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Prothena Corporation Plc stock is traded at $5.9803, with a volume of 1.01M. It is up +4.56% in the last 24 hours and down -16.99% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
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Previous Close:
$5.70
Open:
$5.7
24h Volume:
1.01M
Relative Volume:
0.71
Market Cap:
$283.13M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-5.9803
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
+16.86%
1M Performance:
-16.99%
6M Performance:
-50.13%
1Y Performance:
-69.50%
1-Day Range:
Value
$5.67
$6.03
1-Week Range:
Value
$4.95
$6.03
52-Week Range:
Value
$4.32
$25.42

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

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PRTA
Prothena Corporation Plc
5.98 283.13M 217.25M -50.92M -100.85M -1.00
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ARGX
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545.29 35.14B 2.58B 1.06B -1.28B 16.33
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ONC
Beone Medicines Ltd Adr
255.78 28.51B 3.81B -644.79M -669.77M -6.24

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
04:38 AM

Prothena (NASDAQ:PRTA) Shares Pass Below 200 Day Moving Average – Time to Sell? - Defense World

04:38 AM
pulisher
Jun 17, 2025

Roche’s Phase 3 Move Boosts Outlook for Prothena Corporation plc (PRTA) - Insider Monkey

Jun 17, 2025
pulisher
Jun 16, 2025

(PRTA) Trading Signals - news.stocktradersdaily.com

Jun 16, 2025
pulisher
Jun 16, 2025

Financial Analysis: Prothena Corporation plc (PRTA)’s Ratios Unveil Key Insights - DWinneX

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena stock rises on Parkinson's trial update (PRTA:NASDAQ) - Seeking Alpha

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena’s Prasinezumab Advances to Phase III for Parkinson’s - TipRanks

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena partner Roche advances Parkinson’s drug to phase 3 By Investing.com - Investing.com Nigeria

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena’s Partner Roche to Advance Prasinezumab into Phase III Development for Early-Stage Parkinson's Disease - BioSpace

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena's Partner to Advance Potential Parkinson's Treatment to Phase 3 Development - marketscreener.com

Jun 16, 2025
pulisher
Jun 16, 2025

Prothena's Partner Roche to Advance Prasinezumab into Phase III - GuruFocus

Jun 16, 2025
pulisher
Jun 14, 2025

Prothena’s SWOT analysis: stock faces challenges after trial setback By Investing.com - Investing.com South Africa

Jun 14, 2025
pulisher
Jun 14, 2025

Prothena’s SWOT analysis: stock faces challenges after trial setback - Investing.com

Jun 14, 2025
pulisher
Jun 11, 2025

Cantor Fitzgerald Forecasts Prothena FY2026 Earnings - Defense World

Jun 11, 2025
pulisher
Jun 09, 2025

Two Sigma Investments LP Buys 27,887 Shares of Prothena Co. plc (NASDAQ:PRTA) - Defense World

Jun 09, 2025
pulisher
Jun 06, 2025

Prothena Co. plc (NASDAQ:PRTA) Short Interest Update - Defense World

Jun 06, 2025
pulisher
Jun 05, 2025

Bank of America Corp DE Purchases 36,944 Shares of Prothena Co. plc (NASDAQ:PRTA) - Defense World

Jun 05, 2025
pulisher
Jun 04, 2025

(PRTA) Technical Data - news.stocktradersdaily.com

Jun 04, 2025
pulisher
Jun 03, 2025

Millennium Management LLC Has $1.70 Million Holdings in Prothena Co. plc (NASDAQ:PRTA) - Defense World

Jun 03, 2025
pulisher
Jun 03, 2025

PROTHENA LEAD PLAINTIFF DEADLINE ALERT: Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses Exceeding $50,000 In Prothena Corporation plc To Contact The Firm - ACCESS Newswire

Jun 03, 2025
pulisher
Jun 02, 2025

ProShare Advisors LLC Buys 3,312 Shares of Prothena Co. plc (NASDAQ:PRTA) - Defense World

Jun 02, 2025
pulisher
May 31, 2025

Piper Sandler Reduces Prothena (PRTA) Price Target to $81 from $110 Following AFFIRM-AL Trial Discontinuation - MSN

May 31, 2025
pulisher
May 31, 2025

Chardan Lowers Prothena (PRTA) Price Target Following AFFIRM-AL Trial Failure - MSN

May 31, 2025
pulisher
May 31, 2025

Prothena Co. plc (NASDAQ:PRTA) Given Consensus Recommendation of “Hold” by Brokerages - Defense World

May 31, 2025
pulisher
May 31, 2025

Chardan Capital Decreases Earnings Estimates for Prothena - Defense World

May 31, 2025
pulisher
May 30, 2025

Citizens JMP Slashes Prothena (PRTA) to $29 from $78 After AFFIRM-AL Trial Fails - MSN

May 30, 2025
pulisher
May 30, 2025

H.C. Wainwright Maintains Buy Rating on Prothena Corporation (NASDAQ:PRTA), Cuts PT - Insider Monkey

May 30, 2025
pulisher
May 30, 2025

FY2027 EPS Estimates for Prothena Decreased by HC Wainwright - Defense World

May 30, 2025
pulisher
May 30, 2025

Prothena (NASDAQ:PRTA) Given “Underperform” Rating at Bank of America - Defense World

May 30, 2025
pulisher
May 29, 2025

Bank of America Reiterates “Underperform” Rating for Prothena (NASDAQ:PRTA) - Defense World

May 29, 2025
pulisher
May 29, 2025

Bank of America Reaffirms “Underperform” Rating for Prothena (NASDAQ:PRTA) - Defense World

May 29, 2025
pulisher
May 29, 2025

Prothena (NASDAQ:PRTA) Receives Underperform Rating from Bank of America - Defense World

May 29, 2025
pulisher
May 29, 2025

The Prothena Corporation plc (NASDAQ:PRTA) Analysts Have Been Trimming Their Sales Forecasts - simplywall.st

May 29, 2025
pulisher
May 29, 2025

BofA cuts Prothena stock rating, slashes target to $4 By Investing.com - Investing.com Nigeria

May 29, 2025
pulisher
May 28, 2025

Prothena Corp (PRTA) Sees Downgrade and Price Target Cut by B of A Securities | PRTA Stock News - GuruFocus

May 28, 2025
pulisher
May 28, 2025

Oppenheimer Downgrades Prothena Corporation (NASDAQ:PRTA) to Perform from Outperform - Insider Monkey

May 28, 2025
pulisher
May 28, 2025

BofA Securities Downgrades Prothena to Underperform From Neutral, $4 Price Target - marketscreener.com

May 28, 2025
pulisher
May 28, 2025

Prothena (PRTA) Faces Downgrade After Clinical Trial Setback | P - GuruFocus

May 28, 2025
pulisher
May 28, 2025

Prothena (PRTA) Faces Downgrade After Clinical Trial Setback | PRTA Stock News - GuruFocus

May 28, 2025
pulisher
May 28, 2025

Prothena's Late-Stage Study for AL Amyloidosis Fails, Stock Down - MSN

May 28, 2025
pulisher
May 28, 2025

Prothena (PRTA) Downgraded by BofA Analyst with Lower Price Targ - GuruFocus

May 28, 2025
pulisher
May 28, 2025

Prothena (NASDAQ:PRTA) Price Target Lowered to $81.00 at Piper Sandler - Defense World

May 28, 2025
pulisher
May 28, 2025

Prothena (NASDAQ:PRTA) Price Target Cut to $29.00 by Analysts at JMP Securities - Defense World

May 28, 2025
pulisher
May 28, 2025

Prothena (NASDAQ:PRTA) Lowered to Hold Rating by Jefferies Financial Group - Defense World

May 28, 2025
pulisher
May 28, 2025

Prothena (NASDAQ:PRTA) Given New $14.00 Price Target at HC Wainwright - Defense World

May 28, 2025
pulisher
May 28, 2025

Traders Purchase High Volume of Put Options on Prothena (NASDAQ:PRTA) - Defense World

May 28, 2025
pulisher
May 27, 2025

Oppenheimer cuts Prothena stock rating after trial setback By Investing.com - Investing.com Nigeria

May 27, 2025
pulisher
May 27, 2025

Prothena (PRTA) Shares Plunge After Key Trial Setback - GuruFocus

May 27, 2025
pulisher
May 27, 2025

Prothena: Despite Phase 3 Trial Failure, Other Neurodegenerative Programs In Place (PRTA) - Seeking Alpha

May 27, 2025
pulisher
May 27, 2025

Peninsula biotech Prothena falters — again — and layoffs are on the waySan Francisco Business Times - The Business Journals

May 27, 2025
pulisher
May 27, 2025

Prothena Shares Fall, Stock Downgraded by Multiple Research Firms After Birtamimab Development Discontinued - marketscreener.com

May 27, 2025
pulisher
May 27, 2025

Prothena Corp (PRTA) Downgraded by Oppenheimer | PRTA Stock News - GuruFocus

May 27, 2025

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corporation Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
EcoR1 Capital, LLC
10% Owner
May 06 '25
Sale
7.64
1,984,053
15,164,712
5,304,596
EcoR1 Capital, LLC
10% Owner
May 05 '25
Sale
8.11
977,693
7,930,166
7,288,649
SCULLY WILLIAM P
10% Owner
Jan 14 '25
Buy
12.79
100,000
1,279,040
735,993
SCULLY WILLIAM P
10% Owner
Dec 18 '24
Buy
13.93
73,436
1,022,670
1,297,693
SCULLY WILLIAM P
10% Owner
Dec 31 '24
Buy
13.01
32,000
416,393
650,193
SCULLY WILLIAM P
10% Owner
Dec 20 '24
Buy
15.91
2,000
31,813
618,693
$21.77
price down icon 1.59%
$34.55
price down icon 0.01%
$19.79
price down icon 0.60%
$99.95
price down icon 0.21%
$104.39
price down icon 0.28%
biotechnology ONC
$256.82
price up icon 0.56%
Cap:     |  Volume (24h):