeat

Dec 04, 2025
pulisher
Dec 03, 2025

Are Smart Investors Making the Right Decision? Prothena Corporation plc (PRTA) - setenews.com

Dec 03, 2025
pulisher
Dec 02, 2025

Prothena Corp (PRTA) Stock Analysis Report | Ratings, Financials & Performance - Benzinga

Dec 02, 2025
pulisher
Dec 02, 2025

Citizens Jmp Forecasts Strong Price Appreciation for Prothena (NASDAQ:PRTA) Stock - MarketBeat

Dec 02, 2025
pulisher
Dec 02, 2025

Prothena (NASDAQ:PRTA) Price Target Raised to $19.00 at Citizens Jmp - Defense World

Dec 02, 2025
pulisher
Dec 01, 2025

Prothena stock price target raised to $19 from $11 at Citizens - Investing.com Nigeria

Dec 01, 2025
pulisher
Dec 01, 2025

Prothena stock price target raised to $19 from $11 at Citizens By Investing.com - Investing.com South Africa

Dec 01, 2025
pulisher
Dec 01, 2025

Citizens Raises Price Target for Prothena Corp (PRTA) to $19.00 - GuruFocus

Dec 01, 2025
pulisher
Nov 30, 2025

Prothena Corporation plc Stock Analysis and ForecastFundamental Stock Analysis & Double Digit Portfolio Growth - earlytimes.in

Nov 30, 2025
pulisher
Nov 30, 2025

Why (PRTA) Price Action Is Critical for Tactical Trading - news.stocktradersdaily.com

Nov 30, 2025
pulisher
Nov 29, 2025

Aug PreEarnings: Why Prothena Corporation plc stock remains undervaluedRecession Risk & Target Return Focused Stock Picks - BỘ NỘI VỤ

Nov 29, 2025
pulisher
Nov 25, 2025

DCF Advisers LLC Lowers Stock Position in Prothena Corporation plc $PRTA - MarketBeat

Nov 25, 2025
pulisher
Nov 23, 2025

Prothena Corporation plc (NASDAQ:PRTA) Given Average Recommendation of "Hold" by Brokerages - MarketBeat

Nov 23, 2025
pulisher
Nov 22, 2025

Prothena (NASDAQ:PRTA) Raised to "Strong-Buy" at Chardan Capital - MarketBeat

Nov 22, 2025
pulisher
Nov 22, 2025

Prothena (NASDAQ:PRTA) Upgraded at Chardan Capital - Defense World

Nov 22, 2025
pulisher
Nov 21, 2025

How Prothena Corporation plc stock performs during Fed tightening cyclesJuly 2025 Reactions & Low Risk Entry Point Guides - newser.com

Nov 21, 2025
pulisher
Nov 20, 2025

Prothena Announces Poster Presentation on its TDP-43 CYTOPE® Program at Neuroscience 2025 - BioSpace

Nov 20, 2025
pulisher
Nov 19, 2025

Will Prothena Corporation plc stock see PE expansionQuarterly Growth Report & Free Reliable Trade Execution Plans - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Prothena Shareholders Approve Capital Reduction Proposal - TipRanks

Nov 19, 2025
pulisher
Nov 19, 2025

Prothena presents TDP-43 CYTOPE data showing promise for ALS treatment - Investing.com Australia

Nov 19, 2025
pulisher
Nov 19, 2025

Prothena (PRTA) Highlights Breakthrough in Drug Delivery at Neur - GuruFocus

Nov 19, 2025
pulisher
Nov 19, 2025

Prothena announces poster presentation on its TDP-43 Cytope® program at neuroscience 2025 - MarketScreener

Nov 19, 2025
pulisher
Nov 19, 2025

Prothena Announces Poster Presentation On Its TDP-43 Cytope® Program At Neuroscience 2025 - TradingView

Nov 19, 2025
pulisher
Nov 19, 2025

What’s the recovery path for long term holders of Prothena Corporation plcPortfolio Growth Summary & Weekly Top Gainers Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Prothena Corporation plc stock see insider buyingWeekly Trend Summary & Community Shared Stock Ideas - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Understanding Momentum Shifts in (PRTA) - news.stocktradersdaily.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Prothena Corporation plc stock maintain momentum in 2025 - newser.com

Nov 19, 2025
pulisher
Nov 16, 2025

Market reaction to Prothena Corporation plc’s recent newsWeekly Market Summary & Fast Entry High Yield Tips - newser.com

Nov 16, 2025
pulisher
Nov 15, 2025

What MACD and RSI say about Prothena Corporation plcTrade Performance Summary & Community Verified Watchlist Alerts - newser.com

Nov 15, 2025

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Prothena Corporation Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
EcoR1 Capital, LLC
10% Owner
May 06 '25
Sale
7.64
1,984,053
15,164,712
5,304,596
EcoR1 Capital, LLC
10% Owner
May 05 '25
Sale
8.11
977,693
7,930,166
7,288,649
SCULLY WILLIAM P
10% Owner
Jan 14 '25
Buy
12.79
100,000
1,279,040
735,993
SCULLY WILLIAM P
10% Owner
Dec 18 '24
Buy
13.93
73,436
1,022,670
1,297,693
SCULLY WILLIAM P
10% Owner
Dec 31 '24
Buy
13.01
32,000
416,393
650,193
SCULLY WILLIAM P
10% Owner
Dec 20 '24
Buy
15.91
2,000
31,813
618,693
$38.39
price down icon 1.08%
$95.41
price down icon 0.72%
$31.31
price down icon 3.07%
$94.81
price down icon 1.24%
biotechnology ONC
$319.06
price down icon 0.55%
$197.01
price up icon 0.91%
Cap:     |  Volume (24h):