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Prothena Corporation Plc stock is traded at $10.53, with a volume of 349.61K. It is down -1.86% in the last 24 hours and up +6.35% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
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Previous Close:
$10.75
Open:
$10.755
24h Volume:
349.61K
Relative Volume:
0.41
Market Cap:
$567.37M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-10.53
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
+1.74%
1M Performance:
+6.35%
6M Performance:
+24.12%
1Y Performance:
-36.64%
1-Day Range:
Value
$10.40
$11.17
1-Week Range:
Value
$10.34
$11.69
52-Week Range:
Value
$4.32
$18.77

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
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PRTA
Prothena Corporation Plc
10.54 578.67M 217.25M -50.92M -100.85M -1.00
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VRTX
Vertex Pharmaceuticals Inc
425.62 109.11B 11.39B 3.64B 3.50B 13.99
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REGN
Regeneron Pharmaceuticals Inc
641.93 68.50B 14.25B 4.58B 3.88B 41.77
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ALNY
Alnylam Pharmaceuticals Inc
432.49 60.25B 3.21B 43.57M 221.36M 0.2405
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ARGX
Argen X Se Adr
823.27 50.39B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
184.13 40.44B 447.02M -1.18B -868.57M -6.1812

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
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Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
09:21 AM

Is this a good reentry point in Prothena Corporation plcAnalyst Downgrade & High Yield Stock Recommendations - newser.com

09:21 AM
pulisher
08:23 AM

Should you hold or exit Prothena Corporation plc nowPortfolio Value Summary & Expert Verified Movement Alerts - newser.com

08:23 AM
pulisher
07:59 AM

Should you wait for a breakout in Prothena Corporation plcPortfolio Value Summary & Short-Term Swing Trade Alerts - newser.com

07:59 AM
pulisher
07:39 AM

Signal strength of Prothena Corporation plc stock in tech scannersInflation Watch & Fast Entry Momentum Alerts - newser.com

07:39 AM
pulisher
07:20 AM

Will Prothena Corporation plc stock see insider buyingMarket Growth Report & Fast Moving Stock Trade Plans - newser.com

07:20 AM
pulisher
06:29 AM

What MACD and RSI say about Prothena Corporation plc2025 Market Sentiment & Risk Adjusted Buy and Sell Alerts - newser.com

06:29 AM
pulisher
06:11 AM

How Prothena Corporation plc stock trades before earnings2025 Support & Resistance & Low Risk High Reward Trade Ideas - newser.com

06:11 AM
pulisher
06:05 AM

What’s the recovery path for long term holders of Prothena Corporation plcQuarterly Risk Review & AI Optimized Trading Strategy Guides - newser.com

06:05 AM
pulisher
05:15 AM

Using portfolio simulators with Prothena Corporation plc includedTrade Exit Report & Safe Capital Growth Plans - newser.com

05:15 AM
pulisher
03:36 AM

Market reaction to Prothena Corporation plc’s recent newsWeekly Trade Summary & Real-Time Sentiment Analysis - newser.com

03:36 AM
pulisher
12:43 PM

Risk vs reward if holding onto Prothena Corporation plcWeekly Stock Summary & Free Weekly Chart Analysis and Trade Guides - newser.com

12:43 PM
pulisher
Nov 02, 2025

Prothena (PRTA) to Release Quarterly Earnings on Thursday - MarketBeat

Nov 02, 2025
pulisher
Nov 01, 2025

Will Prothena Corporation plc stock recover faster than marketMarket Movement Recap & AI Enhanced Trading Signals - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

What analysts say about Prothena Corporation plc stockFlag and Pennant Patterns & Accelerated Capital Growth - earlytimes.in

Nov 01, 2025
pulisher
Oct 31, 2025

Will Prothena Corporation plc stock reach all time highs in 2025Take Profit & Technical Pattern Based Buy Signals - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Will Prothena Corporation plc stock see PE expansionJuly 2025 Closing Moves & Fast Gain Stock Trading Tips - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Applying chart zones and confluence areas to Prothena Corporation plcJuly 2025 Market Mood & Real-Time Volume Trigger Notifications - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

What to expect from Prothena Corporation plc in the next 30 daysWeekly Stock Recap & Reliable Intraday Trade Alerts - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Prothena to Report Third Quarter 2025 Financial Results on November 6 - BioSpace

Oct 31, 2025

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corporation Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
EcoR1 Capital, LLC
10% Owner
May 06 '25
Sale
7.64
1,984,053
15,164,712
5,304,596
EcoR1 Capital, LLC
10% Owner
May 05 '25
Sale
8.11
977,693
7,930,166
7,288,649
SCULLY WILLIAM P
10% Owner
Jan 14 '25
Buy
12.79
100,000
1,279,040
735,993
SCULLY WILLIAM P
10% Owner
Dec 18 '24
Buy
13.93
73,436
1,022,670
1,297,693
SCULLY WILLIAM P
10% Owner
Dec 31 '24
Buy
13.01
32,000
416,393
650,193
SCULLY WILLIAM P
10% Owner
Dec 20 '24
Buy
15.91
2,000
31,813
618,693
$37.49
price down icon 0.27%
$28.64
price up icon 0.10%
$100.80
price up icon 8.05%
$104.06
price up icon 0.13%
biotechnology ONC
$312.04
price up icon 0.52%
$183.82
price down icon 3.02%
Cap:     |  Volume (24h):